Abstract: The present invention relates to a ceramic or metallic component including a first region having a first porosity ranging between 1 and 30%. The component includes a second region having a second porosity that is less than the first porosity. The component includes at least one graded transition between the first and second regions.

Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.

Abstract: A resident remotely operated vehicle may be deployed subsea by deploying a remotely operated vehicle (ROV) (200) configured to be disposed and remain resident subsea for an extended time where the ROV comprises an ROV electrical power connector port (202) to be operatively connected to an electrical power supply (700) dedicated to the ROV. An RTMS configured to be disposed subsea for an extended time is also deployed subsea (210), typically proximate the ROV. A subsea docking hub subsea is also deployed subsea proximate the RTMS and operatively connected to the ROV and the RTMS. In addition, an umbilical is connected from the subsea docking hub to a subsea structure and a signal supplied from the subsea structure to the ROV.

Abstract: Electrical power may be provided to a subsea system, which may include one or more battery packs, from a subsea power system comprising a surface buoy which comprises an electrical power generator and a surface buoy power outlet operatively in communication with the power generator; a subsea battery bank which comprises a predetermined set of batteries, a subsea battery bank power inlet operatively in communication with the surface buoy power outlet and with the predetermined set of batteries, and a subsea battery bank power outlet operatively in communication with the predetermined set of batteries. The subsea power system is deployed at sea, by way of example and not limitation including by use of an autonomous vehicle, and generates electrical power at the power generator which may be provided to the subsea battery bank or other structures requiring electrical power subsea.

Abstract: A system and method for cleaning an installed gas turbine engine is provided. The system may include a controller on an engine core, wherein the engine core defines a primary gas path and includes at least one airfoil extending into the primary gas path. The method may include initiating a cleaning program and directing a cleaning fluid toward the engine core in response to the initiation of the cleaning program. The method may further include initiating delivery of the cleaning fluid as a non-vaporized liquid within the primary gas path to the engine core.

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Abstract: An architectural building block including a generally triangular block having an outer wall, an inner wall disposed in substantially parallel configuration with respect to the outer wall and three side walls, each adjoining the outer wall and the inner wall. One of the side walls includes dual inverse mirror planes and each of the other two of which includes a single inverse mirror plane. At least one the side walls is configured to be positionable so as to mate with a side wall of an abuttingly disposed block, whereby curved structures may be constructed from a plurality of such blocks to form a dihedral angle between each set of two blocks. In one embodiment, the inner wall further includes at least one depression disposed on the inner wall of the block.

Abstract: A method of preparing a printing form precursor for printing, or a printed circuit board precursor or a semiconductor precursor, the method comprising the step of applying electromagnetic radiation having a pulse duration of not greater than 1×10?6 seconds, in an imagewise manner, to an imagable surface of the precursor. The imaging process may cause ablation of the coating of the precursor or permit its development in a developer. In each case the imaging radiation needs not be tuned to imaging chemistry (if any) present in the coating. Alternatively the imaging process may induce a change of hydrophilicity or hydrophobicity, or other change of state, of an uncoated substrate.

Abstract: A kidney viability assessment system (KVAS) is disclosed which provides objective and reliable tests to assess the viability of transplant or donor kidneys in vivo and predict their post-transplant outcomes. KVAS includes an optical device augmented by an intelligent algorithm that can evaluate the viability or quality of the donor kidney in a real-time, non-invasive way. In particular, it includes a handheld optical coherence tomography (OCT) imaging device and at least one processor configured for executing a set of instructions corresponding to an automatic image processing algorithm for quantification of kidney microstructures and functions. Handheld OCT can survey the entire surface of kidney, and the image processing algorithm automatically segments and quantifies the diameter and/or density of the kidney microstructures, blood flows, etc., and quantitative values are displayed in real-time on a display of the KVAS.

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Abstract: A damper seat for a ring damper that redirects axial loads and is disposed within a gas turbine engine with at least one disk rotatable about a rotational axis and having a disk neutral axis extending radially from the rotational axis.

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Abstract: Synthetic ether alkyl-lysophospholipids (APLs) provide an effective treatment for subjects suffering from cholinergic seizures. Among other uses, APLs may be used to treat the effects of epileptic seizures in particular cholinergic seizures caused by exposure to insecticides or chemical warfare nerve agent exposure. Edelfosine, an APL, has been show to be particularly effective in these areas.

Abstract: A moisture absorbent and decontaminant is provided. The moisture absorbent and decontaminant includes a receptacle. The receptacle is formed of a permeable material having a plurality of pores. The present invention includes at least first pellets, second pellets and third pellets. The pellets are enclosed within the receptacle. The pellets include a diameter larger than the diameter of the pores and thereby cannot escape the receptacle. The first pellets include an antimicrobial. The second pellets include an antifungal. The third pellets include a moisture absorber.

Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. The compounds provided herein can in other embodiments overcome the resistance conferred by single amino acid mutations at defined positions of bacterial Signal Peptidases (SPases) and in other embodiments provide for a broad spectrum of antibiotic bioactivity. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.

Abstract: Methods, devices, and computer programs are presented for creating a unified data stream from multiple data streams acquired from multiple devices. One method includes an operation for receiving activity data streams from the devices, each activity data stream being associated with physical activity data of a user. Further, the method includes an operation for assembling the unified activity data stream for a period of time. The unified activity data stream includes data segments from the data streams of at least two devices, and the data segments are organized time-wise over the period of time.

Abstract: A method of operating a voltage regulator including a source voltage rail and a plurality of output voltage rails, the method including: converting a source voltage on the source voltage rail to a respective output voltage on each output voltage rail; selecting an output voltage rail; comparing the output voltage on the selected output voltage rail to a reference voltage for the selected output voltage rail; and if the output voltage of the selected output voltage rail is less than the reference voltage for the selected output voltage rail, controlling the voltage regulator to increase the output voltage on the selected output voltage rail, wherein the frequency at which an output voltage rail is selected is dependent upon the rate at which the voltage regulator has previously increased the output voltage on that output voltage rail.

Abstract: Embodiments for presenting search content is provided herein. An embodiment includes, receiving an input string in a browser input receiver, presenting a list of identifiers and search queries, wherein at least a portion of each of the identifiers and search queries match the input string, and presenting one or more search results associated with a selected search query on a display or providing a HTTP request to retrieve content associated with a selected identifier, and presenting the content on the display.