Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.

Abstract: A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.

Abstract: An air intake system for an aircraft, which is switchable between a performance mode and a filtered mode, includes a duct forming filtered air inlet slits. The air intake system also includes interconnected gills adjacent to the filtered air inlet slits. The gills are movable between various gill positions including a closed position substantially covering the filtered air inlet slits and an open position substantially exposing the filtered air inlet slits. The air intake system also includes an actuator configured to move the gills into the closed position in the performance mode and the open position in the filtered mode.

Abstract: Temperature uncertainty maps are calculated based on a rolling window of temperature maps, which is updated as new temperature maps are generated. The rolling window mitigates the effect of transient motion during a thermal therapy procedure. A clinician or an automated control system can then update a portion of an anatomical boundary or the thermal therapy applicator center based on the temperature uncertainty map.

Abstract: Cradle assemblies for supporting a door for uninstalling and/or installing the door to a fuselage of an aircraft, and arrangements and methods for the same are provided. In one example, a cradle assembly includes a first contoured board and a second contoured board that is spaced apart from the first contoured board. The first and second contoured boards are cooperatively configured to support outer sections of a first door. A third contoured board is configured to be selectively positioned adjacent to and extending higher than the first contoured board to support a first outer section of a second door that has a different outer shape than the first door. The third contoured board is contoured to substantially match the first outer section of the second door. The cradle assembly is configured to be positioned proximate to the fuselage.

Abstract: An aircraft lifting assembly includes a jack, a load cell, and a jack adapter. The jack includes an extendable arm having a distal end portion for exerting a force to lift an object. The distal end portion defines a cavity. The jack adapter couples the extendable arm to the load cell and includes a base portion, a cradle portion, and a projection. The base portion defines a jack arm support surface and a load cell support surface. The jack arm support surface opposes the distal end portion of the extendable arm and the load cell support surface opposes the load cell. The cradle portion extends from the base portion to circumscribe a portion of the load cell to secure the jack adapter to the load cell. The projection extends from the base portion into the cavity to secure the jack adapter to the extendable arm of the jack.

Abstract: Compositions and methods for treating excising trinucleotide repeats, as well as for treating diseases and disorders associated with trinucleotide repeats are encompassed.

Abstract: A jack pad device adapted to transfer loads between an aircraft and a jack device for jacking the aircraft, and a method for jacking an aircraft are provided. In one non-limiting example, the jack pad device includes a jack pad body. A jack engagement portion extends from the jack pad body and is configured to engage the jack device. A first coupler is attached to the jack pad body and is configured to couple to the aircraft to hold the jack pad device to the aircraft.

Abstract: A leveling device is disclosed herein. The leveling device includes a body having a body having front surface, bottom surface, side surface and a rear mounting support, the side surface having an aperture configurated to receive a spirt level and a front surface having an aperture therein for viewing the sprit level in the body and the rear mounting support having a first mounting surface configured to be at an angle relative to a plane of the bottom surface, and a second mounting surface orthogonal to the first mounting surface, each of the first and second mounting surfaces having at least one aperture formed therein to receive a magnetic coupling element, whereby, the body containing the sprit level may be magnetically coupled to a vehicle to indicate whether the vehicle remains level during a jacking operation.

Abstract: A leveling device is disclosed herein. The leveling device includes a body having a body having front surface, bottom surface, side surface and a rear mounting support, the side surface having an aperture configurated to receive a spirt level and a front surface having an aperture therein for viewing the sprit level in the body and the rear mounting support having a first mounting surface configured to be at an angle relative to a plane of the bottom surface, and a second mounting surface orthogonal to the first mounting surface, each of the first and second mounting surfaces having at least one aperture formed therein to receive a magnetic coupling element, whereby, the body containing the sprit level may be magnetically coupled to a vehicle to indicate whether the vehicle remains level during a jacking operation.

Abstract: In one aspect, a method comprises: receiving data indicative of at least one phase image captured using a magnetic resonance imaging (MRI) device during delivery of thermal therapy by a thermal therapy applicator to a target volume within a patient's body; and processing said at least one phase image; wherein said processing said at least one phase image comprises: applying a first mask; applying phase unwrap; and applying a second mask.

Abstract: A grip for a firearm comprised of an outer layer formed of thermoplastic vulcanite, an intermediate layer having a higher surface energy than the thermoplastic vulcanite, and an inner layer of pressure sensitive adhesive.

Abstract: A method is described for reconstituting lyophilized mutant diphtheria toxin in dimethyl sulfoxide for use in producing pneumococcal capsular polysaccharide mutant diphtheria toxin conjugates.

Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized, the separately lyophilized polysaccharides and carrier protein are separately reconstituted in an organic solvent, and the reconstituted polysaccharide and carrier protein are then combined together by Tee-mixing and conjugated together to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.

Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized in the form of lyospheres of carrier protein and lyospheres of the one or more polysaccharides. A predetermined amount of carrier protein lyospheres and activated polysaccharide lyospheres are mixed together and the mixture reconstituted in an organic solvent to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.

Abstract: A jack pad holding devices for supporting a jack pad to an aircraft, and a method for jacking an aircraft are provided. In one non-limiting example, the jack pad holding device includes a coupler housing configured for holding the jack pad. Coupling elements are coupled to the coupler housing and are configured to couple to the aircraft.

Abstract: Cradle assemblies for supporting a door for uninstalling and/or installing the door to a fuselage of an aircraft, and arrangements and methods for the same are provided. In one example, a cradle assembly includes a first contoured board and a second contoured board that is spaced apart from the first contoured board. The first and second contoured boards are cooperatively configured to support outer sections of a first door. A third contoured board is configured to be selectively positioned adjacent to and extending higher than the first contoured board to support a first outer section of a second door that has a different outer shape than the first door. The third contoured board is contoured to substantially match the first outer section of the second door. The cradle assembly is configured to be positioned proximate to the fuselage.

Abstract: A jack pad device adapted to transfer loads between an aircraft and a jack device for jacking the aircraft, and a method for jacking an aircraft are provided. In one non-limiting example, the jack pad device includes a jack pad body. A jack engagement portion extends from the jack pad body and is configured to engage the jack device. A first coupler is attached to the jack pad body and is configured to couple to the aircraft to hold the jack pad device to the aircraft.

Abstract: Cradle assemblies for supporting a door of an aircraft to facilitate servicing the door, and arrangements and methods for the same are provided. In one example, a cradle assembly includes a base and a cradle support subassembly pivotably coupled to the base. The cradle support subassembly is configured to support an outer section of the door.

Abstract: A fuel drain engagement tool and a method for draining fuel from a fuel tank are provided. In one example, a fuel drain engagement tool includes a housing. An engagement mechanism is coupled with the housing and extending upward therefrom. The engagement mechanism is configured to engage a fuel drain valve and to move between a contracted state and an expanded state. A compression applicator is coupled with the housing and is positioned to engage the engagement mechanism when the compression applicator is compressed to apply a force to the engagement mechanism that causes the engagement mechanism to move from the expanded state to the contracted state.