Patents by Inventor Patrick Walker

Patrick Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6951868
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is any of: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: October 4, 2005
    Assignee: Pfizer Inc.
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi, Jr.
  • Patent number: 6919359
    Abstract: The invention provides compounds of Formula I: Azabicyclo-N(R1)—C(?X)—W??Formula I These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: July 19, 2005
    Assignee: Pfizer Inc
    Inventors: David W. Piotrowski, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, Alice L. Bodnar, Vincent E. Groppi, Jr., Daniel Patrick Walker, Brad A. Acker
  • Patent number: 6911543
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: June 28, 2005
    Assignee: Pfizer Inc.
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Steven Charles Reitz
  • Patent number: 6894042
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: May 17, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker
  • Patent number: 6869946
    Abstract: The invention provides compounds of Formula I: wherein m1 is 0 or 1; m2 is 1 or 2; R1 is —H, alkyl, halogenated alkyl, substituted alkyl, cycloalkyl, or phenyl; R2 is —H, alkyl, halogenated alkyl, substituted alkyl, cycloalkyl, or phenyl, provided that when m1 is 1 at least one of R1 and R2 is —H; or a pharmaceutically acceptable salt, pharmaceutical composition, a pure enantiomer or racemic mixture thereof. The invention also provides a method for treating a disease or condition in a mammal, wherein the ?7 nicotinic acetylcholine receptor is implicated and for treating diseases where there is a sensory-gating deficit in a mammal comprising administering to a mammal a therapeutically effective amount of a compound of Formula I. These compounds may be in the form of pharmaceutical salts or compositions, and may be in pure enantiomeric form or may be racemic mixtures.
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: March 22, 2005
    Assignee: Pfizer Inc
    Inventors: Eric Jon Jacobsen, Daniel Patrick Walker, Jason K. Myers, David W. Piotrowski, Vincent E. Groppi, Jr.
  • Publication number: 20050047806
    Abstract: In a hybrid jumping (HJD) or hybrid scavengeless (HSD) development station used in xerography, a control system avoids arcing conditions in a gap between a donor member and an image receptor. In a set-up operation, a series of test patches are produced while incrementing the AC amplitude in the gap. A change in reflectivity of the patches as a function of the AC amplitude in the gap is measured and the actual width of the gap is thus estimated. An accurate estimate of the gap width can then be used in a control algorithm.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 3, 2005
    Inventors: Song-Feng Mo, Wendy Apton, Stephen Randall, Patrick Walker
  • Patent number: 6858613
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat conditions or diseases in which ?7 is known to be involved.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: February 22, 2005
    Assignee: Pfizer Inc.
    Inventors: Bruce N. Rogers, David W. Piotrowski, Daniel Patrick Walker, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Vincent E. Groppi, Jr.
  • Patent number: 6852716
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals to treat diseases or conditions in which ?7 is known to be involved.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: February 8, 2005
    Assignee: Pfizer Inc
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi, Jr.
  • Patent number: 6849620
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is W0 is a bicyclic moiety and is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: October 17, 2002
    Date of Patent: February 1, 2005
    Assignee: Pfizer Inc
    Inventors: Daniel Patrick Walker, Eric Jon Jacobsen, David W. Piotrowski, Brad A. Acker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, Vincent E. Groppi, Jr.
  • Publication number: 20040254373
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 30, 2004
    Publication date: December 16, 2004
    Applicant: Pfizer Inc
    Inventors: David W. Piotrowski, Bruce N. Rogers, William W. McWhorter, Daniel Patrick Walker, Jeffrey W. Corbett, Vincent E. Groppi, Daniel G. Rudmann
  • Publication number: 20040249150
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 29, 2004
    Publication date: December 9, 2004
    Applicant: Pfizer Inc
    Inventors: David W. Piotrowski, Bruce N. Rogers, William W. McWhorter, Daniel Patrick Walker, Jeffrey W. Corbett, Vincent E. Groppi, Daniel G. Rudmann
  • Patent number: 6828330
    Abstract: The invention provides compounds of Formula I: wherein W0 is a bicyclic moiety and is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful to treat diseases or conditions in which &agr;7 is known to be involved.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: December 7, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventors: Daniel Patrick Walker, Donn G. Wishka, David W. Piotrowski, Vincent E. Groppi, Jr.
  • Publication number: 20040224976
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 15, 2004
    Publication date: November 11, 2004
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Publication number: 20040224977
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 10, 2004
    Publication date: November 11, 2004
    Inventors: Daniel Patrick Walker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, David W. Piotrowski, Vincent E. Groppi
  • Publication number: 20040157878
    Abstract: Radiolabeled ligands useful as probes for determining the relative abundance, receptor occupancy, and/or function of nicotinic acetylcholine receptors. The compounds of Formula I as described herein are labeled with a radioactive isotopic moiety such as 11C, 18F, 76Br, 123I or 125I. Disorders are diagnosed by administering to a mammal a detectably labeled compound and detecting the binding of that compound to the nAChR. The compounds that have been administered are detected using methods including, but not limited to, position emission topography and single-photon emission computed tomography. The present invention is useful in diagnosing a wide variety of diseases and disorders as discussed herein.
    Type: Application
    Filed: December 5, 2003
    Publication date: August 12, 2004
    Inventors: Bruce Nelson Rogers, David W. Piotrowski, Vincent Edward Groppi, Eric Jon Jacobsen, Jason Kenneth Myers, Daniel Patrick Walker, Donn Gregory Wishka, Marc Bradley Skaddan
  • Publication number: 20040147522
    Abstract: The invention discloses compounds that are selective &agr;7 nAChR agonists and 5-HT3 antagonists. The compounds are useful for treating many CNS diseases.
    Type: Application
    Filed: October 31, 2003
    Publication date: July 29, 2004
    Inventors: Erik Ho Fong Wong, Luz A. Cortes-Burgos, Bruce Nelson Rogers, David W. Piotrowski, Daniel Patrick Walker, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka
  • Publication number: 20040087616
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: July 25, 2003
    Publication date: May 6, 2004
    Inventors: David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Daniel Patrick Walker, Donn G. Wishka, Vincent E. Groppi
  • Publication number: 20030236287
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: April 25, 2003
    Publication date: December 25, 2003
    Inventors: David W. Piotrowski, Bruce N. Rogers, William W. McWhorter, Daniel Patrick Walker, Jeffrey W. Corbett, Vincent E. Groppi, Daniel G. Rudmann
  • Publication number: 20030236279
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 10, 2003
    Publication date: December 25, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi
  • Publication number: 20030236270
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Eric Jon Jacobsen, Jason K. Myers, Daniel Patrick Walker, Donn G. Wishka, Steven Charles Reitz, David W. Piotrowski, Brad A. Acker, Vincent E. Groppi