Abstract: A joint and method for producing a joint in an endovascular graft. In one embodiment, a flap of a flexible material portion of an endovascular graft is folded about a portion of an expandable member to form a loop portion. The flap is secured in the loop configuration so that tensile force on the expandable member is transferred into a shear force on the fixed portion of the flap.

Abstract: A joint and method for producing a joint in an endovascular graft. In one embodiment, a flap of a flexible material portion of an endovascular graft is folded about a portion of an expandable member to form a loop portion. The flap is secured in the loop configuration so that tensile force on the expandable member is transferred into a shear force on the fixed portion of the flap.

Abstract: An obstruction light is disclosed herein. The obstruction light can include a reflector having a first parabolic portion and a second parabolic portion. The obstruction light can also include a light assembly having at least one array of light sources disposed adjacent to the reflector between the first parabolic portion and the second parabolic portion.

Abstract: A joint and method for producing a joint in an endovascular graft. In one embodiment, a flap of a flexible material portion of an endovascular graft is folded about a portion of an expandable member to form a loop portion. The flap is secured in the loop configuration so that tensile force on the expandable member is transferred into a shear force on the fixed portion of the flap.

Abstract: Support clips and systems thereof are provided. Support clips include a web, a lower flange, and an upper flange. The lower flange extends from the web orthogonally. The upper flange extends from the web, towards the lower flange, at an angle. The lower flange includes an aperture for receiving a fastener. Systems include support clips of the present invention coupling a ballast housing to a mounting module. The lower flange is secured to the housing, and the upper flange engages the mounting module, such that the housing is supported by the support clip against the mounting module when in a latched position. A user is able to secure a fastener through the support clip aperture and openings in the housing and mounting module without having to use additional hands.

Abstract: The invention relates to compounds of Formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.

Abstract: A light emitting diode (LED) floodlight is described herein. The LED floodlight can include a LED housing assembly coupled to a driver assembly. The LED housing can include a number of LEDs mounted on a front side of a LED housing and a number of heat sink protrusions extending from a back side of the LED housing. The driver assembly can include a driver mounted within a driver housing, where the front side of the driver housing couples to the end of the heat sink protrusions that extend from the back side of the LED housing. The LEDs may be coupled to a number of reflectors. The reflectors can include a reflector body having a top portion and a bottom portion. The top portion can form a shape that is an elongated version of the shape formed by the bottom portion.

Abstract: An endovascular delivery system includes a bifurcated prosthesis including a main tubular body having an open end and opposed ipsilateral and contralateral legs and a delivery catheter for deployment of the prosthesis. The delivery catheter includes an elongate outer tubular sheath, an elongate inner tubular member releasably disposed within the elongate outer tubular sheath and an elongate crossover guidewire slidably disposed within the elongate outer tubular sheath and extending through the ipsilateral and contralateral legs.

Abstract: A device and method for the manufacture of medical devices, specifically, endovascular grafts, or sections thereof. Layers of fusible material are disposed upon a shape forming member and seams formed between the layers in a configuration that can produce inflatable channels in desired portions of the graft. After creation of the seams, the fusible material of the inflatable channels may be fixed while the channels are in an expanded state. A five axis robotic seam forming apparatus may be used to create the seams in the layers of fusible material.

Abstract: Stent-grafts for treating thoracic aortic aneurysms and abdominal aortic aneurysms include graft portions having inflatable channels and graft extensions. The graft extensions include an undulating wire stent and porous, but substantially fluid impermeable, polytetrafluoroethylene (PTFE) graft materials.

Abstract: Lighting assemblies or lighting fixtures suitable for use in a hazardous location are provided. Generally, the lighting fixtures include a light source assembly, a heat sink, a driver housing or gear module, a thermally conductive sealing member between the light source assembly and the heat sink, and a thermally nonconductive sealing member or a thermally semi-conductive sealing member positioned between the heat sink and the driver housing. The conductive sealing member has a thermal conductivity of at least about 6 Watts per meter-Kelvin, and/or a thermal impedance of less than about 0.21 degree-C inch squared per Watt. The lighting fixtures have controlled directional heat transfer from the light source assembly to the exterior of the lighting fixture, while minimizing the heat transferred to the driver housing.

Abstract: The invention relates to compounds of Formula (1) and to processes for the preparation of intermediates used in the preparation of compositions containing and the uses of such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.

Abstract: A joint and method for producing a joint in an endovascular graft. In one embodiment, a flap of a flexible material portion of an endovascular graft is folded about a portion of an expandable member to form a loop portion. The flap is secured in the loop configuration so that tensile force on the expandable member is transferred into a shear force on the fixed portion of the flap.

Abstract: Lighting assemblies or lighting fixtures suitable for use in a hazardous location are provided. Generally, the lighting fixtures include a light source assembly, a heat sink, a driver housing or gear module, and a conductive sealing member between the light source assembly and the heat sink. The conductive sealing member has a thermal conductivity of at least about 6 Watts per meter-Kelvin, and/or a thermal impedance of less than about 0.21 degree-C. inch squared per Watt. The lighting fixtures have controlled directional heat transfer from the light source assembly to the exterior of the lighting fixture, while minimizing the heat transferred to the driver housing.

Abstract: A light emitting diode (LED) floodlight is described herein. The LED floodlight can include a LED housing assembly coupled to a driver assembly. The LED housing can include a number of LEDs mounted on a front side of a LED housing and a number of heat sink protrusions extending from a back side of the LED housing. The driver assembly can include a driver mounted within a driver housing, where the front side of the driver housing couples to the end of the heat sink protrusions that extend from the back side of the LED housing. The LEDs may be coupled to a number of reflectors. The reflectors can include a reflector body having a top portion and a bottom portion. The top portion can form a shape that is an elongated version of the shape formed by the bottom portion.

Abstract: An indexed book of information bits has a hierarchal structure of primary headings and secondary headings within each primary heading. Each secondary heading includes a group of information bits associated therewith. The pages of the book are bound at first edges in a spine, include primary markings representing primary headings along second edges, and include secondary markings representing secondary headings along third edges. Indicating portions are provided along each of the second and third edges to associate each page with a respective primary heading and a respective secondary heading.

Abstract: Devices that are enabled to communicate with each other via an ad hoc conference mode and an infrastructure supported conference mode, are provided with processing capabilities that can allow them to evaluate one or more resources required to support an ad hoc conference communication session and/or one or more quality metrics associated with the ad hoc conference communication session, and determine whether one or more resources or metrics are outside optimal operating parameters. If so, the processing logic can initiate a transition from the ad hoc conference communication session to an infrastructure supported conference communication session hosted at a conference server.

Abstract: Embodiments are directed in part to endovascular prostheses and methods of deploying same. Embodiments may be directed more specifically to stent grafts and methods of positioning and deploying such devices within the body of a patient.