Abstract: The present invention relates to bicyclic heterocycles, and pharmaceutical compositions of the same, that are inhibitors of the FGFR enzyme and are useful in the treatment of FGFR-associated diseases such as cancer.

Abstract: One method interpolates simulated seismic data of a coarse spatial sampling to a finer spatial sampling using a neural network. The neural network is previously trained using a set of simulated seismic data with the finer spatial sampling and a subset thereof with the coarse spatial sampling. The data is simulated using an image of the explored underground formation generated using real seismic data. The seismic dataset resulting from simulation and interpolation is used for denoising the seismic data acquired over the underground formation. Another method demigrates seismic data at a sparse density and then increases density by interpolating traces using a neural network.

Abstract: The disclosure provides a method, a device and a computer readable medium for determining the penguin population relating to the technical field of image processing. The method of one embodiment of the disclosure comprises the following steps: firstly acquiring the penguin habitat image detected by the unmanned airborne sensor; and acquiring an interest region with penguins distributing, and a gray value of the interest region from the penguin habitat image; then for any one of gray value: determining a penguin state according to the gray value; finally determining the penguin population according to the penguin state.

Abstract: Problem Diagnosis Automation System (PDAS) automates the diagnosis of repetitive problems and the enforcement of preventive measures across a network. Automation assets across the network include Network Intent (NI) inside the no-code platform. A Network Intent Cluster (NIC) clones a NI across the network to create a group of NIs (member NIs) with the same design or logic. A subset of Member NIs can be executed according to user-defined conditions based on the member device, the member NI tags, or signature variables. A Triggered Automation Framework (TAF) matches the incoming API calls from a 3rd party system to current incidents and installs the automation (e.g., NI/NIC) to be triggered for each call. It may include: Integrated IT System defining the scope and data of the incoming API calls; Incident Type to match a call to an Incident; and Triggered Diagnosis to define what and how the NIC/NI is executed.

Abstract: A grouting double-locking pressure real-time sensing system includes: a positioning structure fixed to a ground; wherein an expandable positioning structure passes through the positioning structure, and an input end of the expandable positioning structure is connected to the grouting structure; the pressure real-time monitoring component is connected to the expandable positioning structure; the expandable positioning structure comprises a hollow conduit, an expandable assembly, an upper positioning member, and a lower positioning member; wherein the upper positioning member and the lower positioning member are respectively connected to two ends of the expandable assembly; the hollow conduit passes through the upper positioning member and the lower positioning member, and is threaded to the the lower positioning member; the upper positioning member is fixed to the positioning structure; when rotating the hollow conduit, the lower positioning member moves up and down, so as to expand or contract the expandable

Abstract: The present disclosure provides an alert task processing method, a terminal, and a computer-readable storage medium. The alert task processing method includes: receiving a first input of a first operator; performing a screen capturing operation, outputting a screenshot, and obtaining first biometric feature information of the first operator in response to the first input; and performing a target alert task based on the screenshot and the first biometric feature information.

Abstract: Various embodiments relate to a detector circuit, including: a voltage source configured to produce a first voltage on a first output, a second voltage on a second output, and third voltage on a third output, wherein the first voltage is greater than the second voltage and the second voltage is greater than the third voltage; a first switch connected to the second output; a sampling capacitor connected to the switch, wherein the sampling capacitor is charged by the voltage source when the switch is closed; a first comparator with one input connected to the first output and a second input connected to the sampling capacitor; a second comparator with one input connected to the third output and a second input connected to the sampling capacitor; a multiplexer with a plurality of inputs configured to be connected to a plurality of terminals of an external circuit and an output connected to the sampling capacitor, the first input of the first comparator, and the first input of the second comparator; and a controll

Abstract: A method of manufacturing a glass ribbon can comprise flowing a glass-forming ribbon along a travel path. The glass-forming ribbon can comprise a first major surface and a second major surface opposite the first major surface. A thickness can be defined between the first major surface and the second major surface. The method can comprise heating the first major surface of the glass-forming ribbon at a target location of the travel path while the glass-forming ribbon is travelling along the travel path. The heating can increase a temperature of the glass-forming ribbon at the target location to a heating depth of about 250 micrometers or less from the first major surface. The method can comprise cooling the glass-forming ribbon into the glass ribbon. Prior to the heating, the glass-forming ribbon at the target location can comprise an average viscosity in a range from about 1,000 Pascal-seconds to about 1011 Pascal-seconds.

Abstract: The present invention relates to a reagent for exploiting natural gas hydrates, which includes a regent A and a regent B. The reagent A is PEG400-polyurethane prepolymer; the reagent B includes PEG400 and an initiator; and a volume ratio of the PEG400-polyurethane prepolymer, the PEG400 and the initiator is (1-3000):(1-1000):(1-2000). The reagent of the present invention has excellent performance and high stability, and can effectively “replace” the “water” of the natural gas hydrate; and moreover, the reaction is exothermic reaction to effectively increase the reaction rate, which reduces the energy loss on the one hand, and reduces the blockage of a gas passage caused by the secondary generation of the natural gas hydrates in a low-temperature high-pressure pipeline during transferring on the other hand.

Abstract: Provided herein are methods and compositions related to treating and preventing an age-related disease and inhibiting cell death using thymosin proteins.

Abstract: A quantum chip and a quantum computer are disclosed to resolve problems such as high difficulty in preparing the quantum chip and a low yield rate. The quantum chip provided in the present disclosure includes a substrate, M subchips, a coupling structure, and a cavity mode suppression structure. Each subchip includes N quantum bits, and the M subchips are spaced apart on a surface of the substrate. The coupling structure is configured to implement an interconnection between the M subchips. The cavity mode suppression structure is disposed on an edge of each subchip and/or in a gap between the M subchips, and is configured to increase a cavity mode frequency of the quantum chip. In the quantum chip provided in the present disclosure, the quantum chip includes the M subchips, so that preparation difficulty is effectively reduced and a preparation yield rate is improved.

Abstract: The present disclosure discloses a method for on-line measurement of the polymer melt temperature, comprising: on-line measurement of ultrasonic sound velocity c of melt in an injection molding process, on-line measurement of melt pressure P in the injection molding process, and obtaining melt temperature T in the injection molding process by formula (1). The present disclosure also discloses an apparatus for on-line measurement of the polymer melt temperature. The method and the apparatus provided in the present disclosure may enable on-line and in-situ characterization of the melt density and further enable on-line quantitative measurement of the melt quality. Compared with infrared measurement methods, the method provided herein is significantly reduced in cost, which is of great significance to theoretical researches of crystallization process and shear heating.

Abstract: The disclosure discloses a solid fluidization tubular separator for marine natural gas hydrate, which includes a first separator and a second separator, wherein the first separator includes the first separation sleeve, the power liquid pipe, the swirl baffle, the recovery mechanism and the sand discharge mechanism. After the hydrate is sucked into the first separation sleeve to generate a circumferential velocity, so that the mud and sand with high density are separated to the pipe wall of the first separation sleeve, and the mud and sand separated to the pipe wall are settled down from the gap between the swirl baffle and the pipe wall along the pipe wall. The hydrate swirl flows into the recovery mechanism, and then leaves the first separation sleeve and enters the second separator, so as to realize the separation of mud and sand and natural gas hydrate.

Abstract: The application provides a method for growing multiple layers of source drain epitaxial silicon in an FDSOI process, forming a buried oxide layer on the substrate, and then forming an SOI layer on the buried oxide layer; forming a gate on the SOI layer, wherein a source drain region is provided on two sides of the gate; forming an undoped epitaxial layer on the SOI layer of the source drain region; forming a first doped epitaxial layer on the undoped epitaxial layer; forming a second doped epitaxial layer on the first doped epitaxial layer; and cleaning the substrate with deionized water. In the present application, the epitaxial silicon is changed from a single layer structure to a multilayer structure, wherein undoped epitaxial silicon can effectively prevent ion diffusion, and middle-highly doped epitaxial silicon and highly doped epitaxial silicon can significantly reduce source drain resistance and improve device performance.

Abstract: A feces color-based remote sensing estimation method and apparatus for Antarctic bird population size is disclosed, which comprises: determining a reflectance value range of a mixture of new feces and old feces in a remote sensing image; determining a sample mixture area where the mixture is located, based on the reflectance value range of the mixture in the remote sensing image; classifying the sample mixture area into a plurality of grade areas and determining an area of each grade area based on an obtained reflectance value of the sample mixture area; and generating a one-to-one correspondence between a density of birds of each grade area in the sample mixture area and the each grade area, based on the area of the each grade area and an obtained number of birds in the each grade area.

Abstract: An integrated comprehensive adjustment method for a pulverized coal boiler based on high-temperature corrosion prevention and control of water wall is provided. The method includes: during shutdown period of the boiler, mounting reducing atmosphere sampling pipe on a water-cooled wall region; carrying out a diagnostic test on the boiler; carrying out an optimization and adjustment test of a boiler pulverizing system; carrying out a single-factor adjustment test of boiler-related parameters; determining degrees of influence of different parameters on water wall reducing atmosphere, thermal efficiency of the boiler and NOx concentration at a denitration inlet; carrying out an optimization test of ammonia spraying of a denitration system; carrying out a maximum safe denitration efficiency test; and finding a balance point among the water wall reducing atmosphere, the thermal efficiency of the boiler and the NOx concentration at the denitration inlet.

Abstract: The present invention provides an efficient ultrasonic phased array phase shift migration imaging method for the defect in a multi-layer structure, including the following steps: (1) transforming full matrix capture data of a multi-layer structure to a frequency-wavenumber domain by means of three-dimensional fast Fourier transform; (2) for any non-traversed layer in the multi-layer structure, extrapolating a surface wave field of the multi-layer structure to an upper interface of the non-traversed layer, to obtain wave field information of the non-traversed layer; (3) according to the obtained wave field information, performing focus imaging on the non-traversed layer in the frequency-wavenumber domain; and (4) repeating the steps (2) and (3), until all layers are traversed, to obtain an imaging result of the multi-layer structure.

Abstract: An electronic device is described. The electronic device may include a housing, a rotatable crown, and a self-mixing interferometry (SMI) sensor positioned within the housing. The rotatable crown may include an array of retroreflective surface features that reflect incident light back to a light source. Each retroreflective surface feature of the array of retroreflective surface features may be formed as a corner-cube with three perpendicular faces. The SMI sensor or associated processing electronics may compare originally emitted light with reflected light to identify a movement or distance of the rotatable crown with respect to the SMI sensor.

Abstract: The present application discloses a pipeline radar and television inspection robot which includes a robot body, a directional drilling lifting device, a directional drilling rotary device, a directional drilling swing device, a radar, cameras and a driving apparatus; wherein the directional drilling lifting device is on a front part of the robot body; the directional drilling rotary device is on the directional drilling lifting device; the directional drilling swing device is on the directional drilling rotary device; the radar and the cameras are on the directional drilling swing device; the driving apparatus are on a bottom of the robot body. The directional drilling lifting device, the radar and the cameras are plugged in the robot body. The robot body electrically connects to cables which electrically connect to a control system. The cameras and the radar are able to be adjusted and the components are connected as modules.

Abstract: A function resource configuration method includes receiving, by a wearable device, a distribution request sent by a first terminal, where the distribution request is used to request the wearable device to distribute a first function resource of the wearable device to the first terminal, and where the first function resource is already occupied by a second terminal. The wearable device determines, based on the distribution request, whether to allow the first terminal to use the first function resource. If the wearable device allows the first terminal to use the first function resource, the wearable device sends a notification message to the first terminal that instructs the first terminal to use the first function resource.