Abstract: The technology described herein is directed to a food assembly and packaging robot for automating aspects of food assembly and packaging. The food assembly and packaging robot system may include a robot system include a conveyance system, a bowl dispenser, one or more food dispensers, one or more condiment dispensers, a lidder, and a bagger, and in some instances, other components. The bowl dispenser may be configured to deposit bowls onto the conveyance system. The one or more food dispensers may be configured to deposit one or more ingredients into the bowls and the one or more condiment dispensers may be configured to deposit one or more condiments into the bowls. The lidder may be configured to position lids atop the bowls and the bagger may be configured to place the bowls into bags.

Abstract: The present application provides methods of treating hidradenitis suppurativa in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of a compound which inhibits JAK1 and/or JAK2, or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to an active polling method. The method comprises steps of creating (302), by an intrusion detection system, a bi-directional connection between at least one backup system and the intrusion detection system. The method further comprises generating (304) a pre-flight care query to initiate an active polling session and querying (306) the at least one backup system using it before initiating the active polling session. The method further comprises receiving (308) a response from the at least one backup system and initiating (310) the active polling session for the at least one node of the distributed control system if the response is negative or stalling (312) the active polling session for a pre-set time of the at least one node of the distributed control system if the response is affirmative.

Abstract: An image capture device that includes a housing; a heat generating component enclosed by internal surfaces of the housing; and a first heatsink and a second heatsink that are each simultaneously and thermally connected with the heat generating component. One or both of the first and second heatsinks positioned on an external surface of the housing.

Abstract: A beverage dispense apparatus and associated method, comprises a frame (11) for removably locating and holding a sealed beverage unit package (C) in a vertical orientation. A first piercing element (14) punctures a vent opening into a headspace of the beverage package (C) and, subsequently as the first piercing element is driven downward, a second piercing element (15) punctures an outlet opening into the beverage package so that beverage can flow through a nozzle (17) under gravity. An ultrasonic transducer (16) against the nozzle (17) may supply excitation energy that breaks gas out of solution so that a creamy head is formed on the beverage in a delivery vessel underneath the frame. Control of the vent opening/vale (13) enables flow to be slowed or stopped through the nozzle (17) enabling a settle time and “two-part” pour.

Abstract: The present disclosure relates generally to apparatus, devices, and methods for increasing force distribution at a suture-tissue interface. In some embodiments, a tissue suturing device may include a deployment device and a plurality of tissue supports deployable from the deployment device towards a target tissue. The plurality of tissue supports may each include a central opening for receiving a suture during deployment.

Abstract: Medical devices and methods for using medical devices are disclosed. Example fluid reservoirs and tube sets arranged and configured to couple to an endoscope for use in an endoscopic procedure are disclosed. An example fluid reservoir and tube set includes a fluid reservoir configured to contain a fluid, a fluid supply tube configured to be coupled to the endoscope and having a lumen extending therethrough, wherein the lumen is in fluid communication with the fluid reservoir and a first backflow prevention mechanism coupled to the fluid supply tube, the first backflow prevention mechanism configured to permit fluid to flow through the fluid supply line from the fluid reservoir to the endoscope and to prevent fluid from flowing back through the fluid supply tube from the endoscope to the fluid reservoir.

Abstract: This disclosure relates to JAK1 pathway inhibitors and their use in treating vitiligo.

Abstract: This disclosure relates to ruxolitinib, or a pharmaceutically acceptable salt thereof, and its use in treating prurigo nodularis.

Abstract: The invention refers to a method for producing expanded polymer pellets, which comprises the following steps: melting a polymer comprising a polyamide; adding at least one blowing agent; expanding the melt through at least one die for producing an expanded polymer; and pelletizing the expanded polymer. The invention further concerns polymer pellets produced with the method as well as their use, e.g. for the production of cushioning elements for sports apparel, such as for producing soles or parts of soles of sports shoes. A further aspect of the invention concerns a method for the manufacture of molded components, comprising loading pellets of an expanded polymer material into a mold, and connecting the pellets by providing heat energy, wherein the expanded polymer material of the pellets or beads comprises a chain extender. The molded components may be used in broad ranges of application.

Abstract: A firearm with a slide and a frame. The slide has a slide rail. The frame has a frame rail. The frame rail interfaces with the slide rail. The frame rail has a lubrication groove and a debris removal port. The lubrication groove extends along a surface of the frame rail that bears against the slide rail during operation of the firearm. The debris removal port has gap within the frame rail proximate to an end of the lubrication groove.

Abstract: An agent delivery device comprises: one or more agent containers at a proximal end of the agent delivery device, wherein the one or more agent containers are configured to contain one or more fluids; an insertion section comprising a tube defining one or more lumens, the insertion section coupled to the agent containers such that the one or more fluids may flow from the agent containers to the one or more lumens and out of one or more outlets of the one or more lumens; and a distal impingement structure at the distal end of the insertion section, the distal impingement structure comprising an impingement surface arranged relative to one or more outlets to impinge the one or more fluids dispensed from the one or more outlets to cause mixing of the one or more fluids for application of the fluids at a treatment site.

Abstract: A clipping system includes an adapter, a clip and a first extending member. The clip includes first and second jaws which are movable between an insertion configuration and an initial deployed configuration. The jaws are biased toward the initial configuration. The first member is releasably coupled to the clip and movably connected to the adapter. The first member includes a distal end releasably coupled to the first jaw such that longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial configuration and a review configuration. The first member is operable to retract the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter. A first releasable link connects the first member to the clip and releases when the first member is subject to a force exceeding a predetermined threshold value.

Abstract: The present disclosure relates to materials and systems to manage thermal runaway issues in energy storage systems. Exemplary embodiments include an insulation layer that is placed in the encapsulation material used to encapsulate a pouch battery cell. The encapsulation layer for a pouch battery cell is made from a laminate film that comprises an insulation layer.

Abstract: A pouring attachment device for a disposable package of nitrogenated beverage, e.g. an aluminium can P, that achieves a desirable foam head when the beverage is poured into a glass. The attachment comprises a main body or housing (11), an ultrasonic wave generator (27) and a means to couple the device to the package, such as a rim seal (2)0. A flow channel has a contoured inlet (26) configured for communicating beverage from the package to an outlet (21), via a resonance chamber (28), and is particularly configured for minimising turbulence.

Abstract: A medical device may comprise a handle, wherein the handle includes a movable body and a main body; a cap configured to be coupled to a distal end of a scope; a patch, wherein the patch is moveable relative to the cap; and a petal body. The patch may be removably coupled to the petal body. The medical device may further comprise an actuator body coupling the patch to the moveable body such that movement of the moveable body extends the patch from the cap. The petal body may be configured to transition between a closed configuration in which the patch is retracted, and an open configuration in which the patch is extended radially-outward from a central longitudinal axis of the scope.

Abstract: A medical device may include a needle, including a plurality of links and a distal tip, reciprocally movable between a first configuration and a second configuration, and a conduit including a lumen extending through the needle, the conduit being coupled to the distal tip, wherein longitudinal movement of the conduit is configured to transition the needle between the first configuration and the second configuration.

Abstract: A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.

Abstract: The technology described herein is directed to a food assembly and packaging robot for automating aspects of food assembly and packaging. The food assembly and packaging robot system may include a robot system include a conveyance system, a bowl dispenser, one or more food dispensers, one or more condiment dispensers, a lidder, and a bagger, and in some instances, other components. The bowl dispenser may be configured to deposit bowls onto the conveyance system. The one or more food dispensers may be configured to deposit one or more ingredients into the bowls and the one or more condiment dispensers may be configured to deposit one or more condiments into the bowls. The lidder may be configured to position lids atop the bowls and the bagger may be configured to place the bowls into bags.