Abstract: A cloud-based platform for zero trust network access (ZTNA) services provides zero trust network access as a service for multiple customers in a multi-tenant architecture. In this context, the configuration for a new ZTNA application is validated with a service proxy in a sandbox or similar environment before release by the cloud-based platform for access through a public network. As a significant advantage, this approach mitigates inadvertent conflicts or instability in a service proxy that supports other applications and customers.

Abstract: A cloud-based platform for zero trust network access (ZTNA) services provides zero trust network access as a service for multiple customers in a multi-tenant architecture. In this context, the configuration for a new ZTNA application is validated with a service proxy in a sandbox or similar environment before release by the cloud-based platform for access through a public network. As a significant advantage, this approach mitigates inadvertent conflicts or instability in a service proxy that supports other applications and customers.

Abstract: In an embodiment, a method includes receiving a data packet with a quality-of-service (QoS) factor to be transmitted to an endpoint device, identifying a bonding group including multiple channels of dominant and remaining channels with each channel having respective queues, and determining queue occupancies for queues associated with the channels. The queues correspond to the QoS factor. The method also includes retrieving weights corresponding the QoS factor that are associated with the channels from a weight table. The weights are calculated based at least in part on a saturation threshold of the dominant channels. The method further includes generating adjusted queue occupancies based on the queue occupancies and the weights, selecting a first queue associated with a first channel based on the adjusted queue occupancies, and scheduling the first data packet for transmitting to the endpoint device via the first queue.

Abstract: A pessary system for providing pelvic floor support for USL and other ligaments. The pessary has an elongated probe with independently inflatable balloons each located substantially the same distance from the insertion end of the probe and which inflate into separate radial sectors. The probe can be inserted into a vaginal cavity and the balloons inflated provide mechanical support to the USLs. Independent inflation of each balloon allows the mechanical USL support provided to be varied on left and right sides to compensate for differences in the degree of degradation and positioning of the USL ligaments on either side.

Abstract: Techniques are described herein for distributing power using a disaggregated solid state power distribution system. The disaggregated solid state power distribution system includes an alternating-current-to-direct-current (AC-to-DC) converter and a solid state direct-current (DC) transformer. The AC-to-DC converter converts an alternating-current (AC) voltage, which is included in an incoming AC power signal having a power of at least one megawatt from an electrical source, to an intermediate DC voltage. The AC voltage is greater than or equal to 1000 volts root-mean-square (RMS). The intermediate DC voltage is greater than or equal to 1000 volts. The solid state DC transformer provides a DC power signal to information technology (IT) hardware by transforming the intermediate DC voltage to a transformed DC voltage that is included in the DC power signal. The transformed DC voltage is less than 1000 volts.

Abstract: The disclosure provides a method of treating a hepatocellular carcinoma with a combination of a LAG-3 antagonist, a PD-1 pathway inhibitor, and an anti-angiogenesis agent.

Abstract: A method for on-demand cell site inventory update retrieval in a telecommunications carrier network comprises receiving, by an inventory application, updated component data associated with one or more components in a cell site, wherein the updated component data comprises a most up-to-date version of data describing the one or more components, storing, in a memory, a master inventory including data regarding a plurality of components in each of the cell sites in the RAN, and updating, by the inventory application, in the master inventory, records associated with each of the one or more components to include the updated component data when the master inventory excludes the updated component data associated with the one or more components.

Abstract: A system for a blockchain-based platform that integrates oral health monitoring, personalized preventive care, and data monetization. The system for blockchain-based platform comprises a computing device that has a processor and a memory for storing one or more instructions executable by the processor. The computing device is in communication with a server via a network. The system is designed to reduce dental healthcare expenses by promoting preventive care and enabling the monetization of the oral health data, and the clinical-grade data. The system facilitates user ownership, transparency, and control over personal dental health records, offering options for users to monetize the oral health data, and the clinical-grade data. The system integrates the subscriber-controlled digital wallet to ensure guaranteed oral health services.

Abstract: Playback devices comprising a network interface, an optional speaker(s), and one or more processors are disclosed herein. In some embodiments, the playback device is configured to communicate with a computing system that stores configuration data corresponding to each of a plurality of users. The playback device detects one or more users near the playback device and retrieves user configuration data corresponding to each of the one or more detected users, and thereafter, uses the user configuration data of the one or more detected users to process voice commands, play media content, and/or perform other voice and/or media related functions.

Abstract: An apparatus for cutting electrode sheets includes a conveyor and a laser device. The conveyor is configured to move an original sheet including an electrode portion and an ear portion extending from an edge of the electrode portion. The laser device is configured to move a laser to cut out a tab connected to the electrode portion from the ear portion of the original sheet. The laser device is also configured to move the laser from one edge of the electrode portion to another edge of the electrode portion to cut and separate a respective electrode sheet including the tab from the original sheet. The laser is configured to cut out the tab from the ear portion and cut and separate the respective electrode sheet including the tab from the original sheet as the conveyor is moving the original sheet.

Abstract: A compound of formula (I): wherein R3, R4, R5, R6, Z1, Z2 and T are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: The invention provides a method of treating a colorectal carcinoma with a combination of an anti-LAG-3 antibody and an anti-PD-1 or anti-PD-L1 antibody. In some aspects, the combination comprises 480 mg of each antibody such as, for example, 480 mg of an anti-LAG-3 antibody (e.g, relatlimab) and 480 mg of an anti-PD-1 antibody (e.g, nivolumab). In some aspects, the colorectal carcinoma is unresectable, advanced, or metastatic, including, for example, microsatellite stable or high microsatellite instable colorectal carcinoma.

Abstract: A cloud-based platform for zero trust network access (ZTNA) services provides zero trust network access as a service for multiple customers in a multi-tenant architecture. In this context, the configuration for a new ZTNA application is validated with a service proxy in a sandbox or similar environment before release by the cloud-based platform for access through a public network. As a significant advantage, this approach mitigates inadvertent conflicts or instability in a service proxy that supports other applications and customers.

Abstract: A ridge vent panel configured for installation over a peak of a roof comprises two longitudinal edges; two lateral sides; a ridge vent interior section bounded by the two longitudinal edges and the two lateral sides; two longitudinal series of vent openings provided along and proximate the respective two longitudinal edges; and a ridge cap supporting section. The ridge cap supporting section is provided in the ridge vent interior section between the two longitudinal series of vent openings, the ridge cap supporting section. The ridge cap supporting section comprises a ridge cap supporting section central region provided between two ridge cap supporting section edge regions. On average the ridge cap supporting section central region has a smaller thickness than the two ridge cap supporting section edge regions.

Abstract: The present disclosure is directed to one or more embodiments of mailer package assemblies including a fixed release liner and a mailer package. The fixed release liner is removably or detachably coupled to the mailer package by an adhesive layer. The fixed release liner includes one or more wickets (e.g., openings) such that the fixed release liner may be mounted to a wall by inserting fasteners (e.g., tack(s), pin(s), etc.) into the openings. The mailer package may be removed, detached, or decoupled from the fixed release liner by pulling on the mailer package decoupling the fixed release liner from the mailer package. After the mailer package is removed, an packaging associate may place an item or product within the mailer package to be shipped to a consumer. After the mailer package is removed from the fixed release liner, the fixed release liner remains mounted to the wall.

Abstract: The specification describes a catalyst for the hydrodeoxygenation of alcohols, comprising: 0.1 to 1.5 wt % palladium; 1.0 to 5.0 wt % molybdenum; and 0.05 to 0.5 wt % tin; on a zirconia support. Also described is a method for manufacturing the catalyst and a hydrodeoxygenation process using the catalyst.

Abstract: The specification describes a zirconia support comprising ?95 wt % ZrO2, wherein: the support has a crush strength of 20 to 140 N; the support has a total pore volume of 0.10 to 0.40 mL/g when measured by N2 physisorption; the support has an acid site density of 15 to 30 ?LNH3/m2; and the support has a basic site density of 0.006 to 0.015 wt %/m2 as measured by the MBOH test. Also described is a method for producing a zirconia supporting starting from zirconia or zirconium hydroxide as raw materials.

Abstract: Power draw stabilization is provided. A target power consumption of a source load is determined. The source load is generated by electronics supplied power by a primary power source through a power rail. The power rail is coupled to a capacitor bank by a bi-directional converter configured to smooth fluctuations in power drawn from the primary power source by performing mode switch operations. The mode switch operations include, in response to the source load exceeding a target power consumption, controllably switching to a second directional mode that directs current released from the capacitor bank to the power rail. The mode switch operations further include, in response to the source load dropping below the target power consumption, controllably switching the operational mode of the bi-directional converter to a first directional mode to direct current from the power rail into the capacitor bank.

Abstract: Provided herein are indole compounds that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease

Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.