Patents by Inventor Peter Gruber

Peter Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240408822
    Abstract: In a method for a lithography-based generative manufacture of a three-dimensional component, a beam is split into a plurality of beams by a beam splitter, said beams being focused onto focal points within a material by means of an optical imaging unit, wherein the focal points are adjusted by means of a deflecting unit which is arranged upstream of the optical imaging unit in the beam direction, whereby a volume element of the material is solidified by means of multi-photon absorption at the focal point of each beam one after the other, and a number of acousto-optical modulator modules, said number corresponding to the number of beams, is provided such that an acousto-optical modulator module is arranged in the beam path of each beam.
    Type: Application
    Filed: September 28, 2022
    Publication date: December 12, 2024
    Applicant: UPNANO GMBH
    Inventor: Peter GRUBER
  • Publication number: 20240123688
    Abstract: In a method of controlling a lithography-based additive manufacturing device capable of manufacturing a three-dimensional component from a plurality of volume elements, a check is made to determine whether the volume elements are entirely within the three-dimensional virtual model by identifying at least first and second boundary points of the volume element or virtual model in x-y planes spaced apart in the z-direction, and the volume element in question is provided for the manufacturing process only if it is within the model with respect to the first and second boundary points.
    Type: Application
    Filed: February 16, 2022
    Publication date: April 18, 2024
    Applicant: TECHNISCHE UNIVERSITÄT WIEN
    Inventors: Peter GRUBER, Aleksandr OVSIANIKOV
  • Patent number: 11931954
    Abstract: A method of producing a test body for diffusion tensor imaging, which comprises a plurality of channels in a structuring material, the channels preferably having a maximum cross-section of 625 ?m2, wherein a virtual model of the test body is created and the virtual model is fed to a structuring device which produces the test body by means of a 3D printing-based, in particular lithography-based, structuring process, the structuring process being designed as a multiphoton lithography process, in particular as a multiphoton absorption process, in which the structuring material containing a photosensitizer or photoinitiator is irradiated in a location-selective manner, wherein the radiation is successively focused on focal points lying within the structuring material, resulting in that in each case a volume element of the material located in the focal point is subjected to a change in state by means of a photochemical reaction as a result of multiphoton absorption.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: March 19, 2024
    Assignee: TECHNISCHE UNIVERSITAT WIEN
    Inventors: Aleksandr Ovsianikov, Peter Gruber, Christian Windischberger, Zoltan Nagy
  • Patent number: 11787106
    Abstract: In a method for the lithography-based generative production of a three-dimensional component, in which electromagnetic radiation emitted by an irradiation device is successively focused on focal points within a material, wherein in each case a volume element of the material located at the focal point is solidified by means of multiphoton absorption, wherein a substructure is each built up from the volume elements in a writing area of the irradiation device, the build-up of the component comprises the following steps: a) a plurality of substructures are arranged next to one another, then b) substructures are arranged one above the other so that upper substructures bridge the interface(s) between lower substructures arranged next to one another.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 17, 2023
    Assignee: UPNANO GMBH
    Inventor: Peter Gruber
  • Publication number: 20230150190
    Abstract: In a method for the lithography-based generative manufacturing of a three-dimensional component, in which at least one beam emitted by an electromagnetic radiation source is successively focused by means of an irradiation device onto focal points within a material, as a result of which in each case a volume element of the material located at the focal point is solidified by means of multiphoton absorption, the focal point is displaced in a z-direction, the z-direction corresponding to a direction of irradiation of the at least one beam into the material, the displacement of the focal point in the z-direction being effected by means of at least one acousto-optical deflector arranged in the beam path, in which a sound wave is generated, the frequency of which is periodically modulated.
    Type: Application
    Filed: March 18, 2021
    Publication date: May 18, 2023
    Inventor: Peter GRUBER
  • Publication number: 20220118691
    Abstract: In a method for the lithography-based generative production of a three-dimensional component, in which electromagnetic radiation emitted by an irradiation device is successively focused on focal points within a material, wherein in each case a volume element of the material located at the focal point is solidified by means of multiphoton absorption, wherein a substructure is each built up from the volume elements in a writing area of the irradiation device, the build-up of the component comprises the following steps: a) a plurality of substructures are arranged next to one another, then b) substructures are arranged one above the other so that upper substructures bridge the interface(s) between lower substructures arranged next to one another.
    Type: Application
    Filed: February 26, 2020
    Publication date: April 21, 2022
    Inventor: Peter GRUBER
  • Publication number: 20220111581
    Abstract: A method of producing a test body for diffusion tensor imaging, which comprises a plurality of channels in a structuring material, the channels preferably having a maximum cross-section of 625 ?m2, wherein a virtual model of the test body is created and the virtual model is fed to a structuring device which produces the test body by means of a 3D printing-based, in particular lithography-based, structuring process, the structuring process being designed as a multiphoton lithography process, in particular as a multiphoton absorption process, in which the structuring material containing a photosensitizer or photoinitiator is irradiated in a location-selective manner, wherein the radiation is successively focused on focal points lying within the structuring material, resulting in that in each case a volume element of the material located in the focal point is subjected to a change in state by means of a photochemical reaction as a result of multiphoton absorption.
    Type: Application
    Filed: December 20, 2019
    Publication date: April 14, 2022
    Applicant: Medizinishce Universitat Wien
    Inventors: Aleksandr OVSIANIKOV, Peter GRUBER, Christian WINDISCHBERGER, Zoltan NAGY
  • Publication number: 20220000785
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: September 17, 2021
    Publication date: January 6, 2022
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • Publication number: 20200188303
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: February 20, 2020
    Publication date: June 18, 2020
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • Patent number: 10603280
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: March 31, 2020
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • Publication number: 20190255773
    Abstract: In a method for lithography-based generative production of three-dimensional components, in which material that can be solidified under the effect of electromagnetic radiation is arranged in a vat, a build platform is positioned at a distance from the vat bottom, material located between the build platform and the vat bottom is irradiated at selected locations with the aid of an irradiating unit, the electromagnetic radiation is introduced into the material from below through a vat bottom that is transmissive to the radiation, at least in a certain region, and successively focused on focal points within the material, whereby a volume element of the material that is respectively located at the focal point is solidified. The solidification takes place by means of multiphoton absorption and the volume of the focal point is varied at least once during the method, and so the component is built up from solidified volume elements of different volumes.
    Type: Application
    Filed: July 6, 2017
    Publication date: August 22, 2019
    Inventors: Aleksandr OVSIANIKOV, Jürgen STAMPFL, Robert LISKA, Peter GRUBER
  • Publication number: 20190105273
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: December 7, 2018
    Publication date: April 11, 2019
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • Patent number: 10206879
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: February 19, 2019
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • Publication number: 20180000739
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: September 15, 2017
    Publication date: January 4, 2018
    Applicant: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • Patent number: 9775807
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: October 3, 2017
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • Publication number: 20160038283
    Abstract: Apparatus and methods for transcatheter valves. Specific embodiments relate to transcatheter flutter valves configured for pediatric use.
    Type: Application
    Filed: August 6, 2015
    Publication date: February 11, 2016
    Applicant: THE UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Abhay DIVEKAR, Osamah ALDOSS, Joseph TUREK, Peter GRUBER
  • Patent number: 9205054
    Abstract: A process for producing a solubilized ibuprofen, preferably in the form of a granulate, the process comprising the steps of: providing a mixture comprising solid ibuprofen and a first base selected from the group consisting of sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate, sodium glycinate, potassium glycinate and tribasic sodium and potassium phosphates and mixtures thereof, and reacting the ibuprofen and the first base in essentially dry state. The obtainable granulate and the pharmaceutical compositions and dosage forms that may be produced therefrom are distinguished by their high solubility and rapid disintegration and dissolution in aqueous media, by their good flow properties and compressibility, by rapidly achieving onset of analgesic effect.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: December 8, 2015
    Assignee: LOSAN PHARMA GMBH
    Inventors: Peter Gruber, Wolfgang Mohr
  • Publication number: 20150150797
    Abstract: An orally administrable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutically tolerable salt or a derivative thereof.
    Type: Application
    Filed: December 2, 2014
    Publication date: June 4, 2015
    Inventors: Norbert Otterbeck, Peter Gruber
  • Patent number: 8956647
    Abstract: An orally administrable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutically tolerable salt or a derivative thereof.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: February 17, 2015
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Norbert Otterbeck, Peter Gruber
  • Patent number: 8940328
    Abstract: An orally administrable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutically tolerable salt or a derivative thereof.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: January 27, 2015
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Norbert Otterbeck, Peter Gruber