Patents by Inventor Paul Little
Paul Little has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12116452Abstract: A blend composition comprising a first polyester and a second polyester. The first and second polyesters each comprises residues of terephthalic acid, neopentyl glycol (NPG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and/or diethylene glycol (DEG). The first polyester comprises NPG, CHDM, and DEG in a combined amount that is less than the second polyester. The blend composition can be useful for producing a shrink film exhibiting high ultimate shrinkage (e.g., >65% at 95° C. for 10 seconds) and a high strain induced crystalline melting point (e.g., greater than 190° C.).Type: GrantFiled: October 8, 2019Date of Patent: October 15, 2024Assignee: Eastman Chemical CompanyInventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, Jr., James Carl Williams, James Wesley Peer
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Patent number: 12000778Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.Type: GrantFiled: May 17, 2021Date of Patent: June 4, 2024Assignee: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
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Publication number: 20230374143Abstract: The present invention relates to the use of sortilin antagonists, in particular compounds of Formula (I), (II), (III), and (IV), in the treatment or prevention of hearing loss. Also provided are pharmaceutical compositions comprising the sortilin antagonists herein disclosed and methods for the treatment or prevention of hearing loss in a subject in need thereof.Type: ApplicationFiled: October 7, 2021Publication date: November 23, 2023Inventors: Mads Fuglsang KJØLBY, Anders NYKJÆR, Paul LITTLE, Manuel CASES
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Patent number: 11714037Abstract: An NIR analyzer with the optical probes across a pipe, or in a bypass configuration, after a stabilizer in an oil or condensate production plant. Prior to use, liquid samples from the plant are analyzed in a chemical lab to obtain reference vapor pressure or compositional values. A chemometric model using known techniques is then built with the captured absorption spectra and the reference lab results. Preprocessing methodologies can be used to help mitigate interferences of the fluid, instrument drift, and contaminate build up on the lenses in contact with the fluid. The chemometric model is implemented through the NIR analyzer as the calibration curve to predict the vapor pressure or other values of the flowing fluid in real time.Type: GrantFiled: August 21, 2019Date of Patent: August 1, 2023Assignee: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Jie Zhu
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Publication number: 20230144901Abstract: The present invention relates to the use of sortilin antagonists, in particular compounds of Formula (I) and preferably Formula (II), in the treatment or prevention of diabetic retinopathy. Also provided are pharmaceutical compositions comprising the sortilin antagonists herein disclosed and methods for the treatment or prevention of diabetic retinopathy in a subject in need thereof.Type: ApplicationFiled: March 19, 2021Publication date: May 11, 2023Inventors: Mads Fuglsang KJOLBY, Anders NYKJAER, Paul LITTLE, Andreas JURGEIT
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Publication number: 20230128818Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable film(s) or sheet(s) comprising blends of polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), diethylene glycol (DEG) and/or 2,2,4, 4-tetramethyl-1,3-butanediol (TMCD), in certain compositional ranges having certain advantages and improved properties.Type: ApplicationFiled: April 6, 2021Publication date: April 27, 2023Applicant: Eastman Chemical CompanyInventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, JR., James Carl Williams, James Wesley Peer
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Publication number: 20210394468Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable sheets comprising amorphous polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and diethylene glycol (DEG), in certain compositional ranges having certain advantages and improved properties including recyclability.Type: ApplicationFiled: October 8, 2019Publication date: December 23, 2021Applicant: Eastman Chemical CompanyInventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, JR., James Carl Williams
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Publication number: 20210395446Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable film(s) or sheet(s) comprising blends of polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and diethylene glycol (DEG), in certain compositional ranges having certain advantages and improved properties.Type: ApplicationFiled: October 8, 2019Publication date: December 23, 2021Applicant: Eastman Chemical CompanyInventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, Jr., James Carl Williams, James Wesley Peer
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Patent number: 11204316Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.Type: GrantFiled: April 23, 2020Date of Patent: December 21, 2021Assignee: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew R. Thomas
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Patent number: 11150181Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.Type: GrantFiled: December 5, 2018Date of Patent: October 19, 2021Assignee: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
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Publication number: 20210270729Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.Type: ApplicationFiled: May 17, 2021Publication date: September 2, 2021Applicant: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
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Publication number: 20210086468Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 26 mole % neopentyl glycol residues; (ii) about less than 10 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.Type: ApplicationFiled: December 2, 2020Publication date: March 25, 2021Applicant: Eastman Chemical CompanyInventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, JR., James Wesley Peer, Jacob E. Napierala
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Patent number: 10882272Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.Type: GrantFiled: December 11, 2019Date of Patent: January 5, 2021Assignee: Eastman Chemical CompanyInventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, Jr., James Wesley Peer, Jacob E. Napierala
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Publication number: 20200270395Abstract: Disclosed are void-containing films and shrinkable films which show excellent density reduction that is retained upon exposures to high temperatures. The voiding agents are hollow glass microspheres. The shrinkable films have high shrinkage and retain their low density after processing under conditions of temperature and moisture used in typical recycling processes. The films are useful as for sleeves, labels, laminates and other shrinkable film applications, and their lower density allows them to be readily separated from soft drink bottles, food containers and the like during recycling operations.Type: ApplicationFiled: October 30, 2018Publication date: August 27, 2020Applicant: Eastman Chemical CompanyInventors: James Wesley Peer, Sunny A. Bhat, James Carl Williams, Rondell Paul Little, Kevin Michael Cable, Mark Allen Peters
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Publication number: 20200249155Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.Type: ApplicationFiled: April 23, 2020Publication date: August 6, 2020Applicant: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew R. Thomas
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Patent number: 10670519Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.Type: GrantFiled: September 25, 2018Date of Patent: June 2, 2020Assignee: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Matthew R. Thomas
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Publication number: 20200114614Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.Type: ApplicationFiled: December 11, 2019Publication date: April 16, 2020Applicant: Eastman Chemical CompanyInventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, JR., James Wesley Peer, Jacob E. Napierala
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Publication number: 20200049604Abstract: An NIR analyzer with the optical probes across a pipe, or in a bypass configuration, after a stabilizer in an oil or condensate production plant. Prior to use, liquid samples from the plant are analyzed in a chemical lab to obtain reference vapor pressure or compositional values. A chemometric model using known techniques is then built with the captured absorption spectra and the reference lab results. Preprocessing methodologies can be used to help mitigate interferences of the fluid, instrument drift, and contaminate build up on the lenses in contact with the fluid. The chemometric model is implemented through the NIR analyzer as the calibration curve to predict the vapor pressure or other values of the flowing fluid in real time.Type: ApplicationFiled: August 21, 2019Publication date: February 13, 2020Applicant: JP3 Measurement, LLCInventors: Joseph Paul Little, III, Jie Zhu
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Patent number: 10543656Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.Type: GrantFiled: January 11, 2018Date of Patent: January 28, 2020Assignee: Eastman Chemical CompanyInventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, Jr., James Wesley Peer, Jacob E. Napierala
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Patent number: D1014887Type: GrantFiled: March 25, 2022Date of Patent: February 13, 2024Inventor: Paul Little