Patents by Inventor Paul C. DiCesare

Paul C. DiCesare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6516953
    Abstract: A device and method is provided for separating components of a fluid sample. The device includes a plurality of constituents comprising a container, a liner in the container, a closure for the container and a composite element. The composite element is a seal plug with a density between the densities of the components of the fluid sample is releasably engaged with the container closure and with the liner. A needle cannula is used to deposit a fluid sample in the liner and the entire device is placed in a centrifuge. The centrifugal load causes the seal plug to separate from the closure and causes the liner to expand outwardly against the container. The seal plug migrates into the fluid sample and stabilizes between the densities of the components of the fluid sample. The liner will resiliently return to its initial configuration upon termination of centrifugal load such that the liner sealingly engages the seal plug and separates the components of the fluid sample.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: February 11, 2003
    Assignee: Becton, Dickinson and Company
    Inventors: Paul C. DiCesare, Jeffrey Karg, Fu-Chung Lin, Jeffrey P. Radziunas
  • Publication number: 20030023251
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device. an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery. particularly in port-access CABG surgery,. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member. forming the attachment with the target vessel wall and a coupling member. forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member. with the graft vessel attached. into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: June 20, 2002
    Publication date: January 30, 2003
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6491705
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: December 10, 2002
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6491704
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: December 10, 2002
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6471069
    Abstract: A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a flexible collapsible inner container disposed within a substantially rigid outer container. A closure seals the open top end of the outer container. A filter assembly is sealingly mounted to the open top end of the inner container. The filter assembly includes a filter that permits lighter fractions to pass therethrough, while substantially blocking the heavier fractions. The filter assembly further includes a filter support having a slit valve registered with the filter. The slit valve opens in response to fluid pressure created by the lighter fractions for permitting the lighter fractions to flow therethrough.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: October 29, 2002
    Assignee: Becton Dickinson and Company
    Inventors: Fu-Chung Lin, Paul C. DiCesare, Jeffrey Radziunas
  • Publication number: 20020151914
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: June 19, 2002
    Publication date: October 17, 2002
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20020131904
    Abstract: A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly an elastic portion and a plug member. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the elastic portion of the separator to deform so that the separator migrates into the fluid sample and stabilizes between the heavier and lighter fractions of the fluid sample. The elastic portion of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the elastic portion sealingly engages the container and separates the heavier and lighter fractions of the fluid sample.
    Type: Application
    Filed: May 13, 2002
    Publication date: September 19, 2002
    Applicant: Becton Dickinson and Company
    Inventors: Paul C. DiCesare, Richmond Cohen
  • Patent number: 6451034
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: September 17, 2002
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6443965
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: September 3, 2002
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20020094305
    Abstract: A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising a deformable bellows, a ballast mounted to the lower end of the bellows, and a float is engageable with an upper end of the bellows. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the ballast to move toward the bottom of the tube and causes an elongation and narrowing of the bellows. The separator then moves down the tube and stabilizes in a position between the separated phases of the fluid sample. Termination of the centrifugal load enables the bellows to return to its original condition in sealing engagement with the walls of the tube.
    Type: Application
    Filed: November 30, 2000
    Publication date: July 18, 2002
    Inventors: Paul C. Dicesare, Jeffrey R. Radziunas, Robert Losada, Fu-Chung Lin
  • Publication number: 20020087175
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device. an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: September 28, 2001
    Publication date: July 4, 2002
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6406671
    Abstract: A device and method is provided for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly an elastic portion and a plug member. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the elastic portion of the separator to deform so that the separator migrates into the fluid sample and stabilizes between the heavier and lighter fractions of the fluid sample. The elastic portion of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the elastic portion sealingly engages the container and separates the heavier and lighter fractions of the fluid sample.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: June 18, 2002
    Assignee: Becton, Dickinson and Company
    Inventors: Paul C. DiCesare, Richmond Cohen
  • Publication number: 20020064484
    Abstract: A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a flexible collapsible inner container disposed within a substantially rigid outer container. A closure seals the open top end of the outer container. A filter assembly is sealingly mounted to the open top end of the inner container. The filter assembly includes a filter that permits lighter fractions to pass therethrough, while substantially blocking the heavier fractions. The filter assembly further includes a filter support having a slit valve registered with the filter. The slit valve opens in response to fluid pressure created by the lighter fractions for permitting the lighter fractions to flow therethrough.
    Type: Application
    Filed: November 30, 2000
    Publication date: May 30, 2002
    Inventors: Fu-Chung Lin, Paul C. DiCesare, Jeffrey Radziunas
  • Patent number: 6387105
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: May 14, 2002
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6371965
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: April 16, 2002
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20020029050
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: July 26, 2001
    Publication date: March 7, 2002
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20020029049
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: July 26, 2001
    Publication date: March 7, 2002
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20020019643
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: September 20, 2001
    Publication date: February 14, 2002
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Publication number: 20010047179
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery . particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Application
    Filed: July 26, 2001
    Publication date: November 29, 2001
    Inventors: Hanson S. Gifford, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 6267772
    Abstract: An implantable prosthesis for occluding the opening of a muscle or tissue defect. The implant is laparoscopically deliverable with a system for loading and delivering the prosthesis through a trocar cannula. The prosthesis includes an implantable material with a body portion sufficient to extend across and occlude a defect opening. Antimigration barbs extend from the implantable material to prevent migration of the prosthesis after implantation. A semi-rigid ring may be attached to the material for supporting the body portion. The barbs may be located on the ring. The implantable prosthesis may be provided with a sufficient hoop strength to prevent the body portion from collapsing into the defect opening.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: July 31, 2001
    Assignee: C. R. Bard, Inc.
    Inventors: Paul J. Mulhauser, Paul C. DiCesare