Abstract: A bicycle storage unit is disclosed. The unit includes a rotatable bicycle storage carousel that is structured to rotate about a central axis to provide for a dense storage of bicycles, which are stored on the rotatable bicycle storage carousel in a generally vertical orientation. The unit further includes an enclosure surrounding the carousel. The rotatable bicycle storage carousel comprises an elongated central core oriented in a first direction that is orthogonal relative to a plane defined by a base structure of the rotatable bicycle storage carousel. The elongated central core is rotatable relative to the base structure. The carousel further includes multiple bicycle storage assemblies on which bicycles can be hung.

Abstract: A metered volume microfluidic device can include fluid flow microfluidics. The fluid flow microfluidics can include an inflow channel, a metered volume chamber positioned to receive working fluid from the inflow channel, a metered volume outflow channel positioned to receive and direct a metered volume of the working fluid when discharged from the metered volume chamber, and a capillary check valve. The capillary check valve can allow excess working fluid to exit the metered volume chamber when filling the metered volume chamber via the inflow channel. The capillary check valve can also prevent excess working fluid that has passed there through from being reintroduced into the metered volume chamber when the working fluid is discharged into the metered volume outflow channel.

Abstract: Methods for treating uterine fibroids, endometriosis, adenomyosis, or heavy menstrual bleeding in a subject, which include administering to the subject from 10 mg to 60 mg per day of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N?-methoxyurea, and from 0.01 mg to 5 mg per day of a hormone replacement medicament. The present disclosure has methods for reducing menstrual bleeding in a subject, reducing bone mineral density loss in a subject caused by administering a GnRH antagonist to the subject, suppressing sex hormones in a subject, reducing vasomotor symptoms or hot flashes in a subject, and reducing symptoms of decreased libido in a subject having uterine fibroids, endometriosis, or adenomyosis.

Abstract: A hybrid electric propulsion (HEP) system can include a heat engine torque sensor connected between a heat engine and a combining gear box to sense a heat motor input torque input to the combining gear box, an electric motor torque sensor connected between an electric motor and the combining gear box to sense an electric motor input torque input to the combining gear box, and a combining gear box torque sensor connected to an output of the combining gearbox. The system can include a HEP controller operatively connected to each of the heat engine torque sensor, the electric motor torque sensor, and the combining gear box torque sensor to receive one or more torque signals therefrom. The controller can be configured to output one or more output signals as a function of the signals from each of the heat engine torque sensor, the electric motor torque sensor, and the combining gear box torque sensor.

Abstract: A visualization system comprising a persistent memory, storing a dataset, and a non-persistent memory implements a pattern visualizing method. The dataset contains discrete attribute values for each first entity of a first type in a plurality of first entities of the first type and discrete attribute values for each first entity of a second type in a plurality of first entities of the second type for each second entity in a plurality of second entities. The dataset is compressed by blocked compression and represents discrete attribute values in both compressed sparse row and column formats. The discrete attribute values are clustered to assign each second entity to a cluster in a plurality of clusters.

Abstract: Pharmaceutical compositions and methods of their use are provided for reducing inflammation in a subject, blocking leukocyte recruitment, inhibiting tumor metastasis, treating sepsis and preventing/reducing acute kidney injury.

Abstract: A bicycle storage unit is disclosed. The unit includes a rotatable bicycle storage carousel that is structured to rotate about a central axis to provide for a dense storage of bicycles, which are stored on the rotatable bicycle storage carousel in a generally vertical orientation. The unit further includes an enclosure surrounding the carousel. The rotatable bicycle storage carousel comprises an elongated central core oriented in a first direction that is orthogonal relative to a plane defined by a base structure of the rotatable bicycle storage carousel. The elongated central core is rotatable relative to the base structure. The carousel further includes multiple bicycle storage assemblies on which bicycles can be hung.

Abstract: A sample preparation blister pack can include a plurality of reservoirs formed as blisters. The reservoirs can have an actuatable barrier layer and a seal barrier layer with contents of the reservoirs between the actuatable barrier layer and the seal barrier layer. The contents can be to facilitate isolating a biological component from a biological sample. The individual reservoirs can be adapted to release the contents through the seal barrier layer upon actuation of the actuatable barrier layer. The blister pack can have a width and a length and the reservoirs can be lined up along the length. In this example, a first reservoir contains an inert mechanical fluid and a second reservoir contains a reagent, a buffer, or a combination thereof.

Abstract: An audio filtering and power extraction apparatus for filtering out audio signal and extracting power from a combined signal and direct-current power line, with an input configured to couple to a combined signal and direct-current power line, a filtering extractor system functionally coupled to the input, a DC sensing switch circuit, and a second order low-pass filter functionally coupled to the DC sensing switch circuit, the second order low-pass filter including, an inductor, a capacitor and resistor in series with each other, and an output functionally coupled to an output of the filtering extractor system and through which output extracted power is provided.

Abstract: The technology disclosed herein enables detection of domain hijacking when a DNS resolver is performing a DNS lookup. In a particular embodiment, a method provides, in response to a request to resolve a network address corresponding to a domain name, determining that a nameserver for the domain name is suspect based on satisfaction of nameserver criteria associated with the domain name. The method further includes preventing the nameserver from being used to resolve the request in response to determining that the nameserver is suspect.

Abstract: A label modification unit may receive a label modification input that indicates a label modification associated with content being written to a label or erased from the label. The label modification unit may identify an area of the label that is associated with the label modification according to the label modification input. The label modification unit may determine, based on a size of the area, a spot size of a light beam that is configured to be emitted by a laser printhead to modify the content within the area. The label modification unit may determine, based on the spot size and the content, an optical path configuration for the laser printhead. The label modification unit may operate the laser printhead according to the optical path configuration to write the content to the area or erase the content from the area.

Abstract: Methods for treating uterine fibroids, endometriosis, adenomyosis, or heavy menstrual bleeding in a subject, which include administering to the subject from 10 mg to 60 mg per day of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N?-methoxyurea, and from 0.01 mg to 5 mg per day of a hormone replacement medicament. The present disclosure has methods for reducing menstrual bleeding in a subject, reducing bone mineral density loss in a subject caused by administering a GnRH antagonist to the subject, suppressing sex hormones in a subject, reducing vasomotor symptoms or hot flashes in a subject, and reducing symptoms of decreased libido in a subject having uterine fibroids, endometriosis, or adenomyosis.

Abstract: A piston, in particular for a gear-change selector, including a piston body with a piston skirt and with a piston end face which can be pressurised with a working fluid. The piston includes a first sealing portion and a second sealing portion. The piston body and the first sealing portion have mutually complementary geometries so that they form a first vent channel. The first vent channel is arranged in a hydraulic series circuit with the second sealing portion. The second sealing portion prevents venting up to a first pressure and allows this above the first pressure. The invention furthermore concerns a gear-change selector and a gearshift for a vehicle.

Abstract: A fluidic device can include interconnected volumes including a bulk fluid volume fluidically connected in series with a capillary volume to receive a density gradient column, a reservoir of a reconstitution buffer positioned outside the interconnected volumes, and a buffer inlet chamber to receive reconstitution buffer from the reservoir of reconstitution buffer. The fluidic device can also include a reactant chamber connected to the buffer inlet chamber by a fluid channel, wherein the reactant chamber contains a reactant, and a reactant injection channel connecting the reactant chamber to the capillary volume to inject the reconstitution buffer and reactant into the capillary volume.

Abstract: A microfluidic valve can include a substrate having a microfluidic channel formed in the substrate. A sealing layer can be over the microfluidic channel. A flexible blister layer can be over the sealing layer. The flexible blister layer can include a blister formed as a distended portion with a blister volume between the flexible blister layer and the sealing layer. The microfluidic valve can be actuatable by puncturing the sealing layer by pressing on the blister. Actuating the microfluidic valve can either allow fluid to flow through the microfluidic channel or block fluid from flowing through the microfluidic channel.

Abstract: A handle for an oral-care implement, the handle comprises an electrical motor arranged to drive an output element structured and configured to couple the handle and a head attachable to and detachable from the handle; and a microcontroller for controlling the motor and to cause the output element to vibrate in (a) at least one oral-hygiene mode during which the oral-care implement is being used for an oral-hygiene routine, wherein the output element is vibrating at a substantially constant frequency, and (b) a disinfection mode during which the handle is being disinfected, before or after being used for the oral-hygiene routine, wherein the output element is continuously vibrating at a modulated frequency alternating within a frequency range of between about 140 Hz and about 250 Hz, for a duration of the disinfection mode.

Abstract: A handle for an oral-care implement for safe and hygienic use by multiple users includes an electrical motor and a detachable head. The handle has a display for displaying instructions to control functional operation of the handle, a microcontroller for controlling the motor and the display, and at least one switch to allow a user to control the functional operation of the handle, including causing the output element to vibrate in at least one oral-hygiene mode having an oral-hygiene frequency and causing the output element to vibrate in a disinfection mode when the handle is being disinfected before or after being used for the oral-hygiene routine. The disinfection mode has a modulated frequency, different from the oral-hygiene frequency, and alternating up and down between a low modulated frequency and a high modulated frequency, wherein the high modulated frequency is at least 50 percent greater than the low modulated frequency.

Abstract: A metered volume microfluidic device can include fluid flow microfluidics. The fluid flow microfluidics can include an inflow channel, a metered volume chamber positioned to receive working fluid from the inflow channel, a metered volume outflow channel positioned to receive and direct a metered volume of the working fluid when discharged from the metered volume chamber, and a capillary check valve. The capillary check valve can allow excess working fluid to exit the metered volume chamber when filling the metered volume chamber via the inflow channel. The capillary check valve can also prevent excess working fluid that has passed there through from being reintroduced into the metered volume chamber when the working fluid is discharged into the metered volume outflow channel.

Abstract: A print liquid supply apparatus or interface structure to be connected to a print system comprises a liquid channel, liquid interface and integrated circuit contact pads.

Abstract: The present disclosure is drawn to an ink supply tank for a printer. The ink supply tank includes a main chamber to supply a printer with ink. The main chamber includes a fill port to receive ink during filling and an exchange port to release the ink. A chamber separator device is configured with a fill surface and a vent port. An overflow chamber can be configured with a vent to pass air into the overflow chamber, a first portion of air in the overflow chamber passes through the vent port of the chamber separator device to a feeder chamber to replace a second portion of ink leaving the ink supply tank to feed a print head and the vent port of the chamber separator device to pass a third portion of ink and a second portion of air from the feeder chamber to the overflow chamber.