Abstract: System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes. The system also includes a signal processor configured to receive the electrical signals to generate filtered signals, the filter configured to attenuate at least signals having frequencies corresponding to heart muscle activity during a heartbeat. The signal processor is also configured to identify a skin nerve activity using the filtered signals, estimate a sympathetic nerve activity using the identified skin nerve activity, and further to generate a report indicative of the estimated sympathetic nerve activity. In some aspects, the system further includes a signal generator to deliver the electrical stimulation to the subject's skin.

Abstract: System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes. The system also includes a signal processor configured to receive the electrical signals from the signal detector, and apply a filter to the received electrical signals to generate filtered signals, the filter configured to attenuate at least signals having frequencies corresponding to heart muscle activity during a heartbeat. The signal processor is also configured to identify a skin nerve activity using the filtered signals, estimate a sympathetic nerve activity using the identified skin nerve activity, and further to generate a report indicative of the estimated sympathetic nerve activity. In some aspects, the system further includes a signal generator to deliver the electrical stimulation to the subject's skin.

Abstract: A system and methods utilizing electrical stimulation to achieve a desired therapeutic effect are provided. In one aspect, a method for controlling nerve activity in a subject is provided. The method includes receiving input indicating a desired therapeutic effect for at least one neural structure of a subject, and selecting, based on the input received, an electrical stimulation configured to achieve the desired therapeutic effect. The method also includes controlling a sympathetic nerve activity in the subject by delivering the electrical stimulation using electrodes positioned proximate to nerves innervating the subject's skin.

Abstract: A system and method for diagnosing a sleep disorder in a subject are provided. In some aspects, the method includes sensing electrical signals corresponding to a skin nerve activity in the subject using a plurality of skin electrodes, and generating, using signal detector, signal data using the electrical signals. The method also includes assembling a time-series of data indicating the skin nerve activity using the signal data, and identifying a sleep disorder using the time-series of data. The method further includes generating a report indicative of the sleep disorder.

Abstract: An image sensor including a first pixel circuit, a second pixel circuit, a first readout line, a second readout line, a first readout circuit, a second readout circuit and an average switch is provided. The first and second pixel circuits are in two columns of a pixel array. The first readout line transmits pixel data of the first pixel circuit to the first readout circuit. The second readout line transmits pixel data of the second pixel circuit to the second readout circuit. The average switch is arranged between the first and second readout lines and used to electrically connect the first and second readout lines in an average mode to average the pixel data on the first and second readout lines.

Abstract: A system and methods utilizing electrical stimulation to achieve a desired therapeutic effect are provided. In one aspect, a method for controlling nerve activity in a subject is provided. The method includes receiving input indicating a desired therapeutic effect for at least one neural structure of a subject, and selecting, based on the input received, an electrical stimulation configured to achieve the desired therapeutic effect. The method also includes controlling a sympathetic nerve activity in the subject by delivering the electrical stimulation using electrodes positioned proximate to nerves innervating the subject's skin.

Abstract: System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes. The system also includes a signal processor configured to receive the electrical signals from the signal detector, and apply a filter to the received electrical signals to generate filtered signals, the filter configured to attenuate at least signals having frequencies corresponding to heart muscle activity during a heartbeat. The signal processor is also configured to identify a skin nerve activity using the filtered signals, estimate a sympathetic nerve activity using the identified skin nerve activity, and further to generate a report indicative of the estimated sympathetic nerve activity. In some aspects, the system further includes a signal generator to deliver the electrical stimulation to the subject's skin.

Abstract: A chip package with at least eight pins includes a main body, seven first pins and a second pin. An integrated circuit is disposed inside the main body. The seven first pins are electrically connected with the integrated circuit and configured to provide specific functions. The second pin is electrically connected with the integrated circuit and disposed adjacent by some of the seven first pins. The second pin is a free pin and unconnected with a passive component. The second pin is applied for empty connection, switch of detection accuracy, printing actuation or page turning.

Abstract: A system and method for monitoring nerve activity in a subject. The system includes a plurality of electrodes placed in proximity to skin of the subject, an amplifier electrically connected to the electrodes and configured to generate a plurality of amplified signals corresponding to electrical signals received from the subject through the electrodes, and a signal processor. The signal processor applies a high-pass filter to the amplified signals to generate filtered signals from the amplified signals, identifies autonomic nerve activity in the plurality of filtered signals; and generates an output signal corresponding to the filtered signals. The high-pass filter attenuates a plurality of the amplified signals having frequencies that correspond to heart muscle activity during a heartbeat.

Abstract: An image sensor including a first pixel circuit, a second pixel circuit, a first readout line, a second readout line, a first readout circuit, a second readout circuit and an average switch is provided. The first and second pixel circuits are in two columns of a pixel array. The first readout line transmits pixel data of the first pixel circuit to the first readout circuit. The second readout line transmits pixel data of the second pixel circuit to the second readout circuit. The average switch is arranged between the first and second readout lines and used to electrically connect the first and second readout lines in an average mode to average the pixel data on the first and second readout lines.

Abstract: The present disclosure illustrates a trigger circuit applied to an electronic apparatus having a plurality of triggers, which includes a trigger switch and a trigger network. The trigger switch, corresponding to one of the plurality of triggers, has a first end and a second end, in which the first end of the trigger switch is connected with a pad, and the second end of the trigger switch is connected with a voltage source having a first voltage value. Further, the trigger network, corresponding to a rest of the plurality of triggers, has at least one trigger sub-circuit electrically connected with the pad, in which the trigger network has an impedance value. When the trigger switch is triggered, due to an impedance value of the trigger network, the first voltage value will be detected at the pad.

Abstract: A sensing pixel array used in an image sensor includes sensing pixel units each including a photodiode, a row reset transistor, a buffer transistor, and a column control transistor at least. Photodiode converts light into a sensing signal. Row reset transistor is coupled to a reference reset signal and photodiode, and is controlled by a row reset signal. Buffer transistor is coupled to the output of photodiode to receive and buffer the sensing signal. Column control transistor is electrically connected to the control end or the output of the buffer transistor and is used as a switch which can be closed or open according to a column control signal to control whether to transfer charge of the reference reset signal to a capacitor when the row reset transistor becomes conductive.

Abstract: A sensing pixel array used in an image sensor includes sensing pixel units each including a photodiode, a row reset transistor, a buffer transistor, and a column control transistor at least. Photodiode converts light into a sensing signal. Row reset transistor is coupled to a reference reset signal and photodiode, and is controlled by a row reset signal. Buffer transistor is coupled to the output of photodiode to receive and buffer the sensing signal. Column control transistor is electrically connected to the control end or the output of the buffer transistor and is used as a switch which can be closed or open according to a column control signal to control whether to transfer charge of the reference reset signal to a capacitor when the row reset transistor becomes conductive.

Abstract: Methods of treating orthostatic hypotension are disclosed. The methods include administering to a subject in need thereof an effective amount of a beta 2 (?2) adrenoceptor antagonist, and in particular, the specific ?2 adrenoceptor antagonist, 3-(isopropylamino)-1-[(7-methyl-4-indanyl)oxy]butan-2-ol.

Abstract: A vessel sensing device with automatic amendment function includes an analog processing circuit, a signal generating circuit and a DC voltage detecting circuit. The analog processing circuit includes an optical sensing module. An optical sensor of the optical sensing module generates an analog signal with a skin characteristic signal and a vessel characteristic signal according to an optical reflecting signal. The skin characteristic signal and the vessel characteristic signal respectively correspond to a skin feature and a vessel feature of the user. The signal generating circuit is coupled to the analog processing circuit to transform the analog signal into a compensation signal. The DC voltage detecting circuit is coupled to the signal generating circuit and adapted to compensate the analog processing circuit according to the compensation signal, so as to decrease the skin characteristic signal within the analog signal.

Abstract: System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes. The system also includes a signal processor configured to receive the electrical signals from the signal detector, and apply a filter to the received electrical signals to generate filtered signals, the filter configured to attenuate at least signals having frequencies corresponding to heart muscle activity during a heartbeat. The signal processor is also configured to identify a skin nerve activity using the filtered signals, estimate a sympathetic nerve activity using the identified skin nerve activity, and further to generate a report indicative of the estimated sympathetic nerve activity. In some aspects, the system further includes a signal generator to deliver the electrical stimulation to the subject's skin.

Abstract: System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes. The system also includes a signal processor configured to receive the electrical signals from the signal detector, and apply a filter to the received electrical signals to generate filtered signals, the filter configured to attenuate at least signals having frequencies corresponding to heart muscle activity during a heartbeat. The signal processor is also configured to identify a skin nerve activity using the filtered signals, estimate a sympathetic nerve activity using the identified skin nerve activity, and further to generate a report indicative of the estimated sympathetic nerve activity. In some aspects, the system further includes a signal generator to deliver the electrical stimulation to the subject's skin.

Abstract: Systems and methods for controlling a ventricular rate during atrial fibrillation are provided. In some aspects, a method includes selecting a treatment protocol based on a determined condition of a subject, the treatment protocol comprising intermittent periods of electrical stimulation separated by periods of non-stimulation. The method also includes applying an electrical stimulation, according to the selected the treatment protocol, using an electrical source and at least one electrode positioned at locations associated with a vagal nerve of the subject to control a ventricular rate during atrial fibrillation.

Abstract: A method comprises receiving, in a computer, an input indicative of a drawing of at least a portion of at least one layer of a semiconductor device. The at least one portion of the at least one layer is compared to corresponding portions in corresponding layers of a plurality of previously defined devices stored in a non-transitory machine readable storage medium. Each layer of at least one of the plurality of previously defined devices for which the corresponding portion in the corresponding layer matches the at least one portion of the at least one layer of the semiconductor device is displayed on a display device.

Abstract: A method of determining a device type and device properties includes receiving an input file including information related to a device, and identifying at least one layer set within the input file. The method further includes identifying at least one feature present in layer set. The method further includes analyzing a relationship between the at least one feature formed by the first layer and at least one feature formed by the second layer to determine at least one layer set relationship. The method further includes comparing the layer set relationship with at least one template layer set relationship. The method further includes determining the device type of the device based on the comparison between the layer set relationship and the template layer set relationship. The method further includes determining the device properties of the device based on the layer set relationship, the device type or the at least one feature.