Patents by Inventor Patrick Louis

Patrick Louis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9695214
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: July 4, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20170081359
    Abstract: Methods and system for solid phase peptide synthesis are provided. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. New amino acid residues are added via a coupling reaction between an activated amino acid and an amino acid residue of the immobilized peptide. Amino acids may be activated using, e.g., a base and an activating agent. Certain inventive concepts, described herein, relate to methods and systems for the activation of amino acids. These systems and methods may allow for fewer side reactions and a higher yield compared to conventional activation techniques as well as the customization of the coupling reaction on a residue-by-residue basis without the need for costly and/or complex processes.
    Type: Application
    Filed: September 16, 2016
    Publication date: March 23, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: Dale Arlington Thomas, III, Alexander James Mijalis, Bradley L. Pentelute, Mark David Simon, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Patent number: 9501460
    Abstract: A system and machine-implemented method for detecting and processing invisible elements within a web page. A web page is accessed to detect one or more elements in the web page. One or more criteria for identifying web page elements, which are invisible when displayed, are obtained. The one or more criteria are applied to the one or more elements. Based on the applied criteria, a determination is made that one of the one or more elements is invisible. A notification of the invisible element is provided for display.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: November 22, 2016
    Assignee: Google Inc.
    Inventors: Dominic Pascal Battré, Andrew Swerdlow, Markus Heintz, Patrick Louis Maurice Nepper
  • Patent number: 9404172
    Abstract: A coating is described for an airfoil blade component. The coating comprises a cermet material and has, when applied to the rotor blade, a compressive residual stress greater than about 60 ksi. In another embodiment, the compressive residual stress of the coating is in the range of approximately 90-110 ksi.
    Type: Grant
    Filed: October 2, 2012
    Date of Patent: August 2, 2016
    Assignee: SIKORSKY AIRCRAFT CORPORATION
    Inventors: Patrick Louis Clavette, Jun Shi, Aaron T. Nardi
  • Patent number: 9390193
    Abstract: Embodiments of the invention include a system, computer-implemented method, and a computer-readable medium for delaying the storage of data. Data that manipulates website data is provided from a web server to a client device in response to a request for a webpage. Data is initially stored in a temporary memory storage. The temporary memory storage is associated with a browser and stores data before data is moved to a persistent memory storage. A notification is generated that indicates that data was received and is intended to be stored persistently or manipulate, access or rely on website data in the persistent memory storage. Depending on the response to the notification, the system determines how data in temporary memory storage will be processed and whether data can be stored in the persistent memory storage or manipulate, access and rely on website data in the persistent memory storage.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: July 12, 2016
    Assignee: GOOGLE INC.
    Inventors: Patrick Louis Maurice Nepper, Jochen Mathias Eisinger, Wieland Holfelder
  • Publication number: 20160181498
    Abstract: A thermoelectric metamaterial is provided, comprising a plurality of component materials selected from the group consisting of dielectrics, semiconductors, semimetals, and metals. The component materials are placed into contact with one another and arranged in a selected geometrical configuration adapted to achieve a thermal conductivity of the metamaterial that is different from the thermal conductivity of each of the component materials. Specifically, the component materials are arranged to affect an increase in the figure of merit and power conversion efficiency of the metamaterial.
    Type: Application
    Filed: March 14, 2014
    Publication date: June 23, 2016
    Applicant: LOYOLA UNIVERSITY NEW ORLEANS
    Inventor: Patrick Louis Garrity
  • Publication number: 20160130705
    Abstract: A method of applying a coating system to a substrate includes applying a first layer of a high hardness and high modulus of elasticity with an added metal to the substrate, applying a second layer of the high hardness and high modulus of elasticity in combination with the added metal to the first layer. A percent by volume of the added metal in the second layer is lower than the percent by volume of the added metal in the first layer. The method also includes applying two or more intermediate layers formed from an applied mixture of the high hardness, high modulus of elasticity material and a metal material between the first layer and the second layer.
    Type: Application
    Filed: January 19, 2016
    Publication date: May 12, 2016
    Inventors: Aaron T. Nardi, Tahany Ibrahim El-Wardany, Jun Shi, Patrick Louis Clavette, Xuemei Wang
  • Publication number: 20160102118
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Application
    Filed: September 14, 2015
    Publication date: April 14, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Patent number: 9273400
    Abstract: An erosion resistant coating for a substrate includes two or more coating layers affixed to the substrate having an increasing modulus of elasticity and hardness from an innermost layer of the coating adjacent to the substrate to an outermost layer of the coating furthest from the substrate. A method of applying a coating system to a substrate includes applying a first layer of a high hardness and high modulus of elasticity material combined with an added metal to the substrate. A second layer of the high hardness and high modulus of elasticity material combined with the added metal is applied to the first layer, resulting in a coating system wherein the second layer has a modulus of elasticity and hardness greater than the modulus of elasticity and hardness of the first layer.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: March 1, 2016
    Assignee: SIKORSKY AIRCRAFT CORPORATION
    Inventors: Aaron T. Nardi, Tahany Ibrahim El-Wardany, Jun Shi, Patrick Louis Clavette, Xuemei Wang
  • Publication number: 20160031931
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Application
    Filed: February 24, 2014
    Publication date: February 4, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Patent number: 9169287
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 27, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20150285387
    Abstract: Pressure control in fluidic systems is generally described. New trends in chemical synthesis involve the use of continuous reaction schemes, for example, in microfluidic and/or millifluidic devices. In many of these processes, it is often helpful to maintain controlled separation between two liquid phases and/or between a liquid phase and a gas phase. For example, in many processes, liquid-liquid and/or a gas-liquid separations are performed (e.g.
    Type: Application
    Filed: August 9, 2013
    Publication date: October 8, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Andrea Adamo, Alexander P. Clayton, Patrick Louis Heider, Nopphon Weeranoppanant, Klavs F. Jensen
  • Publication number: 20150200829
    Abstract: A method includes identifying one or more browsing sessions from a plurality of browsing activities, each of the one or more browsing sessions comprising browsing activities having a common theme, identifying a browser state of each of the one or more browsing sessions, generating a record representing the browser state of each of the one or more browsing sessions, wherein the record is associated with the common theme of the browsing activities comprising each of the one or more browsing sessions, storing the generated record representing the browser state of each of the one or more browsing sessions and retrieving the stored record when a current online activity has a theme that corresponds to the common theme of the at least one of the one or more browsing sessions.
    Type: Application
    Filed: March 14, 2013
    Publication date: July 16, 2015
    Inventors: Patrick Louis Dubroy, Patrick Louis Maurice Nepper, Bryan Christopher Horling
  • Publication number: 20150086083
    Abstract: A method for detecting a crack in a structural component includes receiving, with a processor, signals indicative of at least one image for a critical location in the structural component; determining, with the processor, at least one shape in the at least one image, the at least one shape being representative of a structure of the critical location; representing, with the processor, at least one region around the structure into a matrix; and applying, with the processor, image processing on the matrix to detect cracks in the at least one region of the structural component.
    Type: Application
    Filed: September 25, 2013
    Publication date: March 26, 2015
    Applicant: SIKORSKY AIRCRAFT CORPORATION
    Inventors: Zaffir A. Chaudhry, Alan Matthew Finn, Ziyou Xiong, Hongcheng Wang, Patrick Louis Clavette
  • Publication number: 20140366573
    Abstract: A heat exchange tube for a refrigerant-flooded evaporator includes a tube body and a plurality of channels for conveying a cooling medium therethrough located in the tube body. One or more outer wall textural elements are included at the outer wall of the tube body to improve thermal energy transfer between the cooling medium and a volume of boiling refrigerant. A method of forming a heat exchange tube for a refrigerant-flooded evaporator includes urging a billet into an extrusion section and forming the billet into two tube halves including an outer wall and an inner wall having a plurality of channel halves. A textural element is formed at one or more of the outer wall and the inner wall via one or more rotating dies, and the two tube halves are joined to form the heat exchange tube.
    Type: Application
    Filed: November 28, 2012
    Publication date: December 18, 2014
    Inventors: Patrick Louis Clavette, Satyam Bendapudi, Jefferi J. Covington
  • Patent number: 8852751
    Abstract: A wear resistant device includes a substrate of a first metallic material and a wear resistant layer disposed on a substrate. The wear resistant layer includes a matrix of a second, different metallic material, particulates dispersed throughout the matrix, and a boron material dispersed within a portion of the matrix.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: October 7, 2014
    Assignee: Hamilton Sundstrand Corporation
    Inventors: Blair A. Smith, Aaron T. Nardi, Kevin M. Rankin, Patrick Louis Clavette
  • Publication number: 20140275481
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20140093378
    Abstract: A coating is described for an airfoil blade component. The coating comprises a cermet material and has, when applied to the rotor blade, a compressive residual stress greater than about 60 ksi. In another embodiment, the compressive residual stress of the coating is in the range of approximately 90-110 ksi.
    Type: Application
    Filed: October 2, 2012
    Publication date: April 3, 2014
    Inventors: Patrick Louis Clavette, Jun Shi, Aaron T. Nardi
  • Publication number: 20140019518
    Abstract: Embodiments of the invention include a system, computer-implemented method, and a computer-readable medium for delaying the storage of data. Data that manipulates website data is provided from a web server to a client device in response to a request for a webpage. Data is initially stored in a temporary memory storage. The temporary memory storage is associated with a browser and stores data before data is moved to a persistent memory storage. A notification is generated that indicates that data was received and is intended to be stored persistently or manipulate, access or rely on website data in the persistent memory storage. Depending on the response to the notification, the system determines how data in temporary memory storage will be processed and whether data can be stored in the persistent memory storage or manipulate, access and rely on website data in the persistent memory storage.
    Type: Application
    Filed: July 16, 2012
    Publication date: January 16, 2014
    Applicant: Google Inc.
    Inventors: Patrick Louis Maurice NEPPER, Jochen Mathias EISINGER, Wieland HOLFELDER
  • Patent number: 8578036
    Abstract: A system and a computer-implemented method for processing a cookie description file are provided. A browser provides the cookie description file that includes meta-information associated with cookies that are associated with a domain. The meta-information includes cookie information specific to each cookie. The cookie description file is parsed and the meta-information associated with each cookie is extracted. The parsed meta-information is displayed in a user-readable format on a client device.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: November 5, 2013
    Assignee: Google Inc.
    Inventors: Wieland Holfelder, Dominic Battré, Michael Christopher West, Jochen Mathias Eisinger, Bernhard Bauer, Patrick Louis Maurice Nepper, Pamela Greene, Adam Barth