Patents by Inventor Patrick Leonard

Patrick Leonard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12214858
    Abstract: Removable covers and methods for covering emergency exit hatches are provided. An exemplary method includes removing the emergency exit enclosure from a hatch in a wall; pushing a removable cover from an interior of the wall into the hatch; and securing the removable cover in the hatch from the interior of the wall.
    Type: Grant
    Filed: February 22, 2023
    Date of Patent: February 4, 2025
    Assignee: GULFSTREAM AEROSPACE CORPORATION
    Inventors: Patrick Leonard, Caleb Wright, Caroline Culjak, Matthew Sandusky, Omar Khan
  • Patent number: 12144855
    Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized in the form of lyospheres of carrier protein and lyospheres of the one or more polysaccharides. A predetermined amount of carrier protein lyospheres and activated polysaccharide lyospheres are mixed together and the mixture reconstituted in an organic solvent to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: November 19, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
  • Patent number: 12128256
    Abstract: Methods for reducing electromagnetic interference arising from use of multiple ultrasound transducers in an array, particularly inside a human body that is inside a magnetic resonance imaging device. Electrical signals driving the transducers are offset in phase with respect to one another so as to achieve maximum offset of electrical and magnetic fields arising from such signals and transducers. Phase offsets are dynamically adjusted to respond to changes in driving amplitudes and frequencies so as to maintain optimal reduction of electromagnetic interference.
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: October 29, 2024
    Assignee: Profound Medical Inc.
    Inventors: Ron Kurtz, Patrick Leonard, Xiaoyu Zhang
  • Patent number: 12111203
    Abstract: An aircraft lifting assembly includes a jack, a load cell, and a jack adapter. The jack includes an extendable arm having a distal end portion for exerting a force to lift an object. The distal end portion defines a cavity. The jack adapter couples the extendable arm to the load cell and includes a base portion, a cradle portion, and a projection. The base portion defines a jack arm support surface and a load cell support surface. The jack arm support surface opposes the distal end portion of the extendable arm and the load cell support surface opposes the load cell. The cradle portion extends from the base portion to circumscribe a portion of the load cell to secure the jack adapter to the load cell. The projection extends from the base portion into the cavity to secure the jack adapter to the extendable arm of the jack.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: October 8, 2024
    Assignee: GULFSTREAM AEROSPACE CORPORATION
    Inventors: Patrick Leonard, Frank McDonough, Matthew Hansen, Paul Ashburn
  • Publication number: 20240278897
    Abstract: Removable covers and methods for covering emergency exit hatches are provided. An exemplary method includes removing the emergency exit enclosure from a hatch in a wall; pushing a removable cover from an interior of the wall into the hatch; and securing the removable cover in the hatch from the interior of the wall.
    Type: Application
    Filed: February 22, 2023
    Publication date: August 22, 2024
    Applicant: Gulfstream Aerospace Corporation
    Inventors: Patrick Leonard, Caleb Wright, Caroline Culjak, Matthew Sandusky, Omar Khan
  • Publication number: 20240261384
    Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized, the separately lyophilized polysaccharides and carrier protein are separately reconstituted in an organic solvent, and the reconstituted polysaccharide and carrier protein are then combined together by Tee-mixing and conjugated together to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.
    Type: Application
    Filed: April 17, 2024
    Publication date: August 8, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
  • Patent number: 11992521
    Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized, the separately lyophilized polysaccharides and carrier protein are separately reconstituted in an organic solvent, and the reconstituted polysaccharide and carrier protein are then combined together by Tee-mixing and conjugated together to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: May 28, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
  • Patent number: 11896656
    Abstract: A method is described for reconstituting lyophilized mutant diphtheria toxin in dimethyl sulfoxide for use in producing pneumococcal capsular polysaccharide mutant diphtheria toxin conjugates.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: February 13, 2024
    Assignee: MERCK SHARP & DOHME LLC
    Inventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
  • Publication number: 20240003655
    Abstract: A grip for a firearm comprised of an outer layer formed of thermoplastic vulcanite, an intermediate layer having a higher surface energy than the thermoplastic vulcanite, and an inner layer of pressure sensitive adhesive.
    Type: Application
    Filed: September 17, 2023
    Publication date: January 4, 2024
    Inventor: Patrick Leonard Hogue
  • Publication number: 20230414974
    Abstract: Methods for reducing electromagnetic interference arising from use of multiple ultrasound transducers in an array, particularly inside a human body that is inside a magnetic resonance imaging device. Electrical signals driving the transducers are offset in phase with respect to one another so as to achieve maximum offset of electrical and magnetic fields arising from such signals and transducers. Phase offsets are dynamically adjusted to respond to changes in driving amplitudes and frequencies so as to maintain optimal reduction of electromagnetic interference.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Inventors: Ron Kurtz, Patrick Leonard, Xiaoyu Zhang
  • Publication number: 20230414648
    Abstract: Compositions and methods for treating myotonic dystrophy type 1 (DM1) with SluCas9 and SaCas9 are encompassed.
    Type: Application
    Filed: November 5, 2021
    Publication date: December 28, 2023
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: John Patrick Leonard, Zachary Michael Detwiler, Peter Thomas Hallock, Eric Gunnar Anderson
  • Patent number: 11819713
    Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.
    Type: Grant
    Filed: November 15, 2022
    Date of Patent: November 21, 2023
    Assignee: Profound Medical Inc.
    Inventors: Levant Tinaz, Patrick Leonard, Xiaoyu Zhang, Ron Kurtz, Mathieu Allard
  • Patent number: 11814188
    Abstract: A fuel drain engagement tool and a method for draining fuel from a fuel tank are provided. In one example, a fuel drain engagement tool includes a housing. An engagement mechanism is coupled with the housing and extending upward therefrom. The engagement mechanism is configured to engage a fuel drain valve and to move between a contracted state and an expanded state. A compression applicator is coupled with the housing and is positioned to engage the engagement mechanism when the compression applicator is compressed to apply a force to the engagement mechanism that causes the engagement mechanism to move from the expanded state to the contracted state.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: November 14, 2023
    Inventors: Jeffery Barnes, Patrick Leonard, John Hume
  • Patent number: 11806554
    Abstract: Methods for reducing electromagnetic interference arising from use of multiple ultrasound transducers in an array, particularly inside a human body that is inside a magnetic resonance imaging device. Electrical signals driving the transducers are offset in phase with respect to one another so as to achieve maximum offset of electrical and magnetic fields arising from such signals and transducers. Phase offsets are dynamically adjusted to respond to changes in driving amplitudes and frequencies so as to maintain optimal reduction of electromagnetic interference.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: November 7, 2023
    Assignee: Profound Medical Inc.
    Inventors: Ron Kurtz, Patrick Leonard, Xiaoyu Zhang
  • Patent number: 11796283
    Abstract: A grip for a firearm comprised of an outer layer formed of thermoplastic vulcanite, an intermediate layer having a higher surface energy than the thermoplastic vulcanite, and an inner layer of pressure sensitive adhesive.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: October 24, 2023
    Inventor: Patrick Leonard Hogue
  • Publication number: 20230159157
    Abstract: A tool for adjusting an orientation of a nose landing gear of an aircraft is disclosed herein. The nose landing gear has an axle to which a wheel is mounted. The axle has an opening extending therethrough. The opening is defined by an inner surface of the axle. The tool includes, but is not limited to, a unitary member having a handle portion at a first end of the unitary member and an axle-engaging portion at a second end of the unitary member. The handle portion is configured for engagement with a hand of an operator. The axle-engaging portion is configured to be inserted into the opening and to engage with the inner surface.
    Type: Application
    Filed: November 22, 2021
    Publication date: May 25, 2023
    Applicant: Gulfstream Aerospace Corporation
    Inventors: Patrick Leonard, Caleb Wright, Adam Crouch, Spencer Waters, James Crago
  • Patent number: 11643968
    Abstract: An air intake system for an aircraft, which is switchable between a performance mode and a filtered mode, includes a duct forming filtered air inlet slits. The air intake system also includes interconnected gills adjacent to the filtered air inlet slits. The gills are movable between various gill positions including a closed position substantially covering the filtered air inlet slits and an open position substantially exposing the filtered air inlet slits. The air intake system also includes an actuator configured to move the gills into the closed position in the performance mode and the open position in the filtered mode.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: May 9, 2023
    Assignee: Textron Innovations Inc.
    Inventors: Bruce Bennett Bacon, Kristine Joyce Lazo, Shawn Patrick Leonard, Jr.
  • Publication number: 20230077640
    Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized, the separately lyophilized polysaccharides and carrier protein are separately reconstituted in an organic solvent, and the reconstituted polysaccharide and carrier protein are then combined together by Tee-mixing and conjugated together to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.
    Type: Application
    Filed: October 25, 2022
    Publication date: March 16, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
  • Publication number: 20230072545
    Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.
    Type: Application
    Filed: November 15, 2022
    Publication date: March 9, 2023
    Inventors: Levant Tinaz, Patrick Leonard, Xiaoyu Zhang, Ron Kurtz, Mathieu Allard
  • Patent number: 11547876
    Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: January 10, 2023
    Assignee: Profound Medical Inc.
    Inventors: Levant Tinaz, Patrick Leonard, Xiaoyu Zhang, Ron Kurtz, Mathieu Allard