Abstract: A system and method for processing a plurality of medical images using a plurality of clinical applications. A current study is received by a first server, the current study having first image series metadata. The first server can determine, based on several different techniques, that the current study is in progress. The system and method generates an assembled study set comprising the current study that is processed using a clinical application, the current study having a first series and a second series.

Abstract: The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a poly(ethylene glycol) polymer; each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided.

Abstract: A shock isolator includes slots in inner and outer parts that define flexures between the parts. The slots may include inner slots and outer slots that are offset from each other around a perimeter of the inner part. The shock isolator also includes stops that provide a mechanical limit on the movement of the flexures. The stops may be posts that extend from one of the parts into holes in the other of the parts. In another embodiment that stops may be extensions from one of the parts over portions of the other of the parts. The stops help in preventing plastic bending and/or fracture of the flexures due to stress.

Abstract: Frozen un-proofed dough pieces are produced by pinching an upper skin of an un-proofed dough body to a lower skin and producing a score through the upper skin prior to freezing. The un-proofed dough pieces are formed by mass production, with an un-proofed dough sheet being cut to form dough strips which are then cut into the un-proofed dough pieces, with the score for each un-proofed dough piece being formed either before, during or after the individual un-proofed dough pieces are actually created, but before freezing.

Abstract: The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a poly(ethylene glycol) polymer, each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided.

Abstract: A method includes scanning a thickness of a workpiece in at least one point using a thickness sensor, determining that the workpiece is out of alignment in a cutting machine using the thickness sensor, and realigning the workpiece relative to the cutting machine or adjusting a machining operation using a controller of the cutting machine in response to determining that the workpiece is out of alignment.

Abstract: A bread product is produced by forming a dough piece, creating at least one score in the dough piece, applying an adhesive to the dough piece with the adhesive extending across the score, freezing the dough piece to produce a frozen dough piece, and baking the dough piece, causing the adhesive to melt while establishing a bread product having, in a central region of the bread product, what was once a score held together by the adhesive during the early stages of baking, an internal exposed region. The outlined production steps can be re-arranged, so long as the scoring and adhesive application is performed prior to thawing of the dough piece.

Abstract: The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.

Abstract: A system and method for processing medical images using relevancy rules, the relevancy rules used for determining relevant studies for a plurality of clinical software applications. The relevancy rules may apply to the various aspects of study, series, and/or image metadata to determine whether prior images should be processed in an assembled matched set by the clinical application. The relevancy rules may further apply to metadata generated by the clinical software applications in association with the study, series, and/or image data or associated metadata.

Abstract: Provided are methods and compositions for prolonging survival and/or reducing or inhibiting tumor growth in a cancer subject receiving a regimen of one or more chemotherapeutic agents, an inhibitor of soluble epoxide hydrolase (sEHi) and a non-steroidal anti-inflammatory drug (NSAID) that inhibits one or more enzymes selected from the group consisting of cyclo-oxygenase (“COX”)-1, COX-2, and 5-lipoxygenase (“5-LOX”). The methods and compositions decrease toxicity and/or adverse side effects in subjects receiving a regimen of one or more chemotherapeutic agents.

Abstract: A method and downhole tool assembly, of which the method includes measuring a thickness and a location of an outer diameter surface of the tubular at a plurality of transverse planes of the tubular, simulating a cutting process to determine a position for the outer diameter surface of the tubular in a lathe, such that, after the cutting process that was simulated is conducted, the thickness of the tubular is greater than a minimum thickness and an outer diameter defined by the outer diameter surface of the tubular is less than or equal to a maximum diameter, positioning the tubular in the lathe based on the simulation of the cutting process, cutting the outer diameter surface of the tubular to reduce the outer diameter thereof to at most the maximum diameter and thereby form a turned-down region, and positioning the downhole tool on the tubular in the turned-down region.

Abstract: The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a poly(ethylene glycol) polymer, each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided.

Abstract: A plurality of dough pieces are produced using a rotary dough cutter including a shaft, a plurality of walls extending radially outward from the shaft and a plurality of interior blades extending radially outward from the shaft. The plurality of walls define a plurality of dough cutter molds. The plurality of dough cutter molds include a first dough cutter mold and a second dough cutter mold. A first wall of the plurality of walls defines part of both the first dough cutter mold and the second dough cutter mold. Each of the plurality of interior blades is located in one of the plurality of dough cutter molds. The plurality of dough pieces are cut from a dough sheet with the plurality of walls. The plurality of dough pieces are scored with the plurality of interior blades. After scoring, the plurality of dough pieces are proofed and then frozen.

Abstract: Frozen un-proofed dough pieces are produced by pinching an upper skin of an un-proofed dough body to a lower skin and producing a score through the upper skin prior to freezing. The un-proofed dough pieces are formed by mass production, with an un-proofed dough sheet being cut to form dough strips which are then cut into the un-proofed dough pieces, with the score for each un-proofed dough piece being formed either before, during or after the individual un-proofed dough pieces are actually created, but before freezing.

Abstract: The present invention provides a nanodisc with a membrane scaffold protein. The nanodisc includes a membrane scaffold protein, a telodendrimer and a lipid. The membrane scaffold protein can be apolipoprotein. The telodendrimer has the general formula PEG-L-D-(R)n, wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a polyethylene glycol) polymer; each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Cell free methods of making the nanodiscs are also provided.

Abstract: A system and method for processing medical images using relevancy rules, the relevancy rules used for determining relevant studies for a plurality of clinical software applications. The relevancy rules may apply to the various aspects of study, series, and/or image metadata to determine whether prior images should be processed in an assembled matched set by the clinical application. The relevancy rules may further apply to metadata generated by the clinical software applications in association with the study, series, and/or image data or associated metadata.

Abstract: A system and method for processing a plurality of medical images using a plurality of clinical applications. A current study is received by a first server, the current study having first image series metadata. The first server can determine, based on several different techniques, that the current study is in progress. The system and method generates an assembled study set comprising the current study that is processed using a clinical application, the current study having a first series and a second series.

Abstract: A plurality of dough pieces are produced using a rotary dough cutter including a shaft, a plurality of walls extending radially outward from the shaft and a plurality of interior blades extending radially outward from the shaft. The plurality of walls define a plurality of dough cutter molds. The plurality of dough cutter molds include a first dough cutter mold and a second dough cutter mold. A first wall of the plurality of walls defines part of both the first dough cutter mold and the second dough cutter mold. Each of the plurality of interior blades is located in one of the plurality of dough cutter molds. The plurality of dough pieces are cut from a dough sheet with the plurality of walls. The plurality of dough pieces are scored with the plurality of interior blades. After scoring, the plurality of dough pieces are proofed and then frozen.

Abstract: A solar roof tile with an integrated cable management system includes a roof tile weighing less than 400 lbs per 100 square feet of installed roof area and a photovoltaic solar panel attached to a front side of the roof tile. A rear side of the roof tile includes one or more channels configured to accommodate one or more electrical power cables. A method of routing and securing electrical power cables for a solar roof installation using the solar roof tiles is also disclosed.

Abstract: A solar roof tile with an integrated cable management system includes a roof tile weighing less than 400 lbs per 100 square feet of installed roof area and a photovoltaic solar panel attached to a front side of the roof tile. A rear side of the roof tile includes one or more channels configured to accommodate one or more electrical power cables. A method of routing and securing electrical power cables for a solar roof installation using the solar roof tiles is also disclosed.