Abstract: A modular well pad system, which includes an inlet module, a 2 well-pair module and a 3 well-pair module. The inlet module, one or more 2 well-pair modules and one or more 3 well-pair modules may be configured to build an interconnected well pad system for accommodating two to twelve well-pairs wherein standardized connections enable the 2 well-pair module and the 3 well-pair module to be coupled together, to the inlet module, another 2 well-pair module and/or another 3 well-pair module.

Abstract: A modular well pad system, which includes a first inlet module, a second inlet module, a 1 well-pair module and a 2 well-pair module. The first and second inlet modules, one or more 1 well-pair modules and one or more 2 well-pair modules may be configured to build an interconnected well pad system for accommodating one to twelve well-pairs wherein standardized connections enable the 1 well-pair module and the 2 well-pair module to be coupled together, to the second inlet module, another 1 well-pair module and/or another 2 well-pair module.

Abstract: A reagent dosing system for dosing a reagent into the exhaust gas stream of an internal combustion engine includes a reagent tank for storing a supply of reagent; an injector module including an atomizing dispenser and a positive-displacement metering pump which draws reagent from the reagent tank and delivers it to the dispenser; a supply line coupling the reagent tank to the injector module; a dosing control unit operable to control the injector module to inject reagent into the exhaust gas stream; and an additional priming pump arranged, in use, to urge reagent along the supply line toward the injector module under selected conditions.

Abstract: A pumping assembly is provided which is suitable for use in a variety of dosing pumps. The pumping assembly comprises a pump body with a pump bore, and a sleeve fixed within the pump bore. The sleeve has a first end, a second end and a sleeve bore. A plunger is adapted to enter the first end of the sleeve and to reciprocate within the sleeve bore. The sleeve has at least one port to allow fluid flow through a wall of the sleeve. The, or each, port is elongated in a direction substantially orthogonal to a direction of reciprocation.

Abstract: A pump assembly having improved cooling for use in a selective catalytic reduction system is disclosed. The pump assembly comprises a pump housing having a body portion and a nozzle portion extending from the body portion, a jacket including a cavity for receiving the pump housing, first and second ports for cooling fluid, and a flow guide disposed between the jacket and the pump housing. The cavity includes a first compartment for cooling fluid defined in part by the flow guide and in part by the pump housing and being in fluid communication with the first port; and a second compartment for cooling fluid defined in part by the flow guide and in part by the jacket. The first compartment is in fluid communication with the second port by way of the second compartment.

Abstract: A reagent dosing system for dosing a reagent into the exhaust gas stream of an internal combustion engine includes a reagent tank for storing a supply of reagent; an injector module including an atomising dispenser and a positive-displacement metering pump which draws reagent from the reagent tank and delivers it to the dispenser; a supply line coupling the reagent tank to the injector module; a dosing control unit operable to control the injector module to inject reagent into the exhaust gas stream; and an additional priming pump arranged, in use, to urge reagent along the supply line toward the injector module under selected conditions.

Abstract: A reagent dosing system for dosing a reagent into the exhaust gas stream of an internal combustion engine includes a reagent tank for storing a supply of reagent; an injector module including an atomizing dispenser and a positive-displacement metering pump which draws reagent from the reagent tank and delivers it to the dispenser; a supply line coupling the reagent tank to the injector module; a dosing control unit operable to control the injector module to inject reagent into the exhaust gas stream; and an additional priming pump arranged, in use, to urge reagent along the supply line toward the injector module under selected conditions.

Abstract: The invention relates to compounds of formula (I) wherein X1, X2, R1 to R4, m, and n have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds, the preparation of such compounds as well as the use as medicaments.

Abstract: The invention relates to compounds of formula (I) wherein m, o, Ra, Rb, R1 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds, the preparation of the compounds as well as their use as medicaments.

Abstract: The invention relates to compounds of formula (I) wherein m, n, R1, T0 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds as well as methods of treating mTOR related diseases.

Abstract: A control system comprises a TRAS actuator 14, a VAFN actuator 40, and a control arrangement 52 operable to control the operation of the TRAS actuator 14 and the VAFN actuator 40, wherein at least one control circuit 54 of the control arrangement 52 is a common control circuit, common to the operation of both the TRAS actuator 14 and the VAFN actuator 40.

Abstract: A mounting arrangement for attaching a pump arrangement to an exhaust pipe at a boss includes a delivery nozzle section and a remaining section including a pump body. The mounting arrangement includes a packing for supporting the pump body at the remaining section of the pump arrangement.

Abstract: The invention relates to compounds of formula (I) wherein m, n, R1, T0 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds as well as methods of treating mTOR related diseases.

Abstract: A method of dosing a reagent into an exhaust gas stream of an internal combustion engine having an SCR catalyst, the method comprising injecting reagent from a reagent tank into the exhaust gas stream at a position upstream of the SCR catalyst using a reagent injector in accordance with a first dosing schedule in order to remediate a predetermined proportion of NOx in the exhaust gas stream, the first dosing schedule being associated with a first range of engine operating conditions; and injecting reagent from the reagent tank into the exhaust gas stream at a position upstream of the SCR catalyst using a reagent injector in accordance with a second dosing schedule in order to enable heat transfer between the reagent injector and said injected reagent, the second dosing schedule being associated with a second range of engine operating conditions.

Abstract: A reagent dosing system for dosing a reagent into the exhaust gas stream of an internal combustion engine includes a reagent tank for storing a supply of reagent; an injector module including an atomising dispenser and a positive-displacement metering pump which draws reagent from the reagent tank and delivers it to the dispenser; a supply line coupling the reagent tank to the injector module; a dosing control unit operable to control the injector module to inject reagent into the exhaust gas stream; and an additional priming pump arranged, in use, to urge reagent along the supply line toward the injector module under selected conditions.

Abstract: The invention relates to compounds of formula (I) wherein m, o, Ra, Rb, R1 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds, the preparation of the compounds as well as their use as medicaments.

Abstract: The invention relates to compounds of formula (I) wherein X, R1, R2, T0, o have the meaning as cited in the description and the claims. The compounds of formula I are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds of formula I, the preparation of such compounds as well as the use as medicaments.

Abstract: A pump assembly having improved cooling for use in a selective catalytic reduction system is disclosed. The pump assembly comprises a pump housing having a body portion and a nozzle portion extending from the body portion, a jacket including a cavity for receiving the pump housing, first and second ports for cooling fluid, and a flow guide disposed between the jacket and the pump housing. The cavity includes a first compartment for cooling fluid defined in part by the flow guide and in part by the pump housing and being in fluid communication with the first port; and a second compartment for cooling fluid defined in part by the flow guide and in part by the jacket. The first compartment is in fluid communication with the second port by way of the second compartment.

Abstract: The invention relates to compounds of formula (I) wherein X1, X2, R1 to R4, m, n have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.

Abstract: A mounting arrangement for attaching a pump arrangement to an exhaust pipe at a boss includes a delivery nozzle section and a remaining section including a pump body. The mounting arrangement includes a packing for supporting the pump body at the remaining section of the pump arrangement.