Patents by Inventor Peter D'Arpa

Peter D'Arpa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloned human topoisomerase I: CDNA expression, and use for autoantibody detection
    Patent number: 5070192
    Abstract: The invention relates to cDNA molecules coding for eukaryotic topoisomerase I polypeptide. The invention provides cDNA mlecules comprising a part of the cDNA sequence of topoisomerase I which encode at least one epitope for autoantibodies to eukaryotic topoisomerase I. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for eukaryotic topoisomerase I. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for eukaryotic topoisomerase I. In another embodiment, the invention provides for the detection of autoantibodies to eukaryotic topoisomerase I using the eukaryotic topoisomerase I polypeptides coded for by the cDNA molecules of the invention.
    Type: Grant
    Filed: March 23, 1988
    Date of Patent: December 3, 1991
    Assignee: The Johns Hopkins University
    Inventors: William C. Earnshaw, Peter D'Arpa