Patents by Inventor Patrizio Mattei

Patrizio Mattei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazole derivatives
    Patent number: 6686381
    Abstract: Compounds of formula I are provided as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5, n, m and A have the significance disclosed in the specification, and can be used for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: February 3, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrizio Mattei, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Sven Taylor
  • THIAZOLE DERIVATIVES
    Publication number: 20030225141
    Abstract: Compounds of formula I are provided 1
    Type: Application
    Filed: February 26, 2003
    Publication date: December 4, 2003
    Inventors: Patrizio Mattei, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Sven Taylor
  • Pyrimidine derivatives
    Patent number: 6657060
    Abstract: Pyrimidine derivatives have been found to be useful as neuropeptide Y receptor ligands and particularly as antagonists. These pyrimidine derivatives may be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, diabetes, eating disorders, and obesity.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 2, 2003
    Assignee: Hoffman-La Roche Inc.
    Inventors: Volker Breu, Frank Dautzenberg, Patrizio Mattei, Werner Neidhart, Philippe Pflieger
  • Fused indole derivatives
    Patent number: 6610685
    Abstract: The present invention is a chemical compound of formula (I) or a pharmaceutically acceptable salt, solvate and ester thereof, wherein R1 to R4 and n are as defined in the specification. A compound of formula 1 is useful as a pharmaceutical composition for the treatment or prevention of disorders of the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes, obesity and sleep apnoea.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: August 26, 2003
    Assignees: Hoffmann-La Roche Inc., Vernalis Research Limited
    Inventors: Jonathan Mark Bentley, Michael John Bickerdike, Paul Hebeisen, Guy Anthony Kennett, Sean Lightowler, Patrizio Mattei, Jacques Mizrahi, Timothy James Morley, Jean-Marc Plancher, Hans Richter, Stephan Roever, Sven Taylor, Steven Paul Vickers
  • Quinoline derivatives
    Publication number: 20030158179
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: September 19, 2002
    Publication date: August 21, 2003
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Quinoline derivatives
    Publication number: 20030153553
    Abstract: Compounds of general formula I 1
    Type: Application
    Filed: February 4, 2003
    Publication date: August 14, 2003
    Inventors: Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Pyrido [2,1-a] isoquinoline derivatives
    Publication number: 20030149071
    Abstract: The present invention provides compounds of formula (I) 1
    Type: Application
    Filed: December 17, 2002
    Publication date: August 7, 2003
    Inventors: Luca Claudio Gobbi, Thomas Luebbers, Patrizio Mattei, Robert Narquizian, Pierre Charles Wyss
  • Pyrimidinyl methyl indole derivatives with antibacterial activity
    Publication number: 20030119857
    Abstract: This invention relates to indole derivatives of the general formula (I) wherein R1 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfonyl, dialkylsulfamoyl, N-cycloalkyl-N-alkylsulfamoyl, heterocyclylalkyl or phenylalkyl; R2 is hydrogen, halogen, alkyl, alkanoyl, phenyl, phenylalkyl or heterocyclylalkyl; R3 is hydrogen, alkyl; and R4 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfonyl, dialkylsulfamoyl, N-cycloalkyl-N-alkylsulfamoyl, heterocyclylalkyl, or phenylalkyl; and pharmaceutically acceptable acid addition salts of these compounds, there use as therapeutically active substances; medicaments based on these substances, optionally in combination with sulphonamides, and their production; the use of these substances as medicaments and for the production of antibacterially-active medicaments; as well as the manufacture of the compounds of formula (I) and their pharmaceutically acceptab
    Type: Application
    Filed: October 25, 2002
    Publication date: June 26, 2003
    Inventors: Patrizio Mattei, Philippe Pflieger
  • Piperazine derivatives
    Publication number: 20020169163
    Abstract: Piperazine derivatives, as well as pharmaceutically acceptable salts, solvates and esters thereof, can be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, damage to the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes insipidus, type II diabetes, obesity and sleep apnoea.
    Type: Application
    Filed: March 7, 2002
    Publication date: November 14, 2002
    Inventors: Paul Hebeisen, Patrizio Mattei, Marc Muller, Hans Richter, Stephan Roever, Sven Taylor
  • Novel indole derivatives
    Publication number: 20020160997
    Abstract: The present invention is a chemical compound of formula (I) 1
    Type: Application
    Filed: December 14, 2001
    Publication date: October 31, 2002
    Inventors: Jonathan Mark Bentley, Michael John Bickerdike, Paul Hebeisen, Guy Anthony Kennett, Sean Lightowler, Patrizio Mattei, Jacques Mizrahi, Timothy James Morley, Jean-Marc Plancher, Hans Richter, Stephan Roever, Sven Taylor, Steven Paul Vickers
  • Novel piperazine derivatives
    Publication number: 20020143020
    Abstract: The present invention is a chemical compound of formula (I) 1
    Type: Application
    Filed: December 7, 2001
    Publication date: October 3, 2002
    Inventors: David Reginald Adams, Jonathan Mark Bentley, James Edward Paul Davidson, Claire Elizabeth Dawson, Ashley Roger George, Howard Langham Mansell, Patrizio Mattei, Jacques Mizrahi, Matthias Heinrich Nettekoven, Robert Mark Pratt, Stephan Roever, Jonathan Richard Anthony Roffey, Jean-Luc Specklin, Henri Stalder, Kerry Wilkinson
  • Pyrimidine derivatives
    Publication number: 20020086858
    Abstract: Pyrimidine derivatives have been found to be useful as neuropeptide Y receptor ligands and particularly as antagonists. These pyrimidine derivatives may be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, diabetes, eating disorders, and obesity.
    Type: Application
    Filed: November 8, 2001
    Publication date: July 4, 2002
    Inventors: Volker Breu, Frank Dautzenberg, Patrizio Mattei, Werner Neidhart, Philippe Pflieger