Publication number: 20240108784
Abstract: A hydrogel for cell-laden bioprinting, bioink, and a preparation method and an application thereof, relates to the technical field of biomedical polymer hydrogels. The hydrogel for cell-laden bioprinting is polymer gel formed by adding a cell-specific material into a matrix of alginate and gelatin and crosslinking and curing, wherein the cell-specific material is polypeptide selected according to different laden cells. The structures printed using the hydrogel may have the advantages such as adjustable mechanical properties, adjustable porosity, high biocompatibility, high printing accuracy, and high customizability, which may widely support the printing of human tissues and organs such as spinal cord, cartilage, and heart, and has good prospects for applications in tissue repair, organ transplantation and so on.
Type:
Application
Filed:
December 15, 2022
Publication date:
April 4, 2024
Applicants:
SHANDONG UNIVERSITY, YANSHAN UNIVERSITY
Inventors:
Chuanzhen HUANG, Zhuang CHEN, Hanlian LIU, Peng YAO, Zhenyu SHI, Dun LIU, Hongtao ZHU, Bin ZOU, Zhen WANG, Minting WANG, Longhua XU, Shuiquan HUANG, Meina QU, Zhengkai XU, Yabin GUAN
Patent number: 11946374
Abstract: The disclosure relates to an omni-directional horizontally oriented deflecting tool for a coiled tubing, which includes an inner central pipe, an outer central pipe, a conical outer cylinder, a piston outer cylinder, an anchoring mechanism, a sealing mechanism, a reversing mechanism and a steering mechanism. The anchoring mechanism includes a cone, an O-shaped sealing ring I, a cone spring, a slip, a slip spring, a slip seat, a claw I and a pin shaft I, and the sealing mechanism includes a piston, an O-shaped sealing ring II, a claw II, a pin shaft II, an upper rubber cylinder seat, a rubber cylinder, a connecting cylinder, a lower rubber cylinder seat and a gasket.
Type:
Grant
Filed:
July 5, 2023
Date of Patent:
April 2, 2024
Assignee:
Southwest Petroleum University
Inventors:
Yang Tang, Miantao Guan, Yulin Zhang, Peng Zhao, Guorong Wang, Jinhai Zhao, Qingyou Liu, Jinzhong Wang, Xiang Gao, Yufa He, Hu Deng, Liming Fan, Rutao Ma