Patents by Inventor Peter H.R. Persicaner

Peter H.R. Persicaner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20240358839
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: November 22, 2023
    Publication date: October 31, 2024
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick, Neda IRANI
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20240115584
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: September 15, 2023
    Publication date: April 11, 2024
    Applicant: TherapeuticsMD, Inc..
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio, Frederick D. Sancilio
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 11497709
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: November 15, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia Amadio, Peter H.R. Persicaner
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20220040307
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: June 15, 2021
    Publication date: February 10, 2022
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick, Neda IRANI
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200323881
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 15, 2020
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20200281941
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 10, 2020
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20200268888
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: September 20, 2019
    Publication date: August 27, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200171050
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: January 27, 2020
    Publication date: June 4, 2020
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20190381068
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: February 12, 2019
    Publication date: December 19, 2019
    Applicant: TherapeuticsMD, Inc.
    Inventors: Julia AMADIO, Brian Bernick, Peter H.R. Persicaner
  • Natural combination hormone replacement formulations and therapies
    Publication number: 20190343845
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 14, 2019
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20190314386
    Abstract: Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil.
    Type: Application
    Filed: January 9, 2019
    Publication date: October 17, 2019
    Inventors: Brian A. Bernick, Peter H.R. Persicaner, Julia M. Amadio
  • Natural combination hormone replacement formulations and therapies
    Publication number: 20190142844
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: August 16, 2018
    Publication date: May 16, 2019
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20180161345
    Abstract: In one aspect, pharmaceutical compositions and methods for the treatment of vulvovaginal atrophy (VVA) are provided. In one embodiment, the method comprises digitally inserting into the lower third of the vagina of a subject having VVA a soft gelatin capsule containing a liquid pharmaceutical composition.
    Type: Application
    Filed: February 9, 2018
    Publication date: June 14, 2018
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H.R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20170340739
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: March 9, 2017
    Publication date: November 30, 2017
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20170000803
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: September 6, 2016
    Publication date: January 5, 2017
    Applicant: TherapeuticsMD, Inc.
    Inventors: Julia Amadio, Brian Bernick, Peter H.R. Persicaner
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20160213685
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: April 4, 2016
    Publication date: July 28, 2016
    Inventors: BRIAN A. BERNICK, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20150359737
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: June 18, 2013
    Publication date: December 17, 2015
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150352126
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: August 19, 2015
    Publication date: December 10, 2015
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150342963
    Abstract: Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil.
    Type: Application
    Filed: May 22, 2015
    Publication date: December 3, 2015
    Inventors: Brian A. Bernick, Peter H.R. Persicaner, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20150224117
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: April 20, 2015
    Publication date: August 13, 2015
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio