Abstract: The invention relates to an iontophoretic device for the enhanced transport of substances through the skin (1), wherein at least two electrical transportation fields (Ep, Eo) with different directions are applied. In a preferred embodiment, these field are orthogonal and parallel to the skin surface, respectively, and applied in a temporally alternating sequence. Substances are thus transported in an optimal way on their meandering paths through the stratum corneum into or out of the skin. The iontophoretic device preferably comprises an array of electrodes (11) to which either a spatially alternating pattern of electrical potentials can be applied or which can alternatively be divided into two groups of neighboring electrodes that are connected to the same potential. The iontophoretic device may particularly be integrated into any skin-contacting device e.g. an electrical shaver.

Abstract: The invention relates to a shaver (1), comprising a handle (2), at least two rotary shaving heads (5), driven by at least one drive shaft (15; 115; 215) which protrudes from said handle (2), and a support structure (6) for supporting said shaving heads (5) onto the handle (2) so as to have their joined shaving surface (S) extend substantially perpendicular to said at least one drive shaft (15; 115; 215). The support structure (6) is configured such, that a space (A), restricted at one side by the shaving heads (5) and at the opposite side by the handle (2), is substantially open to its remaining, surrounding side.

Abstract: A method and system for facilitating peer-to-peer networking among local peers are described. Hashes are generated from a digital content file and virtual coordinates of virtual nodes in a virtual coordinate system. The generated hashes are then used to retrieve peer connection information.

Abstract: The present invention discloses a device and a method for controlling growth of hair on human skin with low doses of electromagnetic radiation, and a device for carrying out the method. In the method, radiation of a suitable spectrum is applied to the skin, in one or more pulses of between 1 and 100 ms, and with maximum fluencies on the skin between 1 and 12 J/cm2. By applying such low fluencies and at controlled pulse durations, follicles of the hairs are induced to the catagen phase. This means that the growth of the hairs of those follicles will stop. Although the method is not primarily aimed at immediate hair removal, hairs may be shed subsequently. In any case, further growth may be stopped for prolonged periods of time. The main advantage of the method is that the risk of damage to the skin is minimized.

Abstract: Systems and methods for achieving sub-surface, highly spatially selective cardiac ablation by means of laser induced optical breakdown (LIOB) are disclosed. Damage to non-targeted heart and artery/vein tissue is to be minimized according to the present disclosure. A catheter enters the heart, e.g., via a vein, and catheter location is determined/confirmed. Laser pulses are guided through the optical path within the catheter and, at or near the catheter end, a focusing structure is provided that focuses the laser radiation through the non-targeted vein/heart tissue into the targeted tissue. In the focusing structure, laser induced LIOB occurs and related mechanical effects affect the targeted tissue.

Abstract: The invention is directed to a process and a system to compress air. The process involves the following steps, (i) compressing air in a compressor, (ii) cooling the compressed air as obtained in step (i) (iii) further compressing the air of step (ii) in a second compressor, (iv) further compressing at least part of the compressed air as obtained in step (iii) in a booster compressor, wherein the compressor in step (i) is an axial compressor, the compressor of step (i) and (iii) are driven by a common first driver and the booster compressor is driven by a separate second driver and wherein the compressors of steps (i) and (iii) are split into two individual casings.

Abstract: The invention relates to a device (1) for treating human skin by means of radiation. The device comprises a housing (3) with a radiation exit opening (13). A radiation source (9) is accommodated in the housing. Radiation generated by the radiation source propagates from the radiation source towards the radiation exit opening via a radiation path (15) comprising a radiation filter having a predetermined transmission spectrum. According to the invention the radiation filter comprises a reflecting surface (23) via which the radiation propagating along the radiation path (15) is reflected. The reflecting surface has a coating which provides the reflecting surface with a reflection spectrum substantially matching the predetermined transmission spectrum. An advantage is that the reflection surface can be optimally and uniformly cooled, so that the heat generated as a result of the absorption of part of the radiation by the radiation filter can be effectively transmitted to a cooling system (25) of the device (1).

Abstract: The invention relates to a device (1) for removing hair (46) from skin (30), comprising an optical hair cutting device(12, 14, 20), and a hair and debris removing system. The hair removing system comprises a remover part (36) that mechanically engages the hair (46) in order to remove it after severing, or cutting. The use of mechanical engaging has the advantage that the optical contactless severing method, which by itself is not capable of removing hairs after cutting, is assisted in actual removing the hairs. The debris removing system may comprise a brush (36), a tape or fluid dispenser, etc., and may be assisted by a suction device (48).

Abstract: Apparatus for use in managing disk drive spinup includes a plurality of disk drives newly inserted into a data storage system enclosure that is in an already powered up steady state. The apparatus also includes first and second control cards in the enclosure, and first control logic operable to cause the first and second control cards to coordinate to cause the disk drives to spin up in stages.

Abstract: A device and a method for applying hair dye to hair. The device comprises a housing, a reservoir for said hair dye, at least one opening for said hair dye to pass through, and means for moving the hair dye from said reservoir to the hair via said at least one opening for the hair dye, wherein first heating means are provided for heating the hair dye before said hair dye passes through said at least one opening for the hair dye. The method comprises the heating of the hair dye prior to the application of the hair dye to the hair.

Abstract: A data processor comprises a number of databases for storing records and a plurality of user systems capable of accessing the databases. The user systems each include a datastore/application environment instance with which users can interface. Host systems may include more than one instance. The datastores contain time-versioned views of records. The data processor is operable in at least two modes, a normal operation mode in which an evaluation in response to a user enquiry can be carried out using records relevant to a current viewpoint time and time span, and a recovery operation mode in which records relevant to a viewpoint time and time span for a previous evaluation are accessed and used to exactly reproduce the previous evaluation.

Abstract: A device and a method for applying hair dye to hair. The device comprises a housing, a reservoir for said hair dye, at least one opening for said hair dye to pass through, and means for moving the hair dye from said reservoir to the hair via said at least one opening for the hair dye, wherein first heating means are provided for heating the hair dye before said hair dye passes through said at least one opening for the hair dye. The method comprises the heating of the hair dye prior to the application of the hair dye to the hair.

Abstract: A data processor comprises a number of databases for storing records and a plurality of user systems capable of accessing the databases. The user systems each include a datastore/application environment instance with which users can interface. Host systems may include more than one instance. The datastores contain time-versioned views of records. The data processor is operable in at least two modes, a normal operation mode in which an evaluation in response to a user enquiry can be carried out using records relevant to a current viewpoint time and time span, and a recovery operation mode in which records relevant to a viewpoint time and time span for a previous evaluation are accessed and used to exactly reproduce the previous evaluation.

Abstract: A data processing method evaluates expressions, including temporally-scoped operands, to produce temporally-scoped results. Each of the temporally-scoped operands and results includes a sequence of one or more value instances, each value instance including a data item, a start time, and an end time, the start time and end time defining a time span in which the data item is valid. An expression involving a binary operator is evaluated by scanning each of the operands of the binary operator and generating a value instance in the result, in respect of each time span in which each operand has a constant value.

Abstract: In a time-versioned storage mechanism, data is stored as a plurality of records, each including at least one attribute, a time span indicating the time span for which the attribute is valid, an insertion time indicating when the record was created, and a type field. The type field indicates whether the record is a concrete record, a delta record that possibly modifies the attribute value of a previous concrete or delta record, or an archive record replacing one or more records that have been archived. The data is accessed to find an attribute value from the point of view of a specified viewpoint time, by retrieving only records with insertion times not later than said viewpoint time, and constructing an attribute value from the retrieved records. The data is updated only by adding concrete records or delta records, without modifying attribute values in the concrete records or delta records.

Abstract: A method for evaluating an expression comprises issuing parallel requests to acquire a plurality of operands. If, upon receipt of a first subset of the operands, it is determined that a second subset of the operands is no longer required in respect of a particular time span, the request for the second subset cancelled for that particular time span. If one operand contains an error indication for a particular time span, the method continues with the request for the other operand for that particular time span, and returns an “error” for that particular time span only if the request for the other operand is not cancelled.

Abstract: The invention relates to a composition, solution, and method for delivering desired substances into the cytosol of living eucaryotic cells. The composition includes a poly(ethylene glycol) component having a designated molecular weight in the range between about 300 and about 900 daltons, and a carbohydrate component which is membrane impermeable and water soluble. The osmotic delivery solution delivers reporter-tagged molecules and complexes, drugs, antisense and antigene oligos, RNAs, DNAs, peptides, proteins, carbohydrates, and the like into cultured cells using an improved osmotic delivery method. The method may also be used for extracorporal therapy. In a particularly preferred embodiment of extracorporal therapy, the desired substance delivered into the cytosol of the cells is a Morpholino antisense oligo.