Abstract: Devices, systems, and methods for occluding cavities or passageways in a subject, such as the left atrial appendage of a subject's heart. The devices, systems, and methods can be used to decrease the rate of thromboembolic events associated with atrial fibrillation by occluding the left atrial appendage.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: Devices, systems, and methods for occluding cavities or passageways in a subject, such as the left atrial appendage of a subject's heart. The devices, systems, and methods can be used to decrease the rate of thromboembolic events associated with atrial fibrillation by occluding the left atrial appendage.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: Devices, systems, and methods for occluding cavities or passageways in a subject, such as the left atrial appendage of a subject's heart. The devices, systems, and methods can be used to decrease the rate of thromboembolic events associated with atrial fibrillation by occluding the left atrial appendage.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: According to one aspect, an apparatus is adapted to be operably coupled to a subsea blowout preventer and includes a first tubular member defining an internal passage, and a second tubular member extending within the internal passage. A sealing assembly is disposed radially between the first and second tubular members, and includes a sealing element. The second tubular member covers the sealing element and thus facilitates protecting the sealing element from any fluid flow through the internal passage. According to another aspect, a sealing element of a connector is protected before engaging the connector with a subsea casing. The connector is engaged with the casing while the sealing element is protected so that the sealing element is fluidically isolated from any fluid flow through the connector. The sealing element sealingly engages the casing.

Abstract: A medicament dispenser comprising: (i) a housing having an outlet; (ii) a medicament container locatable within said housing; (iii) an electronic dose counter associated with said outlet, wherein said dose counter comprises a first sensor for directly detecting a medicament release dispensible from said medicament container through said outlet is disclosed.

Abstract: A medicament dispenser comprising: (i) a housing having an outlet; (ii) a medicament container locatable within said housing; (iii) an electronic dose counter associated with said outlet, wherein said dose counter comprises a first sensor for directly detecting a medicament release dispensible from said medicament container through said outlet is disclosed.

Abstract: An apparatus for diverting a stream of articles, the apparatus including a first conveyor belt conveying a stream of articles along a conveying surface, a second conveyor belt disposed parallel to the first conveyor belt and having a conveying surface, and a carrier arranged to travel along a path parallel to the first and second conveyor belts. A first drive mechanism drives the first conveyor belt at a first speed in a first direction, and a second drive mechanism drives the second conveyor belt at a second speed in a second direction opposite to the first direction. A diverter element is affixed to the carrier and extends across at least a portion of the conveying surfaces of the first and second conveyor belts to divert articles in the stream on the first conveyor belt onto the second conveyor belt. A differential drive mechanism drives the carrier at a speed and in a direction that depend on the first speed and the second speed.

Abstract: In a gene expression profile retrieving apparatus, while gene expression profile data acquired with different platforms can be used, a cell can be retrieved based upon a gene expression profile.

Abstract: Apparatus is disclosed for diverting a stream of articles, the apparatus including a framework, a first conveyor supported in the framework and conveying stream of articles along a first conveying surface, and a second conveyor supported in the framework parallel to the first conveyor and having a second conveying surface. A first drive mechanism drives the first conveyor at a first speed in a first direction, and a second drive mechanism drives the second conveyor at a second speed in a second direction opposite to the first direction. A carrier is arranged to travel along a path parallel to the first and second conveyors, and a diverter element is affixed to the carrier and extending across at least a portion of the conveying surfaces of the first and second conveyors to divert articles in the stream on the first conveyor to the second conveyor.

Abstract: There is provided a medicament dispenser comprising a medicament container having a dispensing mechanism; a container seat for receipt of the container; an anchor station; and drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism. The drive means is actuable in response to the application of non-mechanical energy thereto, and gear means are provided to the drive means to gear up the torque provided thereby.

Abstract: In order to prevent potential electrical hazards associated with supplying power downhole, a hanger is provided for either casing or tubing strings, or a plurality of casing or tubing strings, that electrically insulates the internal suspension mechanism of the hanger from the hanger's external seal. Electrical power is typically transferred through a hanger by way of the internal suspension mechanism. If electrical umbilicals are used, connecting devices may be located within the internal suspension mechanism for connecting an upper and lower umbilical and transferring power trough the hanger. If a rigid tubular conductor is used, the suspension mechanism may be ported to allow the passage of electrical feedthroughs or, in the case of tubing hangers, the tubing itself may be charged with electrical power. By insulating the suspension mechanism from the external seal potential electrical hazards are eliminated.

Abstract: The present invention provides a hanger for either casing or tubing strings that electrically insulates the internal suspension system of the hanger from the hanger's external seal. Electrical power is typically transferred through a hanger via the internal suspension system. If electrical umbilicals are used, connecting devices may be located within the internal suspension system for connecting an upper and lower umbilical and transferring power through the hanger. If a rigid tubular conductor is used, the suspension system may be ported to allow the passage of electrical feedthroughs or, in the case of tubing hangers, the tubing itself maybe charged with electrical power. By insulating the suspension system from the external seal, potential electrical hazards are eliminated.