Abstract: The present invention relates to nanoparticles for the targeted delivery of antigen to liver cells, in particular, liver sinusoidal endothelial cells (LSEC) and/or Kupffer cells, and for the in vivo generation of regulatory T cells, notably CD4+CD25+FOXP3+ regulatory T cells (Treg). The invention provides pharmaceutical compositions and methods for the prevention and treatment of autoimmune diseases, allergies or other chronic inflammatory conditions, and for generation of regulatory T cells. The nanoparticles used in the invention comprise a) a micelle comprising an amphiphilic polymer rendering the nanoparticle water-soluble, and b) a peptide comprising at least one T cell epitope associated with the outside of the micelle. The micelle may or may not comprise a solid hydrophobic core.

Abstract: The present invention relates to a method for producing a bonded article by press-moulding and carbonating a granular, carbonatable material. The granular material is applied in a mould, is press-moulded therein under a compaction pressure of at least 25 MPa, and is carbonated during said press-moulding step by means of a gas which contains at least 1 vol. % of carbon dioxide. By carbonating the material when press-moulding it, high compressive strengths can be achieved in a short period of time.

Abstract: The present invention relates to method for recycling alkaline waste water from a stainless steel slag treatment process wherein stainless steel slag is brought into contact with water thereby producing said waste water, which waste water contains heavy metals, including at least chromium, and has a pH of at least 12. The waste water is recycled by using it for treating an alkaline granular carbonatable material, which contains aluminium metal, in order to oxidise the aluminium metal contained therein. This material is in particular municipal waste incinerator bottom ash which can, after the treatment of the present invention, safely be used as fine or coarse aggregate in bonded applications such as concrete, mortar and asphalt. During the treatment with the alkaline waste water, hydrogen gas is produced which is captured and used to produce energy by means of a cogeneration device.

Abstract: A method of producing a mainly carbonate bonded article includes a step of providing an alkaline granular material having one or more alkaline earth metal silicate phases. The method includes a step of compacting the granular material to obtain a compact of the granular material. The porosity of the compact is smaller than or equal to 37% by volume. The intrinsic permeability of the compact is at least 1·10?12 cm2. The method also includes a reacting step arranged to form at least 5% by weight of carbonates (CO32?), by reacting the granular material with carbon dioxide in the presence of water, thus transforming the compact into the article. In the reacting step, the compact, being unsaturated with moisture at the beginning of the reacting step, is brought in an atmosphere having carbon dioxide. The atmosphere is at a temperature of at least 70° C. and at a pressure of at least 0.5 MPa. The pressure is also higher than the saturated vapor pressure of water at the temperature.

Abstract: The present invention relates to a method and a system for on-site and full-scale testing of wind turbine plants. In particular, the present invention relates to a method and a system applying resonance circuits tuned with the fundamental frequency, or harmonics thereof, of a power supply grid connected to a wind turbine plant to be tested. The wind turbine plant to be tested may remain connected to the power supply grid during on-site and full-scale testing.

Abstract: The present invention relates to the field of in vivo determination of enzyme activity. It also allows visualization of organisms, organs, tissues and cells. In particular, the present invention provides a method of in vivo visualization and a composition suitable for in vivo determination and/or visualization of enzyme activity by methods such as Magnetic Resonance Imaging, also called Magnetic Resonance Tomography (MRI or MRT), or Magnetic Particle Imaging (MPI). In particular, the activity of the enzyme lipoprotein lipase affects the signals received and allows conclusions on the lipid metabolism of an organism, an organ system, an organ, a tissue and a cell of interest, This method can be employed, e.g., for diagnosis of cardiac disorders, of tumor prognosis and of disorders of the lipid metabolism. The composition used comprises superparamagnetic iron oxide nanocrystals (SPIO) incorporated in the core of lipid micelles designated nanosomes.

Abstract: A segmented drain system comprises a drain body, operable to mate with a drain fitting installed in a bath or shower area, and a bonding flange body, adjustable relative to the drain body. An integrated bonding flange extends from the bonding flange body, the integrated bonding flange being operable to be sealably attached to a bondable waterproof membrane to provide a substantially water-tight seal between the membrane and the bonding flange body. A seal is oriented between the integrated bonding flange body and the drain body, the seal being operable to provide a slidable, substantially water-tight interface between the integrated bonding flange body and the drain body.

Abstract: A wind power plant, a wind power plant controller and a method of controlling a wind power plant are provided. The method includes a) preparing a telegram comprising wind turbine controlling data for one of the plurality of wind turbines of the wind power plant; b) sending the telegram to the wind turbine upon completion of the telegram; and c) successively repeating steps a) and b) for each of the remaining wind turbines. An initial response time of the wind power plant is shortened; thus, initial response time requirements of the wind power plant specified by grid codes may be fulfilled more easily.

Abstract: The present invention relates to a method for controlling a voltage level of a power supply grid operationally connected to a source of electrical power, the method comprising the steps of determining a short circuit impedance of the power supply grid at a point of common coupling, calculating, using the determined short circuit impedance, a gain value of the power supply grid, and controlling the grid voltage level in accordance with the calculated gain value by applying said gain value as a gain parameter in a voltage controller. The method according to the present invention may be implemented as a method for configuring a voltage controller once and for all, or it may be implemented as a method for adaptively adjusting a gain of a voltage controller.

Abstract: A visualization development system is provided. The system includes a visualization tool to develop one or more visualizations and a grammar engine that operates with the visualization tool to automatically detect visualization problems during the development of the visualizations.

Abstract: The invention relates to a method of calculating an electrical output of a wind power plant comprising a plurality of wind turbines. Instead of calculating the electrical output of the wind power plant as a simple aggregation of the outputs of each wind turbine, the method takes into account parameters which may vary stochastically throughout the wind power plant, e.g. pitch angle, stiffness in drive train, different possible production with regard to reactive and active effect, mechanical component properties as well as variability in relation to communication times between a power plant controller and the individual wind turbines. The method proposes to make adjustment to a simple aggregation calculation method based on analysis of such stochastic varying parameters.

Abstract: A shower drain adapter system configured to allow use of a bondable waterproof membrane with a shower pan drain system comprises a drain body and an integrated bonding flange extending upwardly from the drain body. The integrated bonding flange is operable to be sealably attached to a bondable waterproof membrane to provide a substantially waterproof seal between the membrane and the adapter. A lower mating flange is separable from the drain body, the lower mating flange operable to mate with a component of a shower pan drain system installable on a waste pipe. The lower mating flange includes a substantially rigid frame; and a pliable gasket disposed at least partially about the frame, the pliable gasket having an inner diameter sized to correspond to an outer diameter of a portion of the drain body.

Abstract: A visualization input system is provided. The system includes a visualization component that receives input gestures from a user (or users) and translates the gestures into one or more data manipulation commands. A distribution component receives the data manipulation commands and propagates data modifications across one or more databases in view of the commands. This includes a rights component that enables the data modifications to be implemented across the one or more databases.

Abstract: The present invention relates to a method and a system for on-site and full-scale testing of wind turbine plants. In particular, the present invention relates to a method and a system applying resonance circuits tuned with the fundamental frequency, or harmonics thereof, of a power supply grid connected to a wind turbine plant to be tested. The wind turbine plant to be tested may remain connected to the power supply grid during on-site and full-scale testing.

Abstract: Control systems, sensors and methods for controlling the fuel concentration in a fuel cell or a fuel cell stack are provided. In certain examples, the control system may be configured to detect a performance degradation, and the fuel concentration provided to the fuel cell may be adjusted in response to detection of the performance degradation.

Abstract: A method of producing a mainly carbonate bonded article includes a step of providing an alkaline granular material having one or more alkaline earth metal silicate phases. The method includes a step of compacting the granular material to obtain a compact of the granular material. The porosity of the compact is smaller than or equal to 37% by volume. The intrinsic permeability of the compact is at least 1·10?12 cm2. The method also includes a reacting step arranged to form at least 5% by weight of carbonates (CO32?), by reacting the granular material with carbon dioxide in the presence of water, thus transforming the compact into the article. In the reacting step, the compact, being unsaturated with moisture at the beginning of the reacting step, is brought in an atmosphere having carbon dioxide. The atmosphere is at a temperature of at least 70° C. and at a pressure of at least 0.5 MPa. The pressure is also higher than the saturated vapor pressure of water at the temperature.

Abstract: A fuel cell housing comprising at least one surface configured to condense fluid from exhaust air passing over or through the surface and configured to return the condensed fluid to electrolyte of a fuel cell or fuel cell stack within the fuel cell housing is disclosed. Fuel cell assemblies comprising the fuel cell housing are also disclosed.

Abstract: The present invention relates to a method for controlling a voltage level of a power supply grid operationally connected to a source of electrical power, the method comprising the steps of determining a short circuit impedance of the power supply grid at a point of common coupling, calculating, using the determined short circuit impedance, a gain value of the power supply grid, and controlling the grid voltage level in accordance with the calculated gain value by applying said gain value as a gain parameter in a voltage controller. The method according to the present invention may be implemented as a method for configuring a voltage controller once and for all, or it may be implemented as a method for adaptively adjusting a gain of a voltage controller.

Abstract: Control systems, sensors and methods for controlling the fuel concentration in a fuel cell or a fuel cell stack are provided. In certain examples, the control system may be configured to detect a performance degradation, and the fuel concentration provided to the fuel cell may be adjusted in response to detection of the performance degradation.

Abstract: The present invention relates to a method of operating of a wind power plant comprising a circuit breaker and at least one wind turbine generator electrically connectable to an electrical grid through said circuit breaker, the method comprising the steps of detecting at least one condition for the circuit breaker to trip by means of a sensor; informing a control means of this detection prior to the circuit breaker disconnecting; and preparing the at least one wind turbine generator before said circuit breaker disconnects said at least one wind turbine generator from said electrical grid.