Patents by Inventor Pei FAN

Pei FAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200317772
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Another embodiment of this invention relates to the antibodies binding fragments thereof described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.
    Type: Application
    Filed: February 3, 2020
    Publication date: October 8, 2020
    Inventors: Andrew Lawrence FELDHAUS, Leon GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katie Olson ANDERSON, Ethan Wayne OJALA, Pei FAN, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Jeffrey T.L. SMITH, John LATHAM
  • Publication number: 20200281557
    Abstract: The present disclosure is related to systems and methods for monitoring a medical device. The medical device may include a tube configured to generate radiation rays and a detector configured to receive radiation rays emitted from the tube. The tube may include an anode target and a filament. The detector may include a plurality of detecting units. The method may include obtaining imaging data acquired by the detector via detecting radiation rays emitted from the tube. The method may also include determining a first feature parameter associated with the radiation rays based on the imaging data. The method may further include monitoring the medical device based on the first feature parameter associated with the radiation rays.
    Type: Application
    Filed: May 22, 2020
    Publication date: September 10, 2020
    Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Tao HE, Jiawen ZHOU, Zhouyuan FAN, Bing LI, Pei ZHOU
  • Publication number: 20200238263
    Abstract: A method for preparing a bi-component, multi-network nanofibrous aerogel-supported heterojunction photocatalyst includes the following steps. Step 1, preparing ammoniated polyacrylonitrile nanofibers. Step 2, dispersing the ammoniated polyacrylonitrile nanofibers in water to obtain a first solution; dispersing cellulose nanofibers in water to obtain a second solution; and mixing, heating and lyophilizing the first solution with the second solution to obtain a bi-component, multi-network nanofibrous aerogel. Step 3, adding graphite carbon nitride, a ferric-iron containing reagent, 2,5-diaminoterephthalic acid, and the bi-component, multi-network nanofiber aerogel obtained in the step 2 into a N, N-dimethylformamide solvent to obtain a third solution, and carrying out a hydrothermal reaction on the third solution for 8-24 hours to obtain the bi-component, multi-network nanofibrous aerogel-supported heterojunction photocatalyst.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 30, 2020
    Applicant: NANJING UNIVERSITY
    Inventors: Fuqiang LIU, Jinli QIU, Pei FAN, Cailiang YUE, Ranran YUAN, Aimin LI
  • Publication number: 20200227818
    Abstract: An RF energy transmitting apparatus with positioning and polarization tracing function is used for an RF energy harvesting apparatus. The RF energy transmitting apparatus includes a power radar transmitter and a radar controller. The power radar transmitter receives a power source signal and emits an electromagnetic source wave. The radar controller is electrically connected to power radar transmitter and receives a reflected harmonic wave. The power radar transmitter emits the electromagnetic source wave to scan a space. The RF energy harvesting apparatus generates and emits the reflected harmonic wave. The radar controller determines a position and a polarization angle of the RF energy harvesting apparatus after receiving the reflected harmonic wave and to adjust a polarization angle of the power radar transmitter to be within a predetermined angle range with respect to the polarization angle of the reflected harmonic wave sent from the RF energy harvesting apparatus.
    Type: Application
    Filed: April 1, 2020
    Publication date: July 16, 2020
    Inventors: Tzuen-Hsi HUANG, Sheng-Fan YANG, Chun-Cheng CHEN, Pei-Jung CHUNG, Fang-Ming WU
  • Publication number: 20200181229
    Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 11, 2020
    Inventors: Maria-Cristina Loomis, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katherine Lee Hendrix, Ethan W. Ojala, Pei Fan, Jeffrey T.L. Smith, John A. Latham, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Vanessa Lisbeth Rubin, Jens J. Billgren
  • Publication number: 20200181230
    Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 11, 2020
    Inventors: Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katherine Lee HENDRIX, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • Publication number: 20200172611
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Embodiments of this invention relate to the binding fragments of antibodies described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.
    Type: Application
    Filed: December 9, 2019
    Publication date: June 4, 2020
    Inventors: Andrew Lawrence Feldhaus, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katie Olson Anderson, Ethan Wayne Ojala, Pei Fan, Charlie Karasek, Jenny A. Mulligan, Danielle Marie Mitchell, Patricia Dianne McNeill, Michelle L. Scalley-Kim, Erica Stewart, Jeffrey T.L. Smith, John Latham
  • Publication number: 20200172612
    Abstract: The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies inhibit, block or neutralize at least one biological effect associated with PACAP, e.g., vasodilation. In exemplary embodiments these antibodies and antigen binding fragments thereof may comprise specific VH, VL, and CDR polypeptides described herein. In some embodiments these antibodies and antigen binding fragments thereof bind to and/or compete for binding to specific epitope(s) on human PACAP. The invention is further directed to using these antagonistic anti-PACAP antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with PACAP and conditions where antagonism of PACAP-related activities, such as vasodilation, mast cell degranulation, and/or neuronal activation, are therapeutically beneficial, e.g., headache and migraine indications.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 4, 2020
    Inventors: Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katherine Lee HENDRIX, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • Publication number: 20200165316
    Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.
    Type: Application
    Filed: February 11, 2020
    Publication date: May 28, 2020
    Inventors: Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katherine Lee HENDRIX, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • Patent number: 10660601
    Abstract: The present disclosure is related to systems and methods for monitoring a medical device. The medical device may include a tube configured to generate radiation rays and a detector configured to receive radiation rays emitted from the tube. The tube may include an anode target and a filament. The detector may include a plurality of detecting units. The method may include obtaining imaging data acquired by the detector via detecting radiation rays emitted from the tube. The method may also include determining a first feature parameter associated with the radiation rays based on the imaging data. The method may further include monitoring the medical device based on the first feature parameter associated with the radiation rays.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: May 26, 2020
    Assignee: SHANGHAI UNITED IMAGING HEALTCARE CO., LTD.
    Inventors: Tao He, Jiawen Zhou, Zhouyuan Fan, Bing Li, Pei Zhou
  • Patent number: 10644393
    Abstract: An RF energy transmitting apparatus is applied to an RF energy harvesting apparatus, the RF energy transmitting apparatus includes: a power radar transmitter receiving a power source signal and emits an electromagnetic source wave. A radar controller is electrically connected to the power radar transmitter and receives a reflected harmonic wave. After receiving the electromagnetic source wave, the RF energy harvesting apparatus generates and emits the reflected harmonic wave. After the radar controller receives the reflected harmonic wave, the radar controller determines a polarization angle of a reflection signal from the RF energy harvesting apparatus, and the radar controller adjusts the polarization angle of the antenna of the power radar transmitter to be within a predetermined range around the polarization angle of the reflected harmonic signal from the RF energy harvesting apparatus for an optimal received power.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: May 5, 2020
    Assignees: DELTA ELECTRONICS, INC., NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Tzuen-Hsi Huang, Sheng-Fan Yang, Chun-Cheng Chen, Pei-Jung Chung, Fang-Ming Wu
  • Patent number: 10624013
    Abstract: In an approach for converging a cloud computing environment and a mobile device into an integrated environment, a processor receives a request to complete a computing task on a first device, wherein the computing task requires a physical sensor. A processor determines that the computing task should be offloaded from the first device to a second device based, at least in part, on the first device lacking the physical sensor and the second device having the physical sensor. A processor offloads the computing task from the first device to the second device. A processor receives a result of the computing task from the second device.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: April 14, 2020
    Assignee: International Business Machines Corporation
    Inventors: Pei Xing Ji, Xue Ling Mi, Yun Qi Li, Yan Lu, Xiang Zhou, Jin Fan Zhu
  • Patent number: 10607974
    Abstract: A micro LED display and a manufacturing method thereof are disclosed. A plurality of electrode structures is formed on a first surface of a substrate, and a plurality of circuit structure are formed in the substrate, where the circuit structures are electrically connected to the electrode structures. An LED functional layer is formed on the substrate, and includes a plurality of mutually isolated LED functional structures, where the LED functional structures are corresponding and electrically connected to the electrode structures. An electrode layer covers the LED functional layer and is electrically connected to the LED functional structures. Micro lenses are formed on the electrode layer and corresponding to the LED functional structures. Therefore, all the LED functional structures can be wholly used as a light-emitting region of a pixel, improving light emission efficiency of the micro LED display.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: March 31, 2020
    Assignee: OMNIVISION SEMICONDUCTOR (SHANGHAI) CO., LTD.
    Inventors: Regis Fan, Pei-Wen Ko, Chun-Sheng Fan
  • Publication number: 20200079847
    Abstract: The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies inhibit, block or neutralize at least one biological effect associated with PACAP, e.g., vasodilation. In exemplary embodiments these antibodies and antigen binding fragments thereof may comprise specific VH, VL, and CDR polypeptides described herein. In some embodiments these antibodies and antigen binding fragments thereof bind to and/or compete for binding to specific epitope(s) on human PACAP. The invention is further directed to using these antagonistic anti-PACAP antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with PACAP and conditions where antagonism of PACAP-related activities, such as vasodilation, mast cell degranulation, and/or neuronal activation, are therapeutically beneficial, e.g., headache and migraine indications.
    Type: Application
    Filed: January 8, 2019
    Publication date: March 12, 2020
    Inventors: Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katherine Lee HENDRICKS, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • Publication number: 20200062837
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.
    Type: Application
    Filed: July 8, 2019
    Publication date: February 27, 2020
    Inventors: Benjamin H. Dutzar, Brian R. Kovacevich, Patricia Dianne McNeill, Danielle M. Mitchell, Ethan W. Ojala, Pei Fan, Jens J. Billgren, Erica A. Stewart, Corinne C. Akatsuka, Betty Yu-Ching Chang, John A. Latham, Leon F. Garcia-Martinez
  • Patent number: 10574542
    Abstract: The present invention provides a method and system for distributing resources for operating applications within a network by determining a composite resource consumption of the network of resources distributed throughout the network, and determining minimum, maximum and average values of each of the resources required to operate the applications. When an application is introduced into, or removed from, the network, then a change in the composite resource consumption of the network is determined and a software patch is generated to adjust resource distribution throughout the network so that resource allocation to active applications is normalized for optimal operation.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: February 25, 2020
    Assignee: International Business Machines Corporation
    Inventors: Pei Xing Ji, Yun Qi Li, Yan Lu, Xiang Zhou, Jin Fan Zhu, Jia Zhu
  • Publication number: 20200059116
    Abstract: A radio frequency energy-harvesting apparatus is applied to a radio frequency energy-transmitting apparatus with a location detection function. The radio frequency energy-harvesting apparatus includes a direct current signal receiving-processing unit, a rectification and harmonic generation unit, and a radar wave receiving-transmitting unit. The rectification and harmonic generation unit is electrically connected to the direct current signal receiving-processing unit. The radar wave receiving-transmitting unit is electrically connected to the rectification and harmonic generation unit.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Inventors: Tzuen-Hsi HUANG, Sheng-Fan YANG, Chun-Cheng CHEN, Pei-Jung CHUNG, Chun-Yi LU
  • Patent number: 10550180
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Another embodiment of this invention relates to the antibodies binding fragments thereof described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: February 4, 2020
    Assignee: ALDERBIO HOLDINGS LLC
    Inventors: Andrew Lawrence Feldhaus, Leon Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katie Olson Anderson, Ethan Wayne Ojala, Pei Fan, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Jeffrey T. L. Smith, John Latham
  • Publication number: 20200031916
    Abstract: Antibodies and antibody fragments thereof with binding specificity to human Nerve Growth Factor (NGF) and methods of use for treating pain. Methods of treating pain or eliciting an analgesic effect comprising administering an effective amount of an anti-human NGF antibody or antibody fragment thereof, which inhibits the association of NGF with TrkA, and/or p75. These methods may optionally further comprising administering an effective amount of a second anti-human NGF antibody or fragment thereof (e.g., one which inhibits the association of NGF with p75, or one that inhibits the association of NGF with TrkA.
    Type: Application
    Filed: March 11, 2019
    Publication date: January 30, 2020
    Inventors: Leon F. Garcia-Martinez, John Latham, Ethan W. Ojala, Corinne C. Akatsuka, Pei Fan, Jeffrey T.L. Smith, Benjamin H. Dutzar
  • Patent number: 10544214
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Embodiments of this invention relate to the binding fragments of antibodies described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: January 28, 2020
    Assignee: ALDERBIO HOLDINGS LLC
    Inventors: Andrew Lawrence Feldhaus, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katie Olson Anderson, Ethan Wayne Ojala, Pei Fan, Charlie Karasek, Jenny A. Mulligan, Danielle Marie Mitchell, Patricia Dianne McNeill, Michelle L. Scalley-Kim, Erica Stewart, Jeffrey T. L. Smith, John Latham