Patents by Inventor Paul Krenitsky

Paul Krenitsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLES USEFUL AS MODULATORS OF ION CHANNELS
    Publication number: 20110059984
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 8, 2010
    Publication date: March 10, 2011
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Dean Wilson, Andreas Termin, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Heterocycles useful as modulators of ion channels
    Patent number: 7880008
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: February 1, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Andreas Termin, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Pyrimidines and pyrazines useful as modulators of ion channels
    Patent number: 7858786
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: December 28, 2010
    Assignee: Vertex Pharmaceuticals Incoropated
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi, Urvi Sheth
  • QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS
    Publication number: 20100249100
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 29, 2010
    Publication date: September 30, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Dean Wilson, Lev Fanning, Paul Krenitsky, Joshua Boger
  • Quinazolines useful as modulators of ion channels
    Patent number: 7718658
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: May 18, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Lev Fanning, Paul Krenitsky, Joshua Boger
  • Biaryls useful as modulators of ion channels
    Patent number: 7705002
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: April 27, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Dean Wilson, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Pyridines useful as modulators of ion channels
    Patent number: 7683065
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi
  • Quinazolines useful as modulators of ion channels
    Publication number: 20090312342
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 3, 2006
    Publication date: December 17, 2009
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Lev Fanning, Timothy Neubert, Paul Krenitsky, Pramod Joshi, Dennis Hurley, Urvi Sheth
  • AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090118333
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 7, 2009
    Inventors: Weichuan Caroline Chen, Paul Krenitsky, Andreas Termin, Dean Wilson
  • ARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090118338
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 7, 2009
    Inventors: Weichuan Caroline Chen, Paul Krenitsky, Pramod Joshi, Andreas Termin, Dean Wilson
  • HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090099233
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: April 16, 2009
    Inventors: Pramod Joshi, Paul Krenitsky, Andreas Termin, Dean Wilson
  • Heterocycles useful as modulators of ion channels
    Publication number: 20080255147
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 26, 2006
    Publication date: October 16, 2008
    Inventors: Dean Wilson, Andreas Termin, Lev T.D. Fanning, Paul Krenitsky, Pramod Joshi
  • Quinazolines useful as modulators of voltage gated ion channels
    Publication number: 20080221137
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 13, 2006
    Publication date: September 11, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • QUINAZOLINES USEFUL AS MODULATORS OF VOLTAGE GATED ION CHANNELS
    Publication number: 20080167305
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 18, 2008
    Publication date: July 10, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • Biaryls useful as modulators of ion channels
    Publication number: 20080090837
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 15, 2006
    Publication date: April 17, 2008
    Inventors: Andreas Termin, Dean Wilson, Lev Fanning, Paul Krenitsky, Pramod Joshi
  • Thienopyrimidines useful as modulators of ion channels
    Publication number: 20070287717
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: June 12, 2007
    Publication date: December 13, 2007
    Inventors: Lev Fanning, Pramod Joshi, Paul Krenitsky, Andreas Termin, Dean Wilson, Yulian Zhang
  • Compositions useful as inhibitors of voltage-gated sodium channels
    Publication number: 20070238733
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: April 11, 2007
    Publication date: October 11, 2007
    Inventors: Pramod Joshi, Paul Krenitsky, Jesus Gonzalez, Jian Wang, Dean Wilson, Andreas Termin
  • Pyrimidines and pyrazines useful as modulators of ion channels
    Publication number: 20070093454
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 4, 2006
    Publication date: April 26, 2007
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi, Urvi Sheth
  • Pyridines useful as modulators of ion channels
    Publication number: 20070082889
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 4, 2006
    Publication date: April 12, 2007
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi
  • Quinazolines useful as modulators of ion channels
    Publication number: 20060173018
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: August 31, 2005
    Publication date: August 3, 2006
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Lev Fanning, Timothy Neubert, Paul Krenitsky, Pramod Joshi, Dennis Hurley, Urvi Sheth