Patents by Inventor Peng Yi
Peng Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260240839Abstract: The present invention provides a pharmaceutical composition of tetramethylpyrazine nitrone for injection and a method of manufacture thereof, wherein the pharmaceutical composition has good stability. The pharmaceutical composition of tetramethylpyrazine nitrone for injection is a freeze-dried powder injection, the characteristics thereof on appearance, acidity, moisture content, related substances, insoluble particles, content detection, sterility, and visible foreign objects are all in compliance with relevant regulations. The method of manufacture of the pharmaceutical composition is simple, and the prepared tetramethylpyrazine nitrone freeze-dried powder injection has good formability. The freeze-drying process of the present invention has good stability and short freeze-drying time, and the process can be performed for effectively saving energy and labor, and is suitable for industrial production.Type: ApplicationFiled: February 24, 2023Publication date: August 20, 2026Applicant: GUANGZHOU MAGPIE PHARMACEUTICALS CO., LTD.Inventors: Yuqiang WANG, Yewei SUN, Gaoxiao ZHANG, Zaijun ZHANG, Peng YI
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Publication number: 20260242330Abstract: The present invention provides the use of an amantadine mononitrate compound in the manufacture of a medicament for the prevention and treatment of hypertension. The amantadine mononitrate compound can be administered to reduce the systolic and/or diastolic pressure of subjects. The amantadine mononitrate compound has a long half-life and long drug action time in subjects and can reduce the number of administration times and improve patient compliance as compared to existing hypertensive drugs. The medicament of the amantadine mononitrate compound of the present invention has no adverse reactions of orthostatic hypotension, and thus has improved the safety of the drug use.Type: ApplicationFiled: February 24, 2023Publication date: August 20, 2026Applicant: GUANGZHOU MAGPIE PHARMACEUTICALS CO., LTD.Inventors: Yuqiang WANG, Yewei SUN, Gaoxiao ZHANG, Zaijun ZHANG, Peng YI
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Publication number: 20260137501Abstract: An intraluminal prosthesis for treating portal hypertension. The intraluminal prosthesis includes a stent architecture having a first section including a plurality of unconnected annular members, a second section coupled to a first end annular member of the first section, the second section formed of woven struts, and a tubular graft covering the first section. The plurality of unconnected annular members can each be formed of a plurality of diamond-shaped cells. A terminal portion of the second section can include a number of tantalum keys. The tubular graft can be formed of high-density polyethylene or expanded polytetrafluoroethylene.Type: ApplicationFiled: January 12, 2026Publication date: May 21, 2026Inventors: Peng Yi, Zhixiu He, Hongliang Ma
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Publication number: 20260125651Abstract: Compositions of genetically modified beta-like cells are encompassed. Also encompassed are methods of treatment of type 1 diabetes using these compositions or compositions that inhibit the function of the identified genes.Type: ApplicationFiled: January 7, 2026Publication date: May 7, 2026Applicant: Joslin Diabetes CenterInventors: Stephan Kissler, Peng Yi
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Patent number: 12545895Abstract: Compositions of genetically modified beta-like cells are encompassed. Also encompassed are methods of treatment of type 1 diabetes using these compositions or compositions that inhibit the function of the identified genes.Type: GrantFiled: June 6, 2023Date of Patent: February 10, 2026Assignee: Joslin Diabetes CenterInventors: Stephan Kissler, Peng Yi
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Patent number: 12521225Abstract: An intraluminal prosthesis (100) and methods thereof for treating at least portal hypertension. The intraluminal prosthesis (100) includes a mixed frame of a main frame (110) and a terminal frame (120), as well as a tubular graft (130) over at least the main frame (110). The main frame (110) includes a plurality of annular members (112). Each annular member (112) includes a plurality of diamond-shaped cells (114). The terminal frame (120) includes woven struts (122). The terminal frame (120) includes a coupled end (124) coupled to at least one of a first-end annular member (112a) or a second-end annular member (112b) respectively at a first end (110a) or a second end (110b) of the main frame (110). The tubular graft (130) extends from the first-end annular member (112a) to the second-end annular member (112b). The intraluminal prosthesis (100) includes an insertion state for inserting the intraluminal prosthesis (100) and an expanded state for use of the intraluminal prosthesis (100) is in use.Type: GrantFiled: January 31, 2019Date of Patent: January 13, 2026Assignee: Becton, Dickinson and CompanyInventors: Peng Yi, Zhixiu He, Hongliang Ma
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Patent number: 12396753Abstract: A needle-tract assistants (100, 200) for establishing a needle tract of a predetermined length, including a needle thruster (110, 210) and a needle-in-catheter assembly (130, 230) removably loaded in the needle thruster (110, 210). The needle thruster (110, 210) can include a cradle (112, 212), a carriage(114, 214) within the cradle (112, 212), and a plunger (116, 216) coupled to the carriages (114, 214). The carriages (114, 214) can be configured to move between a proximal-end portion and a distal-end portion of the cradle(112, 212). The plungers (116, 216) can be configured to move the carriages (114, 214) within the cradle(112, 212). The plungers (116, 216) can also be configured to allow a user to set the predetermined length of the needle tract before establishing the needle tract.Type: GrantFiled: May 24, 2019Date of Patent: August 26, 2025Assignee: Becton, Dickinson and CompanyInventors: Peng Yi, Xiaowen Sun, Zhixiu He, Neville Chia
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Patent number: 12393633Abstract: The present specification relates to the field of digital information, and in particular, to a flow graph calculation and storage method and system. A flow graph includes nodes and edges, and the method includes one or more rounds of processing respectively corresponding to one or more time periods. A round of processing includes: obtaining a graph data segment of a current subgraph based on newly added flow information in a current time period and storing the graph data segment, so as to implement distributed storage of the current subgraph in collaboration with another calculation unit; and for a node in the graph data segment of the current subgraph, obtaining a flow message of data corresponding to an ingress edge of the node from a source node on the ingress edge and storing the flow message, where the flow message includes a source link of the data.Type: GrantFiled: September 5, 2023Date of Patent: August 19, 2025Assignee: Alipay (Hangzhou) Information Technology Co., Ltd.Inventors: Kun Tang, Peng Yi
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Patent number: 12381822Abstract: Disclosed are a data flow table for high-speed large-scale concurrent data flows, method and apparatus for processing the data flow table, and a storage medium. The method includes: acquiring, according to a data flow identifier of a data flow to be inserted, addresses of candidate buckets in a fingerprint table and a data flow fingerprint; detecting whether there is an idle unit in the candidate buckets in the fingerprint table, if there is an idle unit, selecting the candidate bucket having the idle unit as target bucket; and sequentially searching for the idle unit from bottom unit to top unit of the target bucket, and when the idle unit is found in the target bucket, writing data flow fingerprint of said data flow into the found idle unit, and writing data flow record of said data flow into a recording bucket corresponding to the candidate bucket.Type: GrantFiled: October 28, 2020Date of Patent: August 5, 2025Assignee: PURPLE MOUNTAIN LABORATORIESInventors: Jin Zhang, Dun Yang, Xuewu Pei, Yiming Jiang, Youjun Bu, Hailong Ma, Peng Yi
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Patent number: 12377095Abstract: The present invention relates to the use of ligustrazine nitrone derivatives and pharmaceutical composition thereof for the treatment and prevention of diseases of diabetic complications, which include renal anemia. The ligustrazine nitrone derivatives have the structure of the general formula (I). Experimental results indicated that the ligustrazine nitrone derivatives can significantly increase the levels of serum iron and erythropoietin in STZ induced SD rats and spontaneously hypertensive rats, and can be used for treating and preventing renal anemia caused by decrease in renal EPO production and/or concomitant iron deficiency. Therefore, the ligustrazine nitrone derivatives can be made into various dosage forms with a drug carrier. The derivatives can be prepared into various dose forms together with drug carriers.Type: GrantFiled: November 3, 2021Date of Patent: August 5, 2025Inventors: Yuqiang Wang, Yewei Sun, Lipeng Xu, Mei Jing, Zaijun Zhang, Gaoxiao Zhang, Pei Yu, Peng Yi
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Publication number: 20250181935Abstract: According to an example, each piece of first-type service data is modeled as a vertex in a graph; each piece of second-type service data is modeled as an edge in the graph; a structural feature value corresponding to each vertex is obtained based on a predetermined structural feature corresponding to the first-type service data; a structural feature value corresponding to each edge is obtained based on a predetermined structural feature corresponding to the second-type service data, where the structural feature is a feature commonly used in at least two application scenarios; and modeling is performed by using each vertex, the structural feature value of the vertex, each edge, and the structural feature value of the edge, to obtain a structural graph, where each vertex and each edge in the structural graph are mounted with corresponding structural feature values.Type: ApplicationFiled: January 10, 2023Publication date: June 5, 2025Inventors: Kun TANG, Peng YI
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Publication number: 20250144152Abstract: This disclosure relates to methods of inducing insulin production from pancreatic duct cells in response to glucose or transdifferentiating pancreatic duct cells into insulin-producing beta-like cells by administering an agent that inhibits aldehyde dehydrogenase family 3 member B2 (ALDH3B2) protein or an agent that inhibits the expression of ALDH3B2 gene. This disclosure also relates to methods of treatment of diabetes by administering an agent that inhibits ALDH3B2 protein or an agent that inhibits the expression of ALDH3B2 gene.Type: ApplicationFiled: December 12, 2024Publication date: May 8, 2025Applicant: Joslin Diabetes CenterInventor: Peng Yi
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Patent number: 12261692Abstract: Provided are a data processing system and method based on dynamic redundancy heterogeneous encoding, and a device. The method comprises: respectively performing error correction encoding on information to be processed and a processing rule, so as to form encoded information to be processed and an encoded processing rule; processing, by using the encoded processing rule, the encoded information to be processed, so as to obtain response data; and then performing error correction decoding on N pieces of response data, so as to obtain processing result information of the information to be processed.Type: GrantFiled: June 7, 2021Date of Patent: March 25, 2025Assignees: CHINA NATIONAL DIGITAL SWITCHING SYSTEM ENGINEERING & TECHNOLOGICAL R&D CENTER, ZHUHAI COMLEADER INFORMATION SCIENCE & TECHNOLOGY CORP., LTD.Inventors: Lei He, Jiangxing Wu, Quan Ren, Peng Yi, Xiang Chen, Jing Yu, Kun Zhou, Yiwei Guo, Zhifeng Feng
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Publication number: 20250053177Abstract: A robot control method, including: determining a target operation map according to target position information of a current operation of a robot; determining, based on a pre-established map connection relationship, a transfer position that the robot moves to; controlling the robot to move to the transfer position and switching maps, until the robot moves to the target operation map; and controlling the robot to move to an operation destination according to map information of the target operation map and the target position information.Type: ApplicationFiled: April 29, 2024Publication date: February 13, 2025Inventors: Zihan SHANG, Kun Du, Kai Liu, Linfeng Wen, Song Ding, Peng Yi, Zhongxing Bai
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Publication number: 20250055166Abstract: A battery and an electronic product, where the battery includes battery cell, a housing, a terminal post base and a first insulator, where the housing is provided with an accommodating cavity, and the battery cell is arranged in the accommodating cavity; the terminal post base includes a body and a terminal post, a terminal post hole is arranged on a side wall of the housing, the first insulator is arranged between the housing and the body, and a first positioning hole opposite to the terminal post hole is arranged on the first insulator, and the terminal post sequentially passes through the first positioning hole and the terminal post hole, and the terminal post is connected to a tab of the battery cell; the first insulator is further provided with a third limiting part, and an outer side wall of the housing is provided with a fourth limiting part.Type: ApplicationFiled: October 28, 2024Publication date: February 13, 2025Inventors: Zhida WEI, Jichun XIE, Hui ZHANG, Chengbei LI, Peng YI, Yang XI
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Patent number: 12131928Abstract: A dynamic dispatching method for semiconductor manufacturing system relates to a dynamic dispatching rule based on self-organization for dispatching in a semiconductor manufacturing system, including S1: setting roles and parameters of self-organization units, and defining key nodes in a production environment; S2: constructing a negotiation mechanism between the self-organization units, and designing a decision-making and dispatching subject ESOU; S3: according to a decision instruction of the ESOU, designing a LSOU allocation dispatching unit for distinguishing single-batch processing and multi-batch processing; and S4: designing a dispatching mechanism based on the self-organization units to implement dynamic semiconductor dispatching. The dynamic dispatching method includes three aspects: role definitions of self-organization units, a negotiation mechanism between the self-organization units and a decision-making method thereof.Type: GrantFiled: March 31, 2022Date of Patent: October 29, 2024Assignee: TONG JI UNIVERSITYInventors: Li Li, Kuo-Yi Lin, Jie Chen, Yiguang Hong, Qingyun Yu, Peng Yi, Jinlong Lei, Xiouxian Li, Min Meng
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Publication number: 20240240152Abstract: Compositions of genetically modified beta-like cells are encompassed. Also encompassed are methods of treatment of type 1 diabetes using these compositions or compositions that inhibit the function of the identified genes.Type: ApplicationFiled: June 6, 2023Publication date: July 18, 2024Applicant: Joslin Diabetes CenterInventors: Stephan Kissler, Peng Yi
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Publication number: 20240121027Abstract: Provided are a data processing system and method based on dynamic redundancy heterogeneous encoding, and a device. The method comprises: respectively performing error correction encoding on information to be processed and a processing rule, so as to form encoded information to be processed and an encoded processing rule; processing, by using the encoded processing rule, the encoded information to be processed, so as to obtain response data; and then performing error correction decoding on N pieces of response data, so as to obtain processing result information of the information to be processed.Type: ApplicationFiled: June 7, 2021Publication date: April 11, 2024Inventors: Lei HE, Jiangxing WU, Quan REN, Peng YI, Xiang CHEN, Jing YU, Kun ZHOU, Yiwei GUO, Zhifeng FENG
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Patent number: 11917523Abstract: A polymorphic network control system and a polymorphic network control system method supporting terminal mobile access. A network architecture is redesigned based on the idea of separation of an identifier from a locator. In this network mode, the three-layer protocol is no longer a traditional IP message, but a message carrying a locator and an identifier. The polymorphic SDN network controller is responsible for forwarding the data packet to a destination corresponding to a destination locator. When the network location of a mobile device is changed, the transmission connection established based on the identifier will suspend communication due to the disconnection of the physical link. When the mobile device is re-accessed and a new forwarding path is established, the transmission connection can recover communication.Type: GrantFiled: May 30, 2023Date of Patent: February 27, 2024Assignees: ZHEJIANG LAB, INFORMATION ENGINEERING UNIVERSITYInventors: Zhongxia Pan, Peng Yi, Le Tian, Tao Zou, Juan Shen
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Patent number: 11903923Abstract: The present invention provides uses of an andrographolide derivative in preparation of a medicament for preventing and treating inflammatory bowel disease. The andrographolide derivative AL-1 has the mechanisms, for the treatment of ulcerative colitis, of scavenging of free radicals, inhibition of NF-?B signaling pathway activation and COX-2 expression, activation of PPAR-? expression, and thus can prevent the transcription and expression of inflammatory-related genes to improve the conditions of inflammation. AL-1 can be used as a medicine for the treatment of inflammatory bowel disease and can be formulated to various dosage forms with a pharmaceutically acceptable carrier.Type: GrantFiled: July 4, 2016Date of Patent: February 20, 2024Inventors: Yuqiang Wang, Lipeng Xu, Pei Yu, Yewei Sun, Zaijun Zhang, Gaoxiao Zhang, Peng Yi