Abstract: The present invention provides a compound for use in treating cancer cachexia in a subject, wherein the compound is of general formula I: (I) or a pharmaceutically acceptable salt or solvate thereof; wherein —R1 is a C1-C6 alkyl group, which alkyl group carries up to five —OR2 substituents, wherein R2 represents hydrogen, or C1-C6 alkyl or wherein —OR2 represents a (R)-3-hydroxybutyrate moiety; or —R1 is a moiety derived from an alcohol HORI, wherein said alcohol is a sugar. Typically, the invention also provides treatment of the conditions associated with cachexia, such as muscle wasting.

Abstract: Methods, systems, and devices for wireless communications are described. In some systems, a user equipment (UE) may transmit assistance information to a base station to request an update or a modification to one or more communication parameters configured at the UE. Such communication parameters may include a quantity of uplink multiple-input multiple-output (MIMO) layers, a quantity of downlink MIMO layers, a minimum scheduling offset, a maximum quantity of component carriers, or a maximum aggregated bandwidth for a secondary cell group (SCG). In some implementations, the UE may transmit the assistance information requesting the update or modification to one or more of such communication parameters based on detecting that the UE satisfies one or more triggering conditions or thresholds.

Abstract: A system includes a plurality of modular subassemblies and a plate; wherein each modular subassembly comprises an enclosure and a plurality of optical components aligned to the enclosure, and each enclosure comprises a plurality of mounting structures; and wherein each modular subassembly is mechanically coupled to the plate by attachment of a mounting structure of the modular subassembly directly to a corresponding mounting structure located on the plate, such that by mechanically coupling each modular subassembly to the plate using the mounting structure of the modular subassembly and the corresponding mounting structure on the plate, adjacent modular subassemblies are aligned to each other upon such attachment, and wherein two of the modular subassemblies mechanically coupled to the plate are also attached to each other by mechanically coupling an alignment structure on one of the two modular subassemblies to a respective alignment structure on the other of the two modular subassemblies.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is amenable to automation. In particular, the method of the present invention comprises a method of purification carried out by means of solid phase extraction (SPE) alone.

Abstract: A system and method for installing bird flight diverters on wires, such as power lines and guy wires, is described. The system and method include the use of a robotic line crawler onto wires where the line crawler is configured to place bird flight diverters on the wire as the line crawler travels along the wire.

Abstract: Systems and methods are described for stringing spans of cable, in particular, electric power transmission lines between utility poles using a robotic device suspended from an unmanned aerial vehicle (“UAV”). In some aspects, a thrust assembly suspended by a UAV pulls the cable from pole to pole whereas in other aspects, an aerial robot integrating the functions of the thrust assembly and the UAV pulls the cable from pole to pole.

Abstract: A system includes a plurality of modular subassemblies and a plate; wherein each modular subassembly comprises an enclosure and a plurality of optical components aligned to the enclosure, and each enclosure comprises a plurality of mounting structures; and wherein each modular subassembly is mechanically coupled to the plate by attachment of a mounting structure of the modular subassembly directly to a corresponding mounting structure located on the plate, such that by mechanically coupling each modular subassembly to the plate using the mounting structure of the modular subassembly and the corresponding mounting structure on the plate, adjacent modular subassemblies are aligned to each other upon such attachment, and wherein two of the modular subassemblies mechanically coupled to the plate are also attached to each other by mechanically coupling an alignment structure on one of the two modular subassemblies to a respective alignment structure on the other of the two modular subassemblies.

Abstract: A razor cartridge having a housing including a frame with a non-cutting element, a guard and a cap. The non-cutting element has a plurality of open slots defined between a pair of projections disposed next to each other. A first razor blade is positioned between the guard and the non-cutting element and has a blade edge extending toward the guard. The non-cutting element is spaced apart from the first razor blade. A second razor blade is positioned between the non-cutting element and the cap and has a blade edge extending toward the guard. The non-cutting element is spaced apart from the second razor blade. A first rinse-through gap between the first razor blade and the non-cutting element of about 0.05 mm to about 0.5 mm. A second rinse-through gap between the second razor blade and the non-cutting of about 0.05 mm to about 0.6 mm.

Abstract: A flow cell for a colour measurement system is described that includes a body with a fluid inlet and a fluid outlet linked by a fluid pathway. An entrance window for allowing light transmission into the flow cell is provided, along with a coupler configured to couple a light source to the flow cell. The entrance window is fixedly coupled to the body of the flow cell, and the coupler is carried by a coupler mount that attaches to the body of the flow cell independently of the entrance window.

Abstract: The present disclosure generally relates to articles and methods for handling food items. In one aspect, an article for receiving or holding a food item comprises: a blade; and a rim extending along at least one side of the blade. In another aspect, a method of handling a food item using an article comprises a blade and a rim extending along at least one side of the blade, the method comprising: gripping or holding a part of the rim by hand; causing the food item to be placed onto the blade; and moving the article containing the food item therein to a desired location.

Abstract: Methods of forming an article from a molten plastic composition comprising a polymer and a blowing agent. The methods include injecting the molten plastic composition into a mould, allowing the plastic composition to form a first solid skin adjacent to an in contact with a first cavity-forming surface of the mould and a second solid skin adjacent to and in contact with a second cavity-forming surface of the mould, and then opening the mould before the molten plastic composition between the first and second solid skins in at least one portion of the circumference of a region of the mould cavity defining an annular cross-section of the cavity has solidified.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).

Abstract: A rotor system for aerial vehicles where two or more rotor systems are used in a coaxial or tandem arrangement on the aerial vehicle.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).

Abstract: A method of purifying a composition comprising a group B adenovirus, for example comprising a purification step of: subjecting a composition comprising said group B adenovirus to diafiltration employing a diafiltration-buffer with a conductivity of at least 180 mScm?1, for example a conductivity of 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, or 290 mScm?1. Also provided is a composition obtained using the purification method disclosed herein.

Abstract: A system includes a plurality of modular subassemblies and a plate; wherein each modular subassembly comprises an enclosure and a plurality of optical components aligned to the enclosure, and each enclosure comprises a plurality of mounting structures; and wherein each modular subassembly is mechanically coupled to the plate by attachment of a mounting structure of the modular subassembly directly to a corresponding mounting structure located on the plate, such that by mechanically coupling each modular subassembly to the plate using the mounting structure of the modular subassembly and the corresponding mounting structure on the plate, adjacent modular subassemblies are aligned to each other upon such attachment, and wherein two of the modular subassemblies mechanically coupled to the plate are also attached to each other by mechanically coupling an alignment structure on one of the two modular subassemblies to a respective alignment structure on the other of the two modular subassemblies.

Abstract: A collaborative authoring application provides an authoring environment in which two or more users can edit a document concurrently. Each user edits a copy of the document, sends updates to a master copy of the document, and receives updates from the master copy of the document. The authoring environment generally inhibits the users from providing conflicting editing instructions to the master copy of the document. For example, each user can generate a content lock about one or more data units within the document. The authoring environment may synchronize content locks automatically and content only at the request of the user.

Abstract: Method of forming an article from a molten plastic composition including a polymer and a blowing agent.

Abstract: A system includes a plurality of modular subassemblies and a plate; wherein each modular subassembly comprises an enclosure and a plurality of optical components aligned to the enclosure, and each enclosure comprises a plurality of mounting structures; and wherein each modular subassembly is mechanically coupled to the plate by attachment of a mounting structure of the modular subassembly directly to a corresponding mounting structure located on the plate, such that by mechanically coupling each modular subassembly to the plate using the mounting structure of the modular subassembly and the corresponding mounting structure on the plate, adjacent modular subassemblies are aligned to each other upon such attachment, and wherein two of the modular subassemblies mechanically coupled to the plate are also attached to each other by mechanically coupling an alignment structure on one of the two modular subassemblies to a respective alignment structure on the other of the two modular subassemblies.