Abstract: A method and apparatus for modifying data synchronization of a portable computing device responsive to movement of the portable computing device are disclosed. Data exchange quality associated with multiple locations is captured and stored. A predicted location of a portable computing device is determined from stored data describing previous locations of the portable computing device or navigation data. Data exchange quality associated with the predicted location is retrieved and analyzed to modify data exchange between the portable computing device and a server. For example, if the data exchange quality of the predicted location is low, a fault-tolerant data exchange method is selected or if data exchange is not possible at the predicted location, data exchanges occur more frequently prior to the portable computing device reaching the predicted location.

Abstract: A high-speed optical interface for connecting computers to external I/O devices allows a number of native I/O formats to be encapsulated into PCIe Vendor Defined Messages (“VDMs”) for transfer over a single physical medium, preferably optical, and is thus referred to as the converged I/O (“CIO”) interface. Standard PCIe bridges are modified to support peer-to-peer communications, allowing greater exploitation of the capabilities of PCIe.

Abstract: The invention is directed toward improvements in security substrates, such as paper, used for making security documents, such as bank notes, having anti-counterfeit able features and in particular to security substrates incorporating an elongate security element and methods of making the substrate. The invention comprises a security substrate for making security documents and the like comprising a fibrous base substrate and an elongate security element at least partially embedded therein. At one surface of the security substrate one portion of the security element is exposed to provide a continuous track along the length of the security element. A plurality of other portions along at least one edge of the security element are partially covered by overlapping regions of the fibrous substrate. The invention further comprises a method of manufacturing such a security substrate.

Abstract: The invention relates to databases of T cell epitopes, especially helper T cell epitopes, for rapid interrogation of protein sequences for the presence of T cell epitopes. The invention includes full or partial databases and data structures of T cell epitopes including epitopes identified especially by ex vivo T cell assays with test peptides and includes T cell epitopes identified by extrapolation of data from test peptides. The present invention also includes high throughput methods for determining the T cell epitope activity of peptides for subsequent inclusion in databases and data structures including methods where subsets of T cell especially regulatory T cells are removed or inhibited from T cell assays in order to maximize the sensitivity of detection of T cell epitope activity.

Abstract: Circuits, methods, and apparatus that provide for the powering of active components in connector inserts at each end of a cable may in various ways. For example, where a host is coupled to a device that is not self-powered, the host may provide power for circuitry at each end of the cable. In various embodiments of the present invention, the device may request higher voltage from the host, such that more power can be delivered. In these cases, the device may regulate the voltage received from the host to a lower voltage, and then provide the lower voltage to circuitry at one or both ends of the cable. Where the host is connected to a device that is self-powered, the host and the self-powered device may power their respective connector insert circuits.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: The present application relates to compositions of modified toxins exhibiting reduced immunogenicity and reduced binding to vascular endothelium or vascular endothelial cells, thereby reducing the incidence of Vascular Leak Syndrome. Also provided are polypeptide toxophores from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope. Another aspect relates to a polypeptide toxophore from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope and at least one amino acid residue of at least one VLS motif of an unmodified native diphtheria toxin. Another aspect relates to a fusion protein which comprises a modified diphtheria toxin and a non-diphtheria toxin fragment that is a cell binding portion. Another aspect relates to the use of a modified diphtheria toxin for the treatment of a malignant disease or a non-malignant disease.

Abstract: A gaming device provides a single player poker game including one or more opportunities for forming player hands. In one embodiment, for a play of the poker game, a player places a wager on each of a plurality of player hands. The gaming device provides the player with one or more opportunities to fold one or more of the player hands and withdraw the wager associated with the folded hand. A number of community cards are dealt. The gaming device determines and provides any awards associated with a ranking of each of the remaining player hands according to a paytable.

Abstract: An occupant protection apparatus comprises an inflatable airbag with a panel, the panel including a first vent opening that permits inflation fluid to escape out of the airbag; and a valve sheet including a second vent opening movable relative to the first vent opening, the valve sheet having opposite ends that are each fixed to a surface of the airbag. One end of the valve sheet moves with the panel during inflation of the airbag to move the second vent opening relative to the first vent opening. The apparatus also includes a valve guide or envelope to guide movement of the valve sheet relative to the panel, the valve sheet is capable of sliding between the valve guide and the panel. Both ends of the valve sheet remain fixed to the panel during and after inflation of the airbag. The valve sheet includes a tear tab to temporarily retain the valve sheet to the panel.

Abstract: A gaming device includes a single player poker game that includes one or more opportunities for selecting or forming player hands. In one embodiment, wagers are placed on several player hands, and the gaming device matches these wagers for each of several dealer hands. A play of the game includes one or more opportunities for a player to fold or cancel one of the player hands and withdraw the wager associated with the withdrawn hand. The gaming device may also cause one or more of the dealer hands to be folded. In another embodiment, the game includes dealing several initial player hands and enabling a player to select one of the player hands to compete against one or more dealer hands. In another embodiment, a play of the game includes dealing a plurality of player cards and enabling a player to form multiple player hands from the dealt player cards. The game also includes dealing a plurality of dealer cards and forming multiple dealer hands from the dealt dealer cards.

Abstract: Circuits, methods, and apparatus that provide for the powering of active components in connector inserts at each end of a cable may in various ways. For example, where a host is coupled to a device that is not self-powered, the host may provide power for circuitry at each end of the cable. In various embodiments of the present invention, the device may request higher voltage from the host, such that more power can be delivered. In these cases, the device may regulate the voltage received from the host to a lower voltage, and then provide the lower voltage to circuitry at one or both ends of the cable. Where the host is connected to a device that is self-powered, the host and the self-powered device may power their respective connector insert circuits.

Abstract: A heat exchanger (10) has an outer housing (16) and a first helical fluid flow path or coil (12) located in the housing (16) defining a plurality of turns and having an inlet (24) and an outlet (22) for entry and exit of fluid into the flow path to be heated or cooled. A second helical coil (14) defining a second fluid flow path is located within the housing (16) adjacent to the first coil. The second coil also has an inlet (24) and outlet (22) for a passage for hot or cold service media. A conductive or non-conductive sheath (18) is disposed between the coils. A transfer medium is disposed in the housing for transfer of heat between the first and second flow paths. A plurality of baffles (20) are located between the outer housing and sheath and disposed between turns of the first coil. A plurality of baffles (21) are also disposed between turns of the second coil (14).

Abstract: An occupant protection apparatus comprises an inflatable airbag with a panel, the panel including a first vent opening that permits inflation fluid to escape out of the airbag; and a valve sheet including a second vent opening movable relative to the first vent opening, the valve sheet having opposite ends that are each fixed to a surface of the airbag. One end of the valve sheet moves with the panel during inflation of the airbag to move the second vent opening relative to the first vent opening. The apparatus also includes a valve guide to guide movement of the valve sheet relative to the panel, the valve sheet is capable of sliding between the valve guide and the panel. Both ends of the valve sheet remain fixed to the panel during and after inflation of the airbag.

Abstract: Described herein are methods and devices for underwater deployment of a structure. For example, the embodiments described herein are particularly focused on sonobuoys that are configured for autonomous deployment in an underwater environment. One embodiment provides a sonobuoy having a plurality of arms, which are in some embodiments telescopic. The sonobuoy is configured such that, upon deployment in an underwater environment, the arms extend and rotate from a collapsed storage configuration to an operative configuration. The rotation is brought about by way of tension in petal lines, which extend between an innermost telescopic segment of each arm and a central tether line intermediate the arms and a buoyancy device.

Abstract: An occupant protection apparatus comprises an inflatable airbag with a panel, the panel including a first vent opening that permits inflation fluid to escape out of the airbag; and a valve sheet including a second vent opening movable relative to the first vent opening, the valve sheet having opposite ends that are each fixed to a surface of the airbag. One end of the valve sheet moves with the panel during inflation of the airbag to move the second vent opening relative to the first vent opening. The apparatus also includes a valve guide or envelope to guide movement of the valve sheet relative to the panel, the valve sheet is capable of sliding between the valve guide and the panel. Both ends of the valve sheet remain fixed to the panel during and after inflation of the airbag. The valve sheet includes a tear tab to temporarily retain the valve sheet to the panel.

Abstract: The invention relates to improvements in methods of making sheets for security documents having edge or corner reinforcing watermarks (13, 18) and a surface applied feature (15) and a method of making a sheet from a fibrous substrate, said sheet has corners and edges joined at said corners. The method comprises the step of forming the substrate by depositing fibres on a support surface and forming at least one reinforcing watermark (13, 18) at a predetermined position in the substrate. The reinforcing watermark (13, 18) increases the stiffness of the sheet in the watermarked region and is a positive watermark formed by varying the grammage of fibres of the substrate to form at least two adjacent bars (13a, 18a) of increased grammage relative to the mean grammage of fibres in adjacent areas of the substrate. At least one raised region (17) is formed by increasing the grammage of fibres, which joins the adjacent bars within the at least one reinforcing watermark to form a smooth planar surface.

Abstract: A heat exchanger (10) comprises a coolant line (11) and a beverage line (13), embedded in a solid block of Aluminium (15). The coolant line (11) is in the form of a first helical coil defining a plurality of turns typically located in the centre of the block. The beverage line (13) is in the form of a second helical coil defining a plurality of turns extending around the first coil. The coolant line defines a cold zone (12), typically in the centre of the block, with the volume outside the central zone carrying the beverage line ratio defining an designated beverage cooling zone (14). The volume ratio of the designated zone to the cold zone is about 150:100. The heat exchanger allows for cooling of beer to precise temperatures and even temperatures close to freezing point, using direct expanded Freon refrigeration methods. The complete system including the refrigeration equipment to be packaged into a small area, such as is available under bars and dispensing counters etc.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: A system for providing an iced alcoholic beverage such as iced beer or carbonated soft drink includes a source of chilled coolant (16), and a beverage line (10) for supplying the beverage. A heat exchanger (20) is disposed in the beverage line (10) for cooling the beverage by heat transfer to the chilled coolant. A restriction (22) or orifice forming a venturi is provided in the beverage line (10) downstream from the heat exchanger. A chilled font (18) for further cooling the beverage is provided downstream from the orifice. The font (18) includes a dispenser tap (30) capable of dispensing the beverage at a relatively low dispense rate and at a relatively higher dispense rate. In use the beverage is first dispensed at a relatively low dispense rate through a smaller orifice of a narrow diameter at a preset low flow rate of beverage, and becomes ice or slush (40).

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.