Abstract: A method can include receiving input for a multiwell pad; selecting, based at least in part on a portion of the input, a template for the multiwell pad; generating, based at least in part on the template, well trajectories for the multiwell pad, where each of the well trajectories extends from a surface location of the multiwell pad to one or more reservoir target locations and where each of the well trajectories includes at least one curve generated using one or more dogleg severity values and one or more geometric control points that are not required to lie on one or more of the well trajectories; and outputting specifications for the generated trajectories of the multiwell pad.

Abstract: A method of preventing a collision of a subject wellbore in a downhole environment includes receiving offset wellbore data corresponding with one or more offset wellbores and identifying, based on the offset wellbore data, one or more no-go zones for each of the one or more offset wellbores. The method further includes determining a plurality of safe points corresponding with a potential intersection of the subject wellbore with the one or more no-go zones and, defining an escape zone within the plurality of safe points. The method further includes determining a trajectory for the subject wellbore within the escape zone.

Abstract: A method may include receiving input for a multiwell structure and subsurface target locations, where the multiwell structure includes slots; generating, based at least in part on the input, a position for the multiwell structure, slot-well assignments for the slots, and well trajectories, where each of the well trajectories extends from an assigned one of the slots to one or more of the subsurface target locations; and outputting a set of specifications for the position for the multiwell structure, the well trajectories, and an order for drilling the well trajectories.

Abstract: A method can include receiving input for a multiwell pad; selecting, based at least in part on a portion of the input, a template for the multiwell pad; generating, based at least in part on the template, well trajectories for the multiwell pad, where each of the well trajectories extends from a surface location of the multiwell pad to one or more reservoir target locations and where each of the well trajectories includes at least one curve generated using one or more dogleg severity values and one or more geometric control points that are not required to lie on one or more of the well trajectories; and outputting specifications for the generated trajectories of the multiwell pad.

Abstract: A magnetic bead, and a preparation method therefor and the use thereof in nucleic acid extraction. The preparation method for a magnetic bead comprises: preparing a magnetic core by means of a water-soluble salt of Fe2+ and Fe3+; and subjecting the magnetic core and a silanide to a modification reaction to obtain the magnetic bead, wherein the molar ratio of the addition amount of the used silanide to the total amount of Fe2+ and Fe3+ is greater than or equal to 0.5:1, and the particle size range of the magnetic bead is 0.1-50 ?m.

Abstract: The disclosure provides a method for preparing ultra-low molecular weight Dendrobium oligosaccharides by enzymatic hydrolysis and its application, and belongs to the technical field of bioengineering. In the disclosure, Thermobifida halotolerans-derived glycosidases are recombined to an Escherichia coli expression system to realize high activity expression. The recombinantly expressed ThDPS enzyme can hydrolyze Dendrobium polysaccharides, and produced oligosaccharide products mainly include ultra-low molecular weight (<1000 Daltons) Dendrobium disaccharides, Dendrobium trisaccharides, Dendrobium tetrasaccharides and Dendrobium pentasaccharides, and low-molecular weight (<10000 Daltons) Dendrobium hexaoses, Dendrobium heptaoses and Dendrobium octacoses, and higher Dendrobium oligosaccharide products.

Abstract: This disclosure relates to uses of inhibitors of YTH family proteins in the management of fragile X syndrome, fragile X-associated disorders, cognitive disorders, developmental disorders, or central nervous system (CNS) disorders. In certain embodiments, this disclosure relates to treating fragile X syndrome, fragile X-associated disorders, cognitive disorders, developmental disorders, or central nervous system (CNS) disorders by administering an effective amount of an inhibitor of YTHDF1 to a subject in need thereof. In certain embodiments, the YTHDF1 inhibitor is a small molecule inhibitor such as salvianolic acid C, derivatives, prodrugs, esters, or salts thereof.

Abstract: A coating device includes a first coating mechanism configured to coat a first surface of a substrate, a first oven drying mechanism arranged downstream of the first coating mechanism, a second coating mechanism arranged downstream of the first oven drying mechanism and configured to coat a second surface of the substrate opposite to the first surface, and a second oven drying mechanism arranged downstream of the second coating mechanism. The coating device further includes a third oven drying mechanism arranged downstream of the second oven drying mechanism and configured to further oven dry the coating on the second surface such that the coating on the first surface and the coating on the second surface are evenly dried.

Abstract: A guiding connection structure is configured to implement mutual guiding connection between a plug-in part installed on a first object and a plug-in part installed on a second object. The guiding connection structure includes a guide pin and a guide sleeve for guiding insertion of the guide pin. The guide pin is installed on the first object, and the guide sleeve is installed on the second object. An inner hole path of the guide sleeve includes a variable-diameter section. A hole diameter of the variable-diameter section gradually increases from one end of the variable-diameter section to the other end of the variable-diameter section. When the guide pin is inserted into the guide sleeve, the guide pin is inserted into the other end of the variable-diameter section from the one end of the variable-diameter section.

Abstract: This invention presents an ocean observation platform with an integrated, highly reliable wave energy generation mechanism, relevant to power supply technology in marine environments. It includes a platform floating body and a power generation mechanism located at the platform's bottom. The mechanism features disassemblable power generation piles, arranged in a circular array on the floating body. This design ensures that if one pile fails, the others continue generating electricity, enabling a long-term, stable, and continuous power supply. This is particularly useful for monitoring meteorological, temperature, salinity, and ocean current data in complex marine conditions.

Abstract: The present application provides an oven drying apparatus and a coating device. The oven drying apparatus comprises an oven drying chamber and a heating assembly. The oven drying chamber is equipped with a first oven drying side having a plurality of first air inlet portions for fluid medium to enter the oven drying chamber. The heating assembly is disposed on the first oven drying side. The first oven drying side is further provided with at least one air return portion provided between two adjacent first air inlet portions, and the air return portion being configured for fluid medium in the oven drying chamber to be discharged from the oven drying chamber. The arrangement of an air return portion between two first air inlet portions can discharge fluid medium between the two first air inlet portions and take away the heat, thus avoiding accumulation of heat between the two first air inlet portions.

Abstract: A method and system for finding and efficiently evaluating and selecting a wellbore path that accounts for placement rules and the presence of existing wells. A topological representation of the connected paths is created and managed. The topological representation may be generated as a pre-computed database of space information that represents the locations of existing wells and accounts for restrictions such as anti-collision and the parameters, including geological and drilling equipment parameters. Using such a representation, the design of a wellbore path may be completed quickly and more efficiently. The topology may represent all connected space for a section of the subsurface. This topological representation may be used to evaluate all possible paths from the starting point (surface location, tie-in point for a sidetrack, tie-in point for replanning, etc.) to the target and enable selecting the path that meets the conditions and is optimized for the existing constraints.

Abstract: This application relates to a conveyor and a baking device. A traction rope may bring an electrode plate to move in a transport space. The traction rope may be of high flexibility and can more smoothly bring the electrode plate to move in various complex environments such as an arcuate oven, thereby effectively avoiding derailment or jamming of the conveyor in the oven and conveying the electrode plate more smoothly in the oven.

Abstract: This application relates to a conveyor and a baking device. A traction rope may bring an electrode plate to move in a transport space. The traction rope may be of high flexibility and can more smoothly bring the electrode plate to move in various complex environments such as an arcuate oven, thereby effectively avoiding derailment or jamming of the conveyor in the oven and conveying the electrode plate more smoothly in the oven.

Abstract: A combination of at least one basic compound, such as potassium hydroxide, together with at least one aldehyde donor can synergistically scavenge mercaptans from organic fluids, such as hydrocarbons, where “synergistically effective” is defined as the amount of mercaptans scavenged is greater as compared with a combination where either the basic compound or the reaction product is absent, used in the same total amount.

Abstract: A coating device includes a first coating mechanism configured to coat a first surface of a substrate, a first oven drying mechanism arranged downstream of the first coating mechanism and configured to oven dry a coating on the first surface, a second coating mechanism arranged downstream of the first oven drying mechanism and configured to coat a second surface of the substrate opposite to the first surface, a second oven drying mechanism arranged downstream of the second coating mechanism and configured to oven dry a coating on the second surface, and a third oven drying mechanism arranged downstream of the second oven drying mechanism and configured to oven dry the coating on the second surface.

Abstract: A method can include receiving input for a multiwell pad; selecting, based at least in part on a portion of the input, a template for the multiwell pad; generating, based at least in part on the template, well trajectories for the multiwell pad, where each of the well trajectories extends from a surface location of the multiwell pad to one or more reservoir target locations and where each of the well trajectories includes at least one curve generated using one or more dogleg severity values and one or more geometric control points that are not required to lie on one or more of the well trajectories; and outputting specifications for the generated trajectories of the multiwell pad.

Abstract: The present application provides an oven drying apparatus and a coating device. The oven drying apparatus comprises an oven drying chamber and a heating assembly. The oven drying chamber is equipped with a first oven drying side having a plurality of first air inlet portions for fluid medium to enter the oven drying chamber. The heating assembly is disposed on the first oven drying side. The first oven drying side is further provided with at least one air return portion provided between two adjacent first air inlet portions, and the air return portion being configured for fluid medium in the oven drying chamber to be discharged from the oven drying chamber. The arrangement of an air return portion between two first air inlet portions can discharge fluid medium between the two first air inlet portions and take away the heat, thus avoiding accumulation of heat between the two first air inlet portions.

Abstract: A heat dissipation apparatus is provided. The apparatus includes: a bracket assembly including an accommodation portion used for accommodating a heat source component, a first opening, and a second opening; a heat sink. A heat conducting protrusion is disposed on a first surface of the heat sink, and the heat conducting protrusion extends into the accommodation portion through the second opening; and guide grooves are respectively provided in two side surfaces of the heat sink, and an extension direction of the guide grooves is inclined toward the first surface in an insertion direction of the heat source component; and fastening assemblies, each including a connecting member and a pressing member, where the pressing members are disposed on two sides of the bracket assembly, one end of the connecting member is slidably assembled in a guide groove located on a same side, and the other end abuts against a pressing member.