Abstract: Disclosed herein are compositions and methods of treating osteoporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I) or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.

Abstract: A two-part oral care system includes a first vessel containing an oxidative composition having a pH less than 7.5 and a second vessel containing a reductant composition having a pH greater than 7. The first and second vessels isolate the oxidative and reductant compositions from reacting with one another during storage and the vessels can dispense the oxidative and reductant compositions for combining to result in a final composition for use. The oxidative composition includes an ozonated oil and an oxidant. The reductant composition includes an aloe gel or aloe vera, a xylitol, a ferrous sulfate, a sodium bicarbonate, a calcium carbonate, a zinc gluconate, a salt comprising, a bromelain, a papain and at least one essential oil. A probiotic lozenge may also be used after the two-part oral care system to install good bacteria.

Abstract: The disclosure features, inter alia, methods and compositions for detecting, isolating, and/or analyzing one or more analytes such as, but not limited to, biomolecules (e.g., proteins, glycoproteins, lipids (e.g., sphingolipids), and carbohydrates). Such methods and compositions are useful in, e.g., the discovery of novel proteins, or the amino acid sequence of novel proteins, or identifying biomarkers for diseases such as cancer, immunological disorders, or microbial infections.

Abstract: A motor vehicle kinetic energy recovery system uses one or more cylinders of an internal combustion engine as the first or primary stage in a multi-stage high pressure air compression system, a compressed air storage system, compressed air operated drive train boosters and vehicle management electronics to provide cooperation between the air compression, storage and booster systems. The multi-stage, high pressure air compressor system is operable through engine compression braking allowing kinetic energy of a vehicle to be recaptured during retardation of vehicle speed.