Patents by Inventor Paul Brennan

Paul Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic peptide ligands specific for TREM2
    Patent number: 11904020
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: February 20, 2024
    Assignee: BicycleTx Limited
    Inventors: Paul Brennan, Amy Brown, Liuhong Chen, John Davis, Yuliya Demydchuk, Donatella Di Rienzo, Ellen Gowans, Rama McCrory, Emma Mead, Emma Murphy, Mike Rigby, Michael Skynner, Tom Smith, Steven Stanway
  • Antimicrobial and antiviral sulfur containing glycerol monoester derivatives
    Patent number: 11873272
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: January 31, 2023
    Date of Patent: January 16, 2024
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Fibrous Structures and Methods for Making Same
    Publication number: 20230272585
    Abstract: Fibrous structures that exhibit a novel combination of properties and to methods for making such fibrous structures are provided.
    Type: Application
    Filed: May 5, 2023
    Publication date: August 31, 2023
    Inventors: Jonathan Paul Brennan, Steven Lee Barnholtz, Jeffrey Len Osborne, Pamela Marie Morison
  • Container for fibrous wipes
    Patent number: 11680373
    Abstract: Containers containing fibrous wipes that exhibit a novel combination of properties are provided.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: June 20, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Jonathan Paul Brennan, Steven Lee Barnholtz, Jeffrey Len Osborne, Pamela Marie Morison
  • ANTIMICROBIAL AND ANTIVIRAL SULFUR CONTAINING GLYCEROL MONOESTER DERIVATIVES
    Publication number: 20230174473
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: January 31, 2023
    Publication date: June 8, 2023
    Applicant: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Antimicrobial and antiviral sulfur containing glycerol monoester derivatives
    Patent number: 11572342
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: February 7, 2023
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • PROCESS FOR MAKING FIBROUS STRUCTURES
    Publication number: 20220325440
    Abstract: Processes for making fibrous structures and more particularly processes for making fibrous structures comprising filaments are provided.
    Type: Application
    Filed: April 26, 2022
    Publication date: October 13, 2022
    Inventors: Steven Lee Barnholtz, Paul Dennis Trokhan, Michael Donald Suer, Douglas Jay Barkey, Jonathan Paul Brennan, Ronald Thomas Gorley
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2
    Publication number: 20220296726
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TREM2. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder mediated by TREM2.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 22, 2022
    Applicant: BicycleTx Limited
    Inventors: Paul Brennan, Amy Brown, Liuhong Chen, John Davis, Yuliya Demydchuk, Donatella Di Rienzo, Ellen Gowans, Rama McCrory, Emma Mead, Emma Murphy, Mike Rigby, Michael Skynner, Tom Smith, Steven Stanway
  • Antimicrobial and antiviral sulfur containing glycerol monoester derivatives
    Patent number: 11365176
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: January 6, 2022
    Date of Patent: June 21, 2022
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Process for making fibrous structures
    Patent number: 11326276
    Abstract: Processes for making fibrous structures and more particularly processes for making fibrous structures comprising filaments are provided.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: May 10, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Steven Lee Barnholtz, Paul Dennis Trokhan, Michael Donald Suer, Douglas Jay Barkey, Jonathan Paul Brennan, Ronald Thomas Gorley
  • ANTIMICROBIAL AND ANTIVIRAL SULFUR CONTAINING GLYCEROL MONOESTER DERIVATIVES
    Publication number: 20220127224
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: January 6, 2022
    Publication date: April 28, 2022
    Inventors: Dayton T. Reardan Ph.D., Paul Brennan, Patrick Schlievert
  • ANTIMICROBIAL AND ANTIVIRAL SULFUR CONTAINING GLYCEROL MONOESTER DERIVATIVES
    Publication number: 20220089535
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 24, 2022
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Dissolvable fibrous web structure article comprising active agents
    Patent number: 11142848
    Abstract: The personal care compositions of the present invention are in the form of an Article comprising a dissolvable fibrous web structure. The fibers of the dissolvable fibrous web structure comprise a surfactant; a water soluble polymeric structurant; and a plasticizer. Additionally the ratio of the water soluble water soluble polymeric structurant to the active agent in the fiber is 3.5 or less.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: October 12, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Robert Wayne Glenn, Jr., Rajeev Chhabra, William Maxwell Allen, Jr., Jonathan Paul Brennan
  • SOFT TISSUE IMPLANT POCKET
    Publication number: 20210069374
    Abstract: There is provided a soft tissue implant pocket which reduces the incidence of capsular contracture. The pocket is manufactured from a biodegradable, biocompatible polyurethane foam. The polyurethane contains biodegradable polyols and the foam has a pore size configured for cellular infiltration. The soft tissue implant pocket find use in, for example, breast augmentation and reconstruction.
    Type: Application
    Filed: December 21, 2018
    Publication date: March 11, 2021
    Inventors: Paul BRENNAN, Timothy Graeme MOORE
  • Fibrous Structures and Methods for Making Same
    Publication number: 20200325631
    Abstract: Fibrous structures that exhibit a novel combination of properties and to methods for making such fibrous structures are provided.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 15, 2020
    Inventors: Jonathan Paul Brennan, Steven Lee Barnholtz, Jeffrey Len Osborne, Pamela Marie Morison
  • Fibrous structures and methods for making same
    Patent number: 10697127
    Abstract: Fibrous structures that exhibit a novel combination of properties and to methods for making such fibrous structures are provided.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: June 30, 2020
    Assignee: The Procter & Gamble Company
    Inventors: Jonathan Paul Brennan, Steven Lee Barnholtz, Jeffrey Len Osborne, Pamela Marie Morison
  • Process for Making Fibrous Structures
    Publication number: 20200102671
    Abstract: Processes for making fibrous structures and more particularly processes for making fibrous structures comprising filaments are provided.
    Type: Application
    Filed: December 4, 2019
    Publication date: April 2, 2020
    Inventors: Steven Lee Barnholtz, Paul Dennis Trokhan, Michael Donald Suer, Douglas Jay Barkey, Jonathan Paul Brennan, Ronald Thomas Gorley
  • DISSOLVABLE FIBROUS WEB STRUCTURE ARTICLE COMPRISING ACTIVE AGENTS
    Publication number: 20200071851
    Abstract: The personal care compositions of the present invention are in the form of an Article comprising a dissolvable fibrous web structure. The fibers of the dissolvable fibrous web structure comprise a surfactant; a water soluble polymeric structurant; and a plasticizer. Additionally the ratio of the water soluble water soluble polymeric structurant to the active agent in the fiber is 3.5 or less.
    Type: Application
    Filed: November 5, 2019
    Publication date: March 5, 2020
    Inventors: Robert Wayne Glenn, JR., Rajeev Chhabra, William Maxwell Allen, JR., Jonathan Paul Brennan
  • Process for making fibrous structures
    Patent number: 10513801
    Abstract: Processes for making fibrous structures and more particularly processes for making fibrous structures comprising filaments are provided.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: December 24, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Steven Lee Barnholtz, Paul Dennis Trokhan, Michael Donald Suer, Douglas Jay Barkey, Jonathan Paul Brennan, Ronald Thomas Gorley
  • Support column
    Patent number: D967986
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: October 25, 2022
    Assignee: PROPERTY TRADING GROUP PTY LIMITED
    Inventor: James Paul Brennan