Patents by Inventor Patrick Michael

Patrick Michael has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210017229
    Abstract: It is provided a chemical compound according to general formula (1)
    Type: Application
    Filed: March 28, 2019
    Publication date: January 21, 2021
    Applicant: TECHNISCHE UNIVERSITÄT BERLIN
    Inventors: Roderich SUESSMUTH, Stefan GRAETZ, Iraj BEHROZ, Leonard VON ECKARDSTEIN, Patrick Michael DURKIN, John WESTON, Lieby ZBOROVSKY
  • Publication number: 20200407344
    Abstract: Provided herein are compounds of the Formula I: and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and malignant extracranial BRAF-associated tumors.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 31, 2020
    Applicant: Array BioPharma Inc.
    Inventors: Patrick Michael BARBOUR, Katie Keaton BROWN, Adam Wade COOK, Erik James HICKEN, Dean Russell KAHN, Ellen Ruth LAIRD, Andrew Terrance METCALF, David Austin MORENO, Bradley Jon NEWHOUSE, Spencer Phillip PAJK, Brett Joseph PRIGARO, Li REN, Eugene TARLTON
  • Patent number: 10858151
    Abstract: A storage container includes a body, a lid, and two handles. The body defines a compartment between first and second side walls of the body. The compartment is accessible along a top end of the body. The first and second side walls include respective cavities that are recessed from exterior surfaces of the side walls via rims that define perimeters of the cavities. The lid is connected to the top end of the body and encloses the compartment when in a closed position. The two handles are tethered to the body via cords, and are configured to nest within the cavities of the corresponding side walls when not grasped by a person. First and second ends of the handles are configured to engage opposing portions of the corresponding rim to retain the handle nested in the cavity via an interference fit.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: December 8, 2020
    Assignee: MUCKBOX, LLC
    Inventors: Daniel Campbell Schaefer, Patrick Michael Barron
  • Publication number: 20200375891
    Abstract: The present disclosure is directed to a composite implant for the sustained release of a therapeutic agent from a hydrogel matrix. The hydrogel matrix may be a cross-linked bioerodible polyethylene glycol (PEG) hydrogel with a therapeutic complex dispersed within the cross-linked bioerodible PEG hydrogel. The therapeutic complex may include a therapeutic agent in association with either a fatty acid or fatty alcohol and/or any other excipients, peptides, or nucleic acids. The composite implant is configured to be delivered to or implanted into an eye of a subject or patient. The composite implant may comprise a rod shape. The composite implant may be used treat ocular disease in a subject or patient. Ocular diseases may be selected from at least one of neovascular age related macular degeneration (AMD), diabetic macular edema, or macular edema following retinal vein occlusion.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Inventors: Patrick Michael Hughes, David Bardin, Ina Mustafaj, Harold A. Heitzmann
  • Publication number: 20200375889
    Abstract: The present disclosure provides compositions that enable sustained release of a small molecule tyrosine kinase inhibitor, such as axitinib from a bioerodible polyester polymer implant for the treatment of disease. The composition is especially suitable for treating ophthalmic indications, such as neovascular age related macular degeneration and diabetic macular edema, by intravitreal injection of the implant. The implant is designed to be pre-loaded into a small diameter needle and injected via self-sealing scleral needle penetration at the pars plana. Small molecule tyrosine kinase inhibitors may be released from the implants over a period of one week to three years.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Inventors: Patrick Michael Hughes, James Shiah, Jack Xie, Jia-Ying Yang
  • Publication number: 20200361308
    Abstract: A ventilation device for ventilating a motor vehicle tank. The ventilation device includes a filler pipe, a ventilation line, a degassing line, and a guide arc member. The ventilation line is to be fluidically connected at a first ventilation line end to the motor vehicle tank, and at a second ventilation line end to the filler pipe via a ventilation inlet. The degassing line is to be fluidically connected at a first degassing line end to the filler pipe via a degassing outlet. The guide arc member is arranged in the filler pipe to define a guide path for incoming vapor passing through the ventilation inlet into the filler pipe. The guide arc member is to facilitate flow of the incoming vapor between an inner wall of the filler pipe and the guide arc member along a periphery of the filler pipe along a periphery of the filler pipe such that a gaseous component of the incoming vapor escapes through the degassing outlet and a liquid component of the incoming vapor flows off through the filler pipe.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 19, 2020
    Inventors: Patrick Michael WIEDNER, Dominik STEINMANN, Karl-Heinz KULMER
  • Publication number: 20200360839
    Abstract: A venting device for venting a motor vehicle tank that includes a filling pipe, a venting line, a degassing line, and a connection nipple. The venting line is for fluidic connection at a first venting line end to the motor vehicle tank, and at a second venting line end opposite the first venting line end to the filling pipe via a venting inlet. The degassing line is for fluidic connection at a first degassing line end to the filling pipe via a degassing outlet, and at a second degassing line end opposite the first degassing line end to a liquid separator. The connection nipple is arranged on the filling pipe upon which the venting inlet and the degassing outlet are constructed.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 19, 2020
    Inventors: Patrick Michael WIEDNER, Dominik STEINMANN, Karl-Heinz KULMER
  • Publication number: 20200356927
    Abstract: This disclosure describes a transportation matching system that utilizes one or more balancer models to generate an electronic communication distribution strategy based on relative impacts of provider-specific and requester-specific levers over a target time horizon. The disclosed systems utilize the balancer models to generate predictive functions for providers and requesters to determine lever content to distribute (e.g., within electronic communications) to providers and/or requesters to efficiently and/or effectively produce acquisition and/or engagement for a target time horizon. Based on the predictive functions, the disclosed systems generate an electronic communication distribution strategy to provide (or cause to be provided) electronic communications to providers and requesters to efficiently and effectively increase or decrease acquisition and/or engagement.
    Type: Application
    Filed: May 6, 2019
    Publication date: November 12, 2020
    Inventors: Jose Alberto Abelenda, Alkan William Borges, Anna Grace Campanelli, Carolyn Jones Conway, Ismail Can Coskuner, Jared Matthew Gabor, Alok Gupta, Langfei He, Robert Bryant Kaspar, Ivan Kirigin, Patrick Michael McGrath, Quang Huy Nguyen, Ajay Pankaj Sampat, Karthik Subramaniam, Muhammad Usman, Su Wang
  • Publication number: 20200354715
    Abstract: A system and method for automated single cell capture and processing is described, where the system includes a deck supporting and positioning a set of sample processing elements; a gantry for actuating tools for interactions with the set of sample processing elements supported by the deck; and a base supporting various processing subsystems and a control subsystems in communication with the processing subsystems. The system can automatically execute workflows associated with single cell processing, including mRNA capture, cDNA synthesis, protein-associated assays, and library preparation, for next generation sequencing.
    Type: Application
    Filed: May 5, 2020
    Publication date: November 12, 2020
    Inventors: Kalyan Handique, Austin Payne, Sida Wang, Patrick Michael Tegels, Will Koederitz, Daniel Genord, Grey Parker, Brian Boniface, Katlyn Curtin Mehne, Alec William Hitchiner
  • Publication number: 20200353472
    Abstract: A system and method for automated single cell capture and processing is described, where the system includes a deck supporting and positioning a set of sample processing elements; a gantry for actuating tools for interactions with the set of sample processing elements supported by the deck; and a base supporting various processing subsystems and a control subsystems in communication with the processing subsystems. The system can automatically execute workflows associated with single cell processing, including mRNA capture, cDNA synthesis, protein-associated assays, and library preparation, for next generation sequencing.
    Type: Application
    Filed: May 5, 2020
    Publication date: November 12, 2020
    Inventors: Kalyan Handique, Austin Payne, Sida Wang, Patrick Michael Tegels, Will Koederitz, Daniel Genord, Grey Parker, Brian Boniface, Katlyn Curtin Mehne, Alec William Hitchiner
  • Patent number: 10821518
    Abstract: A method and apparatus for fabricating an object. The method and apparatus entail applying a pulsed laser energy to a first quantity of a powder material on a substrate so as to fuse particles of the powder material into a first layer on the substrate, and then forming at least one additional layer on the first layer by applying a pulsed laser energy to at least a second quantity of the powder material on the first layer so as to fuse particles of the powder material into the at least one additional layer on the first layer. The pulsed laser energy is applied in a controlled manner such that solidification dynamics of the first and second quantities of the powder material are altered to promote at least one microstructural characteristic of the first and additional layer.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: November 3, 2020
    Assignee: General Electric Company
    Inventors: Patrick Michael Kenney, Dustin Eugene Lindley
  • Patent number: 10814955
    Abstract: An aircraft includes a boundary layer ingestion fan defining a centerline and including a plurality of fan blades rotatable about the centerline. The aircraft also includes a fuselage extending between a forward end and an aft end along a longitudinal direction, the boundary layer ingestion fan positioned within the fuselage at the aft end of the fuselage, the fuselage defining an inlet upstream of the boundary layer ingestion fan extending at least about 180 degrees around the centerline of the boundary layer ingestion fan, the fuselage further defining an exhaust downstream of the boundary layer ingestion fan.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: October 27, 2020
    Assignee: General Electric Company
    Inventors: Jixian Yao, Nikolai N. Pastouchenko, Patrick John Lonneman, Patrick Michael Marrinan, Richard David Cedar
  • Publication number: 20200331622
    Abstract: A propulsion system for an aircraft having an aft end is provided herein. The propulsion system can include an electric propulsion engine defining a central axis. The electric propulsion engine can include an electric motor, a fan rotatable about the central axis of the electric propulsion engine by the electric motor, a bearing supporting rotation of the fan, and a thermal management system. The thermal management system can include a lubrication oil circulation assembly for providing the bearing with lubrication oil. The lubrication oil circulation assembly can be driven independently of a shaft of the electric propulsion engine.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 22, 2020
    Inventors: Daniel Alan Niergarth, Randy M. Vondrell, Brandon Wayne Miller, Patrick Michael Marrinan, Lawrence Chih-hui Cheung, Nikolai N. Pastouchenko
  • Patent number: 10800539
    Abstract: A propulsion system for an aircraft includes a gas turbine engine and an electric propulsion engine defining a central axis. The electric propulsion engine includes an electric motor and a fan rotatable about the central axis of the electric propulsion engine by the electric motor. The electric propulsion engine additionally includes a bearing supporting rotation of the fan and a thermal management system including a thermal fluid circulation assembly. The thermal fluid circulation assembly is in thermal communication with at least one of the electric motor or the bearing and is further in thermal communication with a heat exchanger of a thermal management system of the gas turbine engine.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: October 13, 2020
    Assignee: General Electric Company
    Inventors: Daniel Alan Niergarth, Randy M. Vondrell, Brandon Wayne Miller, Patrick Michael Marrinan, Lawrence Chih-hui Cheung, Nikolai N. Pastouchenko
  • Patent number: 10787378
    Abstract: Spirally wound electric double layer capacitor devices are generally disclosed. In some embodiments, the spirally wound electric double layer capacitor device is configured so that fluid being treated flows in an axial direction through the device.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: September 29, 2020
    Assignee: Atlantis Technologies
    Inventors: Neil Austin, Lukas Buell, Patrick Michael Curran, Ryan Gilmore, John Ramos, Philip Reeder, Jacob Silverman
  • Publication number: 20200301950
    Abstract: A method and system for providing keyword suggestions to a user of a document during use of the document, the keyword suggestions being made to enable selection of the keywords as tags for the document. The method includes examining contents of a document, identifying a keyword related to the document based at least in part on the contents of the document, displaying the keyword on a user interface element relating to the document to enable a user to choose to add the keyword as a tag associated with the document, receiving an input indicating a user's approval of the keyword, and upon receiving the input, associating the keyword with the document as a tag.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 24, 2020
    Applicant: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Theo LORRAIN-HALE, Patrick Michael GAN
  • Patent number: D907254
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 5, 2021
    Assignee: CPG International LLC
    Inventors: Patrick Michael Barnds, Jason Andrew Davoll
  • Patent number: D907255
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 5, 2021
    Assignee: CPG International LLC
    Inventors: Patrick Michael Barnds, Jason Andrew Davoll
  • Patent number: D907256
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 5, 2021
    Assignee: CPG International LLC
    Inventors: Patrick Michael Barnds, Jason Andrew Davoll
  • Patent number: D907811
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 12, 2021
    Assignee: CPG International LLC
    Inventors: Patrick Michael Barnds, Jason Andrew Davoll