Patents by Inventor Peter D'HOYE

Peter D'HOYE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240299510
    Abstract: The present disclosure describes the grafting of epitope residues from human PCSK9 to non-human PCSK9 or PCSK9 structural homologs and elimination of 9-mers oligopeptides that are found in human protein to reduce self-targeting response. Anti-genicity of the epitope-scaffold constructs was demonstrated toward anti-human PCSK9 antibodies. similar to wild type human PCSK9. It was shown that disclosed PCSK9 immunogens could significantly reduce LDL and cholesterol levels in immunized mice.
    Type: Application
    Filed: December 31, 2021
    Publication date: September 12, 2024
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Peter D. Kwong, Gwo-Yu Chuang, Baoshan Zhang, Wing-Pui Kong, Yiran Wang, Cara Chao, John R. Mascola, Li Ou, Tongqing Zhou, Yongping Yang, Bohan Liu, Cheng Cheng, Daniel W. Biner, Reda Rawi
  • Patent number: 12086379
    Abstract: At a computer system, in response to detecting a respective user input: if the respective user input meets first criteria requiring the one or both hands of the user maintain a first grip while a first type of movement of the one or both hands is detected, the computer system moves a virtual object in a three-dimensional environment relative to the three-dimensional environment in accordance with the movement of the one or both hands in the three-dimensional environment; and if the respective user input meets second criteria requiring the one or both hands of the user maintain a second grip while a second type of movement of the one or both hands is detected, the computer system replaces the view of the three-dimensional environment corresponding to a first viewpoint with a view of the three-dimensional environment corresponding to a second viewpoint different from the first viewpoint.
    Type: Grant
    Filed: September 14, 2023
    Date of Patent: September 10, 2024
    Assignee: APPLE, INC
    Inventors: Philipp Rockel, William A. Sorrentino, III, Stephen O. Lemay, Peter D. Anton
  • Publication number: 20240293505
    Abstract: Methods are provided for treating an individual with cytotoxic T lymphocyte exhaustion by administering an effective dose of an annexin V agent. In some embodiments, the individual undergoing treatment is infected with HIV. The individual may be treated with highly active antiretroviral therapy (HAART).
    Type: Application
    Filed: March 29, 2022
    Publication date: September 5, 2024
    Inventors: Francis Gerard Blankenberg, Peter D. Katsikis
  • Publication number: 20240289007
    Abstract: The present disclosure generally relates to methods and user interfaces for adjusting device settings.
    Type: Application
    Filed: January 9, 2024
    Publication date: August 29, 2024
    Inventors: Christopher D. MCKENZIE, William A. SORRENTINO, III, Richard D. LYONS, Lee S. BROUGHTON, Adam L. AMADIO, Peter D. ANTON, Kristi E. BAUERLY, Stephen O. LEMAY, Karen EL ASMAR, Lynn I. STREJA
  • Publication number: 20240285749
    Abstract: Vaccines that elicit broadly protective anti-influenza antibodies. Some vaccines comprise nanoparticles that display HA trimers from influenza virus on their surface. The nanoparticles are fusion proteins comprising a monomeric subunit (e.g., ferritin) joined to the stem region of an influenza HA protein. The fusion proteins self-assemble to form the HA-displaying nanoparticles. The vaccines comprise only the stem region of an influenza HA protein joined to a trimerization domain. Also provided are fusion proteins, and nucleic acid molecules encoding such proteins, and assays using nanoparticles of the invention to detect anti-influenza antibodies.
    Type: Application
    Filed: April 26, 2024
    Publication date: August 29, 2024
    Applicant: The United States of America, as represented by thew Secretary, Department of Health and Human Servi
    Inventors: John R. Mascola, Jeffrey C. Boyington, Hadi M. Yassine, Peter D. Kwong, Barney S. Graham, Masaru Kanekiyo
  • Patent number: 12072521
    Abstract: A fiber includes a core and cladding, both of which may have temperature dependent indices of refraction. The materials and size of the core and cladding may be selected such that as the temperature of the core and/or cladding is heated above room temperature, the fiber transitions from supporting multimode optical waveguiding to supporting single mode waveguiding.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: August 27, 2024
    Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, CLEMSON UNIVERSITY
    Inventors: Peter D. Dragic, John Ballato, Thomas W. Hawkins
  • Patent number: 12071943
    Abstract: A fluid sensing safety may include a pump, and a prime mover configured to drive the pump. A fluid vessel may be associated with the pump. A sensing system may be configured to determine the presence of fluid within the fluid vessel.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: August 27, 2024
    Assignee: FNA GROUP, INC.
    Inventors: Gus Alexander, Chris Alexander, Richard J. Gilpatrick, Peter D. Joseph, Robert E. Dowd, Shawn M. Mulkins
  • Publication number: 20240282597
    Abstract: Improved puddle processes and methods are provided herein for retaining a processing liquid on a surface of a semiconductor substrate. More specifically, improved methods are provided herein for retaining a puddle within a center region of a semiconductor substrate while the substrate is stationary, or rotating at relatively low rotational speeds. In the disclosed embodiments, a puddle is retained within a center region of the semiconductor substrate by a thin film, which is deposited within a peripheral edge region of the substrate before a processing liquid is dispensed within the center region of the substrate to form the puddle.
    Type: Application
    Filed: February 21, 2023
    Publication date: August 22, 2024
    Inventors: Shan Hu, Peter D'Elia
  • Patent number: 12063590
    Abstract: System/methods of Carrier Aggregation are disclosed. According to some embodiments, a system/method comprises a first transmitter and a second transmitter, that are connected therebetween, and configured to perform operations comprising: wirelessly transmitting to a destination device first data via the first transmitter, using frequencies that are allocated for use by cellular communications; and, responsive to a size of data that is to be transmitted to the destination device and responsive to a distance between the destination device and the second transmitter, wirelessly transmitting to the destination device second data via the second transmitter, using frequencies that are allocated for use by cellular communications; wherein, according to some embodiments, the first transmitter uses a first air interface and the second transmitter uses a second air interface that comprises a variant of the first air interface.
    Type: Grant
    Filed: February 26, 2024
    Date of Patent: August 13, 2024
    Inventors: Peter D. Karabinis, Dimitrios P. Karabinis
  • Patent number: 12060768
    Abstract: Pressure-activated valve assemblies and methods to remotely activate a valve are disclosed. A pressure-activated valve assembly includes a valve, a latch mechanism configured to shift the valve to an open position, and a pressure-activated indexing mechanism that is initially engaged to the latch mechanism. The pressure-activated indexing mechanism is initially in an unarmed mode. After the pressure-activated indexing mechanism is in an armed mode, applying at least one cycle of threshold pressure to the pressure-activated indexing mechanism disengages the latch mechanism to shift the valve to the open position. The pressure-activated valve assembly also includes a remote-activated downhole system configured to receive an activation pressure signal having a signature profile, and in response to receiving the activation pressure signal, arm the pressure-activated indexing mechanism.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: August 13, 2024
    Assignee: HALLIBURTON ENERGY SERVICES, INC
    Inventor: Peter D W Inglis
  • Patent number: 12056921
    Abstract: An agricultural machine includes a product application system comprising a plurality of actuatable applicator mechanisms. Each actuatable applicator mechanism is configured to apply a substance on an agricultural surface. An imaging system includes an imaging capture component configured to capture of an image of plant matter on the agricultural surface, and an image processing module configured to determine a characteristic of the plant matter based on the image. A control system is configured to control one or more of the actuatable applicator mechanisms to apply the substance on the agricultural surface based on the determined characteristic, obtain diagnostic data indicative of operation of the imaging system, and generate a user interface display that displays a representation of the diagnostic data.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: August 6, 2024
    Assignee: Deere & Company
    Inventors: Michelle Kwak, Devin L. Mangus, Barbra Cavanaugh, Peter D. Martinson, Andrea Maria Anna Agarwal, Michael Carley
  • Publication number: 20240254298
    Abstract: In some embodiments, a polymer film includes a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. In some embodiments, a polymer film includes a base layer of a first composition of poly(ethylene-vinyl acetate), a surface layer at a surface of the base layer, and a coating layer of a second composition of a copolymer of glycerol and sebacic acid. The surface layer includes surface hydroxy groups converted from acetate groups of the poly(ethylene-vinyl acetate). The second composition is attached to the surface layer by ester bonds between carboxyl groups of the copolymer and the hydroxy groups. A single-use bioreactor bag includes a polymer film including a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. A method of modifying a poly(ethylene-vinyl acetate) film includes converting acetate groups at a first surface of the poly(ethylene-vinyl acetate) film to hydroxy groups.
    Type: Application
    Filed: March 6, 2024
    Publication date: August 1, 2024
    Inventors: Peter D. Gabriele, Jeremy J. Harris, Scott Radzinski, Brian Ginn, Ryan R. Smalley
  • Publication number: 20240257441
    Abstract: A computer system displays a first view of a three-dimensional environment including a first representation of a first portion of a physical environment. While displaying the first view, the computer system detects movement of a first user from a first location to a second location of the physical environment, and in response: if the second location corresponds to a first type of exercise, the computer system replaces at least a portion of a second representation of a second portion of the physical environment that includes the second location with virtual content corresponding to the first type of exercise; and if the second location corresponds to a second type of exercise, the computer system replaces at least a portion of a third representation of a third portion of the physical environment that includes the second location with virtual content corresponding to the second type of exercise.
    Type: Application
    Filed: February 5, 2024
    Publication date: August 1, 2024
    Inventors: William A. Sorrentino, III, Gary I. Butcher, Wan Si Wan, Richard R. Dellinger, Giancarlo Yerkes, Stephen O. Lemay, Peter D. Anton
  • Publication number: 20240257486
    Abstract: The present disclosure generally relates to techniques for interacting with virtual avatars and/or user representations.
    Type: Application
    Filed: December 20, 2023
    Publication date: August 1, 2024
    Inventors: Karen EL ASMAR, Amy E. DEDONATO, Stephen O. LEMAY, Peter D. ANTON, William A. SORRENTINO, III, Wesley M. HOLDER, Jason D. RICKWALD
  • Patent number: 12049371
    Abstract: A method for building an article array comprised of (n) rows of articles, as disclosed herein.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: July 30, 2024
    Assignee: DYCO, INC.
    Inventors: Peter D. Yohe, Benjamin M. Kuznicki, Justin L. Mowery
  • Patent number: 12044102
    Abstract: A method for sealing a borehole, that includes lowering a plug into the borehole, where the plug includes a sealing element, a reservoir that includes a liquid, and a one-way valve connected to the reservoir, causing the sealing element to undergo sealing element expansion, where the sealing element expansion causes the sealing element to make circumferential contact with a casing of the borehole, and where the sealing element expansion causes the sealing element to create a void.
    Type: Grant
    Filed: August 22, 2023
    Date of Patent: July 23, 2024
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Scott Wallace, Barry Main, Peter D W Inglis
  • Publication number: 20240238478
    Abstract: A process forms an implantable product including poly(glycerol sebacate) urethane (PGSU) loaded with an active pharmaceutical ingredient (API). The process includes homogeneously mixing a flowable poly(glycerol sebacate) (PGS) resin with the API and a catalyst to form a resin blend. The process also includes homogeneously combining the resin blend with an isocyanate to form a reaction mixture and injecting the reaction mixture to form the PGSU loaded with the API. An implantable product includes a PGSU loaded with an API. In some embodiments, the implantable product includes at least 40% w/w of the API, and the implantable product releases the API by surface degradation of the PGSU at a predetermined release rate for at least three months under physiological conditions. In some embodiments, the PGSU is formed from a PGS reacted with an isocyanate at an isocyanate-to-hydroxyl stoichiometric (crosslinking) ratio in the range of 1:0.25 to 1:1.25.
    Type: Application
    Filed: January 29, 2024
    Publication date: July 18, 2024
    Inventors: Stephanie Reed, Carissa Smoot, Dennis Shull, Todd Crumbling, John D'Ottavio, Peter D. Gabriele, Jeremy J. Harris, Charles Brendan Nicholson, Jared Ely
  • Patent number: 12040311
    Abstract: A method for debonding a bonded part includes attaching a handle to a third side of a first substrate of the bonded part with an adhesive layer. The bonded part has a plurality of inter-substrate bond structures that couple a first side of the first substrate to a second side of a second substrate. The third side of the first substrate is opposite the first side. The first substrate and the second substrate have different thicknesses. The method includes absorbing a solvent into the adhesive layer, swelling the adhesive layer in response to the absorbing of the solvent, bending the first substrate in response to the swelling, and breaking a plurality of thermocompression bonds between the plurality of inter-substrate bond structures and the second side of the second substrate in response to the bending to debond the first substrate.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: July 16, 2024
    Assignee: The Boeing Company
    Inventors: Peter D. Brewer, Chia-Ming Chang, Sevag Terterian, Charbel Abijaoude, Diego Eduardo Carrasco
  • Patent number: 12036500
    Abstract: An exhaust and filtration assembly includes: a housing; an exhaust vent configured to guide unfiltered air out of the exhaust and filtration assembly; a filter assembly configured to filter air and guide the filtered air out of the exhaust and filtration assembly; an exhaust assembly configured to direct raw air from an entry port of the exhaust and filtration assembly and direct air out of the exhaust vent without the air having been filtered; and a controller comprising computing logic configured to control so that only one of air filtration and raw air exhaust occurs at any given time.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: July 16, 2024
    Assignee: HOMEWERKS WORLDWIDE, LLC
    Inventors: Peter D. Berkman, Michael J. Malaker, Deborah Holtkamp, Huang XiaoYing, He LiTing, Lin TiaoHao, Zhang Ruilin
  • Patent number: 12041537
    Abstract: Embodiments of systems/methods are disclosed wherein an auxiliary device, that is attached to a person, is configured to function in cooperation with a smartphone that is used by the person. According to some embodiments, over a first interval of time, the auxiliary device comprises a first auxiliary device that is configured to perform first monitoring or measurements and is further configured to wirelessly transmit information to the smartphone comprising results of said first monitoring or measurements. Further, over a second interval of time, the auxiliary device comprises a second auxiliary device, that is physically distinct from the first auxiliary device, is configured to perform second monitoring or measurements and is further configured to wirelessly transmit information to the smartphone comprising results of said second monitoring or measurements.
    Type: Grant
    Filed: December 27, 2023
    Date of Patent: July 16, 2024
    Inventors: Peter D. Karabinis, Dimitrios P. Karabinis