Abstract: Provided herein are combination dosing regimens comprising administering an antibody-drug conjugate (ADC) and a hyaluronidase. In embodiments, the hyaluronidase is a soluble hyaluronidase. In embodiments, the ADC and hyaluronidase are administered subcutaneously. Pharmaceutical compositions comprising an ADC and a hyaluronidase are also provided. In embodiments, the dosing regimens and the pharmaceutical compositions are used in a method of treating or preventing cancer, a cardiometabolic disease/disorder, an inflammatory disease/disorder, or an autoimmune disease/disorder in a patient in need thereof.

Abstract: Methods of forming microelectronic structures are described. Embodiments of those methods include forming a nanowire device comprising a substrate comprising source/drain structures adjacent to spacers, and nanowire channel structures disposed between the spacers, wherein the nanowire channel structures are vertically stacked above each other.

Abstract: In some examples, a method comprises determining, at an electronic device having a first component of a first component type, a unique identifier associated with the first component. In some examples, in accordance with a determination that the unique identifier does not match the expected identifier of the component of the first component type in the electronic device, determining that the first component associated with the unique identifier satisfies one or more eligibility criteria. In some examples, in accordance with the determination that the first component associated with the unique identifier satisfies the one or more eligibility criteria, authenticating an association of the first component with the electronic device, including updating an installation counter associated with the first component, and updating the expected identifier for the component of the first type based on the unique identifier of the first component.

Abstract: Methods of forming microelectronic structures are described. Embodiments of those methods include forming a nanowire device comprising a substrate comprising source/drain structures adjacent to spacers, and nanowire channel structures disposed between the spacers, wherein the nanowire channel structures are vertically stacked above each other.

Abstract: Presented here is a system and method for creating easy-to-understand notifications of the vehicle state. The notification can be visual or can be auditory and can indicate to the user the vehicle state even when the user's attention is directed elsewhere. The indication can serve to attract the user's attention before more involved information is presented to the user, such as text, or the indication can serve to communicate to the user the vehicle state in an easy-to-understand way such as using color-coded displays or audio indications. The intensity of the indication can be adjusted based on the likelihood that indication will be perceived by the user by, for example, measuring ambient light and/or ambient noise. Reducing the intensity of the indication conserves energy of an energy source associated with the vehicle.

Abstract: Described herein are methods and kits for authentication of botanical DNA fragments isolated from processed botanical products, including dietary supplements or nutraceutical compositions including botanical extracts.

Abstract: Systems and methods for storing and recovering data for a device are described. In one embodiment, factory generated calibration data can be generated, sealed and restored securely even if two sensors in two different devices, such as a first ambient light sensor and a second ambient light sensor have the same sensor identifier. In one embodiment, a device transmits a database key to cause storage or recovery of the calibration data, and the database key includes a sensor identifier and a public cryptographic key of the device.

Abstract: In some examples, a method comprises determining, at an electronic device having a first component of a first component type, a unique identifier associated with the first component. In some examples, in accordance with a determination that the unique identifier does not match the expected identifier of the component of the first component type in the electronic device, determining that the first component associated with the unique identifier satisfies one or more eligibility criteria. In some examples, in accordance with the determination that the first component associated with the unique identifier satisfies the one or more eligibility criteria, authenticating an association of the first component with the electronic device, including updating an installation counter associated with the first component, and updating the expected identifier for the component of the first type based on the unique identifier of the first component.

Abstract: In some examples, a method comprises determining, at an electronic device having a first component of a first component type, a unique identifier associated with the first component. In some examples, in accordance with a determination that the unique identifier does not match the expected identifier of the component of the first component type in the electronic device, determining that the first component associated with the unique identifier satisfies one or more eligibility criteria. In some examples, in accordance with the determination that the first component associated with the unique identifier satisfies the one or more eligibility criteria, authenticating an association of the first component with the electronic device, including updating an installation counter associated with the first component, and updating the expected identifier for the component of the first type based on the unique identifier of the first component.

Abstract: A processor includes a scalar processor core and a vector coprocessor core coupled to the scalar processor core. The scalar processor core is configured to retrieve an instruction stream from program storage, and pass vector instructions in the instruction stream to the vector coprocessor core. The vector coprocessor core includes a register file, a plurality of execution units, and a table lookup unit. The register file includes a plurality of registers. The execution units are arranged in parallel to process a plurality of data values. The execution units are coupled to the register file. The table lookup unit is coupled to the register file in parallel with the execution units. The table lookup unit is configured to retrieve table values from one or more lookup tables stored in memory by executing table lookup vector instructions in a table lookup loop.

Abstract: A processor includes a scalar processor core and a vector coprocessor core coupled to the scalar processor core. The scalar processor core is configured to retrieve an instruction stream from program storage, and pass vector instructions in the instruction stream to the vector coprocessor core. The vector coprocessor core includes a register file, a plurality of execution units, and a table lookup unit. The register file includes a plurality of registers. The execution units are arranged in parallel to process a plurality of data values. The execution units are coupled to the register file. The table lookup unit is coupled to the register file in parallel with the execution units. The table lookup unit is configured to retrieve table values from one or more lookup tables stored in memory by executing table lookup vector instructions in a table lookup loop.

Abstract: Presented here is a system and method for creating easy-to-understand notifications of the vehicle state. The notification can be visual or can be auditory and can indicate to the user the vehicle state even when the user's attention is directed elsewhere. The indication can serve to attract the user's attention before more involved information is presented to the user, such as text, or the indication can serve to communicate to the user the vehicle state in an easy-to-understand way such as using color-coded displays or audio indications. The intensity of the indication can be adjusted based on the likelihood that indication will be perceived by the user by, for example, measuring ambient light and/or ambient noise. Reducing the intensity of the indication conserves energy of an energy source associated with the vehicle.

Abstract: Presented here is a system and method for creating easy-to-understand notifications of the vehicle state. The notification can be visual or can be auditory and can indicate to the user the vehicle state even when the user's attention is directed elsewhere. The indication can serve to attract the user's attention before more involved information is presented to the user, such as text, or the indication can serve to communicate to the user the vehicle state in an easy-to-understand way such as using color-coded displays or audio indications. The intensity of the indication can be adjusted based on the likelihood that indication will be perceived by the user by, for example, measuring ambient light and/or ambient noise. Reducing the intensity of the indication conserves energy of an energy source associated with the vehicle.

Abstract: A mobile computing device comprising a Light Emitting Diode (LED) display; including a display panel and a substrate, and two or more controller integrated circuits mounted (ICs) mounted on the substrate to directly drive a serial interface into the display panel.

Abstract: Methods of forming microelectronic structures are described. Embodiments of those methods include forming a nanowire device comprising a substrate comprising source/drain structures adjacent to spacers, and nanowire channel structures disposed between the spacers, wherein the nanowire channel structures are vertically stacked above each other.

Abstract: Methods of forming microelectronic structures are described. Embodiments of those methods include forming a nanowire device comprising a substrate comprising source/drain structures adjacent to spacers, and nanowire channel structures disposed between the spacers, wherein the nanowire channel structures are vertically stacked above each other.

Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same.

Abstract: A processor includes a scalar processor core and a vector coprocessor core coupled to the scalar processor core. The scalar processor core is configured to retrieve an instruction stream from program storage, and pass vector instructions in the instruction stream to the vector coprocessor core. The vector coprocessor core includes a register file, a plurality of execution units, and a table lookup unit. The register file includes a plurality of registers. The execution units are arranged in parallel to process a plurality of data values. The execution units are coupled to the register file. The table lookup unit is coupled to the register file in parallel with the execution units. The table lookup unit is configured to retrieve table values from one or more lookup tables stored in memory by executing table lookup vector instructions in a table lookup loop.

Abstract: A processor includes a scalar processor core and a vector coprocessor core coupled to the scalar processor core. The scalar processor core is configured to retrieve an instruction stream from program storage, and pass vector instructions in the instruction stream to the vector coprocessor core. The vector coprocessor core includes a register file, a plurality of execution units, and a table lookup unit. The register file includes a plurality of registers. The execution units are arranged in parallel to process a plurality of data values. The execution units are coupled to the register file. The table lookup unit is coupled to the register file in parallel with the execution units. The table lookup unit is configured to retrieve table values from one or more lookup tables stored in memory by executing table lookup vector instructions in a table lookup loop.

Abstract: An exemplary system, method and computer-accessible medium for determining a risk of developing breast cancer for a patient(s) can include, for example receiving an image(s) of an internal portion(s) of a breast of the patient(s), and determining the risk by applying a neural network(s) to the image(s). The neural network can be a convolutional neural network (CNN). The CNN can include a plurality of layers. Each of the layers can have a different number of feature channels. The CNN can include at least four layers. A first layer of the at least four layers can have 256×256×16 feature channels, a second layer of the at least four layers can have 128×128×32 feature channels, a third layer of the at least four layers can have 64×64×64 feature channels, and a fourth layer of the at least four layers can have 32×32×128 feature channels.