Abstract: An accessory device for use with a medical device includes a first cuff secured to a distal end of the medical device, a second cuff secured to the medical device proximal of the first cuff, an actuator, and at least one actuation wire extending from the first cuff, through the second cuff, to the actuator.

Abstract: A medical device includes a longitudinal portion with one or more tubes, a distal portion with one or more arms, and one or more actuation mechanisms. The one or more arms each includes an arm lumen. Each arm lumen is connected to a respective tube, and at least one of the longitudinal portion and the distal portion is configured to be coupled to a distal end of an insertion device. The one or actuation mechanisms are movable to transition one or more arms from a closed configuration to an open configuration.

Abstract: A medical device comprising a shaft, a handle including a proximal portion and a distal portion, wherein the distal portion is fixed to a proximal portion of the shaft, and a channel extending from the handle into the shaft, wherein the channel includes a proximal channel and a distal channel, the proximal channel being rotatable relative to the distal channel and aligned with the distal channel throughout rotation of the proximal channel, wherein the proximal portion includes the proximal channel and the distal portion includes the distal channel, wherein the distal portion is rotatable relative to the proximal portion of the handle, and the shaft is configured to rotate with the distal portion of the handle.

Abstract: A method for coupling a first medical device component to a second medical device component comprising altering the first medical device component from a natural state to an altered state, by reducing a cross-sectional dimension of the first medical device, fitting a first portion of the first medical device component in the altered state into a first opening of the second medical device component, wherein the first medical device component includes second portions not within the first opening of the second medical device component, and allowing the second portions of the first medical device component to revert back to the natural state.

Abstract: An emulator configured to emulate an automated aircraft assembly jig supporting an aircraft assembly is disclosed. The emulator connectable to an automated equipment module and configured to: send a first signal to an automated equipment module, wherein the first signal is representative of a communication to the automated equipment module; and receive a second signal from the automated equipment module representative of a communication from the automated equipment module, wherein the automated equipment module is arranged to operate autonomously on an aircraft assembly.

Abstract: A device for administering a fluid to a patient anatomy includes a flexible catheter. The catheter includes a lumen extending therethrough. The catheter is sized and shaped to extend from a proximal end outside a human body to a distal end that can be guided to a target location. A distal portion of the catheter includes one or more exit ports communicating with a first lumen for administering the fluid. A deformable portion of the catheter is formed so that, in a first state, the deformable portion assumes a first shape suitable for guiding the catheter to the target location and, in a second state, the deformable portion assumes a second shape in which the deformable portion curves to extend in at least one radial direction for engaging an inner wall of the target location to anchor the catheter in the target location while administering the fluid.

Abstract: A device includes a flexible catheter and a material. The catheter includes at least a first channel extending therethrough and is sized and shaped to extend from a proximal end outside a human body to a distal end that can be guided to a target location within a gastrointestinal (GI) system. A first distal portion of the catheter includes at least one exit port communicating with the first channel for administering a fluid to a patient anatomy. The material is fixed to an exterior of the catheter or ejectable from an interior of the catheter into the location that, in a first state or shape, is suitable for guiding the catheter to the location and, in a second state or shape, is suitable for engaging an inner wall of the location to anchor the catheter in the location while administering the fluid via the first channel.

Abstract: A device includes a flexible catheter and at least one wirefrom. The catheter includes a first lumen extending therethrough and is sized and shaped to extend to a target location within a gastrointestinal (GI) system. A first distal portion of the catheter includes one or more exit ports communicating with the first lumen for administering a fluid to the location. The wireform is attached around the catheter or deployable from within the catheter, the wireform being formed so that, in a first state, the wireform assumes a first shape suitable for guiding the catheter to the location and, in a second state, the wireform assumes a second shape in which the wire extends away from the catheter in at least one radial direction for contacting a wall of the location to anchor the catheter in the location while administering the fluid via the first lumen.

Abstract: This invention provides a system for supporting and unwinding/paying out wire from multiple spools, including a framework for supporting the plurality of wire spools. A mount is constructed and arranged to attach to mobile equipment, such as a skid steer. The framework includes forward extended beams that support a plurality of removable axles. There are axles adapted to rotatably retain a plurality of spools of wire therealong. A plurality of removable sleeves are located along each of the axles that retain the spools, respectively, against motion therealong. A levelling assembly allows the axles to tilt relative to an angle at which the equipment is disposed. The spools can be held laterally along each respective axle by clamping sleeves/spacers.

Abstract: A trisamide compound has the structure of Formula (I) in which R1, R2, and R3 are independently selected from the group consisting of alkyl groups. A polymer composition comprises a trisamide compound of Formula (I) and a polyolefin polymer. The polymer compositions containing a trisamide compound of Formula (I) exhibit very low haze levels and minimal extraction of the trisamide compound.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first engagement member having a first end and a second end, a second engagement member having a first end and a second end, a first elastic member attached to the second end of the first engagement member, and a first alignment member having a first end, a second end and a lumen extending therethrough. Further, the tissue retraction device has a first length, the first alignment member has a second length, the first elastic member extends within the lumen of the first alignment member and the second length of the first alignment member is less than or equal to the first length of the tissue retraction device.

Abstract: Methods and systems for operating an aircraft engine. A health parameter for the engine received from a first instrument is monitored by a health evaluation device communicatively coupled to a communication link between an engine controller and a second instrument which generates an operation parameter signal indicative of an engine operating condition. The health parameter is compared, by the health evaluation device, to a predetermined threshold. When the health parameter is below the threshold, the health evaluation device causes the operation parameter signal to be transmitted from the second instrument to the controller. When the health parameter reaches the threshold, the health evaluation device prevents the operation parameter signal from being transmitted from the second instrument to the controller, and transmits to the controller a fault signal to elicit a health response therefrom, the fault signal containing at least two mutually-exclusive fault codes associated with the operating condition.

Abstract: A sequence data processing and retention method includes obtaining sequence data produced by a sequencer device. The sequence data includes genomic data of interest and metadata. The method processes the sequence data, and this processing includes separating the genomic data of interest from the metadata, and compressing the separated genomic data of interest based on a reference sequence to produce compressed genomic data The method additionally stores storing the compressed genomic data and the metadata. Optionally, based on a request, a process recovers the sequence data from the stored compressed genomic data and metadata, where the recovering includes decompressing the compressed genomic data to provide decompressed genomic data of interest as the separated genomic data of interest, and combining the decompressed genomic data of interest with the metadata to provide combined genomic data and metadata.

Abstract: In 6G, there are multiple radios that can cover the same location at any time, and yet radio failure can occur. However, a mobile edge computing (MEC) platform can increase the footprint of adjacent radios to compensate for a failed radio. To reduce the failure interruption and maintain a quality of experience for a subscriber, the MEC can utilize a virtual session capability to communicate radio change of service characteristics to a service provider. Consequently, the change in service characteristics can comprise an expanded coverage area for adjacent radios such that a mobile device of the subscriber can take advantage of the expanded coverage area without experiencing an interruption in service.

Abstract: A medical device, comprising a fastening assembly, wherein the fastening assembly includes an adapter defining an opening therethrough, a fastener releasably coupled to the adapter, wherein the fastener includes at least two jaws pivotable relative to one another, the fastener having a first configuration wherein the jaws are open and a second configuration wherein the jaws are closed, and at least one cable coupled to the fastener and the adapter, the at least one cable being configured to apply tension to the fastener to transition between the first configuration and the second configuration while the fastener is coupled to the adapter, and to control release of the fastener from the adapter.

Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, the capsule releasably coupled to a proximal portion of the device and clip jaws, proximal ends of which are slidably received within the channel of the capsule so that the clip jaws are movable between an open configuration and a closed configuration. Clip jaws are configured so that a distance between the distal ends of the clip jaws in an open configuration is between 15 and 18 millimeters. Clip jaws further include barbs extending from a distal portion thereof.

Abstract: This disclosure relates to JAK1 pathway inhibitors and their use in treating prurigo nodularis.

Abstract: Unlike smart devices, Internet of things (IoTs), such as meter readers, generate very low revenue per user. Traditional tunnel/bearer based connection-oriented architectures do not scale economically for billions of IoT devices due to the amount of signaling overhead associated with GTP tunnel setup/tear down and the states related to GTP tunnels maintained at various parts of the mobile network. However, the mobility network can efficiently support massive stationary and/or mobile IoTs by reducing the amount of signaling overhead, the state of the IoTs kept in network, and simplifying the data plane when possible.

Abstract: A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Abstract: A system identifying an area of interest of an inspection surface is disclosed. A controller includes a machine learning model trained using stored images defining an area of interest on the inspection surface. A laser projector for projecting laser indicia onto the inspection surface is spatially located relative to the inspection surface enabling the laser projector to project the laser indicia onto the area of interest. An imager includes an image sensor system generates a current image of the inspection surface and signals the current image to the controller. The machine learning model is directed to the area of interest of the current image as identified by the laser indicia and the machine learning model implementing the neural network to inspect the current image of the area of interest as defined by the laser indicia enabling localized inspection of the inspection surface.