Abstract: According to a first aspect of the invention there is provided a motion generator comprising an effector for applying forces, moments and movements to a payload relative to a surface connected to one or more elongate rigid struts, each strut being connected at one end thereof by a first joint to the effector and being connected at its other end by a second joint to an associated rocker, the rocker having a pivot axis, such that movement of a rocker about the pivot axis leads to movement of the effector, and forces applied to an associated rocker lead to forces being applied to the effector, in which the movement of a rocker and forces applied by the rocker are controlled by an actuator, the actuator being in the form of an elongate belt, cable, rope drive, or linear motor arranged to apply a force to a point on an associated rocker away from the pivot axis of the rocker.

Abstract: Provided herein are compositions, methods and uses that relate to an easy, accurate and reliable dual or duplex assay that determines both protein and nucleic acid amounts in a viral preparation in a single container and further determines full versus empty virion content.

Abstract: A method for detecting a leakage current path in a circuit is presented. The method may be used for identifying a leakage current path in an analog circuit and induced by the presence of a high voltage. The method includes several steps. A circuit design description of the circuit is received. The circuit design description is then interrogated to identify a set of candidate components having a first terminal coupled to a voltage source adapted to provide a voltage above a predefined value. Then for each electronic component in the set, a second terminal coupled to ground is searched. Upon identification of the second terminal coupled to ground a leakage path is reported. The method may be used for identifying a leakage current path induced by the presence of a high voltage in conjunction with the presence of parasitic devices.

Abstract: Provided herein are compositions, methods and uses that relate to an easy, accurate and reliable dual or duplex assay that determines both protein and nucleic acid amounts in a viral preparation in a single container and further determines full versus empty virion content.

Abstract: This invention relates to a three degree of freedom motion generator for moving a payload above the surface, the motion generator comprising a rotatable platform arranged for rotation on a circular guide above the surface, at least three linear guides extending ray-wise above the surface from a centre, each linear guide having a linear guide carriage moveable thereon, a peripheral guide carriage pivotally mounted on each linear guide carriage about the periphery of the rotatable platform, and a plurality of actuators, whereby at least one actuator may be operated to exert a force between a peripheral guide carriage on the circular guide and the rotatable platform. Other aspects include a motion system, and vehicle driving simulators including such a motion generator.

Abstract: According to a first aspect of the invention there is provided a motion generator comprising an effector for applying forces, moments and movements to a payload relative to a surface connected to one or more elongate rigid struts, each strut being connected at one end thereof by a first joint to the effector and being connected at its other end by a second joint to an associated rocker, the rocker having a pivot axis, such that movement of a rocker about the pivot axis leads to movement of the effector, and forces applied to an associated rocker lead to forces being applied to the effector, in which the movement of a rocker and forces applied by the rocker are controlled by an actuator, the actuator being in the form of an elongate belt, cable, rope drive, or linear motor arranged to apply a force to a point on an associated rocker away from the pivot axis of the rocker.

Abstract: A method to provide an automated circuit design tool that mitigates or overcomes the inefficiencies present in the prior art tools ensuring a more efficient use of computer resources and a reduction in the time taken to design a suitable circuit that meets the design specification is presented. The computer-implemented method of designing a circuit configuration of a circuit, has the following steps 1) providing a first set of circuit configurations comprising one or more circuit configurations, 2) simulating each, circuit configuration of the first set of circuit configurations. In addition, the steps include: 3) scoring each, circuit configuration of the first set of circuit configurations based on a design specification and the simulation, or simulations, of step 2), and 4) providing a second set of circuit configurations comprising one or more circuit configurations that are dependent on the scores as determined in step 3).

Abstract: There is disclosed a system that, when in operation, evaluates speech, for example evaluates a speech signal generated using a microphone to record an oral utterance.

Abstract: Provided herein are compositions, methods and uses that relate to an easy, accurate and reliable dual or duplex assay that determines both protein and nucleic acid amounts in a viral preparation in a single container and further determines full versus empty virion content.

Abstract: There is disclosed a system that, when in operation, evaluates speech, for example evaluates a speech signal generated using a microphone to record an oral utterance.

Abstract: An access network includes a twisted metallic pair connection over which data may be transmitted in accordance with a digital subscriber line protocol of transmission. The access network further includes an access network modem connected to the twisted metallic pair connection which is operable to transmit and receive signals thereover, in accordance with a digital subscriber line protocol of transmission. The access network further comprises a broadband speed estimation tool including a web server and/or an order processing sub-system 1120 and a line length, further deployment factors and speed determiner module 1170. The access network further comprises a line management subsystem which determines an appropriate value for each of one or more configuration parameters associated with the operation of the access network modem in dependence upon an estimated data rate and causes the access network modem to operate in accordance with the determined value or values of the configuration parameters.

Abstract: An access network includes a twisted metallic pair connection over which data may be transmitted in accordance with a digital subscriber line protocol of transmission. The access network further includes an access network modem connected to the twisted metallic pair connection which is operable to transmit and receive signals thereover, in accordance with a digital subscriber line protocol of transmission. The access network further comprises a broadband speed estimation tool including a web server and/or an order processing sub-system 1120 and a line length, further deployment factors and speed determiner module 1170. The access network further comprises a line management subsystem which determines an appropriate value for each of one or more configuration parameters associated with the operation of the access network modem in dependence upon an estimated data rate and causes the access network modem to operate in accordance with the determined value or values of the configuration parameters.

Abstract: Systems, methods, and non-transitory computer-readable media can display a collection of media content items. A pressure-based user interaction is received via a graphical user interaction, the pressure-based user interaction identifying a first media content item of the collection of media content items. A preview pane displaying the first media content item is displayed in response to the pressure-based user interaction. A position-based user interaction is received via the graphical user interface. A second media content item is displayed in the preview pane in response to the position-based user interaction.

Abstract: Process for producing C2+ alcohols from a methane-containing feedstock, by passing the methane-containing feedstock and CO2 to a non-oxidative reforming process to produce a product stream containing CO, H2 and CO2, optionally in the presence of steam, provided that where steam is present in the feed to the reforming process, the steam and CO2 are present in a molar ratio of less than 5:1. The CO, H2 and CO2 stream is passed to a bacterial fermentation step where it is converted to a liquid product stream containing one or more C2+ alcohols and a gaseous product stream containing CO, H2 and CO2. The fermentation step is operated to provide a conversion of CO of at least 60%. CO, H2 and CO2 are recycled from the gaseous product stream to the reforming process such that the H2 reacts with carbon dioxide in the reforming process.

Abstract: Process for the production of leather, wherein pelts, pickled pelts or semifinished products are treated with at least one copolymer (A) which is obtainable by copolymerization of the following comonomers: (a) at least one ethylenically unsaturated C3-C10-carboxylic acid or at least one ethylenically unsaturated C4-C10-dicarboxylic acid or its anhydride, (b) at least one (meth)acrylate of an ?-branched C3-C10-alkanol, (c) at least one (meth)acrylate of a primary C4-C20-alkanol.

Abstract: The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides.

Abstract: Cell-free extracts, methods for producing these extracts, methods for using these extracts, compositions that facilitate production of these extracts and kits that contain these extracts are provided. By increasing or decreasing certain gene products through, for example, the use of siRNA or mimics, one can develop mammalian cell-free extracts that have desired levels of efficiency.

Abstract: The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.

Abstract: The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.

Abstract: A process is provided for producing syngas that is effective for use in downstream processes. The process for producing syngas includes operating a gasification apparatus in a start-up mode until the gasification apparatus and equipment downstream of the gasification apparatus are adequately warmed up to a first target temperature. Upon reaching a first target temperature, the process is then operated in a production mode to produce a second syngas with a higher CO/CO2 molar ratio. Operation in a start-up mode until reaching a first target temperature, provides a process that is effective for reducing fouling in downstream equipment and for providing a second syngas can be more effectively cooled and cleaned.