Abstract: Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRK1 A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder.

Abstract: The present disclosure provides a magnetic resonance imaging (MRI) device. The MRI device may include a main magnet configured to generate a main magnetic field. The main magnet may form an accommodation space configured to accommodate a target object. The main magnet may include at least one group of main field coils. A direction of the main magnetic field generated by the at least one group of main field coils may form a preset angle with an axial direction of the accommodation space. The at least one group of main field coils may include a first group of main field coils and a second group of main field coils that are arranged oppositely along a radial direction of the accommodation space. Each of the first group of main field coils and the second group of main field coils may bend towards each other.

Abstract: Disclosed is a medical treatment apparatus. The medical treatment apparatus includes a magnetic resonance imaging (MRI) device, configured for imaging of a specific region including a target object and generating a magnetic resonance image; a laser interstitial thermal therapy (LITT) device, including an LITT probe, the LITT probe being positioned close to the target object based on the magnetic resonance image, and being configured to treat the target object by emitting laser; and a temperature measurement element, the temperature measurement element and the LITT probe being integrated as an integrated probe, and the temperature measurement element being configured to obtain a temperature of the target object.

Abstract: Embodiments provide a battery, an electric device, and a method and a device for preparing battery cell, featuring a higher space utilization. The battery includes: a plurality of battery cells, where the plurality of battery cells are arranged in a first direction, a first region on an edge of a first surface of each of the plurality of battery cells is recessed to form a first recess, a first electrode terminal of each of the battery cells is protrusively provided on a second surface of the battery cell, the first surface and the second surface are perpendicular to the first direction, and the plurality of battery cells include a first battery cell and a second battery cell that are adjacent; and a first busbar configured to connect first electrode terminals of the adjacent first battery cell and second battery cell.

Abstract: A system for multi-modal multi-task processing includes a task representation component configured to determine a task representation element corresponding to a task representation framework that is used to define a content format for describing a to-be-processed task, and the task representation element including an element used to define task description information, an element used to define task input information, and an element used to define task output information; and based on the task representation element, acquire task description information, task input information, and task output information corresponding to each of to-be-processed tasks in different modalities; a data conversion component configured to determine an encoding sequence corresponding to each of the to-be-processed tasks; and a data processing component configured to process each of the to-be-processed tasks based on the encoding sequence corresponding to each of the to-be-processed tasks to obtain a task processing result correspon

Abstract: Disclosed is a medical treatment apparatus. The medical treatment apparatus includes a magnetic resonance imaging (MRI) device, configured for imaging of a specific region including a target object and generating a magnetic resonance image; a laser interstitial thermal therapy (LITT) device, including an LITT probe, the LITT probe being positioned close to the target object based on the magnetic resonance image, and being configured to treat the target object by emitting laser; and a temperature measurement element, the temperature measurement element and the LITT probe being integrated as an integrated probe, and the temperature measurement element being configured to obtain a temperature of the target object.

Abstract: A task processing method including associating and controlling, by a processing unit, a first resource to perform a task processing operation through N virtual resource identifiers in response to a task processing instruction. N is the number of data processing resources required for the task processing operation. The first resource includes n data processing resources, and n is an integer greater than or equal to 1, n<N. The method further includes associating, by the processing unit, a second resource with N-n virtual resource identifiers when the second resource switches from a second state to a first state. The second resource includes at least one data processing resource in a cluster other than the first resource. The method further includes controlling, by the processing unit, the first resource and the second resource to continue to perform the task processing operation through the N virtual resource identifiers.

Abstract: Provided are a battery, a power consumption device, a method for producing a battery, and a device. The battery includes: a plurality of battery cells arranged along a first direction and a thermal management component extending along the first direction and being connected to a first wall of each battery cell among the plurality of battery cells, the thermal management component including a pair of heat conducting plates that are oppositely arranged along a second direction and a flow passage located between the pair of heat conducting plates, the flow passage being configured to accommodate a fluid to adjust temperatures of the battery cell, and the second direction being vertical to the first wall, where in the second direction, a thickness D of the heat conducting plate and a size H of the flow passage satisfy: 0.01?D/H?25. Technical solutions of embodiments of the present application could enhance performance of batteries.

Abstract: Systems, apparatuses, and methods for the transit of a superconducting magnet are provided. The apparatuses may include a compressor configured to compress a cryogen after the cryogen cools a superconducting magnet in the transit of the superconducting magnet. The compressed cryogen may be used to cool the superconducting magnet. The apparatuses may also include a power supply device configured to provide power to the compressor and a thermal management system configured to in thermal communication with the compressor. The apparatuses may further include a container configured to accommodate at least one of the compressor, the thermal management system, and the power supply device.

Abstract: A pressure relief apparatus includes a pressure relief portion provided with a first surface and a second surface arranged opposite to each other in a thickness direction of the pressure relief portion, and at least one stage of depressed groove and an indented groove. The at least one stage of depressed groove and the indented groove are formed in the pressure relief portion in sequence in a direction from the first surface to the second surface. A groove bottom wall of the stage of depressed groove farthest away from the first surface among the at least one stage of depressed groove is provided with an opening area. The indented groove is formed along an edge of the opening area. The opening area is configured to be openable with the stage of indented groove farthest away from the first surface as a boundary.

Abstract: The present disclosure provides a momentum-matching and band-alignment van der Waals (vdW) infrared photodetector and a fabrication method thereof. The photodetector includes a substrate, a dielectric layer, a Bi2O2Se layer, a black phosphorus (BP) layer, a metal source and a metal drain. The fabrication method includes: transferring, in a wet manner, the Bi2O2Se layer grown on the mica substrate onto the substrate having the dielectric layer, transferring the mechanically exfoliated BP layer through a micro-region fixed-point transfer device onto the Bi2O2Se layer, and separately fabricating the metal source and the metal drain on the Bi2O2Se layer and the BP layer by processes such as electron beam exposure and electron beam evaporation, thereby forming the momentum-matching and band-alignment vdW infrared photodetector having a vertical structure.

Abstract: Provided are a battery, an electric apparatus, and a method and an apparatus for manufacturing battery, so as to enhance safety performance of the battery. The battery includes: a battery cell, where a first wall of the battery cell is provided with a pressure relief mechanism; a firefighting pipe configured to accommodate a firefighting medium and discharge the firefighting medium when the pressure relief mechanism is actuated; and a fixing member disposed between the first wall and the firefighting pipe. The firefighting pipe includes a first restraint member, and the fixing member includes a second restraint member, where the two restraint members fit with each other to restrict the firefighting pipe in a first direction and a second direction, the first direction is perpendicular to the first wall, and the second direction is parallel to the first wall and perpendicular to an extending direction of the firefighting pipe.

Abstract: The present embodiments relate to an improved mobile cooling box with an ice maker that is capable of freezing water and making ice, for example, ice cubes.

Abstract: Disclosed herein are embodiments of systems, methods, and products comprises an analytic server, which evaluates user data for premium financing status and dynamically renders graphical user interfaces. The server trains an artificial intelligence model based on historical user data. The artificial intelligence model comprises one or more data points with each data point representing one of a plurality of attributes and applies a logistic regression algorithm to identify a weight factor for each attribute. The server uses a dynamic algorithm to generate a score by combining the plurality of attributes based on the weight factors. The server receives responses regarding the scores that indicate the premium financing status of each case. The server retrains the artificial intelligence model to identify new weight factors based on negative responses data. The server automatically displays new scores calculated based on the new weight factors.

Abstract: The present disclosure relates to a cap assembly and a secondary battery. The cap assembly includes a cap plate provided with an electrode lead-out hole; an electrode terminal, covering the electrode lead-out hole and including a main body, wherein the main body is provided with a recess on a side wall; an isolating member including a receiving portion, wherein the main body is received in the receiving portion; and a protrusion, connected to an inner wall of the isolating member and extending towards an axis of the electrode lead-out hole, wherein the protrusion is received in the recess so as to prevent the main body from rotating relative to the isolating member. The cap assembly according to the embodiments of the present application can improve an overcurrent capacity and stability of the electrode terminal.

Abstract: A fully-automatic photography method for a fundus image includes moving a lens of the fundus camera to align with the pupil, controlling the lens to approach the eyeball and capturing an image, the image being formed by an illuminating beam reflected by the cornea, determining a working distance by using the image, adjusting the focal length, capturing a fundus image, and determining a photography focal length by using the fundus image, and photographing a fundus image by using the photography focal length on the working distance.

Abstract: The present invention discloses a negative pressure wave monitoring based leak detection method of a multipath pipeline network, including: analyzing a propagation process of a negative pressure wave in a single straight pipeline to obtain a calculated result of a sound velocity in a thin-walled pipe marking the pressure sensors at known disposing positions on a pipeline network map; linearly interpolating position coordinates of key nodes in the pipeline network to extend pipeline network information; resolving the time that a negative pressure wave signal generated by a leak propagates to each disposed RTUs to form a data column; and simulating a leak situation, detecting a pipeline pressure waveform by using the RTUs in a current network, and determining a point corresponding to the data column closest to a measured propagation time delay in the time delay standard library as a leak point, and outputting the position of the leak point.

Abstract: Embodiments of the present application provide a battery. The battery includes: a battery cell comprising a pressure relief mechanism, the pressure relief mechanism being arranged in a first wall of the battery cell and the pressure relief mechanism being configured, when an internal pressure or temperature of the battery cell reaches a threshold, to be actuated to release the internal pressure; and a thermal management component for containing a fluid to adjust the temperature of the battery cell; wherein a first surface of the thermal management component is attached to the first wall, and the thermal management component is configured to be capable of being damaged when the pressure relief mechanism is actuated, so that the fluid is discharged from inside of the thermal management component. According to the technical solutions of the embodiments of the present application, the safety of the battery can be enhanced.

Abstract: An embodiment may involve: transmitting, by a non-production computational instance and to a central computational system, a configuration for a service provided by the central computational system, wherein the non-production computational instance is arranged to test the configuration; appending, to the configuration at the non-production computational instance, a synchronization identifier to indicate that the configuration has been synchronized with the central computational system; receiving, by a production computational instance and from the non-production computational instance, a copy of the configuration; reading, by the production computational instance, the synchronization identifier from the copy of the configuration; determining that the synchronization identifier is not reflected as part of a synchronization history maintained at the production computational instance; and, in response to determining that the synchronization identifier is not reflected in the synchronization history, transmitting

Abstract: This application discloses a battery pack and a vehicle, including: a case assembly, including an accommodating cavity; a battery module, disposed in the accommodating cavity, wherein the battery module includes a battery cell assembly, where the battery cell assembly includes an output current collector and a plurality of battery cells arranged side by side along a first direction of the battery pack, and the output current collector is configured to output electric energy of the battery cell assembly; and an end plate assembly, including a body plate and a protective cover, where the body plate is located at an end of the battery cell assembly along the first direction, the protective cover is rotatably connected to the body plate, and at least a part of the output current collector is located between the body plate and the protective cover.