Abstract: A phase-shift unit includes: a first substrate and a second substrate provided opposite to each other; a medium layer provided between the first substrate and the second substrate; a microstrip line disposed at a side of the second substrate facing towards the first substrate; and a grounding layer provided at a side of the first substrate facing towards the second substrate and formed with a via hole; wherein a projection of the via hole onto the second substrate and a projection of the microstrip line onto the second substrate have an overlapped area therebetween; and wherein the via hole is configured to feed a phase-shifted microwave signal out of the phase-shift unit, or feed a microwave signal into the phase-shift unit such that the microwave signal is phase-shifted.

Abstract: Provided herein are compositions and methods for treating cancers using anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4) antibodies, such as activatable anti-CTLA4 antibodies. In some embodiments, combination therapies including an anti-CT-LA4 antibody and an immune checkpoint inhibitor, an anti-CD137 antibody, a vascular endothelial growth factor (VEGF) inhibitor, a chemotherapeutic agent, or a poly ADP ribose polymerase (PARP) inhibitor are provided.

Abstract: Through the hybridoma technique, we got two hybridoma cells secreting anti-CTLA-4 mAb with high affinity, which were named 22G11 and 16C11 respectively. To construct the chimeric antibody light chain and heavy chain expression vectors, the cloned anti-CTL4 antibody's light chain (VL) and heavy chain variable region cDNAs (VH) were respectively fused to the human antibody light and heavy chain constant region genes (CH). Then appropriate light and heavy chain expression vectors were co-transfected into CHO-K1 cells and the clones producing the highest amount of chimeric antibodies were selected. In the end, the purity of the two chimeric antibodies was more than ninety percent. Both of them can bind Jurkat cells specifically as did the commercial anti-CTLA-4 mAb. Western blotting analysis showed that mAbs 22G11 and 16C11 reacted with one specific band with a molecular weight of about 22 kD, further indicating that 22G11 and 16C11 specifically recognized CTLA-4 molecule.

Abstract: This application provides an array substrate, a display apparatus, and an electronic device. The display apparatus includes a plurality of microcup units. Each of the microcup units includes at least one microcup. Electrophoretic particles are encapsulated in each of the at least one microcup. The array substrate includes a first base, a plurality of pixel units arranged in an array on the first base, and an insulating layer. The plurality of pixel units are in one-to-one correspondence to the plurality of microcup units. Each of the pixel units includes a first pixel electrode and a first common electrode. The insulating layer covers the first pixel electrode and the first common electrode of each of the pixel units.

Abstract: An adjustable strand threading and lubricating device for prefabricated box girders includes an underframe. Multiple first spline shafts are rotatably installed between left and right side walls of the strand threading boxes. The first openings are respectively located above the first spline shafts, first sliding blocks are respectively provided and configured to slide up and down in the first openings, multiple second spline shafts is rotatably installed between two first sliding blocks, and axes of the second spline shafts are parallel to the first spline shafts. The first spline shafts and the second spline shafts are slidably provided with multiple strand threading units for threading steel strands, a lubricating unit is arranged on a front side of the strand threading units, and a bundling unit is arranged on a rear side of the strand threading units.

Abstract: This application provides a display and a terminal device. The display includes a cover plate, a composite display layer, and a first substrate from top to bottom, where the composite display layer includes an ink filling laver and an emissive display module layer the emissive display module layer includes a plurality of pixels, each pixel includes an effective light transmitting zone and a non-effective light transmitting zone, and the effective light transmitting zone includes an emissive luminescent material: the ink filling layer includes a first zone corresponding to the effective light transmitting zone and a second zone corresponding to the non-effective light transmitting zone, and the second zone is filled with an electronic ink material.

Abstract: A removal-facilitated anchor sealing device for box girder construction is provided and includes a base; wheels are mounted below the base; a forward direction of the wheels is designated as a front side; a main box body is arranged on a top surface of the base in a manner of sliding back and forth; an interior of the main box body is divided into anchor sealing chambers from bottom to top through separation plates; a front side of each anchor sealing chamber is opened; anchor sealing units are arranged in the anchor sealing chamber in sequence in a left-right direction; a spraying unit is arranged below the anchor sealing units; working ends of the anchor sealing units and working end of the spraying unit extend out of the anchor sealing chamber from the front side; a storage unit is arranged on a top surface of the main box body.

Abstract: A vehicle includes a plurality of areas, each of the plurality of areas includes at least one light emitting apparatus and at least one sensor of a first type, the plurality of areas include a first area, the first area includes a first light emitting apparatus and a first sensor, and a type of the first sensor is the first type. A light system control method includes: obtaining a first signal collected by the first sensor; and controlling, based on the first signal, the first light emitting apparatus to work.

Abstract: Embodiments of this application provide a method for controlling variable transmittance glass. The method includes: obtaining an elevation angle and a yaw angle of a light source, where the elevation angle indicates an included angle between a direction in which light of the light source is emitted to the target vehicle and a horizontal plane, and the yaw angle indicates an included angle between a connection line between a projection of the light source on the horizontal plane and a centroid of the target vehicle, and a driving direction of the target vehicle; obtaining location information of a target object; obtaining a projection area projected by the target object on the variable transmittance glass based on the location information of the target object, and the elevation angle and the yaw angle of the light source, where the target object is located in the target vehicle.

Abstract: Provided herein are libraries containing synthetic polynucleotides that encode activatable binding polypeptides. Further provided herein are activatable binding polypeptides and polypeptide libraries containing such activatable binding polypeptides. Also provided herein are vectors, vector libraries, cells, kits, and methods of making and using activatable polypeptide libraries.

Abstract: Provided herein are cross-reactive antibodies (or antigen binding fragments thereof) that bind to human CTLA4, activatable antibodies that bind to human CTLA4, nucleic acid molecules encoding the same, pharmaceutical compositions thereof, and methods of their therapeutic use (e.g., for treatment of cancer).

Abstract: Provided herein are libraries containing synthetic polynucleotides that encode activatable binding polypeptides. Further provided herein are activatable binding polypeptides and polypeptide libraries containing such activatable binding polypeptides. Also provided herein are vectors, vector libraries, cells, kits, and methods of making and using activatable polypeptide libraries.

Abstract: This application relates to the field of intelligent vehicle technologies, and in particular, provides a control method, a control apparatus, and the like for an odor adjustment system, to improve user experience. A target odor type of a to-be-released gas is determined based on scene information such as driving fatigue scene information, schedule reminder information, driving mode information, music scene information, or environment information, and the to-be-released gas having the determined target odor type is released, to adjust an odor of an environmental space.

Abstract: A liquid crystal phase shifter, a liquid crystal antenna, a communication apparatus, and a method for operating a liquid crystal phase shifter are provided. The liquid crystal phase shifter includes a microwave transmission structure and a phase adjustment structure opposite to each other, and a liquid crystal layer between the microwave transmission structure and the phase adjustment structure; wherein the phase adjustment structure comprises a plurality of phase adjustment units; the plurality of phase adjustment units are configured to change a dielectric constant of the liquid crystal layer according to a voltage applied to the phase adjustment units and a voltage applied to the microwave transmission structure, so as to adjust a phase of a microwave signal; and phase shift amounts adjusted by at least two of the plurality of phase adjustment units are different from each other.

Abstract: A biological detection chip, a biological detection device, and a detection method thereof are disclosed. The biological detection chip includes a first base substrate and a plurality of detection units arranged in an array along a row direction and a column direction on the first base substrate. Each of the plurality of detection units includes a thin film transistor and an electrode, the thin film transistor is on the first base substrate and includes a gate electrode, a source electrode, and a drain electrode, and the electrode is on a side of the thin film transistor away from the first base substrate and is connected to the drain electrode, and the electrode is configured to carry a biological material to be detected.

Abstract: There is provided a liquid crystal phase shifter including first and second substrates opposite to each other, and a liquid crystal layer between the first and second substrates. The first substrate includes a first base plate and a first electrode layer at a side of the first base plate proximal to the liquid crystal layer. The second substrate includes a second base plate and a second electrode layer at a side of the second base plate proximal to the liquid crystal layer. The first electrode layer includes a main body structure having a first side and a second side opposite to each other with respect to an extension direction of the main body structure, and a plurality of branch structures connected to at least one of the first side and the second side of the main body structure. The second electrode layer includes a plurality of first fingers.

Abstract: Provided are antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, and for the treatment of cancer.

Abstract: A liquid crystal antenna unit and a liquid crystal phased array antenna are provided. The liquid crystal antenna unit includes: a first substrate, a second substrate opposite to the first substrate, a liquid crystal layer between the first substrate and the second substrate, a transmission line on a first surface and extending in a first direction along the first surface, a first antenna oscillator on the first surface and arranged as an elongated dipole extending in a second direction along the first surface, a second antenna oscillator on a surface of the second substrate distal to the first substrate and at a position corresponding to the first antenna oscillator, and a ground electrode on a surface of the first substrate distal to the second substrate.

Abstract: There is provided a liquid crystal phase shifter including first and second substrates opposite to each other, and a liquid crystal layer between the first and second substrates. The first substrate includes a first base plate and a first electrode layer at a side of the first base plate proximal to the liquid crystal layer. The second substrate includes a second base plate and a second electrode layer at a side of the second base plate proximal to the liquid crystal layer. The first electrode layer includes a main body structure having a first side and a second side opposite to each other with respect to an extension direction of the main body structure, and a plurality of branch structures connected to at least one of the first side and the second side of the main body structure. The second electrode layer includes a plurality of first fingers.

Abstract: A poor foundation reinforcement system and a reinforcement method based on underground concealed arch structures are provided. The system and the method belong to the technical field of poor foundation treatment. The reinforcement system includes multiple columns of pile foundations arranged along a bridge direction. Multiple arch sheets are set in parallel between each two adjacent columns of pile foundations. Each arch sheet includes multiple high-pressure rotary jet piles arranged along the bridge. Each two adjacent arch sheets of the multiple arch sheets are connected by a micro-bending slab disposed on the two adjacent arch sheets, the multiple arch sheets are connected by the micro-bending slabs to together form an arch ring, and a construction joint is disposed between each two adjacent micro-bending slabs of the micro-bending slabs.