Patents by Inventor Paul Klein

Paul Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12635988
    Abstract: Systems and methods augmenting ultrasound simulations using photon counting computed tomography (CT) data in order to create simulated ultrasound data with fine tissue detail. A virtual volume is generated from acoustic properties derived from the photon counting CT data. Simulated ultrasound data is generated by placing a simulated transducer at various positions in the virtual volume.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: May 26, 2026
    Assignee: Siemens Healthineers AG
    Inventors: Abdoul Aziz Amadou, Paul Klein
  • Publication number: 20260076646
    Abstract: Systems and methods for left atrial appendage closure device specification from two dimensional (2D) Intracardiac Echo imaging (ICE). In an imaging procedure, 2D ICE is used to acquire images of the left atrium of a patient. A model of the left atrium is generated from the images of the left atrium. The model of the left atrium is used to validate subsequent imaging of the left atrial appendage of the patient. Anatomical measurements from the validated subsequent imaging may be used to select or specify a left atrial appendage closure device in order to, for example, treat atrial fibrillation patients.
    Type: Application
    Filed: September 19, 2024
    Publication date: March 19, 2026
    Inventors: Gareth Funka-Lea, Athira Jane Jacob, Paul Klein
  • Patent number: 12567150
    Abstract: Systems and methods for generating an updated segmentation of an initial segmentation are provided. An initial segmentation of an anatomical object from an input medical image is received. User input modifying the initial segmentation is received. An updated segmentation of the anatomical object in the input medical image is generated using a machine learning based network based on at least one of the initial segmentation and the user input. The updated segmentation is output.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: March 3, 2026
    Assignee: Siemens Healthineers AG
    Inventors: Noha El-Zehiry, Gareth Funka-Lea, Athira Jane Jacob, Paul Klein
  • Publication number: 20250278895
    Abstract: Systems and methods for three dimensional reconstruction from two dimensional imaging data. An neural implicit shape function model is used to regress a shape of an organ from two dimensional sparse imaging data. Contours of the organ are generated from the two dimensional sparse imaging data. The contours are used to train the neural implicit shape function model to regress the shape of the organ.
    Type: Application
    Filed: June 20, 2024
    Publication date: September 4, 2025
    Inventors: Athira Jane Jacob, Paul Klein, Gareth Funka-Lea
  • Publication number: 20250000492
    Abstract: Systems and methods augmenting ultrasound simulations using photon counting computed tomography (CT) data in order to create simulated ultrasound data with fine tissue detail. A virtual volume is generated from acoustic properties derived from the photon counting CT data. Simulated ultrasound data is generated by placing a simulated transducer at various positions in the virtual volume.
    Type: Application
    Filed: June 30, 2023
    Publication date: January 2, 2025
    Inventors: Abdoul Aziz Amadou, Paul Klein
  • Patent number: 12175668
    Abstract: Systems and methods for determining a semantic image understanding of medical imaging studies are provided. A plurality of medical imaging studies associated with a plurality of medical imaging modalities is provided. Metadata associated with each of the plurality of medical imaging studies is generated by performing a plurality of semantic image analysis tasks using one or more machine learning based networks. The metadata associated with each of the plurality of medical imaging studies is output.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: December 24, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Ingo Schmuecking, Puneet Sharma, Desiree Komuves, Tiziano Passerini, Paul Klein
  • Publication number: 20240331860
    Abstract: A medical knowledge base in a digital, clinical system is upgraded. A storage with a knowledge base, being a SNOMED knowledge base, is provided in a web ontology format. Procedural data, representing clinical procedures for evaluation of a patient's health state, is received. The received procedural data is mapped in a set of SNOMED expressions. The SNOMED expressions are converted into statements in the web ontology format. The SNOMED knowledge base is upgraded with the received procedural data by adding the statements in the SNOMED knowledge base for providing a processable file with an upgraded version of the SNOMED knowledge base.
    Type: Application
    Filed: March 16, 2022
    Publication date: October 3, 2024
    Inventors: Poikavila Ullaskrishnan, Tiziano Passerini, Puneet Sharma, Paul Klein, Teodora-Vanessa Liliac, Larisa Micu
  • Publication number: 20240246371
    Abstract: The present disclosure relates to a magnetic tire protection system incorporating one or a plurality of magnets arranged internally within a tire such that the magnetic field produced by each respective magnet repels magnetic objects within the road or operating environment away from the tire. The magnetic tire protection system may incorporate electromagnets with corresponding power sources to selectively produce the magnetic field produced by each respective electromagnet when it near a surface on which a tire is operating.
    Type: Application
    Filed: January 19, 2023
    Publication date: July 25, 2024
    Inventor: Paul Klein
  • Patent number: 12004860
    Abstract: A method includes processing at least one input dataset (using a multi-level processing algorithm, one or more of the at least one input dataset comprising imaging data of an echocardiography of a cardiovascular system of a patient. The multi-level processing algorithm comprises a multi-task level and a consolidation-task level. An input of the consolidation-task level is coupled to an output of the multi-task level. The multi-task level is configured to determine multiple diagnostic metrics of the cardiovascular system based on the at least one input dataset. The consolidation-task level is configured to determine a fitness of the cardiovascular system of the patient.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: June 11, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Paul Klein, Ingo Schmuecking, Costin Florian Ciusdel, Lucian Mihai Itu, Tiziano Passerini, Puneet Sharma
  • Publication number: 20230334655
    Abstract: Systems and methods for determining a semantic image understanding of medical imaging studies are provided. A plurality of medical imaging studies associated with a plurality of medical imaging modalities is provided. Metadata associated with each of the plurality of medical imaging studies is generated by performing a plurality of semantic image analysis tasks using one or more machine learning based networks. The metadata associated with each of the plurality of medical imaging studies is output.
    Type: Application
    Filed: April 14, 2022
    Publication date: October 19, 2023
    Inventors: Ingo Schmuecking, Puneet Sharma, Desiree Komuves, Tiziano Passerini, Paul Klein
  • Patent number: 11589924
    Abstract: A method and system for non-invasive assessment and therapy planning for coronary artery disease from medical image data of a patient is disclosed. Geometric features representing at least a portion of a coronary artery tree of the patient are extracted from medical image data. Lesions are detected in coronary artery tree of the patient and a hemodynamic quantity of interest is computed at a plurality of points along the coronary artery tree including multiple points within the lesions based on the extracted geometric features using a machine learning model, resulting in an estimated pullback curve for the hemodynamic quantity of interest.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: February 28, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Tiziano Passerini, Thomas Redel, Paul Klein, Lucian Mihai Itu, Saikiran Rapaka, Puneet Sharma
  • Publication number: 20230060113
    Abstract: Systems and methods for generating an updated segmentation of an initial segmentation are provided. An initial segmentation of an anatomical object from an input medical image is received. User input modifying the initial segmentation is received. An updated segmentation of the anatomical object in the input medical image is generated using a machine learning based network based on at least one of the initial segmentation and the user input. The updated segmentation is output.
    Type: Application
    Filed: July 8, 2022
    Publication date: February 23, 2023
    Inventors: Noha El-Zehiry, Gareth Funka-Lea, Athira Jane Jacob, Paul Klein
  • Publication number: 20220310260
    Abstract: A medical knowledge base in a digital, clinical system is upgraded. A storage with a knowledge base, being a SNOMED knowledge base, is provided in a web ontology format. Procedural data, representing clinical procedures for evaluation of a patient's health state, is received. The received procedural data is mapped in a set of SNOMED expressions. The SNOMED expressions are converted into statements in the web ontology format. The SNOMED knowledge base is upgraded with the received procedural data by adding the statements in the SNOMED knowledge base for providing a processable file with an upgraded version of the SNOMED knowledge base.
    Type: Application
    Filed: March 16, 2022
    Publication date: September 29, 2022
    Inventors: Poikavila Ullaskrishnan, Tiziano Passerini, Puneet Sharma, Paul Klein, Teodora-Vanessa Liliac, Larisa Micu
  • Publication number: 20220031218
    Abstract: A method includes processing at least one input dataset (using a multi-level processing algorithm, one or more of the at least one input dataset comprising imaging data of an echocardiography of a cardiovascular system of a patient. The multi-level processing algorithm comprises a multi-task level and a consolidation-task level. An input of the consolidation-task level is coupled to an output of the multi-task level. The multi-task level is configured to determine multiple diagnostic metrics of the cardiovascular system based on the at least one input dataset. The consolidation-task level is configured to determine a fitness of the cardiovascular system of the patient.
    Type: Application
    Filed: July 7, 2021
    Publication date: February 3, 2022
    Inventors: Paul Klein, Ingo Schmuecking, Costin Florian Ciusdel, Lucian Mihai Itu, Tiziano Passerini, Puneet Sharma
  • Publication number: 20210085397
    Abstract: A method and system for non-invasive assessment and therapy planning for coronary artery disease from medical image data of a patient is disclosed. Geometric features representing at least a portion of a coronary artery tree of the patient are extracted from medical image data. Lesions are detected in coronary artery tree of the patient and a hemodynamic quantity of interest is computed at a plurality of points along the coronary artery tree including multiple points within the lesions based on the extracted geometric features using a machine learning model, resulting in an estimated pullback curve for the hemodynamic quantity of interest.
    Type: Application
    Filed: July 26, 2018
    Publication date: March 25, 2021
    Inventors: Tiziano Passerini, Thomas Redel, Paul Klein, Lucian Mihai Itu, Saikiran Rapaka, Puneet Sharma
  • Publication number: 20150246388
    Abstract: Described herein, in a preferred embodiment, is a leonardite-based polyurethane resin binder that may be used, among other applications, as a binder in combination with foundry aggregate, e.g., sand, for molding or casting metal parts. The binders described herein comprise a humic substance, preferably leonardite, first mixed with a foundry aggregate and then the humic-aggregate mixture is combined with a polymerizable polyol, an isocyanate, and a polymerization catalyst to make a polyurethane resin binder in situ in a foundry aggregate, such as sand. The lignite is added as a solid to the foundry aggregate, and improves the binder performance of the lignite-containing part of the binder components.
    Type: Application
    Filed: May 15, 2015
    Publication date: September 3, 2015
    Inventors: Joseph M. Fuqua, Paul Klein
  • Patent number: 8426494
    Abstract: Described herein, in a preferred embodiment, is a leonardite-based polyurethane resin binder that may be used, among other applications, as a binder in combination with foundry aggregate, e.g., sand, for molding or casting metal parts. The binders described herein comprise a humic substance, preferably leonardite, first mixed with a foundry aggregate and then the humic-aggregate mixture is combined with a polymerizable polyol, an isocyanate, and a polymerization catalyst to make a polyurethane resin binder in situ in a foundry aggregate, such as sand. The lignite is added as a solid to the foundry aggregate, and improves the binder performance of the lignite-containing part of the binder components.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: April 23, 2013
    Assignee: Amcol International Corp.
    Inventors: Joseph M. Fuqua, Paul Klein
  • Publication number: 20110079366
    Abstract: Described herein, in a preferred embodiment, is a leonardite-based polyurethane resin binder that may be used, among other applications, as a binder in combination with foundry aggregate, e.g., sand, for molding or casting metal parts. The binders described herein comprise a humic substance, preferably leonardite, first mixed with a foundry aggregate and then the humic-aggregate mixture is combined with a polymerizable polyol, an isocyanate, and a polymerization catalyst to make a polyurethane resin binder in situ in a foundry aggregate, such as sand. The lignite is added as a solid to the foundry aggregate, and improves the binder performance of the lignite-containing part of the binder components.
    Type: Application
    Filed: October 6, 2009
    Publication date: April 7, 2011
    Inventors: Joseph M. Fuqua, Paul Klein
  • Publication number: 20070168996
    Abstract: Various embodiments of a computer-implemented method, system and computer program product monitor the performance of a program component executing in a virtual machine. Breakpoints associated with position indicators within the program component are set. In response to reaching one of the breakpoints, an amount of time consumed between the breakpoint and a previous breakpoint is determined. The amount of time associated with the position indicators is accumulated. The amount of time is associated with a position indicator that is associated with the previous breakpoint.
    Type: Application
    Filed: December 16, 2005
    Publication date: July 19, 2007
    Inventor: Paul Klein
  • Publication number: 20070168976
    Abstract: Various embodiments of a computer-implemented method, system and computer program product determine degradation of an application program. At least one execution state of the application program, executing in a virtual machine, is sampled. A number of occurrences of the at least one execution state are counted to provide at least one count. The at least one execution state and at least one count, respectively, are stored.
    Type: Application
    Filed: December 16, 2005
    Publication date: July 19, 2007
    Inventor: Paul Klein