Patents by Inventor Paul Glyn Jones
Paul Glyn Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220389506Abstract: The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.Type: ApplicationFiled: June 28, 2021Publication date: December 8, 2022Applicant: MARS, INCORPORATEDInventors: Alan James Martin, Paul Glyn Jones, Adrian Watson, Jan Rothuizen, Hille Fieten, Pieter Antonius Jozef Leegwater
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Publication number: 20210298328Abstract: The presently disclosed subject matter relates to food products comprising oligosaccharides for an animal, such as a domestic animal or a pet. In certain embodiments, the food product can be a feline food product or a canine food product.Type: ApplicationFiled: August 8, 2019Publication date: September 30, 2021Applicants: MARS, INCOROPRATED, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Kevin Hughes, Carlito Lebrilla, Paul Glyn Jones, David J. Wrigglesworth
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Publication number: 20190062839Abstract: The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.Type: ApplicationFiled: November 6, 2018Publication date: February 28, 2019Applicant: MARS, INCORPORATEDInventors: Alan James Martin, Paul Glyn Jones, Adrian Watson, Jan Rothuizen, Hille Fieten, Pieter Antonius Jozef Leegwater
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Patent number: 10150997Abstract: The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287; (b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).Type: GrantFiled: December 6, 2012Date of Patent: December 11, 2018Assignee: MARS, INCORPORATEDInventors: Alan James Martin, Paul Glyn Jones, Adrian Watson, Jan Rothuizen, Hille Fieten, Pieter Antonius Jozef Leegwater
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Patent number: 9415067Abstract: The present invention provides a method of testing a dog to determine the likelihood that the dog is protected from liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: GrantFiled: September 9, 2013Date of Patent: August 16, 2016Assignee: MARS, INCORPORATEDInventors: Paul Glyn Jones, Alan James Martin
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Publication number: 20160184355Abstract: The present invention provides a method of testing a dog to determine the likelihood that the dog is protected from liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: ApplicationFiled: September 9, 2013Publication date: June 30, 2016Applicant: MARS, INCInventors: PAUL GLYN JONES, ALAN JAMES MARTIN
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Publication number: 20150374750Abstract: The present invention provides a method of testing a dog to determine the likelihood that the dog is protected from liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: ApplicationFiled: September 11, 2015Publication date: December 31, 2015Inventors: Paul Glyn Jones, Alan James Martin
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Publication number: 20140351962Abstract: The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287; (b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).Type: ApplicationFiled: December 6, 2012Publication date: November 27, 2014Applicant: MARS, INC.Inventors: Alan James Martin, Paul Glyn Jones, Adrian Watson, Jan Rothuizen, Hille Fieten, Pieter Antonius Jozef Leegwater
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Publication number: 20140093584Abstract: The present invention provides a method of testing a dog to determine the likelihood that the dog is protected from liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: ApplicationFiled: September 9, 2013Publication date: April 3, 2014Applicant: MARS, INCInventors: PAUL GLYN JONES, ALAN JAMES MARTIN
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Publication number: 20120208182Abstract: The present invention provides a method of determining the susceptibility of a dog to liver copper accumulation, comprising detecting the presence or absence in the genome of the dog of (a) a polymorphism in the GOLGA5, ATP7a or UBL5 gene that is indicative of susceptibility to liver copper accumulation and/or (b) a polymorphism in linkage disequilibrium with a said polymorphism (a). The invention also provides a method of determining the likelihood that a dog is protected from liver copper accumulation comprising detecting the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO: 142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: ApplicationFiled: October 5, 2009Publication date: August 16, 2012Inventors: Paul Glyn Jones, Alan James Martin
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Publication number: 20120040017Abstract: The present invention provides a method of testing a dog to determine the likelihood that the dog is protected from liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms in linkage disequilibrium with (a).Type: ApplicationFiled: April 7, 2010Publication date: February 16, 2012Applicant: MARS, INCInventors: Paul Glyn Jones, Alan James Martin
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Publication number: 20110021364Abstract: The invention provides a method of predicting the size of a dog that will be attained in adulthood, comprising typing the nucleotide(s) present for a single nucleotide polymorphic (SNP) marker present in the genome of the dog at a position equivalent to position 201 in one or more of the sequences identified in Table 1, and/or at one or more positions which are in linkage disequilibrium with any one of these positions, and thereby predicting the size of the dog that will be attained in adulthood.Type: ApplicationFiled: November 7, 2008Publication date: January 27, 2011Applicant: MARS, INCORPORATEDInventors: Paul Glyn Jones, Stephen Harris, Alan James Martin
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Publication number: 20100278938Abstract: The present invention provides a method of determining the susceptibility of a dog to liver copper accumulation comprising detecting the presence or absence of (a) a polymorphism in the GOLGA5, ATP7a or UBL5 gene of the dog that is indicative of susceptibility to copper accumulation and/or (b) a polymorphism in linkage disequilibrium with a said polymorphism (a), and thereby determining the susceptibility of the dog to liver copper accumulation. The invention also provides a foodstuff comprising copper at a concentration of less than 21 mg/kg dry matter for use in preventing a disease attributable to liver copper accumulation in a dog having genetic inheritance of the Labrador Retriever breed.Type: ApplicationFiled: October 3, 2008Publication date: November 4, 2010Applicant: MARS, INCInventors: Paul Glyn Jones, Alan James Martin, Gaby Hoffmann, Jan Rothuizen
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Publication number: 20080226766Abstract: A method of determining susceptibility to periodontitis in a Shih Tzu dog, Yorkshire Terrier dog or a dog of a breed that is genetically related to the Shih Tzu or Yorkshire Terrier breed, comprises: a) typing the nucleotide present in the genome of the dog at or at a position equivalent to each of the following: position 201 of SEQ ID NO: 2 (SNP_02), or a position that is in linkage disequilibrium with this position,—position 201 of SEQ ID NO: 4 (SNP_04), or a position that is in linkage disequilibrium with this position, and position 201 of SEQ ID NO: 9 (SNPJ39), or a position that is in linkage disequilibrium with this position, and b) thereby determining whether the dog is susceptible to periodontitis.Type: ApplicationFiled: September 18, 2006Publication date: September 18, 2008Applicant: MARS INCORPORATEDInventors: Neale Fretwell, James Daniel Ibbotson, Paul Glyn Jones, Alan James Martin