Abstract: This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs).

Abstract: The present disclosure generally relates to user interfaces and techniques for monitoring fitness activity. In accordance with some embodiments, user interfaces and techniques for transitioning between a user interface mode for measuring an activity metric to a user interface mode for measuring a different activity, based on detecting that a user characteristic has changed, are described. In accordance with some embodiments, user interfaces and techniques for measuring activity data and providing activity commentary in response to activity-based events, where different activity commentary is provided based on a characteristic of a user, are described.

Abstract: The present invention relates to compositions and methods for treating cancer, particularly to agents that inhibit the expression and/or activity of the protein second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI (SMAC/Diablo). The inhibiting agents include RNA interference molecules silencing the expression of SMAC/Diablo and peptides modulating its interactions within the cell nucleus and mitochondria. The methods and agents of the present invention are useful in treating cancers associated with overexpression of SMAC/Diablo.

Abstract: Disclosed are methods of preparing an isolated population of dendritic cells, isolated populations of dendritic cells prepared by the methods, and pharmaceutical compositions comprising the isolated population of dendritic cells. Also disclosed are methods of treating or preventing cancer using the isolated population of dendritic cells or pharmaceutical compositions.

Abstract: An oil containment system and installation method for a transformer mounted on a transformer pad, comprising a plurality of interlocking open-topped containment units. Each of the containment units having a base, a sump formed with two vertically-aligned sidewalls, a first end, and a second end. The sidewalls have support struts extending across the sump and a grate member. At least one of the ends includes a connecting member or a receiving member, the connecting member sized to be placed within the receiving member sized to interlock adjacent containment units. A discriminative outlet is disposed within an opening in the sidewall and includes a filtration media for adsorbing oil from a fluid and subsequently blocking oil flow through the discriminative outlet. The interlocking containment units are secured to the transformer pad around a peripheral edge to restrict the migration of oil to an outside portion of said oil containment system.

Abstract: Embodiments disclosed herein include temperature control systems. In an embodiment, a temperature control system comprises a fluid reservoir for holding a fluid, and a spray chamber fluidically coupled to the fluid reservoir. In an embodiment, a pump is between the spray chamber and the fluid reservoir, where the pump provides the fluid to the spray chamber. In an embodiment, the temperature control system further comprises a vacuum source fluidically coupled to the spray chamber, where the vacuum source controls a pressure within the spray chamber, and where the fluid reservoir is between the vacuum source and the spray chamber.

Abstract: As may be implemented in accordance with one or more aspects characterized herein, a wall patch is adhered to a wall surface having a damaged region. The wall patch has a base layer and a plurality of layers of transparent material stacked on the base layer, with the base layer being visible through the transparent material and therein aligned around the damaged region. A surface coating is applied to an area of the wall surface around the wall patch and to the wall patch, after which a top removable layer of the wall patch is removed to expose a top surface of an underlying one of the layers. A further coating is applied to the exposed top surface of the underlying layer, and to the area of the wall surface around the wall patch.

Abstract: Disclosed are systems and methods for updating of a machine learning model on a vehicle. A data processing system having at least one processor coupled with memory can predict a first value for a characteristic of the vehicle based at least on a model and measure a second value for the characteristic of the vehicle based at least on a sensor of the vehicle. The data processing system can determine a difference between the first value predicted based at least on the model and the second value measured is greater than a tolerance. The data processing system can identify a state of the vehicle associated with the difference between the first value and the second value and provide, in response to the difference determined greater than the tolerance, the state of the vehicle to a server remote from the vehicle to update the model.

Abstract: A vertically-elongated member, which is preferably a support post used in a molten metal pump, includes a ceramic tube and tensioning structures to add a compressive load to the tube along its longitudinal axis. This makes the tube less prone to breakage. Another vertically-elongated member, such as a support post, includes one or more reinforcement members to help alleviate breakage. A device, such as a pump, used in a molten metal bath includes one or more of such vertical members.

Abstract: Mechanical modifications to a spinal rod that will enable the rod to accept various coating technologies in such a way that the spinal construct's biomechanical performance is not compromised. These modifications preserve construct biomechanics in the presence of a coating and increase the bactericidal payload of an anti-infective spinal rod coating.

Abstract: A hydraulic system for controlling bleed down and retraction of a boom within a safety envelope includes a backup battery power supply, and at least a first boom lift hydraulic cylinder configured to raise and lower the boom. The first boom lift hydraulic cylinder includes a solenoid bleed valve electrically connected to the backup battery power supply. The hydraulic system also includes an input device controllable by an operator of the boom. The input device may, for instance, be used by the operator to initiate bleed down and retraction of the boom from an elevated position. To accommodate independent failsafe features of the system, the input device is configured to selectively actuate the solenoid bleed valve using electrical power supplied from the backup battery power supply.

Abstract: A method and apparatus to detect breaks in tracks and/or detect the presence of a vehicle, such as a train, in a monitored section of the track or rail. Embodiments of the present invention measure the change in track inductance associated with a track or rail break. Electrical shunts are connected between the rails at spaced-apart intervals (for example a shunt can be placed every mile). At least two different frequencies of alternating current are generated and fed into the segments of rail (for example at or near a mid-point between the shunts). If a rail break occurs, the total inductance of the rail at that segment will change. Using two or more frequencies allows a rail break to be differentiated from environmental rail-to-rail and rail-to-earth leakage.

Abstract: A connector for attachment of two frame elements in a framing system has a connector body of similar rectangular section to the frame elements. A flat inner engagement face of the connector body engages with a flat end face of a first frame element, and essentially forms an extension of the first frame element. An outer engagement face of the connector body is substantially parallel to the inner engagement face and in use abuts against a flat side wall of a second frame element. The outer engagement face has two outwardly projecting lips along opposite side edges of the connector body at the outer face. Each lip has a curved inner face for engagement with opposed radiused edges at opposite sides of the flat side wall face of the second frame element. A flat outer face of the lip forms an extension of a side wall of the connector body and provides a smooth transition between adjacent side walls of the two frame elements.

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Abstract: There is provided a paper for packaging of medical devices comprising 5-25 wt. % (dry) synthetic fibres comprising polyester and 2.0-12.0 wt. % (dry) of a latex binder or 1.0-5.0 wt. % (dry) of a starch binder, wherein the length of the synthetic fibres is 8-14 mm and the thickness of the synthetic fibres is 5.5-9.0 dtex and wherein the paper has a grammage according to ISO 536:2012 of 70-110 g/m2.

Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Abstract: A data management system includes: a transceiver; a memory; and a processor communicatively coupled to the transceiver and the memory and configured to: receive, via the transceiver, a copy data request for unstructured data; access, via the transceiver in response to the copy data request, a plurality of backed-up files of unstructured data stored in a first data storage device; send, in response to the copy data request, a plurality of Virtual Data Files (VDFs) to a second data storage device, the processor being configured to respond to receipt of information from each of the plurality of VDFs to retrieve a respective backed-up file of unstructured data of the plurality of backed-up files of unstructured data stored in the first data storage device.

Abstract: Prosthetic heart valves and anchors for use with such valves are provided that allow for an improved implantation procedure. In various embodiments, an anchoring device is formed as a coiled or twisted anchor that includes one or more turns that twist or curve around a central axis. One or more arms attached to the frame of the valve guide the anchoring device into position at the native valve as it exits the delivery catheter, and the expandable prosthetic valve is held within the coil of the anchoring device. The anchoring device and the valve can be delivered together, simplifying the valve replacement procedure.

Abstract: The invention relates to carbonate-linked surface modifying macromolecules and admixtures thereof. The admixtures can be used in industrial and medical applications where enhanced surface properties are desirable (e.g., surface properties reducing or preventing biofouling, immobilization of biomolecules, or denaturation of certain biomolecules).

Abstract: Examples described herein provide a method that includes receiving engine data from a sensor associated with the engine. The method further includes associating a header with the engine data to generate packaged engine data. The method further includes transmitting the packaged engine data to an aircraft communication unit, wherein the header provides for the aircraft communication unit to transmit the packaged engine data to a ground station communication unit via a communication protocol.