Abstract: A near-field probe (and associated method) compatible with near-infrared electromagnetic radiation and high temperature applications above 300° C. (or 500° C. in some applications) includes an optical waveguide and a photonic thermal emitting structure comprising a near-field thermally emissive material coupled to or part of the optical waveguide. The photonic thermal emitting structure is structured and configured to emit near-field energy responsive to at least one environmental parameter of interest, and the near-field probe is structured and configured to enable extraction of the near-field energy to a far-field by coupling the near-field energy into one or more guided modes of the optical waveguide.

Abstract: An electrical system for a drug delivery device is proposed, the electrical system comprising an electrical liquid sensitive unit, wherein the electrical liquid sensitive unit comprises at least one liquid sensing arrangement, wherein the electrical liquid sensitive unit is configured to react to the exposure of the liquid sensing arrangement to liquid, and wherein the electrical system is configured to change its state from a normal state to an error state in response to the exposure of the at least one liquid sensing arrangement to liquid.

Abstract: The present disclosure relates to an encoder ring for a dose recording system of a drug delivery device. The encoder ring includes a support ring having a substantially circular configuration and includes a proximal end face and a distal end face. The encoder ring further includes a series of flag segments rigidly connected to each other via the support ring, wherein each flag segment has a substantially rectangular outer surface extending in a curved plane, and wherein at least one flag segment of the series of flag segments includes one or more of a retention clip and a positioning pin.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: Electronic system, user interface member, drug delivery device and method for detecting whether a drug delivery device is, or was, exposed to fluid In at least one embodiment, the electronic system is configured to compare measurements taken with a measurement (21) unit with a reference and to determine, based on the result of the comparison, an exposure of the drug delivery device to fluid. The measurements are suitable to provide information about the drug delivery device.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Abstract: The present disclosure is generally directed to an attachment mechanism suitable for attaching a module to an object, e.g. to a portion of a drug delivery device. Further, the disclosure is directed to an electronic system, e.g. an electronic add-on module, which is configured to be, e.g. releasably, attached to a drug delivery device as well as an assembly including the electronic add-on module as well as the drug delivery device. The attachment mechanism may include at least one attachment member with a longitudinal axis, an adhesive distal end surface and an opposite adhesive proximal end surface.

Abstract: An implantable neuromodulation system can include an electrode configured to be disposed at or near a first branch of a hypoglossal nerve of a patient and configured to provide a first electrostimulation therapy to treat a sleep disorder or breathing disorder of a patient. The system can include a sensor configured to provide a sensor signal that includes information about a patient response to the first electrostimulation therapy, information about a patient respiration, or information about one or more other physiologic status indicators for the patient. The sensor signal information can be used to quantify a progression of a breathing disorder for the patient.

Abstract: A cleaning roller is mountable to a cleaning robot. The cleaning roller includes a sheath comprising a shell, an outer diameter of the shell tapering from a first end portion of the sheath and a second end portion of the sheath toward a center of the roller. The cleaning roller further includes a core including a central portion interlocked with the sheath to rotationally couple the core to the sheath and inhibit relative translation of the sheath and the core along an axis of rotation. An inner surface of the sheath and an outer surface of the core define an air gap therebetween, the air gap extending from the central portion of the core longitudinally along the axis of rotation toward the first end portion or the second end portion.

Abstract: The invention concerns pharmaceutical compositions containing a hydrogen sulphate salt of 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and solvates, crystalline forms and amorphous forms thereof, to the use of said compositions as a medicament; and to processes for the preparation of said compositions.

Abstract: A nameserver receives a request to access a webpage from a client device. The nameserver generates a blockchain query based on the request for querying a domain registrar blockchain storing domain name registration data in smart contracts. The nameserver sends the first blockchain query to the domain registrar blockchain. In response to receiving a nameserver identifier from the domain registrar blockchain, the nameserver retrieves a DNS record for the webpage using the received nameserver identifier. The nameserver then provides information from the retrieved DNS record to the client device to allow the client device to access the webpage.

Abstract: A process and system to integrate a steam cracking unit with a blue ammonia unit such that a methane-rich gas stream and/or a hydrogen-rich gas stream is directed from the steam cracking unit to the blue ammonia unit while a hydrogen gas containing stream is directed from the blue ammonia unit to the steam cracking unit.

Abstract: A process and system for integrating a steam cracking unit with a blue hydrogen unit in which a methane-rich gas stream, a hydrogen-rich gas stream, or both from the steam cracking unit are fed to the blue hydrogen unit and a high purity hydrogen gas stream from the blue hydrogen unit is directed to the steam cracking unit.

Abstract: A system for controlling a steam cracking furnace may include a controller configured to control an electric heater to pre-heat a combustion air feed to a radiation section of the cracking furnace, and one or more sensors configured to sense properties of a recovered pure hydrogen stream fed to the radiation section of the cracking furnace as fuel. The controller can be configured to receive the sensed properties from the one or more sensors and control the electric heater based on the one or more sensed properties.

Abstract: An implantable neuromodulation system can include an electrode configured to be disposed at or near a first branch of a hypoglossal nerve of a patient and configured to provide a first electrostimulation therapy to treat a sleep disorder or breathing disorder of a patient. The system can include a sensor configured to provide a sensor signal that includes information about a patient response to the first electrostimulation therapy, information about a patient respiration, or information about one or more other physiologic status indicators for the patient. The sensor signal information can be used to quantify a progression of a breathing disorder for the patient.

Abstract: A system for treating exhaust gases from a combustion engine and a method for using the same results in improved NOx conversion during engine startup. The system includes a compact SCR flow-through monolith installed upstream of a close-coupled SCR wall-flow filter, wherein the compact SCR flow-through monolith may be extruded or made of a thin-walled substrate, such that the SCR flow-through monolith has a smaller volume with lower heat capacity and higher catalyst loading relative to the SCR wall-flow filter.

Abstract: A control unit for an access point via which access to a restricted area can be granted to a subject, the control unit comprising one or more processors configured to: determine a positional state of a subject in dependence on data captured by one or more imaging devices; determine a positional state of an access device; assess whether the subject is in possession of the access device; and determine whether the positional state of the subject and/or the access device matches a predetermined characteristic associated with an intention to enter the access point; and if (i) the subject is in possession of the access device, (ii) the positional state of the subject and/or the access device matches a predetermined characteristic associated with an intention to enter the access point and (iii) the subject is authorized to access the restricted area, output a signal to indicate to the access point that access to the subject is to be granted.

Abstract: A photodetector interface circuit is described, residing partially or fully within a unit cell per pixel of an FPA. The interface circuit uses an innovative approach to providing pixel level digitization for full frame integration times while maintaining the ability to use integration capacitors of practical sizes. The technique uses successive charge subtraction, removing charge from an integration capacitor successively, triggered by the charge increasing sufficiently to charge the integrator to a reference level, thereby triggering both charge removal and incrementing a count, until all of the current flowing in the photodetector has been accounted for and the count represents the digitization of the photodetector signal. Various options on how to arrange the digitization elements are also disclosed.

Abstract: An assembly for a drug delivery device is provided, the assembly comprising a feedback feature. The feedback feature is configured to indicate an end of the dispense operation to a user by giving an audible and/or tactile feedback.

Abstract: An electronic add-on module configured for releasable attachment to a drug delivery device is described. The electronic add-on module includes at least a body configured to be releasably attached to the device housing, a coupler configured to be releasably attached to the device dial grip, and a dial configured to be axially displaceable with respect to the coupler. The electronic add-on module further includes a tube which is configured to be permanently rotationally constrained to the body and configured to be axially displaceable relative to the body wherein the dial is configured to be rotatable relative to the tube at least in a dialing mode.