Patents by Inventor Patrick Alexandre
Patrick Alexandre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240055170Abstract: A multipole electromagnet for injecting particles, including a hollow duct extending along a longitudinal axis, and a plurality of wire conductors that are placed parallel or substantially parallel to the longitudinal axis along the duct, electrically connected in series and arranged to conduct electric current. The directions of the electric current flowing through the wire conductors are symmetric about a first plane of symmetry. The wire conductors are distributed in multiple carrier planes that are parallel or substantially parallel to the first plane of symmetry, including two main carrier planes that are symmetric about the first plane of symmetry and located outside the hollow, each main carrier plane carrying wire conductors that conduct the electric current in the first direction and wire conductors that conduct the electric current in the second direction opposite the first direction.Type: ApplicationFiled: May 13, 2022Publication date: February 15, 2024Inventors: Patrick ALEXANDRE, Rachid BEN EL FEKIH
-
Publication number: 20240003603Abstract: A heating, ventilation, air conditioning, and refrigeration (HVACR) system includes a suction heat exchanger configured to add heat to working fluid prior to entering the compressor, so as to support the generation of superheat by the HVACR system. The superheat can be controlled to achieve desired levels, so as to support the separation of lubricant from working fluid of the HVACR system. The suction heat exchanger can heat the working fluid passing to the suction of the compressor by exchanging heat with working fluid sourced from between the lubricant separator and the condenser. The suction heat exchanger can further be used as a receiver for controlling the charge of working fluid circulating in the HVACR system.Type: ApplicationFiled: June 30, 2022Publication date: January 4, 2024Inventors: Thibaut Gerson, Raphael Gury, Jon P. Hartfield, Laurent Maire Richard, Patrick Alexandre, Sebastien Montemont, Thierry Choffe
-
Patent number: 11712521Abstract: An injection nozzle for a needleless injection device includes at least one outlet conduit extending parallel to an injection axis (B). The outlet conduit(s) include a first conduit portion having a first section, a second conduit portion having a second section, the first section being larger than the second section, and a connecting portion between the first conduit portion and the second conduit portion. The connecting portion is inclined at an angle between 70° and 90° with respect to the injection axis (B).Type: GrantFiled: April 11, 2019Date of Patent: August 1, 2023Assignee: CROSSJECTInventors: Christophe Auriel, Patrick Alexandre, Benoit Guichard, Jennifer Ascani, M. Abdel Tazibt
-
Publication number: 20190231981Abstract: An injection nozzle for a needleless injection device includes at least one outlet conduit extending parallel to an injection axis (B). The outlet conduit(s) include a first conduit portion having a first section, a second conduit portion having a second section, the first section being larger than the second section, and a connecting portion between the first conduit portion and the second conduit portion. The connecting portion is inclined at an angle between 70° and 90° with respect to the injection axis (B).Type: ApplicationFiled: April 11, 2019Publication date: August 1, 2019Applicant: CROSSJECTInventors: Christophe AURIEL, Patrick ALEXANDRE, Benoit GUICHARD, Jennifer ASCANI, Abdel M. TAZIBT
-
Patent number: 8784371Abstract: Needleless injection device (1) comprising a gas generator (2), a reservoir (5) in the form of a glass tube (6) closed by an upstream stopper (7) and a downstream stopper (8) between which a liquid active principle (9) is accommodated, and an injection nozzle (15) equipped with a receptacle (19) and with at least one peripheral injection conduit (20), said tube (6) having, at one of its ends, a flange (4) via which it is in contact with said nozzle (15). The main feature of this needleless injection device (1) is that the tube (6) has a cylindrical inner channel with an upstream part (21) which is continued by a downstream part (22) of smaller diameter, said downstream part (22) being surrounded by said flange (4) and opening into the receptacle (19).Type: GrantFiled: August 31, 2007Date of Patent: July 22, 2014Assignee: CROSSJECTInventor: Patrick Alexandre
-
Patent number: 8197440Abstract: The present invention relates to a needleless injection device (1) comprising a reservoir (3), obturated by an upstream stopper (4) and a downstream stopper (5) between which a liquid active principle (6) is accommodated, and a receptacle (7) comprising at least one injection conduit (8), said receptacle comprising a cavity (10) whose height is equal to the distance traveled by the downstream stopper before each injection conduit is opened, —the height of the cavity in millimeters being between a minimum height and a maximum height, respectively defined by the following relationships, •minimum height=3, •maximum height=15×exp. (?(V/9)2)+10, where V is the initial speed of ascent of the pressure profile expressed in bar per microsecond, —the ratio between the length of each injection conduit and the height of the cavity being between 1 and 2.Type: GrantFiled: June 26, 2007Date of Patent: June 12, 2012Assignee: CrossjectInventor: Patrick Alexandre
-
Patent number: 8070714Abstract: The technical field of the invention is that of needleless pre-filled disposable syringes, operating with a gas generator, and used for intradermal, subcutaneous and intramuscular injections, of a liquid active principle for therapeutic use in human and veterinary medicine. The inventive needleless syringes use a reservoir (5) consisting of a tube (6) closed by an upstream plug-piston (7) and a downstream plug-piston (8) between which is contained the liquid active principle. Said needleless syringes are characterized in that they are capable of injecting a variable amount of liquid active principle (9) by adapting, through displacement of the downstream plug-piston (8) in the tube (6) the volume included between the two plug-pistons (7,8) to the amount of active principle (9) to be injected.Type: GrantFiled: February 29, 2008Date of Patent: December 6, 2011Assignee: CrossjectInventors: Patrick Alexandre, Bernard Brouquieres, Denis Roller
-
Patent number: 7981075Abstract: A needleless injection device used for intradermal, subcutaneous and intramuscular injections is disclosed. The device includes a pyrotechnic gas generator, at least one piston, a reserve of liquid active principle and an injection nozzle. The generator includes a pyrotechnic charge composed of a central energetic material that is surrounded by a second peripheral energetic material. The entire outer surface of the central energetic material contacts the inner surface of the peripheral energetic material. The two energetic materials have different rates of combustion.Type: GrantFiled: September 20, 2005Date of Patent: July 19, 2011Assignee: CrossjectInventors: Patrick Alexandre, Bernard Brouquieres, Philippe Gautier, Christiane Reynaud
-
Patent number: 7798989Abstract: The invention relates to needleless syringe for injecting an active liquid principle. The inventive syringe comprises a container (3) closed by a movable shutter and containing the injectable liquid. Said container is initially insulated from an injector-receptacle provided with a cylinder bore (10) in which a downstream shutter is arranged and which comprises at least one protuberance reducing the section with respect to the upstream opening of the bore. The aim of said invention is to damp and prevent the downstream shutter bounce when it is disposed in the bore (10) of the receptacle.Type: GrantFiled: January 11, 2005Date of Patent: September 21, 2010Assignee: CrossjectInventors: Patrick Alexandre, Georges Baud, Bernard Brouquieres, Laurent D'Emmanuelle, Denis Roller
-
Publication number: 20100076375Abstract: Needleless injection device (1) comprising a gas generator (2), a reservoir (5) in the form of a glass tube (6) closed by an upstream stopper (7) and a downstream stopper (8) between which a liquid active principle (9) is accommodated, and an injection nozzle (15) equipped with a receptacle (19) and with at least one peripheral injection conduit (20), said tube (6) having, at one of its ends, a flange (4) via which it is in contact with said nozzle (15). The main feature of this needleless injection device (1) is that the tube (6) has a cylindrical inner channel with an upstream part (21) which is continued by a downstream part (22) of smaller diameter, said downstream part (22) being surrounded by said flange (4) and opening into the receptacle (19).Type: ApplicationFiled: August 31, 2007Publication date: March 25, 2010Applicant: CROSSJECTInventor: Patrick Alexandre
-
Publication number: 20090326446Abstract: The present invention relates to a needleless injection device (1) comprising a reservoir (3), obturated by an upstream stopper (4) and a downstream stopper (5) between which a liquid active principle (6) is accommodated, and a receptacle (7) comprising at least one injection conduit (8), said receptacle comprising a cavity (10) whose height is equal to the distance travelled by the downstream stopper before each injection conduit is opened, —the height of the cavity in millimetres being between a minimum height and a maximum height, respectively defined by the following relationships, •minimum height=3, •maximum height=15×exp. (?(V/9)2)+10, where V is the initial speed of ascent of the pressure profile expressed in bar per microsecond, —the ratio between the length of each injection conduit and the height of the cavity being between 1 and 2.Type: ApplicationFiled: June 26, 2007Publication date: December 31, 2009Applicant: CROSSJECTInventor: Patrick Alexandre
-
Patent number: 7559917Abstract: The invention concerns the field of pre-filled and disposable needleless syringes, operating with a gas generator and used for intradermal, subcutaneous and intramuscular injections of a liquid active principle for therapeutic purposes in human and veterinary medicine. Said injection device (1) is mainly characterized in that it has a free pressuring space (26) around the reservoir (20) of the active principle (17) so that the gases produced by the gas generator (4) instantly penetrate said pressurizing space (26), compressing said reservoir (20) just before causing the plunger to move (18) to expel the liquid active principle (17). During said displacement, the reservoir (20) is subjected to a state of equal pressure.Type: GrantFiled: July 27, 2001Date of Patent: July 14, 2009Assignee: CrossjectInventors: Patrick Alexandre, Bernard Brouquieres, Bernard Pech
-
Patent number: 7559920Abstract: The invention relates to an injection device which may or may not be equipped with a needle, comprising an injection nozzle and a tube which is intended to receive the active substance to be injected, whereby the tube is fixed to the nozzle using connecting means. The inventive device is characterized in that the aforementioned connecting means comprise at least three identical bosses which are solidly connected to the nozzle. Moreover, each of said bosses comprises an inclined part which terminates in a flange, said flange co-operating with a collar which is formed on the tube and acts as a backstop for the tube when the latter is connected to the nozzle.Type: GrantFiled: April 15, 2004Date of Patent: July 14, 2009Assignee: CrossjectInventors: Patrick Alexandre, Georges Baud, Bernard Brouquieres
-
Patent number: 7513885Abstract: The invention concerns the field of needleless syringe having an injector with several ducts. The problem that needs to be solved is the long term compatibility of the injector with the liquid active principle. For that purpose the syringe (1) comprises a cylindrical reservoir (2), closed at its upstream part by a closure element (3) capable of being moved by driving means (70), and closed at its downstream part by an injector (4) comprising at least an injection duct and said reservoir being secured to the body (8) of the syringe, said syringe is such that the diaphragm (5), compatible with the active principle, isolates the latter from the injector (4) and said diaphragm can be passed through by the liquid (6) when pressurized for injection.Type: GrantFiled: May 20, 2004Date of Patent: April 7, 2009Assignee: CrossjectInventors: Alain Navelier, Patrick Alexandre, Bernard Brouquieres, Philippe Gautier
-
Patent number: 7500960Abstract: The invention relates to a method of assembling a needleless injection device (1), whereby a plurality of elements forming a circuit of elements is assembled to a body (2). The aforementioned circuit comprises elements such as an initiation device, a receptacle (5) containing an active agent to be injected, and an active agent injection system. The inventive method is characterised in that it comprises a step in which a gas-generating cartridge (6), which is adapted to the nature and/or quantity of active agent to be injected as well as to the skin penetration depth desired for same, is inserted directly into the circuit of elements, independently of said elements, from outside the body (2). The invention also relates to a needleless injection device (1).Type: GrantFiled: March 18, 2004Date of Patent: March 10, 2009Assignee: CrossjectInventors: Patrick Alexandre, Georges Baud, Bernard Brouquieres, Philippe Gautier
-
Patent number: 7455655Abstract: The invention relates to a needleless injection device (1) comprising a body (2) which supports and/or defines a plurality of elements that form a circuit of elements. The aforementioned circuit comprises, from upstream towards downstream, an initiation device which is associated with a pyrotechnic gas generator, a receptacle (5) housing a liquid active agent that is to be injected, and an active agent injection system. According to the invention, the pyrotechnic gas generator comprises a pyrotechnic charge (62) which is placed in a combustion chamber (4). The inventive device is characterised in that it comprises at least one device for regulating the gas pressure level in the combustion chamber (4).Type: GrantFiled: March 18, 2004Date of Patent: November 25, 2008Assignee: CrossjectInventors: Patrick Alexandre, Bernard Brouquieres, David Desailly
-
Publication number: 20080214997Abstract: The technical field of the invention is that of pre-filled and disposable needleless syringes, used for intradermal, subcutaneous and intramuscular injections of liquid active principle for therapeutic use in human and veterinary medicine. The inventive syringes (1) are mainly characterized in that they function with a pyrotechnic charge (6) consisting of a mixture of powder with high burning rate and a powder with low burning rate. Indeed, the combustion of the powder with a high burning rate enables to communicate instantly, through a piston (3), a very high speed to the active principle (4), whereas the combustion of the powder with a low burning rate enables to maintain a threshold pressure level to proceed with the injection, so as to ensure that the active principle (4) penetrates through the skin. Thus, the injection is properly and homogeneously without any loss of active liquid (4).Type: ApplicationFiled: March 6, 2008Publication date: September 4, 2008Applicant: CROSSJECTInventors: Patrick Alexandre, Patrick Cognot, Joel Lafforgue, Denis Roller
-
Patent number: 7404808Abstract: The invention relates to the realm of needleless syringes used for injecting liquid active substances. Said syringe comprises a reservoir that is enclosed by means of displaceable plugs which trap the liquid. The reservoir is initially isolated from an injector-receptacle (37) which is provided with at least two peripheral injection conduits (38) that are arranged outside the receptacle (37). Said receptacle (37) encompasses a pocket bore (31) which accommodates the plug located downstream such that the optimized inlets (39) of the conduits are unobstructed. The face of the receptacle (37), which is located upstream, comprises a multilobed sealing joint (34) which is disposed parallel to and as close as possible to the edges of the bore (31) and the inlets (39). The aim of the invention is to create an injector-receptacle (37) that is optimized regarding discharging and the resistance thereof to the injection pressure.Type: GrantFiled: April 9, 2004Date of Patent: July 29, 2008Assignee: CrossjectInventors: Patrick Alexandre, Georges Baud, Bernard Brouquieres
-
Publication number: 20080154189Abstract: The technical field of the invention is that of needleless pre-filled disposable syringes, operating with a gas generator, and used for intradermal, subcutaneous and intramuscular injections, of a liquid active principle for therapeutic use in human and veterinary medicine. The inventive needleless syringes use a reservoir (5) consisting of a tube (6) closed by an upstream plug-piston (7) and a downstream plug-piston (8) between which is contained the liquid active principle. Said needleless syringes are characterized in that they are capable of injecting a variable amount of liquid active principle (9) by adapting, through displacement of the downstream plug-piston (8) in the tube (6) the volume included between the two plug-pistons (7,8) to the amount of active principle (9) to be injected.Type: ApplicationFiled: February 29, 2008Publication date: June 26, 2008Applicant: CROSSJECTInventors: Patrick Alexandre, Bernard Brouquieres, Denis Roller
-
Patent number: 7357780Abstract: The technical field of the invention is that of pre-filled and disposable needleless syringes, used for intradermal, subcutaneous and intramuscular injections of liquid active principle for therapeutic use in human and veterinary medicine. The inventive syringes (1) are mainly characterized in that they function with a pyrotechnic charge (6) consisting of a mixture of powder with high burning rate and a powder with low burning rate. Indeed, the combustion of the powder with a high burning rate enables to communicate instantly, through a piston (3), a very high speed to the active principle (4), whereas the combustion of the powder with a low burning rate enables to maintain a threshold pressure level to proceed with the injection, so as to ensure that the active principle (4) penetrates through the skin. Thus, the injection is properly and homogeneously without any loss of active liquid (4).Type: GrantFiled: May 24, 2004Date of Patent: April 15, 2008Assignee: CrossjectInventors: Patrick Alexandre, Patrick Cognot, Joel Lafforgue, Denis Roller