Abstract: An output module includes an output for switching a load and includes a switch that switches a switching voltage to the output to cause a load current to flow, wherein the module includes a measuring device that provides a monitoring signal profile that maps a signal profile of the load current based on the switching voltage, an analyzer that compares, at least at points, the monitoring signal profile with a switch-on characteristic curve characterizing the load, and a diagnostic device that generates a maintenance notification when the comparison exceeds a specifiable deviation.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: The present invention relates to compounds that inhibit KRas G12D, In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A method for operating an industrial control system that has an automation controller with a sequential program, an actuator which actuates a switching component of the power electronics, and an input module, wherein activation and deactivation operations of the switching component cause electromagnetic interference that corrupts a measured value recorded via the input module, where a temporal occurrence of the activation and deactivation operations and/or an operating state is predicted for the switching component, and where the prediction is used to perform a correction of the measured value at a prediction time instant or during a prediction time range with respect to the corruption caused by the electromagnetic interference.

Abstract: A method for calibrating an electronic assembly during a manufacturing process is provided, including the steps: determining a calibration value for the assembly which for a predefined input value gives a deviation between an actual output value output by the assembly and a predefined desired output value, transmitting the calibration value to the assembly, and storing the calibration value in the assembly, wherein the calibration value of the assembly is determined by a machine learning method executed in a calibration device, and the machine learning method is trained by training data, which include historical calibration values of a plurality of assemblies of the same type and parameters of assemblies of the same type, which are dependent on the manufacturing process and/or express physical properties.

Abstract: A communication system utilizing unified gateways bridges communication gaps between data transmitters having differing transmission, security, data format, overhead restrictions and performance metrics by dynamically determining optimal data paths for the data being routed. The unified gateways can also dynamically alter data packages to upgrade/downgrade security standards, alter transmission networks, translate data to match recipient requirements and split/combine data to optimize data throughput using disparate systems.

Abstract: The invention relates to a side-channel machine having a housing (4a), located in the housing (4a) a side-channel (28) for guiding a gas, and at least one gas inlet opening (34) which is formed in the housing (4a) and is fluidically connected to the side-channel (28). Furthermore, the side-channel machine has at least one gas inlet pipe (29a) which connects to the at least one gas inlet opening (34), The side-channel machine further comprises at least one gas outlet opening (33) and at least one gas outlet pipe (31a) which connects to the at least one gas outlet opening (33). Furthermore, the side-channel machine has an impeller that can be made to rotate in the housing (4a), with impeller blades, which bound impeller cells arranged in the side-channel (28), for delivering the gas in the impeller cells from the at least one gas inlet opening (34) to the at least one gas outlet opening (33).

Abstract: An electric motor can include a stator body defining fluid channels extending axially for fluid communication between axial ends of the stator body. Conductive windings can form first loops extending axially outward from the first end of the stator body and second loops extending axially outward from the second end of the stator body. A first cap can be coupled to the first end of the stator body and can include a first wall. The first wall can be between the first loops and the channels. Pins can extend from a side of the first wall that is opposite the first loops. The second cap can be coupled to the second end of the stator body and include a second wall. The second wall can be between the second loops and the channels. Pins can extend from a side of the second wall that is opposite the second loops.

Abstract: A live virtual constructive (LVC) gateway system is configured to transparently separate, merge, and route data traffic between operator systems, live tactical Line Replaceable Unit (LRU) systems, and simulated tactical LRU systems. The LVC gateway is configured to receive LRU commands from an operator system, parse, the commands, and reconstruct the commands suitable for transmission to live or simulated tactical LRU systems. The LVC gateway is also configured to receive live and simulated status and target data from live tactical LRU and simulated tactical LRU systems, respectively, and merge the data for transmission to an operator system.

Abstract: An arm module includes a housing with a first connection side controllably rotatable relative to a second connection side, about an axis of rotation. The first connection side has a rotatable first connection device. The second connection side has a second connection device fixed to the housing, with a rotation-compatible data transmission device for transmitting data signals along at least one transmission path between the first and second connection sides. The transmission path includes at least one wireless transmission sub-path for wireless transmission of data signals, and at least one wire-guided transmission sub-path for wire-guided transmission of data signals. The rotation-compatible data transmission device includes at least one first wireless transmission unit and at least one second wireless transmission unit, interconnected via the transmission path and arranged to wirelessly transmit and receive data signals along the wireless transmission sub-path.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: An electric motor can include a stator body defining fluid channels extending axially for fluid communication between axial ends of the stator body. Conductive windings can form first loops extending axially outward from the first end of the stator body and second loops extending axially outward from the second end of the stator body. A first cap can be coupled to the first end of the stator body and can include a first wall. The first wall can be between the first loops and the channels. Pins can extend from a side of the first wall that is opposite the first loops. The second cap can be coupled to the second end of the stator body and include a second wall. The second wall can be between the second loops and the channels. Pins can extend from a side of the second wall that is opposite the second loops.

Abstract: An apparatus and a method for embossing micro- and/or nanostructures include the embossing of the micro- and/or nanostructures in an embossing material.

Abstract: The invention relates to a side-channel machine having a housing (4a), located in the housing (4a) a side-channel (28) for guiding a gas, and at least one gas inlet opening (34) which is formed in the housing (4a) and is fluidically connected to the side-channel (28). Furthermore, the side-channel machine has at least one gas inlet pipe (29a) which connects to the at least one gas inlet opening (34), The side-channel machine further comprises at least one gas outlet opening (33) and at least one gas outlet pipe (31a) which connects to the at least one gas outlet opening (33). Furthermore, the side-channel machine has an impeller that can be made to rotate in the housing (4a), with impeller blades, which bound impeller cells arranged in the side-channel (28), for delivering the gas in the impeller cells from the at least one gas inlet opening (34) to the at least one gas outlet opening (33).

Abstract: The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrimidine-5-carboxamide compounds which may be useful in the treatment or prevention of a disease or medical condition mediated through signaling of CaMK1 isoforms. For example, such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers, metabolic diseases including type-2 diabetes, and/or immune-mediated disorders.

Abstract: Integrating a plurality of third party service interactions into a portal including a Web content management system includes receiving a data structure, associating the data structure with a selected profile out of a plurality of profiles based on the origin of the data structure, and transforming content of the received data structure, using a declarative mapping associated with the selected profile, into an intermediate data structure. The intermediate data structure may be provided to a presentation layer of the portal. A signal causing a rendering of the intermediate data structure may be triggered via a portlet of the portal to a display. Captured input from the portlet from the intermediate data structure may be transformed to the data structure using the declarative mapping associated with the selected profile. The data structure may be sent.

Abstract: Technologies and implementations for a modular sign apparatus having an integrated post driver. The technologies and implementations facilitate assembly of a ground engaging sign including a stake driver for a vertical member of the sign apparatus.

Abstract: An apparatus and a method for embossing micro- and/or nanostructures in an embossing material.

Abstract: Compounds that inhibit KRas G12D; in particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.