Patents by Inventor Paul A. Moore

Paul A. Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES
    Publication number: 20150361181
    Abstract: Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.
    Type: Application
    Filed: April 24, 2015
    Publication date: December 17, 2015
    Inventors: Steve RUBEN, Tao HE, Candy LEE, Karen VAN ORDEN, Paul MOORE
  • System and Method for Gathering Information about a Subject in Close Proximity to a User
    Publication number: 20150341751
    Abstract: Techniques where a computer system is able to obtain information about a subject by communicating with a device that employs a limited range communication technology and is associated with the subject are described.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Inventors: Bradley Alan Eaton, David Pyron Biggers, JR., Dustin Paul Moore
  • Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof
    Patent number: 9150656
    Abstract: The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: October 6, 2015
    Assignee: MacroGenics, Inc.
    Inventors: Leslie S. Johnson, Paul A. Moore, Ling Huang, Deryk T. Loo, Francine Zhifen Chen
  • Antibodies Reactive with B7-H3, Immunologically Active Fragments Thereof and Uses Thereof
    Publication number: 20150274838
    Abstract: The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
    Type: Application
    Filed: June 1, 2015
    Publication date: October 1, 2015
    Applicant: MACROGENICS, INC.
    Inventors: Leslie S. Johnson, Paul A. Moore, Ling Huang, Deryk T. Loo, Francine Z. Chen
  • Antibodies Reactive with B7-H3, Immunologically Active Fragments Thereof and Uses Thereof
    Publication number: 20150259434
    Abstract: The present invention relates to antibodies and their fragments that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies and their immunoreactive fragments that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
    Type: Application
    Filed: June 1, 2015
    Publication date: September 17, 2015
    Applicant: MACROGENICS, INC.
    Inventors: Leslie S. Johnson, Paul A. Moore, Ling Huang, Deryk T. Loo, Francine Z. Chen
  • System and method for gathering information about a subject in close proximity to a user
    Patent number: 9137640
    Abstract: Techniques where a computer system is able to obtain information about a subject by communicating with a device that employs a limited range communication technology and is associated with the subject are described.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: September 15, 2015
    Assignee: a la mode technologies, inc.
    Inventors: Bradley Alan Eaton, David Pyron Biggers, Jr., Dustin Paul Moore
  • LATCH ASSEMBLY
    Publication number: 20150211266
    Abstract: A latch assembly includes a chassis, a latch bolt moveably mounted on the chassis and having a closed position for retaining a striker and an open position for releasing the striker, a pawl having an engaged position at which the pawl is engaged with the latch bolt to hold the latch bolt in the closed position and a disengaged position at which the pawl is disengaged from the latch bolt, thereby allowing the latch bolt to move to the open position, an eccentric arrangement defining an eccentric axis and a pawl axis remote from the eccentric axis. The eccentric arrangement is rotatable about the eccentric axis, and the pawl is rotatable about the pawl axis. When the pawl moves from the engaged position to the disengaged position, the eccentric arrangement rotates in one of a clockwise and a counter-clockwise direction about the eccentric axis.
    Type: Application
    Filed: November 3, 2014
    Publication date: July 30, 2015
    Inventors: Nigel V. Spurr, Gurbinder Singh Kalsi, Chris Rhodes, Robert Frank Tolley, David Peatey, Robert James Clawley, Paul Moore, Jean-Vincent Olivier, Sylvain Remi Chonavel, Denis Cavallucci
  • Method and Apparatus for Controlling an Exhaust Gas After-Treatment System
    Publication number: 20150204226
    Abstract: A combustion engine exhaust gas after-treatment device includes a first selective catalytic reduction (SCR) device, a second SCR device downstream of the first and a diesel particulate filter (DPF) between the first and second SCR devices. A method of dosing the after-treatment device includes: allowing dosing of the first SCR device with reductant only when its temperature is within its the operating temperature range; and allowing dosing of the second SCR device with reductant only when its temperature is within its different operating temperature range; and reducing the level of dosing of the first SCR device when requiring DPF regeneration.
    Type: Application
    Filed: July 26, 2013
    Publication date: July 23, 2015
    Applicant: Perkins Engines Company Limited
    Inventor: Paul Moore
  • Engine Boosting System and Method Therefor
    Publication number: 20150136093
    Abstract: The engine boosting system includes an engine having an intake manifold, exhaust manifold and exhaust gas recirculation loop fluidly connected therebetween. A boost circuit including a storage vessel is in fluid communication with the intake manifold and with the exhaust manifold. A throttle is located downstream of the exhaust manifold, the exhaust gas recirculation loop, and the boost circuit. A connection between the boost circuit and the intake manifold is independent of a connection between the exhaust gas recirculation loop and the intake manifold.
    Type: Application
    Filed: May 24, 2013
    Publication date: May 21, 2015
    Applicant: Perkins Engines Company Limited
    Inventor: Paul Moore
  • System and Method for Gathering Information about a Subject in Close Proximity to a User
    Publication number: 20150126219
    Abstract: Techniques where a computer system is able to obtain information about a subject by communicating with a device that employs a limited range communication technology and is associated with the subject are described.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 7, 2015
    Inventors: Bradley Alan Eaton, David Pyron Biggers, JR., Dustin Paul Moore
  • Maintaining multiple sets of identity data
    Patent number: 9015103
    Abstract: A method of assigning the UNIX computers in a network to one of a plurality of groups called zones, of creating independent sets of UNIX identity information for each network entity (user or group) for separate zones, and of associating an entity's sets of UNIX entity information with a single global entity record for the entity in the network's identity resolver. A further method of allowing a UNIX computer to request entity information from the identity resolver, and of the identity resolver returning resolved entity information appropriate for the requesting computer's zone. A further method of managing sets of zone-specific UNIX identity information in the identity resolver to ensure that entity names and entity identification numbers are not duplicated within a zone and to all the same names and numbers to be duplicated across zones. Other embodiments are also described.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: April 21, 2015
    Assignee: Centrify Corporation
    Inventor: Paul Moore
  • METHOD OF MEASUREMENT ON A MACHINE TOOL AND CORRESPONDING MACHINE TOOL APPARATUS
    Publication number: 20150066196
    Abstract: A method of scanning an object using an analogue probe mounted on a machine tool, so as to collect scanned measurement data along a nominal measurement line on the surface of the object, the analogue probe having a preferred measurement range. The method includes controlling the analogue probe and/or object to perform a scanning operation in accordance with a course of relative motion, the course of relative motion being configured such that, based on assumed properties of the surface of the object, the analogue probe will be caused to obtain data within its preferred measuring range, as well as cause the analogue probe to go outside its preferred measuring range, along the nominal measurement line on the surface of the object.
    Type: Application
    Filed: April 16, 2013
    Publication date: March 5, 2015
    Applicant: RENISHAW PLC
    Inventors: Michael Wooldridge, Paul Moore, John Ould
  • Systems and Methods for Restricting Application Binary Interfaces
    Publication number: 20150040216
    Abstract: Systems and methods for restricting application binary interfaces. An example method may comprise: initializing, by a process spawned by a kernel of an operating system running on a computer system, a system call filter inhibiting at least one type of application binary interface (ABI) calls; receiving a system call issued by a user space program executed by the computer system; intercepting the system call by the system call filter; determining that the system call is disabled by the system call filter; and performing a pre-determined action with respect to the system call.
    Type: Application
    Filed: August 2, 2013
    Publication date: February 5, 2015
    Applicant: Red Hat, Inc.
    Inventors: Paul Moore, Dan Walsh, Lennart Poettering
  • Secure Network Labeling to Control Inter-Process Communications in a Multi-Tenant Platform-as-a-Service (PaaS) System
    Publication number: 20150012962
    Abstract: Implementations for secure network labeling to control inter-process communications in a multi-tenant Platform-as-a-Service (PaaS) system are disclosed. A method of the disclosure includes initializing, by a processing device of a node, a gear of an application on the node, wherein the node hosts a plurality of gears for a plurality of applications of a multi-tenant Platform-as-a-Service (PaaS) system, and wherein the plurality of applications comprising multi-tenant applications having different owners. The method further includes determining a user identifier (UID) of the gear, generating a custom network security label (NSL) of the gear, assigning the custom NSL to the gear, and applying the custom NSL to an outgoing network packet sent from the gear to another gear within the PaaS system.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 8, 2015
    Inventors: Daniel Walsh, Paul Moore
  • System and method for identification of media sheet size
    Patent number: 8919770
    Abstract: A printer extracts a media sheet from a plurality of media sheets in a media supply and moves the media sheet along a media path. A plurality of sensors on the media path generate signals as the media sheet moves past the sensors, and the printer identifies a cross-process direction dimension of the media sheet with references to signals generated by the sensors. The printer identifies the dimension of the print medium without requiring media size sensors in the media supply.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: December 30, 2014
    Assignee: Xerox Corporation
    Inventors: Frederick T. Mattern, Brent Rodney Jones, Joseph Michael Ferrara, Adam Douglas Ledgerwood, Donald Richard Fess, Kenneth Paul Moore, Arthur Kahn, Gordon Byron Reid
  • Dental bur storage device
    Patent number: 8911233
    Abstract: The present invention is directed towards a dental bur storage device having a plurality of dental bur receiving holes capable of retaining a plurality of different dental bur types having different shank diameters, wherein, each of the plurality of dental bur receiving holes is tapered to allow a retaining fit to be established with any one of the plurality of different dental bur types having different shank diameters. The advantage of using a receiving hole that has a tapered form is that different types of dental burs having different diameters of shanks may be retained by the receiving holes in the dental bur storage device. This allows a wide range of different brands and different types of dental burs to be accommodated on one single dental bur storage device which greatly simplifies the process of selecting a dental bur for a dentist, particularly during a dental treatment.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: December 16, 2014
    Assignee: Gate Dental Services Limited
    Inventor: Paul Moore
  • Antibodies Reactive with B7-H3 and Uses Thereof
    Publication number: 20140328750
    Abstract: The present invention relates to antibodies that are immunoreactive to the mammalian, and more particularly, the human B7-H3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized B7-H3-reactive antibodies that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers.
    Type: Application
    Filed: July 15, 2014
    Publication date: November 6, 2014
    Applicant: MACROGENICS, INC.
    Inventors: Leslie S. Johnson, Ling Huang, Paul A. Moore, Deryk T. Loo, Francine Z. Chen
  • Latch assembly
    Patent number: 8876176
    Abstract: A latch assembly includes a chassis, a latch bolt moveably mounted on the chassis and having a closed position for retaining a striker and an open position for releasing the striker, a pawl having an engaged position at which the pawl is engaged with the latch bolt to hold the latch bolt in the closed position and a disengaged position at which the pawl is disengaged from the latch bolt, thereby allowing the latch bolt to move to the open position, an eccentric arrangement defining an eccentric axis and a pawl axis remote from the eccentric axis. The eccentric arrangement is rotatable about the eccentric axis, and the pawl is rotatable about the pawl axis. When the pawl moves from the engaged position to the disengaged position, the eccentric arrangement rotates in one of a clockwise and a counter-clockwise direction about the eccentric axis.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: November 4, 2014
    Assignee: Inteva Products, LLC
    Inventors: Nigel V. Spurr, Gurbinder Singh Kalsi, Chris Rhodes, Robert Frank Tolley, David Peatey, Robert James Clawley, Paul Moore, Jean-Vincent Olivier, Sylvain Remi Chonavel, Denis Cavallucci
  • METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
    Publication number: 20140314768
    Abstract: Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 23, 2014
    Applicant: CELERA CORPORATION
    Inventors: Steve RUBEN, Karen VAN ORDEN, Bruno DOMON, Candy LEE, Tao HE, Mehdi MESRI, Elizabeth JOSELOFF, Katherine MCKINNON, Paul MOORE, Charles BIRSE
  • VEHICLE TRANSMISSION SYSTEM AND VEHICLE DRIVE SYSTEM COMPRISING THE SAME
    Publication number: 20140283646
    Abstract: A transmission system for a hybrid vehicle is disclosed. The system includes a primary input shaft for receiving drive from a primary vehicle drive motor, such as an internal combustion engine. A secondary input shaft receives drive from a secondary vehicle drive motor, such as an electric motor. An output shaft of the system is connected to drive a final drive unit. A multi-speed gearbox is provided to connect the primary input shaft to the output shaft at one of a plurality of gear ratios. There is provided an input selection mechanism which, in a first configuration, connects the secondary input shaft to drive the output shaft and, in a second mode, connects the secondary input shaft to drive the primary input shaft. A clutch may be provided that can selectively connect or disconnect drive between the primary drive motor and the gearbox.
    Type: Application
    Filed: July 11, 2012
    Publication date: September 25, 2014
    Inventors: Adrian Paul Moore, Clive David Woolmer, Christopher Guy Cholmeley, Michael John Allen, Matthew Charles Clutterbuck, Paul Pomfret