Patents by Inventor Paul Little

Paul Little has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12116452
    Abstract: A blend composition comprising a first polyester and a second polyester. The first and second polyesters each comprises residues of terephthalic acid, neopentyl glycol (NPG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and/or diethylene glycol (DEG). The first polyester comprises NPG, CHDM, and DEG in a combined amount that is less than the second polyester. The blend composition can be useful for producing a shrink film exhibiting high ultimate shrinkage (e.g., >65% at 95° C. for 10 seconds) and a high strain induced crystalline melting point (e.g., greater than 190° C.).
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: October 15, 2024
    Assignee: Eastman Chemical Company
    Inventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, Jr., James Carl Williams, James Wesley Peer
  • Patent number: 12000778
    Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: June 4, 2024
    Assignee: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
  • Publication number: 20230374143
    Abstract: The present invention relates to the use of sortilin antagonists, in particular compounds of Formula (I), (II), (III), and (IV), in the treatment or prevention of hearing loss. Also provided are pharmaceutical compositions comprising the sortilin antagonists herein disclosed and methods for the treatment or prevention of hearing loss in a subject in need thereof.
    Type: Application
    Filed: October 7, 2021
    Publication date: November 23, 2023
    Inventors: Mads Fuglsang KJØLBY, Anders NYKJÆR, Paul LITTLE, Manuel CASES
  • Patent number: 11714037
    Abstract: An NIR analyzer with the optical probes across a pipe, or in a bypass configuration, after a stabilizer in an oil or condensate production plant. Prior to use, liquid samples from the plant are analyzed in a chemical lab to obtain reference vapor pressure or compositional values. A chemometric model using known techniques is then built with the captured absorption spectra and the reference lab results. Preprocessing methodologies can be used to help mitigate interferences of the fluid, instrument drift, and contaminate build up on the lenses in contact with the fluid. The chemometric model is implemented through the NIR analyzer as the calibration curve to predict the vapor pressure or other values of the flowing fluid in real time.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: August 1, 2023
    Assignee: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Jie Zhu
  • Publication number: 20230144901
    Abstract: The present invention relates to the use of sortilin antagonists, in particular compounds of Formula (I) and preferably Formula (II), in the treatment or prevention of diabetic retinopathy. Also provided are pharmaceutical compositions comprising the sortilin antagonists herein disclosed and methods for the treatment or prevention of diabetic retinopathy in a subject in need thereof.
    Type: Application
    Filed: March 19, 2021
    Publication date: May 11, 2023
    Inventors: Mads Fuglsang KJOLBY, Anders NYKJAER, Paul LITTLE, Andreas JURGEIT
  • Publication number: 20230128818
    Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable film(s) or sheet(s) comprising blends of polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), diethylene glycol (DEG) and/or 2,2,4, 4-tetramethyl-1,3-butanediol (TMCD), in certain compositional ranges having certain advantages and improved properties.
    Type: Application
    Filed: April 6, 2021
    Publication date: April 27, 2023
    Applicant: Eastman Chemical Company
    Inventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, JR., James Carl Williams, James Wesley Peer
  • Publication number: 20210394468
    Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable sheets comprising amorphous polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and diethylene glycol (DEG), in certain compositional ranges having certain advantages and improved properties including recyclability.
    Type: Application
    Filed: October 8, 2019
    Publication date: December 23, 2021
    Applicant: Eastman Chemical Company
    Inventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, JR., James Carl Williams
  • Publication number: 20210395446
    Abstract: The present disclosure relates to crystallizable shrinkable films and thermoformable film(s) or sheet(s) comprising blends of polyester compositions which comprise residues of terephthalic acid, neopentyl glycol (NRG), 1,4-cyclohexanedimethanol (CHDM), ethylene glycol (EG), and diethylene glycol (DEG), in certain compositional ranges having certain advantages and improved properties.
    Type: Application
    Filed: October 8, 2019
    Publication date: December 23, 2021
    Applicant: Eastman Chemical Company
    Inventors: Mark Allen Peters, Jacob E. Napierala, Rondell Paul Little, Jr., James Carl Williams, James Wesley Peer
  • Patent number: 11204316
    Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: December 21, 2021
    Assignee: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew R. Thomas
  • Patent number: 11150181
    Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: October 19, 2021
    Assignee: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
  • Publication number: 20210270729
    Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Applicant: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew Thomas, Gregg Williams, James Stephen Dixson, III
  • Publication number: 20210086468
    Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 26 mole % neopentyl glycol residues; (ii) about less than 10 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.
    Type: Application
    Filed: December 2, 2020
    Publication date: March 25, 2021
    Applicant: Eastman Chemical Company
    Inventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, JR., James Wesley Peer, Jacob E. Napierala
  • Patent number: 10882272
    Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: January 5, 2021
    Assignee: Eastman Chemical Company
    Inventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, Jr., James Wesley Peer, Jacob E. Napierala
  • Publication number: 20200270395
    Abstract: Disclosed are void-containing films and shrinkable films which show excellent density reduction that is retained upon exposures to high temperatures. The voiding agents are hollow glass microspheres. The shrinkable films have high shrinkage and retain their low density after processing under conditions of temperature and moisture used in typical recycling processes. The films are useful as for sleeves, labels, laminates and other shrinkable film applications, and their lower density allows them to be readily separated from soft drink bottles, food containers and the like during recycling operations.
    Type: Application
    Filed: October 30, 2018
    Publication date: August 27, 2020
    Applicant: Eastman Chemical Company
    Inventors: James Wesley Peer, Sunny A. Bhat, James Carl Williams, Rondell Paul Little, Kevin Michael Cable, Mark Allen Peters
  • Publication number: 20200249155
    Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.
    Type: Application
    Filed: April 23, 2020
    Publication date: August 6, 2020
    Applicant: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew R. Thomas
  • Patent number: 10670519
    Abstract: A system of spectroscopic devices deployed amongst the fluid infrastructure of hydrocarbon fluids are described herein. The devices provide early visibility into the characteristics of those fluids which inform and educate downstream parties of the potential value of the fluid, or the opportunity to reblend or redirect the fluid to optimize the formulization. By allowing downstream parties to determine the quality and quantity of refined products at an early stage, they are better able to determine the true value of the fluid. The data from the distributed network of spectroscopic analyzers provides valuation information that can be used to make more informed purchasing decisions or allow processors to create blends that optimize the efficiency of refining operations.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: June 2, 2020
    Assignee: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Matthew R. Thomas
  • Publication number: 20200114614
    Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.
    Type: Application
    Filed: December 11, 2019
    Publication date: April 16, 2020
    Applicant: Eastman Chemical Company
    Inventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, JR., James Wesley Peer, Jacob E. Napierala
  • Publication number: 20200049604
    Abstract: An NIR analyzer with the optical probes across a pipe, or in a bypass configuration, after a stabilizer in an oil or condensate production plant. Prior to use, liquid samples from the plant are analyzed in a chemical lab to obtain reference vapor pressure or compositional values. A chemometric model using known techniques is then built with the captured absorption spectra and the reference lab results. Preprocessing methodologies can be used to help mitigate interferences of the fluid, instrument drift, and contaminate build up on the lenses in contact with the fluid. The chemometric model is implemented through the NIR analyzer as the calibration curve to predict the vapor pressure or other values of the flowing fluid in real time.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 13, 2020
    Applicant: JP3 Measurement, LLC
    Inventors: Joseph Paul Little, III, Jie Zhu
  • Patent number: 10543656
    Abstract: The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: January 28, 2020
    Assignee: Eastman Chemical Company
    Inventors: Mark Allen Peters, James Carl Williams, Rondell Paul Little, Jr., James Wesley Peer, Jacob E. Napierala
  • Patent number: D1014887
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: February 13, 2024
    Inventor: Paul Little