Abstract: Krypton and/or xenon is separated crudely from a mixture comprising oxygen and at least one rare gas selected from the group consisting of krypton and xenon in a process comprising feeding said mixture or a mixture derived therefrom to a rare gas recovery system and separating said mixture feed in said rare gas recovery system into rare gas-lean gaseous oxygen (“GOX”) and rare gas-enriched product. The process is characterized in that at least about 50 mol % of said mixture is fed to the rare gas recovery system in the gaseous phase provided that, when said mixture feed is separated by selective adsorption, the concentration of xenon in the mixture feed is no greater than 50 times the concentration of xenon in air. One advantage of a preferred embodiment of the present invention is that it can easily be retrofitted to existing pumped LOX cycle ASUs.

Abstract: Krypton and/or xenon is separated crudely from a mixture comprising oxygen and at least one rare gas selected from the group consisting of krypton and xenon in a process comprising feeding said mixture or a mixture derived therefrom to a rare gas recovery system and separating said mixture feed in said rare gas recovery system into rare gas-lean gaseous oxygen (“GOX”) and rare gas-enriched product. The process is characterized in that at least about 50 mol % of said mixture is fed to the rare gas recovery system in the gaseous phase provided that, when said mixture feed is separated by selective adsorption, the concentration of xenon in the mixture feed is no greater than 50 times the concentration of xenon in air. One advantage of a preferred embodiment of the present invention is that it can easily be retrofitted to existing pumped LOX cycle ASUs.

Abstract: An improved method for fabricating a window frame/window piece assembly is disclosed in this application. A window frame having an opening in its inner portion is provided. According to one aspect, the window frame can be formed from a unitary piece of sheet metal. A transparent piece is attached to the inner portion of the window frame through a molding process. According to one embodiment, the window frame is placed within a mold such that the inner portion of the window frame projects into an inner cavity inside the mold. After the mold has been closed, a transparent material is injected into the inner cavity so that it bonds with the inner portion of the window frame. After the bond of between the transparent material and the window frame is set, the window frame/window piece assembly is removed from the mold. According to another embodiment, a plurality of window frames may be loaded into a single mold so that a plurality of window frame/window piece assemblies can be fabricated in a single batch.

Abstract: The present invention relates to the identification, isolation and purification of the catalytic domain of the human effector checkpoint protein kinase (hChk1). A 1.7Å crystal structure of the hChk1 kinase domain in the active conformation is reported herein. The kinase domain of hChk1 and its associated crystal structure is described for use in the discovery, identification and characterization of inhibitors of hChk1. This structure provides a three-dimensional description of the binding site of the hChk1 for structure-based design of small molecule inhibitors thereof as therapeutic agents. Inhibitors of hChk1 find utility in the treatment of hyperproliferative disorders such as HIV and cancer.

Abstract: The present invention relates to the identification, isolation and purification of the catalytic domain of the human effector checkpoint protein kinase (hChk1). A 1.7 Å crystal structure of the hChk1 kinase domain in the active conformation is reported herein. The kinase domain of hChk1 and its associated crystal structure is described for use in the discovery, identification and characterization of inhibitors of hChk1. This structure provides a three-dimensional description of the binding site of the hChk1 for structure-based design of small molecule inhibitors thereof as therapeutic agents. Inhibitors of hChk1 find utility in the treatment of hyperproliferative disorders such as HIV and cancer.

Abstract: Liquid oxygen (“LOX”) product and a krypton- and xenon-enriched liquid product is produced from the cryogenic separation of air using a cryogenic distillation system. The process comprises separating feed air in the main distillation system into nitrogen-rich overhead vapor and said krypton- and xenon-enriched liquid product. At least a portion of said krypton- and xenon-enriched liquid product is removed from the main distillation system for further distillation, to produce at least one krypton- and/or xenon-rich product. Xenon-lean liquid is fed to the first additional distillation column and separated into oxygen-rich overhead vapor and said LOX product having a concentration of xenon less than that in said feed air. The xenon-lean liquid is usually also lean in krypton.

Abstract: An improved window frame and window piece for a micromirror assembly is disclosed herein. The window frame includes a stress-relieving contour positioned in the middle of the frame that can absorb the mechanical stresses applied to the window frame from the ceramic base and from the window piece. The window frame may be comprised of a single piece of sheet metal that has been stamped to include a stress-relieving contour. The stress-relieving contour may be comprised of a variety of shapes, including a “U” shape, an inverted “U” shape, a curved step shape, or other combinations thereof.

Abstract: A process for producing a nitrogen-enriched vapor product from a supply of a nitrogen-rich liquid uses a purifying device and a distillation column having a distillation zone. The process includes the steps of: feeding at least a portion of the supply of the nitrogen-rich liquid to the distillation zone at a first location; feeding a stream of a gas containing nitrogen and at least one contaminant to the purifying device, wherein the gas is cooled by a cryogenic liquid whereby at least a portion of the at least one contaminant condenses, solidifies, or dissolves; eventually feeding at least a portion of the cool gas from the purifying device to the distillation zone at a second location below the first location; withdrawing a stream of the nitrogen-enriched vapor product from the distillation zone; and withdrawing a stream of an oxygen-enriched liquid from the distillation zone.

Abstract: The invention provides compositions and methods for the detection and quantification of A. phagocytophila (formerly known as Ehrlichia equi) antibodies and antibody fragments.

Abstract: The invention provides compositions and methods for the detection and quantification of Ehrlichia equi antibodies and antibody fragments.

Abstract: The invention provides devices and methods for detecting the presence or absence of Dirofilaria immitis, Borrelia burgdorferi, and Ehrlichia canis in a sample.

Abstract: The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments.

Abstract: The invention relates to compositions and methods for enhancing bone healing, bone formation and wound healing. More specifically, it relates to the use of cyclooxygenase 2 (COX-2) following bone fracture, orthopaedic procedure or wound infliction to enhance healing.

Abstract: A method of synchronizing digitized audio information and digitized picture information establishes a reference time base based on timecodes included with the audio and picture information. The reference time base may be used to synchronize output between a digitized source and one which may be digitized or undigitized.

Abstract: A method and system for curing reactive material. The system includes an inlet port adapted to receive radiation from a source, at least one emitter port, and transmission means operatively coupling the inlet port to each emitter port. The transmission means is adapted to conduct radiation from the inlet port to the emitter ports. Preferably, the emitter port is configured in a shape approximating the surface area of the curable material. The method includes the steps of providing a curing system made in accordance with the present invention, positioning the reactive material proximate the emitter port, and directing radiation within the absorption spectrum of the reactive material into the inlet port until the reactive material is sufficiently cured.

Abstract: A method and system for curing reactive material. The system includes an inlet port adapted to receive radiation from a source, a plurality of emitter ports and transmission means operatively coupling the inlet port to each emitter port. The transmission means is adapted to conduct radiation from the inlet port to the emitter ports and preferably includes a plurality of optical fibre strands. Additionally, the system also preferably includes a housing defining a substantially tubular irradiation chamber. In one embodiment, a method is disclosed for joining the ends of a first optical cable and a second optical cable together. The method includes the steps of abutting the end of the first optical cable to the end of the second optical cable, applying reactive adhesive to the abutted ends, and directing radiation within the absorption spectrum of the reactive adhesive onto the adhesive until the adhesive is sufficiently cured.

Abstract: A process for producing a nitrogen-enriched vapor product from a supply of a nitrogen-rich liquid uses a purifying device and a distillation column having a distillation zone. The process includes the steps of: feeding at least a portion of the supply of the nitrogen-rich liquid to the distillation zone at a first location; feeding a stream of a gas containing nitrogen and at least one contaminant to the purifying device, wherein the gas is cooled by a cryogenic liquid whereby at least a portion of the at least one contaminant condenses, solidifies, or dissolves; eventually feeding at least a portion of the cool gas from the purifying device to the distillation zone at a second location below the first location; withdrawing a stream of the nitrogen-enriched vapor product from the distillation zone; and withdrawing a stream of an oxygen-enriched liquid from the distillation zone.

Abstract: The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments.

Abstract: The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments.

Abstract: The invention proposes a dispenser of paper, or other equivalent product, including a housing storing the product in the form of folded sheets to be dispensed through a dispensing opening. The paper is contained in a detachable cartridge compatible with the paper dimensions and assembled to the dispenser inside the housing. The cartridge includes an end wall situated opposite an opening of the housing wherein is located a dispensing slot of which the shape matches the paper sheets to be dispensed. The cartridge includes walls which guide the stack of folded sheets.