Patents by Inventor Patrick Charnay

Patrick Charnay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEOTIDE SEQUENCE COMPRISING THE GENOME OF HEPATITIS B VIRUS, NUCLEOTIDE SEQUENCE CODING THE SURFACE ANTIGEN OF THE HEPATITIS B VIRUS, VECTORS CONTAINING THE NUCLEOTIDE SEQUENCES, PROCESS FOR THE PREPARATION THEREOF, AND ANTIGEN OBTAINED THEREBY
    Patent number: 6416996
    Abstract: A process produces DNA corresponding to that of the DNA of the virus of B hepatitis. It comprises cloning in bacteria the latter DNA, previously repaired by means of the corresponding precursor nucleotides in the presence of a polymerase. Vectors contain the cloned DNA in their genomes. The cloned DNA is useful as a probe for detecting the presence of the virus of B hepatitis in biological samples, particularly blood or plasma. Its expression in bacteria provides a hybrid protein containing a protein fragment having vaccinating properties against hepatitis B. Nucleic acid of reduced size and a vector containing the nucleotide sequence of which DNA codes an immunogenic peptide sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 9A.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 9, 2002
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Pierre Tiollais, Alex Fritsch, Christine Pourcel, Francois Galibert, Patrick Charnay
  • Process for the production of DNA comprising the genome of the hepatitis B virus and vector including it
    Patent number: 6225458
    Abstract: The invention relates to a process for producing DNA corresponding to that of the DNA of the virus of B hepatitis. It comprises cloning in bacteria the latter DNA, previously repaired by means of the corresponding precursor nucleotides in the presence of a polymerase. The invention also relates to vectors containing said cloned DNA in their genomes. The cloned DNA is useful as a probe for detecting the presence of the virus of B hepatitis in biological samples, particularly blood or plasma. Its expression in bacteria provides a hybrid protein containing a protein fragment having vaccinating properties against hepatitis B.
    Type: Grant
    Filed: November 23, 1994
    Date of Patent: May 1, 2001
    Assignees: Institut Pasteur, Institut National de la Santa et de la Recherche Medicale
    Inventors: Pierre Tiollais, Alex Fritsch, Christine Pourcel, Patrick Charnay
  • Nucleotide sequence comprising the genome of hepatitis B virus, nucleotide sequence coding the surface antigen of the hepatitis B virus, vectors containing the nucleotide sequences, process for the preparation thereof, and antigen obtained thereby
    Patent number: 6096879
    Abstract: A process produces DNA corresponding to that of the DNA of the virus of B hepatitis. It comprises cloning in bacteria the latter DNA, previously repaired by means of the corresponding precursor nucleotides in the presence of a polymerase. Vectors contain the cloned DNA in their genomes. The cloned DNA is useful as a probe for detecting the presence of the virus of B hepatitis in biological samples, particularly blood or plasma. Its expression in bacteria provides a hybrid protein containing a protein fragment having vaccinating properties against hepatitis B. Nucleic acid of reduced size and a vector containing the nucleotide sequence of which DNA codes an immunogenic peptide sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 9A.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: August 1, 2000
    Assignee: Institut Pasteur
    Inventors: Pierre Tiollais, Francis Galibert, Patrick Charnay
  • Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby
    Patent number: 4428941
    Abstract: Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 3A. Application to the production by cloning in a bacterium of an immunogenic protein immunizing against hepatitis B, or application to the obtention of probes for the diagnosis of the presence of Dane particles in a serum.
    Type: Grant
    Filed: April 30, 1981
    Date of Patent: January 31, 1984
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Francis Galibert, Pierre Tiollais, Patrick Charnay
  • Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby
    Patent number: RE34705
    Abstract: Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 3A. Application to the production by cloning in a bacterium of an immunogenic protein immunizing against hepatitis B, or application to the obtention of probes for the diagnosis of the presence of Dane particles in a serum.
    Type: Grant
    Filed: January 14, 1991
    Date of Patent: August 23, 1994
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Francis Galibert, Pierre Tiollais, Patrick Charnay