Abstract: There are provided herein, inter alia, complexes, compositions and methods for a vaccine for COVID-19. The cell-penetrating complexes provided herein may include a nucleic acid non-covalently bound to a cationic amphipathic polymer, the cationic amphipathic polymer including a pH-sensitive immolation domain. The cell-penetrating complexes provided herein are, inter alia, useful in vaccines, wherein the vaccine includes a ribonucleic acid including a sequence encoding a viral protein, a nucleic acid adjuvant and a cationic amphipathic polymer provided herein including embodiments thereof.

Abstract: This invention relates to a binary signaling scheme for use in a transmitter comprising a semiconductor radiation source where the driving current and thus also the radiation output level is modulated by switching the driving current on and off. However, the modulation of the driving current is adapted to not wait for the radiation response to follow the complete rise or fall curve but to switch between two (or a larger number of) selected radiation output levels. During prolonged sequences of zeros (or ones), the driving current is switched to keep the radiation output level between a certain minimum and maximum level. This range of radiation output levels is adaptively selected in accordance with characteristics of the driving current, the optical transmission channel, the radiation source and/or the radiation detector.

Abstract: Radar localization systems and methods are provided to determine the location of an object. The radar localization systems and methods can determine the location of an object based on data obtained from at least two radar measurements made by the radar localization device. In some embodiments, a radar localization system can be included in a wireless communications system that conducts both wireless communications and radar sensing. Radar localization systems include at least a computing unit that performs a radar localization method. Radar localization methods may use map data in object localization to eliminate non-feasible locations of the object.

Abstract: The present invention provides a process for preparing a vegetarian burger comprising the step of mixing hydrated TVP pieces with methyl cellulose, plant protein concentrate, fat, water and defibrillated hydrated texturized fibrous vegetable protein material to produce a vegetarian dough.

Abstract: The invention relates to a minced meat analogue comprising hydrated TVP chunks and hydrated TVP microfibers.

Abstract: According to one aspect disclosed herein, there is provided a client device for use in an optical wireless communications network, the client device comprising a transceiver configured to receive data via an optical wireless connection. The transceiver comprises an upward facing optical transducer configured to detect or transmit an optical wireless transmission, the sensor arranged to have a coverage area with at least two 5 concentric segments. A portion of the sensor is configured to provide an outermost segment of the at least two concentric segments.

Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A method of electrospinning (40) is provided, and an electrospinning device (1; 30). The method comprises (i) holding (41) a liquid comprising a polymer melt or a polymer solution in a container (2), (ii) letting out (42) a stream of the liquid from the container through at least one nozzle (3), (iii) creating (43) a voltage difference between the nozzle (3) and a collecting surface (4), (iv) collecting (44) electro spun material coming from the nozzle (3) so as to form a fibrous structure (8) on the collecting surface (4), and (v) directing (45) a laser beam (13) towards the collecting surface (4) so as to locally remove a part of the fibrous structure (8).

Abstract: A nozzle for an electrospinning spinneret, the nozzle including a material transporting channel having a wall that has an end surface for forming a droplet, and an electrode extending through the material transporting channel at least up to the end surface of the wall.

Abstract: The invention relates to a filtering device for filtering fibrous material from water flowing through a channel, the device comprising a sieve, the sieve being arranged at an angle with respect a flow direction defined by the channel. According to the invention, said angle is smaller than 25°. The invention also relates to a method of installing such a filtering device, a system comprising such a filtering device, and the use of such a device.

Abstract: An improved electro hydrodynamic method is provided. The method comprises arranging (11) an electro hydrodynamic device inside an enclosure and distributing (12) positive and/or negative ions inside the enclosure during a charging period with a certain defined amount of power. The distribution of the positive and/or the negative ions inside the enclosure (20) is performed so that a predefined amount of charge is set on the interior of the enclosure (20). Within a predetermined period of time after the charging period has ended, the electrospinning device is activated so as to create a product. Finally, the product is removed from the device. The present invention offers a solution for the problem of non-identical initial process conditions for an electro hydrodynamic process caused by any electric charges on the equipment.

Abstract: An electrospinning device (1; 30) is provided comprising: a container (2) for holding a liquid comprising a polymer melt or a polymer solution; a nozzle (3) arranged to outlet a stream of the liquid from the container; a collecting surface (4) for collecting electro spun material coming from the nozzle during an electrospinning process so as to form a fibrous structure (8) on the collecting surface (4); a voltage supply system (5) arranged to create a voltage difference between the nozzle and the collecting surface (4), one or more electrostatic emitters (10; 38) arranged to locally distribute positive and/or negative ions onto the fibrous structure, and one or more rotatable bodies (6; 36) arranged to cause the collecting surface (4) to face the nozzle (3) and the electrostatic emitters (10; 38) in turn.

Abstract: Method and device for depositing a fiber material layer on a carrier, such as using an electrospinning process. The device includes a deposition unit positioned remote from the carrier during operation, and the deposition unit is arranged for forming the fiber material layer on the carrier in a continuous manner A carrier feed unit is provided for feeding the carrier in a transport direction with a predetermined speed, and the carrier includes a plurality of carrier plates. A cutting unit is present and arranged downstream from the deposition unit, the cutting unit being arranged to cut the deposited fiber material layer in between two adjacent ones of the plurality of carrier plates.

Abstract: An electrospinning device is provided with a container for holding a liquid comprising a polymer melt or a polymer solution, and a nozzle arranged to outlet a stream of the liquid from the container. A collector collects electro spun material during electrospinning so as to form a fibrous structure. The device comprises an optical measurement system that measures a baseline distance between the collector and the optical measurement system for at least one location on a surface of the collector, and also measures a momentary distance between the optical measurement system and a momentary top layer of the fibrous structure during the electrospinning process. A processor calculates a momentary thickness of the fibrous structure. Once a required thickness is reached the electrospinning can be stopped.

Abstract: An electrospinning device (1; 30) is provided comprising: a container (2) for holding a liquid comprising a polymer melt or a polymer solution; a nozzle (3) arranged to outlet a stream of the liquid from the container; a collecting surface (4) for collecting electro spun material coming from the nozzle during an electrospinning process so as to form a fibrous structure (8) on the collecting surface (4); a voltage supply system (5) arranged to create a voltage difference between the nozzle and the collecting surface (4), one or more electrostatic emitters (10; 38) arranged to locally distribute positive and/or negative ions onto the fibrous structure, and one or more rotatable bodies (6; 36) arranged to cause the collecting surface (4) to face the nozzle (3) and the electrostatic emitters (10; 38) in turn.

Abstract: An improved electro hydrodynamic method is provided. The method comprises arranging (11) an electro hydrodynamic device inside an enclosure and distributing (12) positive and/or negative ions inside the enclosure during a charging period with a certain defined amount of power. The distribution of the positive and/or the negative ions inside the enclosure (20) is performed so that a predefined amount of charge is set on the interior of the enclosure (20). Within a predetermined period of time after the charging period has ended, the electrospinning device is activated so as to create a product. Finally, the product is removed from the device. The present invention offers a solution for the problem of non-identical initial process conditions for an electro hydrodynamic process caused by any electric charges on the equipment.

Abstract: A method of electrospinning (40) is provided, and an electrospinning device (1; 30). The method comprises (i) holding (41) a liquid comprising a polymer melt or a polymer solution in a container (2), (ii) letting out (42) a stream of the liquid from the container through at least one nozzle (3), (iii) creating (43) a voltage difference between the nozzle (3) and a collecting surface (4), (iv) collecting (44) electro spun material coming from the nozzle (3) so as to form a fibrous structure (8) on the collecting surface (4), and (v) directing (45) a laser beam (13) towards the collecting surface (4) so as to locally remove a part of the fibrous structure (8).

Abstract: An electrospinning device is provided with a container for holding a liquid comprising a polymer melt or a polymer solution, and a nozzle arranged to outlet a stream of the liquid from the container. A collector collects electro spun material during electrospinning so as to form a fibrous structure. The device comprises an optical measurement system that measures a baseline distance between the collector and the optical measurement system for at least one location on a surface of the collector, and also measures a momentary distance between the optical measurement system and a momentary top layer of the fibrous structure during the electrospinning process. A processor calculates a momentary thickness of the fibrous structure. Once a required thickness is reached the electrospinning can be stopped.

Abstract: The invention pertains to the use of a composition in the manufacture of a productor method for therapeutically improving, promoting, restoring or maintaining white matter integrity in a subject suffering from PKU and/or in a subject suffering from or at increased risk of impaired white matter integrity associated with PKU, said composition comprising therapeutic amounts of at least one ?-3 polyunsaturated fatty acid (LCPUFA) selected from the group consisting of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA); and one of more of uridine, cytidine and/or an equivalent thereof, including salts, phosphates, acyl derivatives and/or esters. The invention also pertains to a composition for use in such use or method.

Abstract: A probe assembly can be connected and disconnected from its electrical harness within a vacuum chamber so that the probe assembly with the work piece mounted can be rotated and tilted without interference from a cable, and can then be reconnected without opening the vacuum chamber. Also described is a means of grounding a sample and probes when the probe assembly is disconnected from its electrical harness and a means of preventing damage to the probe mechanism and the probe itself by ensuring that the probes are not sticking up too far during operations.