Abstract: Surgical instruments for interfacing with implants can include an inserter configured to dock to a unilateral portion of an implant. The inserter can include a control shaft that is configured to lock or unlock the inserter coupling with the implant. Actuation of the control shaft can occur by way of a knob that can control movement of the control shaft. The inserter can facilitate positioning of the implant relative to a surgical site and allow for application of counter-torque when imparting torque for tightening a set screw, etc. Additional instruments can also be used to manipulate the implant. For example, auxiliary instruments can be coupled to the inserter, such as a reducer instrument, to facilitate rod reduction, etc. Alternatively or in addition, a holder instrument can be used that has a threaded distal engagement feature for coupling to the implant to facilitate positioning thereof.

Abstract: An armrest center console for a vehicle includes a housing defining a storage bin, a track assembly having a first and second tracks provided on opposite sides of the housing, and an armrest cover assembly supported on the housing and having a deployable table. The armrest center console also includes a linkage assembly coupling the armrest cover assembly to the first and second tracks, wherein the armrest cover assembly is configured to slide forward on the first and second rail and to rotate upward via the linkage assembly to deploy the deployable table.

Abstract: A nonwoven fabric. The nonwoven fabric can include a first surface and a second surface and a visually discernible pattern of three-dimensional features on one of the first or second surface. Each of the three-dimensional features can define a microzone comprising a first region and a second region. The first and second regions can have a difference in values for an intensive property, and wherein in at least one of the microzones the first region exhibits a Contact Angle of greater than 90 degrees, as measured by the Contact Angle Test Method detailed herein.

Abstract: Modular connectors and methods are disclosed that provide two sides of a connector in modular and interchangeable fashion. The modular design can be enhanced to add various useful features to one or both sides of the connectors, including the use of rods, hooks, rod receivers of various configurations, etc. This modular approach can allow the assembly of various unique connectors from a pool of components that are interchangeable while minimizing manufacturing cost and complexity.

Abstract: A package of personal care articles. Each of the personal care articles has a nonwoven substrate as a component. The nonwoven substrate can have a first surface defining a plane of the first surface and a non-regular pattern of a plurality of three-dimensional features extending outwardly from the plane of the first surface. The non-regular pattern can include a first zone of first three-dimensional features and a second zone of second three-dimensional features, wherein in at least one of the first or second zones of the plurality of three-dimensional features has a first three-dimensional feature having a first intensive property and a second three-dimensional feature having a second, different intensive property. The personal care articles can be compressed in the package.

Abstract: Fibrous structures, for example sanitary tissue products, such as toilet tissue, and more particularly fibrous structures containing a movable surface and methods for making same and methods for making same are provided.

Abstract: Fibrous structures containing filaments and solid additives, and more particularly to fibrous structures containing filaments and solid additives wherein the fibrous structure has three or more regions that exhibit different characteristics and/or properties and methods for making same, are provided.

Abstract: Fibrous structures containing a surface care composition, and more particularly dry fibrous structures containing a surface care composition comprising one or more bacteriophage, methods of making same, and methods for treating surfaces using same are provided.

Abstract: The present disclosure relates to nanobodies, such as defined by SEQ ID NOS: 1-54, which may be encoded by SEQ ID NOS: 55-110, and which are capable of specifically binding glycoprotein VI (GPVI), as well as uses thereof, which include therapeutic and/or imaging uses.

Abstract: A method assessing tissue morphology using machine learning includes a step of training a machine learnable device to predict the status of a diagnostic feature in stained tissue samples. The machine learnable device is trained with a characterized set of digital images of stained tissue samples. Each digital image of the characterized set has a known status for the diagnostic feature and an extracted feature map provides values for a extracted feature over an associated 2-dimensional grid of spatial locations. A step of inputting the set of extracted feature maps is inputted into the machine learnable device to form associations therein between the set of extracted feature maps to and the known status for the diagnostic feature to form a trained machine learnable device. The status for the diagnostic feature of a stained tissue sample of unknown status for the diagnostic feature is predicted from the trained machine learnable device.

Abstract: A system includes a dome, a wiper assembly, a position sensor and a control device. The wiper assembly includes a wiper blade configured to rotate around the dome. The position sensor may be configured to send a signal to a control device when a wiper blade passes the position sensor. The control device may include one or more processors configured to receive the signal from the position sensor and determine a location of the wiper blade relative to the dome based on the received signal.

Abstract: Intelligent impedance injection modules (IIM)s are currently being used for line balancing and overcoming local disturbances on High Voltage (HV) transmission lines of an HV power grid. These distributed IIMs are connected and/or coupled to the HV transmission lines and operate with a pseudo ground at the voltage of the HV transmission line. In order to operate effectively, the IIMs need to communicate with other distributed IIMs across the three phases of the HV grid and also communicate with local intelligent centers LINCs that connect to and synchronize operations across each group of the distributed IIMs in a local region of the HV power grid. Systems and methods are presented for effective and secure sub-cyclic speed communication to and from the distributed IIMs, distributed IIMs to LINCs and substations to enable coordinated actions. Further the distributed IIMs and LINCs receive GPS signals and use the GPS clock for synchronizing operations.

Abstract: A storage assembly for a vehicle includes a console housing including a storage compartment and an access opening to the storage compartment. The storage assembly includes a tambour door assembly having a tambour door panel configured to move between a first position to close the access opening and a second position to open the access opening. The storage assembly also has a tray assembly including the tambour door panel. The tray assembly is configured to move between a retracted position and an extended position relative to the console housing.

Abstract: Provided are methods of treatment involving immunotherapy, such as T cell therapy, and administration of a tryptophan metabolism and/or kynurenine pathway modulator. In some embodiments, the method includes a combination therapy that involves administration of engineered T cells, such as chimeric antigen receptor (CAR)-expressing cells, and a tryptophan metabolism and/or kynurenine pathway modulator, such as an inhibitor of an enzyme. Also provided are engineered cells in which the expression of a molecule involved in the kynurenine pathway is modified. Also provided are methods of manufacturing engineered cells, cells, compositions, methods of administration to subjects, nucleic acids and kits for use in the methods. In some aspects, features of the methods and cells provide for increased or improved activity, activity, outcome, function, response, persistence, expansion and/or proliferation of cells for adoptive cell therapy.

Abstract: Generally, this disclosure enables various mounting interfaces, devices therewith, accessories therefor, and methods of manufacture and use thereof. In particular, these mounting interfaces include a latch configured to engage with a detent of an accessory (e.g., a smartphone, a dedicated navigation device, a storage container, a drinking bottle) in order to (a) allow the accessory to be easily mounted thereon and unmounted therefrom and (b) hold the accessory sufficiently securely when the accessory is mounted thereon.

Abstract: Fibrous structures containing filaments and optionally, solid additives, wherein the pre-moistened fibrous structures exhibit wet compressive modulus values that are superior to known pre-moistened fibrous structures as measured according to the Wet Compressive Modulus Test Method described herein and methods for making same are provided.

Abstract: An absorbent article is disclosed. The article includes a topsheet formed of a section of formed nonwoven web material having an ordered arrangement of zones, each zone comprising one or more attenuated regions adjacent to one or more built-up regions, wherein the attenuated regions have a first average basis weight and the built-up regions have a second average basis weight, wherein the first average basis weight is less than the second average basis weight, the difference in basis weights corresponding to disposition of the filaments according to the ordered arrangement. The attenuated region(s) may include a plurality of discrete low bulk portions arranged in a pattern disposed along a longitudinal axis of the article, which facilitate z-direction movement of fluid through the topsheet and inhibit spreading of a fluid stain along the topsheet in the x and y directions.

Abstract: An article including a stack of layers including a high refractive index layer and a low refractive index layer; wherein at least one layer of the stack includes a wavelength selective absorbing material; and wherein the stack of layers has a transparent region with an edge at a wavelength in which light is absorbed by the wavelength selective absorbing material, and a reflection band with an edge at a wavelength in which light is reflected is disclosed. Compositions and optical devices including the article are also disclosed. Additionally, there is disclosed a method of making the article, the composition, and the optical device.

Abstract: The present disclosure relates to fibrous structures including active agents and having a graphic printed thereon. In some embodiments, a nonwoven web may include a fibrous structure comprising filaments. In turn, the filaments may include filament forming material, and an active agent releasable from the filaments when exposed to conditions of intended use. In addition, a graphic may be printed directly onto the fibrous structure.

Abstract: A portable container has a payload chamber for holding goods and a lid operable to access the payload chamber. The portable container also has an electronic system with one or more power storage devices, circuitry that wirelessly communicates via a cell radio with a cloud-based data storage system or a remote electronic device, and an electronic display screen. The electronic system also has a button or a touch screen configured to be actuated by a user to a) automatically switch sender and recipient information on the electronic display screen to facilitate return of the portable container to the sender or b) automatically contact a parcel carrier to alert the parcel carrier that the portable container is ready for pickup.