Patents by Inventor Paul A. Moore
Paul A. Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130078253Abstract: Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.Type: ApplicationFiled: March 30, 2012Publication date: March 28, 2013Applicant: CELERA CORPORATIONInventors: Dong FANG, Paul MOORE, Steve RUBEN, Sudeepta AGGARWAL
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Patent number: 8372948Abstract: The present invention relates to 12 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: GrantFiled: November 3, 2008Date of Patent: February 12, 2013Assignee: Human Genome Sciences, Inc.Inventors: Jian Ni, Paul E. Young, Joseph J. Kenny, Henrik S. Olsen, Paul A. Moore, Ying-Fei Wei, John M. Greene, Steven M. Ruben, Ding Liu, Paul R. Crocker
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Patent number: 8364948Abstract: Cluster aliasing is implemented for a cluster of a plurality of computer-based members. The aliased cluster supports secured communication with a non-member node. The cluster aliasing provides an appearance to the non-member node of a common network address for the plurality of members. In supporting the secured communication, a first of the plurality of members is assigned to process secure inbound data directed to the common network address from the non-member node, and a second, different of the plurality of members is assigned to send secure outbound data from the common network address to the non-member node.Type: GrantFiled: December 15, 2004Date of Patent: January 29, 2013Assignee: Hewlett-Packard Development Company, L.P.Inventors: Gary L. Grebus, Dan C. Vuong, Paul Moore
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Publication number: 20130006743Abstract: A computer-implemented method for in-application advertising display on a second computer using a first computer. A request is received on a first computer to display an advertisement on a second computer, the request from the second computer and including an identification of an application and a location information. The first computer selects an advertisement containing a deal comprised of a discount for prepurchase from a first company and a reward from a second company. The second company is selected based on the identification of the application and the selection is based on both the identification of the application and the location information. The first computer transmits the advertisement to the second computer. The first computer receives a signal from the second computer indicating a purchase of the deal by a user of the second computer.Type: ApplicationFiled: June 20, 2012Publication date: January 3, 2013Applicant: CROWDMOB, INC.Inventors: Matthew Paul Moore, Damon Willis Grow, Alex Xu Han
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Patent number: 8321523Abstract: A method of maintaining Network Information Service (NIS) maps where modifying information about any of the network entities described by the NIS maps requires only incremental update of the NIS maps instead of full NIS map regeneration. A further method of detecting when network entity records on a network directory server change so that NIS map updates are necessary.Type: GrantFiled: April 24, 2006Date of Patent: November 27, 2012Assignee: Centrify CorporationInventors: Craig L. Lawson, Paul Moore
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Publication number: 20120294796Abstract: The present invention relates to antibodies that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.Type: ApplicationFiled: May 4, 2012Publication date: November 22, 2012Applicant: MACROGENICS, INC.Inventors: Leslie S. Johnson, Ling Huang, Paul A. Moore, Deryk T. Loo, Francine Z. Chen
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Publication number: 20120273446Abstract: The present invention is directed towards a dental bur storage device having a plurality of dental bur receiving holes capable of retaining a plurality of different dental bur types having different shank diameters, wherein, each of the plurality of dental bur receiving holes is tapered to allow a retaining fit to be established with any one of the plurality of different dental bur types having different shank diameters. The advantage of using a receiving hole that has a tapered form is that different types of dental burs having different diameters of shanks may be retained by the receiving holes in the dental bur storage device. This allows a wide range of different brands and different types of dental burs to be accommodated on one single dental bur storage device which greatly simplifies the process of selecting a dental bur for a dentist, particularly during a dental treatment.Type: ApplicationFiled: October 29, 2010Publication date: November 1, 2012Inventor: Paul Moore
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Publication number: 20120251148Abstract: Systems and a method for image forming systems to skip over the non-printing photoreceptor area in order to not skip a label position on a continuous print web medium. A vacuum assembly is coupled to a controller that controls different vacuum pressures at each vacuum roller therein. The vacuum rollers provide drag and drive forces to skip a seam of the photoreceptor and a residual length based on the number and size of images on the photoreceptor.Type: ApplicationFiled: March 28, 2011Publication date: October 4, 2012Applicant: XEROX CORPORATIONInventors: Kenneth Paul Moore, Frank Albert Porter, Bruce Allen Thompson, Todd Maurice Uthman, Ron Edward Dufort, Venkata Bharadwaj Chivukula, Roger Gaylord Leighton
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Publication number: 20120253946Abstract: There are disclosed computerized systems and methods that provide recommended bid amounts to advertisers, information providers and the like, for example, for categories in which the advertisers and information providers have existing or current bids, based on time fractals. The time fractals are movable within a window to continuously provide the aforementioned recommended bid amounts, for the category.Type: ApplicationFiled: March 28, 2012Publication date: October 4, 2012Applicant: ADKNOWLEDGE, INC.Inventors: DEREK PAUL MOORE, DANIEL ARON WAJCMAN, ALBERTO JORGE SIMON
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Patent number: 8266301Abstract: A mechanism for the deployment of asynchronous agentless agent functionality in clustered environments. An agentless agent execution node in an agentless agent execution node cluster receives a context message comprising an asynchronous operation request and an execution context from a messaging service. The agent node determines if an entry for the execution context exists in an execution context state table of the agent node. If no entry exists, the agent node creates an execution context entry in the execution context state table of the agent node. The agent node retrieves an asynchronous code module associated with the asynchronous operation from a central repository. The asynchronous code module is then executed on a managed resource to detect asynchronous code events occurring on the managed resource. When asynchronous code events are detected at the managed resource, the agent node sends a message comprising the asynchronous code events to a management server.Type: GrantFiled: March 4, 2009Date of Patent: September 11, 2012Assignee: International Business Machines CorporationInventors: David Paul Moore, Zoran Radenkovic, John T. Robertson
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Patent number: 8257187Abstract: A constant velocity (CV) joint assembly comprising a CV joint and an input member is disclosed. The CV joint that has a cage and a gear between which rotational drive can be transmitted. The input member is connected to the cage of the CV joint for transmission of rotational drive about an axis from an external component to the CV joint. The rotational drive is transmitted between the cage and the input member through interacting drive faces that are disposed in a plane that is generally parallel to the axis. The cage and the input member are retained in interconnection by fastening means that are not responsible for transmission of rotational drive between the cage and the input member. By separating the task of transmission of torque and retention of the connection between the cage and the input member, the fastening means required to perform the latter task can be comparatively light.Type: GrantFiled: February 13, 2008Date of Patent: September 4, 2012Assignee: Xtrac LimitedInventors: Michael Kerr, Adrian Paul Moore
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Publication number: 20120177659Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.Type: ApplicationFiled: December 29, 2011Publication date: July 12, 2012Applicant: CELERA CORPORATIONInventors: Steve RUBEN, Karen VAN ORDEN, Candy N. LEE, Tao HE, Mehdi MESRI, Elizabeth G. JOSELOFF, Paul MOORE, Katherine MCKINNON, Bruno DOMON
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Patent number: 8200825Abstract: The present invention comprises a system for the control of multiple remote resources. A plurality of user stations, each comprising a keyboard, video screen and a mouse, communicate with a server management unit. The server management unit is comprised of a server chassis, matrix switch and a switch server. Remote resources are each connected to a port of a multiplexer or to a server interface. A user station connects to a remote resource by making a request to the server management unit. The switch server identifies the multiplexer or server interface port to which the resource is connected from a database. A request is made to a remote interface server connected to the multiplexer and server interfaces and the remote interface server connects the appropriate ports of the server management unit and the multiplexer or server interface.Type: GrantFiled: February 27, 2002Date of Patent: June 12, 2012Assignee: Raritan Computer Inc.Inventors: Phil Bates, Jeremy Young, Paul Moore, Sean Dynan
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Publication number: 20120131700Abstract: The invention provides seed treatment compositions as well as their use, methods for treating seeds, methods of protecting plants against pests and also treated seeds and plants. In one embodiment there is provided a method of treating a seed with a seed treatment composition to induce a plant resistance mechanism against one or more pests in a plant grown from said seed.Type: ApplicationFiled: January 12, 2012Publication date: May 24, 2012Applicant: Plant Bioscience LimitedInventors: Michael Richard Roberts, Nigel Duncan Paul, Jane Elizabeth Taylor, Patricia Croft, Jason Paul Moore
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Publication number: 20120122762Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: January 26, 2012Publication date: May 17, 2012Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, D. Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, Zhizhen Zeng, Hla Kyaw
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Publication number: 20120119571Abstract: A reconfigurable vehicle power and signal distribution system (10) is disclosed. The system comprises at least one conduit section (11) for housing a first and second power rail (22), and a communication line (20) for communicating signals along the conduit. The system further comprises a transfer hub (27) which enables the transfer of power and signals to a distribution hub that comprises a plurality of terminals for separately providing conditioned power to various system modules of the vehicle. The distribution of power from the distribution hub is dependent on signals received from a control unit via the communication line, which controls the power usage within the vehicle. The system enables the at least one conduit section, transfer hub and distribution hub to be reconfigured according to the topography of the vehicle.Type: ApplicationFiled: June 22, 2010Publication date: May 17, 2012Applicant: GENERAL DYNAMICS UNITED KINGOOM LIMITEDInventors: Paul Moore, James Humphries
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Patent number: 8168586Abstract: Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.Type: GrantFiled: November 21, 2008Date of Patent: May 1, 2012Assignee: Celera CorporationInventors: Dong Fang, Paul Moore, Steve Ruben, Sudeepta Aggarwal
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Patent number: 8143026Abstract: The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.Type: GrantFiled: August 3, 2009Date of Patent: March 27, 2012Assignee: Human Genome Sciences, Inc.Inventors: Craig A. Rosen, William A. Haseltine, Steven M. Ruben, Paul A. Moore, Jason B. Bock, David LaFleur
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Patent number: 8115053Abstract: The invention provides seed treatment compositions as well as their use, methods for treating seeds, methods of protecting plants against pests and also treated seeds and plants. In one embodiment there is provided a method of treating a seed with a seed treatment composition to induce a plant resistance mechanism against one or more pests in a plant grown from said seed.Type: GrantFiled: July 12, 2007Date of Patent: February 14, 2012Assignee: Plant Bioscience LimitedInventors: Michael Richard Roberts, Nigel Duncan Paul, Jane Elizabeth Taylor, Patricia Croft, Jason Paul Moore
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Publication number: 20110314056Abstract: A method of assigning the UNIX computers in a network to one of a plurality of groups called zones, of creating independent sets of UNIX identity information for each network entity (user or group) for separate zones, and of associating an entity's sets of UNIX entity information with a single global entity record for the entity in the network's identity resolver. A further method of allowing a UNIX computer to request entity information from the identity resolver, and of the identity resolver returning resolved entity information appropriate for the requesting computer's zone. A further method of managing sets of zone-specific UNIX identity information in the identity resolver to ensure that entity names and entity identification numbers are not duplicated within a zone and to all the same names and numbers to be duplicated across zones. Other embodiments are also described.Type: ApplicationFiled: August 25, 2011Publication date: December 22, 2011Inventor: Paul Moore