Abstract: The invention relates to a method of identifying N-terminal proBNP in a sample with at least two antibodies that detect different epitopes of the N-terminal proBNP. The method is used to differentiate or classify samples of healthy individuals and samples of patients of NYHA classes I to IV. The invention further relates to recombinant N-terminal proBNP, its use as standard in a method of identifying N-terminal proBNP, to antibodies that detect recombinant N-terminal proBNP and to their production.

Abstract: The invention concerns autoreactive peptides, peptide-MHC complexes, T cell subpopulations that react thereto as well as diagnostic and therapeutic applications of these compounds.

Abstract: The invention concerns autoreactive peptides, peptide-MHC complexes, T cell subpopulations that react thereto as well as diagnostic and therapeutic applications of these compounds.

Abstract: Methods for measurement of at least one advanced glycation endproduct (AGE) in a cerebrospinal fluid (CSF) sample and use of these methods in the assessment of neurodegenerative disease.

Abstract: The floating caliper of a disk brake has three bridge arms, which extend over the brake disk, wherein one of the bridge arms, preferably the middle arm (34), is bifurcated into two branches (34a, 34b).

Abstract: The floating caliper of a disk brake has three bridge arms, which extend over the brake disk, wherein one of the bridge arms, preferably the middle arm (34), is bifurcated into two branches (34a, 34b).

Abstract: The present invention relates to the field of detection and measurement of advanced glycosylation endproducts (AGEs), in particular to methods of selection and/or quality control of a reagent or a coated solid phase component appropriate for AGE-assays. It also relates to a process for production of an AGE-free solid phase component, the solid phase component, and to the use of such solid phase component.

Abstract: the invention concerns autoreactive peptides, peptide MHC complexes, t cell subpopulations which react therewith as well as diagnostic and therapeutic applications of these compounds.

Abstract: Supertwist liquid crystal displays having very short switching times are obtained if the nematic liquid crystal mixture contains at least one component chosen from group A consisting of compounds of the formulae AI to AVI: wherein R1 and R2 in each case independently of one another are each R and R is alkyl having 1-12 C atoms, wherein one or two non-adjacent CH2 groups can also be replaced by —O—, —CH═CH—, —CO—, —O—CO— or —CO—O—, and up to four other components.

Abstract: Supertwist liquid crystal displays having very short switching times are obtained if the nematic liquid crystal mixture contains at least one component chosen from group A consisting of compounds of the formulae AI to AVI: ##STR1## wherein R.sup.1 and R.sup.2 in each case independently of one another are each R and R is alkyl having 1-12 C atoms, wherein one or two non-adjacent CH.sub.2 groups can also be replaced by --O--, --CH.dbd.CH--, --CO--, --O--CO-- or --CO--O--, and up to four other components.

Abstract: In order to detect analytes with an immunological method by incubation with receptors and analysis of the complexes formed, a mixture of at least two monoclonal antibodies which are specifically bindable to the analyte and whose cross-reactivities are different are used for at least one of the receptors.

Abstract: Supertwist liquid-crystal displays having excellent properties are obtained using a nematic liquid-crystal mixture based on component A which contains one or more compounds of the formula IIa or IIb: ##STR1## on or more compounds of the formulae IIc to IIe: ##STR2## and one or more compounds of the formula IIf to IIh: and one or more compounds of the formula IIf to IIh: ##STR3## wherein R, R.sup.1, R.sup.2, L, Y, X and n are as defined herein.

Abstract: A device in a submersible pump or mixer prevents solid bodies from entering a housing containing a mechanical seal. The device has a helically formed groove so directed, that pollutant material is fed in a direction away from the mechanical seal, and the device has a cutting means to cut the pollutant material.

Abstract: There is described the use of pyrrothine derivatives of the general formula I ##STR1## wherein R.sub.1 and R.sub.3 signify hydrogen or methyl, R.sub.2 hydrogen, methyl or an acyl group with 1 to 5 carbon atoms and X and Y signify hydrogen, an equivalent of a physiolgically acceptable cation or together a single bond, for the inhibition of the allergen-induced degranulation of peripheral leukocytes.

Abstract: The present invention provides a process for the detection of the presence of an allergy and for the specific detection of the allergen responsible for the allergy, based on the cellular principle, wherein leukocytes of a sample to be investigated are incubated with an allergen or another stimulation factor of degranulation, such as anti-IgE, in an aqueous medium, the leukocytes are then separated off and the remaining solution is incubated with a compound of the general formula:Y--X--Cin which Y is an amino acid or a peptide containing 2 or 3 amino acids, the amino acids optionally carrying a conventional protective group on the amino end, X is arginine or lysine and C is a chromogenic residue, in the presence of a buffer effective at pH 6.3 to 8.0 and the liberation of the chromogenic residue is measured.

Abstract: Process for obtaining high yields of glycerol dehydrogenase from micro-organisms and glycerol dehydrogenase having a low K.sub.M value.

Abstract: The present invention provides a process for the determination of .beta.-lactamases by the use of 7-cyanoacetylaminocephalosporanic acid and measurement of the colored material thereby formed, wherein ammonium ions are added to the material to be tested, together with phosphate ions and/or an agent splitting off oxygen.The present invention also provides a reagent for the determination of .beta.-lactamases based upon 7-cyanoacetylaminocephalosporanic acid, which reagent additionally contains ammonium ions, together with phosphate ions and/or an agent splitting off oxygen.

Abstract: In a method for the determination of glutamate-oxalacetate transaminase or glutamate-pyruvate transaminase by the reaction of oxalacetate or pyruvate with glutamate, with formation of .alpha.-ketoglutarate in a buffered solution, the .alpha.-ketoglutarate formed is reacted with .gamma.-aminobutyrate in the presence of .gamma.-aminobutyrate transaminase with formation of succinate semialdehyde, NADP is reduced with the latter in the presence of succinate semialdehyde dehydrogenase to give NADPH, and the latter is measured either directly or after conversion with a tetrazolium salt and an electron carrier such as diaphorase, phenantroline methosulphate or phenazine methosulphate to a formazane dye.A reagent suited for use with this method contains .gamma.-aminobutyrate transaminase, succinate semialdehyde dehydrogenase, .gamma.-aminobutyrate, glutamate and buffer, as well as either oxalacetate or pyruvate, and optionally a tetrazolium salt, an electron carrier and a surface-active agent.

Abstract: A novel peroxidase for reduced nicotinamide-adenine-dinucleotide is provided which peroxidase oxidizes reduced nicotinamide-adenine-dinucleotide with hydrogen peroxide to give nicotinamide-adenine-dinucleotide and water and is characterized by a Michaelis constant K.sub.Mto hydrogen peroxide of 2.8.times.10.sup.-5 M andto reduced nicotinamide-adenine-dinucleotide of 1.7.times.10.sup.-5 M,measured at 25.degree. C. in 0.2M tris buffer of pH 6.0, containing 0.1M potassium acetate. The peroxidase can be prepared by liberating the enzyme from Streptococcus faecalis ATCC 8043 by digestion or by treatment with a surface-active agent and isolating same from the enzyme solution obtained. Hydrogen peroxide is determined in a simple reaction or in a coupled reaction with a specific oxidase by contacting the said peroxidase with the H.sub.2 O.sub.2 producing reaction mixture at a pH of from 6.0 to 9.0 and measuring the change of extinction as a measure of H.sub.2 O.sub.